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Merck

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Namestring
Merck
Legal namestring
Merck & Co., Inc., Rahway, NJ, USA
Websiteurl
merck.com
Company typeenum
Public
Founded yearint
1891
Descriptiontext

Merck & Co., Inc. (NYSE: MRK) is a US-headquartered, publicly traded research-intensive biopharmaceutical company founded in 1891 in New York City by George Merck and now headquartered in Rahway, NJ. The company develops, manufactures, and commercializes prescription medicines and vaccines across six therapeutic franchises: oncology (anchored by Keytruda, the first anti-PD-1 therapy approved in 2014, deployed across 30+ tumor types and now combined with Welireg, Padcev, Trodelvy, sac-TMT, and Moderna's intismeran autogene), vaccines (Gardasil, Capvaxive, M-M-R, Pneumovax, Recombivax HB, Ervebo), infectious diseases (35+ years of HIV research, Lagevrio, AMR Action Fund), cardiometabolic and respiratory (Januvia, plus Verona Pharma-derived pulmonary assets), immunology (tulisokibart anti-TL1A acquired via the $10.8B Prometheus deal), and animal health (Bravecto, 70+ year franchise). The company operates Merck Animal Health as a separate global business unit and runs Merck Research Laboratories with approximately 24,700 R&D employees and $15.8B in R&D investment in 2025.

Merck's underlying technology platform is a multi-modality R&D engine spanning small molecules, biologics, antibody-drug conjugates, macrocyclic peptides, mRNA-based individualized neoantigen therapies, and AI-driven protein engineering, supported by the proprietary TEDDY family of AI models trained on more than 100 million single cells and partnerships with Tempus AI (45M+ de-identified patient records), Protillion Biosciences (Prot-MaP AI platform), and Google Cloud ($1B AI infrastructure partnership). The portfolio is anchored by Keytruda, which generated $8.0B in Q1 2026 (+8% YoY) and $8.37B in Q4 2025, and is being defended against the 2028 IV patent cliff through the September 2025 launch of subcutaneous Keytruda Qlex (with patent estate potentially extending to 2042) and aggressive M&A totaling $40B+ since 2023 across Cidara, Terns, Verona Pharma, Prometheus, Imago, Modifi Bio, Eyebiotech, Harpoon, Caraway, Acceleron, Pandion, and others.

Merck's business model is B2B/B2B2C pharmaceutical sales through direct specialty field forces (oncology, specialty pharma/infectious diseases, animal health), authorized distributor networks, co-promotion partnerships (Astellas for Padcev, Gilead for Trodelvy and once-weekly oral HIV), and patient assistance programs. Revenue is overwhelmingly generated by pharmaceutical and vaccine product sales, with collaboration/licensing income (Moderna, Gilead, Daiichi Sankyo), animal health sales, and philanthropic channels (Merck Medical Outreach Program, Impact Venture Fund) as supplementary streams. 2026 full-year revenue guidance is $65.5-67.0B. Merck also reaches >450M people with medicines and vaccines across 92% of countries, with notable impact-investing and global health programs including the 35-year Mectizan donation for river blindness, Merck for Mothers (>9M women in 48 countries), and a $55M Impact Venture Fund.

Short descriptiontext

Merck & Co., Inc. is a US-headquartered biopharmaceutical company that develops and commercializes prescription medicines and vaccines across oncology, vaccines, infectious diseases, immunology, cardiometabolic, and animal health, anchored by the Keytruda immuno-oncology franchise and a global multi-modality R&D engine.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
5,001–10,000
akta.pro rankint
HeadquartersRahway, United States
HQ citystring
Rahway
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Offices9 records

Each record includes

City, Country, Type, Description, Source

Keyword5 values
biopharmaceutical medicines, oncology therapies, vaccines and prevention, immuno-oncology drugs, animal health products
Industry5 codes
1Veterinary Vaccines (Biologics)
CodeHLAMAEALPrimaryYes
2Veterinary Vaccines
CodeHLAIAEAHPrimaryNo
3Livestock & Production Animal Therapeutics (Rx)
CodeHLAMAEABPrimaryNo
4Companion Animal Vaccines (Dogs & Cats)
CodeHLAMAKAAPrimaryNo
5Livestock Vaccines (Cattle, Swine, Sheep & Goats)
CodeHLAMAKABPrimaryNo
NAICS code3 codes
  • Biological Product (except Diagnostic) Manufacturing325414
  • Veterinary Services54194
  • Veterinary Services541940
SIC code2 codes
  • Biological Products, (No Disgnostic Substances)2836
  • Wholesale-Drugs, Proprietaries & Druggists' Sundries5122
Product category
Biopharmaceuticals
GTM motion4 records

Each record includes

Type, Description, Source

Revenue model5 records
1Pharmaceutical product sales (human health)
TypeHardware Sales
Description

Primary revenue stream from sales of patented prescription medicines and vaccines including Keytruda, Gardasil, Januvia, Keytruda Qlex, Welireg, Capvaxive, and a broad oncology, vaccines, infectious disease, and cardiometabolic/respiratory portfolio. Keytruda alone generated $8.0B in Q1 2026 (8% YoY growth) and $8.37B in Q4 2025. 2026 revenue guidance: $65.5-67.0B.

merck.com
2Animal Health product sales
TypeHardware Sales
Description

Merck Animal Health sells veterinary pharmaceuticals, vaccines, and health management solutions/digital products for livestock and companion animals (e.g., Bravecto). Operates as a separate global business unit with its own distribution network and 70+ year history.

merck.com
3Collaboration and licensing income (incl. co-development milestone payments)
TypeLicensing Royalties
Description

Revenue from strategic co-development partnerships including Moderna (mRNA-4157), Gilead (islatravir/lenacapavir once-weekly HIV), Daiichi Sankyo (ADC programs), and Astellas (Padcev combination). Includes upfront payments, R&D milestones, and royalty/profit-share arrangements.

stocktitan.net
4Merck Medical Outreach Program (product donations)
TypeManaged Services
Description

Charitable product donation program (65+ years) channeling pharmaceuticals and vaccines through qualified NGO partners (AmeriCares, CMMB, Direct Relief, MAP International, Partners In Health, Project HOPE) to low- and middle-income countries and disaster relief. Not a commercial revenue stream but tracked for impact metrics.

merck.com
5Investment income (Impact Venture Fund)
TypeAffiliate Referral
Description

$55M+ of venture capital investments via Impact Venture Fund into funds/companies addressing health access in LMICs. Returns are recycled into new investments; impact reaches 35M+ people cumulatively since 2018.

Distribution channels6 records

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components6 values
Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Infrastructure
Pricing details1 tier
1Negotiated unit pricing with payers/governments; 3% dividend yield to shareholders; A+ credit rating.
ModelUnit PricingBilling cadencePay-as-you-go
Notes

Not publicly disclosed; pricing is quote-based/negotiated with payers, government programs, and 340B institutions. Shareholders receive a 3% dividend yield; stock has a normalized forward P/E of 12.0.

seekingalpha.com
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Brand1 of 3 records shown
1Merck Animal Health
Description

Global animal health business unit offering veterinary pharmaceuticals, vaccines, and health management solutions for livestock and companion animals, with over 70 years of history.

merck.com
+2 more records
Core offering1 text field

Merck is a global biopharmaceutical company that discovers, develops, manufactures, and commercializes prescription medicines and vaccines for human health, alongside veterinary pharmaceuticals, vaccines, and connected health technologies for animal health through its Merck Animal Health division. Its commercial portfolio is anchored by the KEYTRUDA immuno-oncology franchise and combination regimens, a broad vaccines portfolio (GARDASIL, CAPVAXIVE, ERVEBO, M-M-R, PNEUMOVAX, RECOMBIVAX HB), the Lagevrio COVID-19 antiviral, JANUVIA for Type 2 diabetes, tulisokibart for ulcerative colitis, and BRAVECTO and other parasiticide products for companion animals.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 7 values shown
  • 35% reduction in risk of disease progression or death with Keytruda + Trodelvy vs Keytruda + chemo in 1L PD-L1+ mTNBC (median PFS 11.2 vs 7.8 months)
+6 more records
Product overview1 text field

Merck operates a multi-franchise biopharmaceutical portfolio rather than a single unified product, anchored by the KEYTRUDA immuno-oncology franchise — including the IV KEYTRUDA backbone, the subcutaneous KEYTRUDA QLEX co-formulation, and combination partners such as WELIREG, Padcev, Trodelvy, and Moderna's intismeran autogene (mRNA-4157). Its vaccines franchise spans GARDASIL (HPV), CAPVAXIVE (pneumococcal), ERVEBO (Ebola Zaire), M-M-R, PNEUMOVAX, and RECOMBIVAX HB, while infectious-disease and cardiometabolic franchises include Lagevrio for COVID-19 and JANUVIA for Type 2 diabetes. Animal Health is represented by BRAVECTO and is being expanded into biodevices via the announced TARGAN acquisition. Pipeline and acquired assets layered on top include tulisokibart (anti-TL1A, ex-Prometheus), TERN-701 (ex-Terns), CD388 (ex-Cidara), the islatravir + lenacapavir HIV combination with Gilead, and the personalized cancer vaccine program with Moderna. Underpinning this portfolio is M-Trust, Merck's physical authentication technology, which integrates with The Hashgraph Group's TrackTrace Digital Product Passport on the Hedera network to secure regulated pharmaceutical supply chains, and Merck's broader AI stack (TEDDY models, Prot-MaP via Protillion, and expanded AI partnerships) which supports discovery and translational research across the franchise.

Product and service17 records
1KEYTRUDA (pembrolizumab)
CategoryCore pharmaceutical product (oncology)
Description

Merck's flagship anti-PD-1 checkpoint inhibitor, initially FDA approved in 2014 and used across more than two dozen tumor types as monotherapy and backbone of multiple combination regimens (with Padcev, WELIREG, Trodelvy, mRNA-4157). Q1 2026 sales of $8.0B; Q4 2025 sales of $8.37B.

2KEYTRUDA QLEX (pembrolizumab and berahyaluronidase alfa-pmph)
CategorySubcutaneous reformulation of a core product
Description

Subcutaneous co-formulation of pembrolizumab with the hyaluronidase enzyme berahyaluronidase alfa-pmph, designed to shorten administration time versus IV KEYTRUDA while preserving efficacy; approved alongside IV KEYTRUDA in combination regimens such as the first-line TNBC regimen with Trodelvy.

3WELIREG (belzutifan)
CategoryCore pharmaceutical product (oncology)
Description

HIF-2α inhibitor approved in combination with KEYTRUDA for adjuvant and advanced renal cell carcinoma and used as the combination backbone in Merck's expanding RCC franchise. 41% sales growth to $716M in 2025; Leerink projects $3.4B by 2028.

4Tulisokibart (MK-7240)
CategoryInvestigational pharmaceutical product (immunology)
Description

Anti-TL1A monoclonal antibody acquired through Merck's Prometheus Biosciences transaction; reported positive Phase 3 results in moderate-to-severe ulcerative colitis in June 2026 (first anti-TL1A biologic to demonstrate Phase 3 UC clinical remission), positioning it as a late-stage immunology candidate being evaluated across 7 disease indications.

5JANUVIA (sitagliptin)
CategoryCore pharmaceutical product (cardiometabolic)
Description

DPP-4 inhibitor for the treatment of Type 2 diabetes, one of Merck's established cardiometabolic franchises facing patent expiration contributing to the ~$2.5B 2026 generic/Medicare impact.

6GARDASIL
CategoryCore vaccine (HPV)
Description

Merck's HPV vaccine, a foundational product in the vaccines franchise for the prevention of HPV-related cancers and diseases. Subject of Merck's Gardasil lawsuit settlement of approximately $50 million.

7CAPVAXIVE
CategoryCore vaccine (pneumococcal)
Description

Pneumococcal 21-valent Conjugate Vaccine; originally approved for adults and subsequently expanded by FDA to at-risk pediatric populations; covers ~79% of invasive pneumococcal disease serotypes in at-risk children.

8ERVEBO
CategoryCore vaccine (Ebola Zaire)
Description

Merck's Ebola Zaire vaccine, used as part of Merck's infectious-disease vaccines portfolio.

9M-M-R (measles-mumps-rubella vaccine)
CategoryCore vaccine (pediatric combination)
Description

Combination measles-mumps-rubella vaccine, a long-established Merck vaccine product.

10PNEUMOVAX
CategoryCore vaccine (pneumococcal polysaccharide)
Description

Pneumococcal polysaccharide vaccine for adult pneumococcal disease prevention.

11RECOMBIVAX HB
CategoryCore vaccine (hepatitis B)
Description

Merck's recombinant hepatitis B vaccine.

12Lagevrio (molnupiravir)
CategoryCore pharmaceutical product (antiviral, infectious disease)
Description

Oral antiviral authorized for the treatment of mild-to-moderate COVID-19 in at-risk adults; also being offered as a potential countermeasure in a WHO-led DRC Ebola trial.

13BRAVECTO
CategoryCore animal-health product
Description

Flagship Merck Animal Health parasiticide brand for dogs and cats providing long-duration flea and tick protection.

14TERN-701
CategoryAcquired pipeline asset (allosteric BCR-ABL inhibitor)
Description

Allosteric BCR-ABL inhibitor for chronic myeloid leukemia (CML), obtained through Merck's acquisition of Terns Pharmaceuticals and integrated into Merck's oncology pipeline.

15CD388
CategoryAcquired pipeline asset (long-acting influenza prevention)
Description

Long-acting influenza prevention candidate acquired via the announced acquisition of Cidara Therapeutics, intended to anchor Merck's antiviral franchise.

16Islatravir + lenacapavir (oral HIV combination)
CategoryInvestigational partnered product (HIV)
Description

Once-weekly oral combination of Merck's islatravir (nucleoside reverse transcriptase translocation inhibitor) and Gilead's lenacapavir for heavily treatment-experienced adults with multidrug-resistant HIV-1; reported positive Phase 3 results in June 2026 and, if approved, would be the first long-acting oral HIV treatment taken once weekly.

17Intismeran autogene (mRNA-4157 / V940)
CategoryInvestigational partnered product (personalized mRNA cancer vaccine)
Description

Personalized neoantigen mRNA cancer vaccine co-developed with Moderna, combined with KEYTRUDA in resected high-risk melanoma; Phase 2b KEYNOTE-942 five-year data showed 49% reduction in recurrence or death and 59% reduction in distant metastasis; 9 Phase 2/3 trials underway across melanoma, NSCLC, bladder cancer, and RCC.

Scale indicator15 records

Each record includes

Type, Value, Description, Source

Partnership33 partners
Strategic tierFlagshipTypeStrategic or Co-development PartnerAnnounced on2026-06-24
Description

Multiple co-development programs: (1) Trodelvy (sacituzumab govitecan-hziy) + Keytruda combination approved in 1L PD-L1+ metastatic TNBC (June 2026) and under EU review; (2) Once-weekly oral HIV treatment islatravir/lenacapavir met primary efficacy in Phase 3 ISLEND-1 and ISLEND-2; (3) Lung cancer combo trial KEYNOTE-D46/EVOKE-03 discontinued. Relationship is mutual co-development.

Strategic tierFlagshipTypeStrategic or Co-development PartnerAnnounced on2026-06-24
Description

Co-promotion of Padcev (enfortumab vedotin) + Keytruda (pembrolizumab) combination as perioperative treatment for adults with resectable muscle-invasive bladder cancer who are ineligible for cisplatin. EU approval June 2026 based on Phase 3 KEYNOTE-905 showing 60% reduction in EFS events and 50% reduction in death risk vs surgery alone.

Strategic tierCoreTypeStrategic or Co-development PartnerAnnounced on2026-06-24
Description

Co-development of ADC programs including ifinatamab deruxtecan (B7-H3 ADC). Daiichi appointed John Tsai as head of R&D to execute 5-year plan to become a top-5 oncology company by 2035. Merck is referenced as a key ADC partner alongside AstraZeneca.

Strategic tierMinorTypeStrategic or Co-development PartnerAnnounced on2026-06-24
Description

Merck is offering its antiviral molnupiravir (Lagevrio) as a potential countermeasure in a WHO-led DRC Ebola trial testing MBP134 and remdesivir against Bundibugyo ebolavirus. Outbreak has caused 1,094 confirmed cases and 277 deaths.

Strategic tierMinorTypeGTM or Marketing PartnerAnnounced on2026-06-23
Description

Multi-state partnership through Merck for Mothers initiative to expand and sustain the community-based doula workforce in California, Georgia, Illinois, and Texas. Provides doula training, professional development, and administrative support to help community doulas achieve Medicaid participation.

Strategic tierMinorTypeStrategic or Co-development PartnerAnnounced on2026-06-22
Description

Clinical development collaboration for the STELLAR-316 trial evaluating zanzalintinib combination in metastatic colorectal cancer.

Strategic tierMinorTypeStrategic or Co-development PartnerAnnounced on2026-06-17
Description

Clinical combination partnership evaluating NTX1088 (first-in-class anti-CD155 antibody) + Keytruda in 91 patients with advanced solid tumors; Phase 1a/1b data presented at ASCO 2026.

Strategic tierCoreTypeTechnology or IntegrationAnnounced on2026-06-16
Description

Multi-target drug discovery collaboration and license agreement. Merck gets access to Prot-MaP AI platform for designing biologic therapies across multiple undisclosed indications. Protillion eligible for up to $510M in R&D and commercial milestone payments.

Strategic tierFlagshipTypeStrategic or Co-development PartnerAnnounced on2026-06-15
Description

Merck acquiring Terns Pharmaceuticals for approximately $6.7B (announced March 2026; ~$5.7B net of acquired cash; 31% premium to 60-day VWAP). Brings lead candidate TERN-701, an investigational oral allosteric BCR::ABL1 tyrosine kinase inhibitor in Phase 1/2 for chronic myeloid leukemia (FDA Orphan Drug Designation March 2024). Expected to close in Q2 2026.

Strategic tierCoreTypeTechnology or IntegrationAnnounced on2026-06-11
Description

Companion diagnostic partnership: Roche's VENTANA MMR RxDx Panel received EU IVDR approval as a companion diagnostic for Keytruda (Merck) across 5 cancer types and 6 indications, alongside IMFINZI/LYNPARZA (AstraZeneca) and JEMPERLI (GSK). Validates patient selection for Keytruda therapy.

Strategic tierMinorTypeStrategic or Co-development PartnerAnnounced on2026-06-11
Description

Definitive agreement by Merck Animal Health to acquire Targan, a privately held company developing biodevice solutions for the poultry industry. Deal expected to close in Q3 2026 pending regulatory approvals.

Strategic tierCoreTypeTechnology or IntegrationAnnounced on2026-06-02
Description

Co-developed PD-L1 IHC 22C3 pharmDx companion diagnostic on Dako Omnis platform for Keytruda. FDA approved expansion to 4 additional cancer types (esophageal SCC, TNBC, cervical, gastric/GEJ adenocarcinoma), enabling consolidated PD-L1 testing across tumor types.

Strategic tierFlagshipTypeStrategic or Co-development PartnerAnnounced on2026-06-01
Description

Co-development of intismeran autogene (mRNA-4157) individualized neoantigen therapy combined with Keytruda. 5-year Phase 2b KEYNOTE-942 data showed 49% reduction in melanoma recurrence/death and 59% reduction in distant metastasis. 9 total Phase 2/3 trials underway across melanoma, NSCLC, bladder cancer, and renal cell carcinoma. Phase 3 INTerpath trial ongoing.

Strategic tierCoreTypeStrategic or Co-development PartnerAnnounced on2026-06-01
Description

Co-developer of sacituzumab tirumotecan (sac-TMT) TROP2-directed antibody-drug conjugate. Phase 3 data in 1L NSCLC showed 80.4% 1-year OS with sac-TMT+Keytruda vs 68.9% for Keytruda monotherapy; 70% ORR; 65% reduced tumor progression risk. Phase 3 TroFuse-005 in endometrial cancer met OS and PFS endpoints.

Strategic tierCoreTypeGTM or Marketing PartnerAnnounced on2026-05-15
Description

Expanded global partnership to strengthen women's cancer care. Initiative aims to reach more than 300,000 women living with cancer around the world by 2030.

Strategic tierFlagshipTypeStrategic or Co-development PartnerAnnounced on2025-11-14
Description

Merck agreed to acquire Cidara Therapeutics for approximately $9.2B to develop CD388, a long-acting antiviral drug for influenza prevention (Phase III). Part of Merck's strategy to diversify beyond Keytruda's patent cliff.

Strategic tierCoreTypeStrategic or Co-development PartnerAnnounced on2022-11-22
Description

Merck acquired Imago BioSciences for approximately $1.35B in all-cash deal (closed Q1 2023) to strengthen pipeline in hematology through development of medicines for myeloproliferative neoplasms (MPNs) and other bone marrow diseases.

Strategic tierCoreTypeOthers
Description

Qualified NGO partner receiving Merck pharmaceutical and vaccine donations through the Merck Medical Outreach Program (65+ years) for humanitarian assistance in LMICs and disaster relief worldwide.

Strategic tierCoreTypeOthers
Description

Qualified NGO partner in the Merck Medical Outreach Program receiving pharmaceutical and vaccine donations for humanitarian use in LMICs.

Strategic tierCoreTypeOthers
Description

Qualified NGO partner receiving Merck Medical Outreach Program donations of medicines and vaccines for humanitarian programs in low- and middle-income countries.

Strategic tierCoreTypeOthers
Description

Qualified NGO partner in Merck's Medical Outreach Program; receives pharmaceutical and vaccine donations for distribution in LMICs and disaster relief.

Strategic tierCoreTypeOthers
Description

Qualified NGO partner in Merck's Medical Outreach Program receiving pharmaceutical donations for distribution in low- and middle-income countries.

Strategic tierCoreTypeOthers
Description

Qualified NGO partner receiving Merck Medical Outreach Program donations of pharmaceuticals and vaccines for humanitarian assistance in developing countries.

Strategic tierMinorTypeOthers
Description

Impact investing partnership supporting acceleration of critical health care commodities for vulnerable children in limited-resource settings.

Strategic tierCoreTypeTechnology or Integration
Description

Data partnership with AI-enabled precision medicine company. Leverages 45M+ de-identified patient records and 500+ petabytes of data. Individual deal values reaching up to $320M. AstraZeneca and GSK also cited as Tempus partners.

Strategic tierFlagshipTypeStrategic or Co-development Partner
Description

Acquired by Merck for $10.8-11B in 2023. Lead program tulisokibart (MK-7240), an anti-TL1A monoclonal antibody, met primary endpoint of clinical remission at week 12 in Phase 3 ATLAS-UC induction-only study for ulcerative colitis - first anti-TL1A biologic to achieve this milestone. Being evaluated across 7 disease indications.

27N.C. A&T (North Carolina Agricultural and Technical State University)
Strategic tierMinorTypeStrategic or Co-development Partner
Description

Partnership to launch a collaborative biotechnology learning center as a foundation for future talent development.

merck.com
Strategic tierCoreTypeStrategic or Co-development Partner
Description

Pfizer is continuing a late-stage study testing sigvotatug vedotin in combination with Merck's Keytruda as a first-line treatment for NSCLC. Combinatorial use of Keytruda as backbone in lung cancer studies.

Strategic tierMinorTypeStrategic or Co-development Partner
Description

Cooperation agreement covering Ukko's RNA-based peanut allergy therapy (Ukko18) and Aulos Bioscience's AI-designed cancer immunotherapy. Ukko and Aulos Biolojic Design have raised over $200M for research combined.

Strategic tierCoreTypeTechnology or Integration
Description

$1B partnership with Google Cloud for AI infrastructure, referenced alongside Merck's broader AI agenda including the Protillion Biosciences AI drug discovery collaboration.

Strategic tierMinorTypeGTM or Marketing Partner
Description

Merck executives participating in the 2nd annual Partnerships with Sites Summit (September 14, 2026, Boston), alongside Eli Lilly, Biogen, Novartis, AstraZeneca, Sanofi, and Takeda to address clinical trial system challenges costing the industry ~$50B annually.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Merck committed $100M over 10 years to the AMR Action Fund, a partnership of 20+ leading pharmaceutical companies, philanthropies, and organizations aimed at bringing 2-4 novel antibiotics to patients and physicians by 2030.

Strategic tierFlagshipTypeStrategic or Co-development Partner
Description

Clinical trials for HIV treatment involving islatravir/lenacapavir (once-weekly oral HIV treatment) - if approved, would be the first long-acting oral HIV treatment taken once weekly. Per Cantor Fitzgerald, positive outcomes were observed.

Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight4 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

Direct PD-1/PD-L1 oncology competitor with Opdivo (nivolumab) competing head-to-head with Keytruda across multiple tumor types. Similar large-cap biopharma profile with comparable oncology, immunology, and cardiovascular franchises.

TypeDirect peer
Description

Direct oncology competitor with Tecentriq (PD-L1) plus deep companion diagnostic footprint. Roche's VENTANA MMR RxDx Panel is a CDx for Keytruda, illustrating the intertwined competitive and partnership dynamics across immuno-oncology.

TypeDirect peer
Description

Direct PD-L1 competitor (Imfinzi/durvalumab) and ADC platform partner alongside Daiichi Sankyo. Competes with Merck in lung, breast, and GI oncology while sharing the ADC modality frontier.

TypeBroad incumbent
Description

Comparable large-cap biopharma with overlapping oncology, vaccines, and infectious disease franchises. Currently combining its sigvotatug vedotin with Merck's Keytruda in NSCLC trials, illustrating both competitive overlap and partnership dynamics.

TypeBroad incumbent
Description

Similar large-cap biopharma competing across oncology, immunology, cardiometabolic, and neuroscience. Lilly's tirzepatide/Verona-style acquisition strategy and oncology pipeline expansion parallel Merck's M&A-driven approach.

TypeBroad incumbent
Description

Comparable global biopharma with strong oncology (Pluvicto, Kisqali), cardiovascular, and immunology franchises. Competes directly in radioligand therapy and CDK4/6 inhibitor spaces adjacent to Merck's oncology pipeline.

TypeBroad incumbent
Description

Diversified large-cap with a sizable Innovative Medicine pharmaceutical segment overlapping Merck's oncology, immunology, and infectious disease franchises. J&J's Darzalex and oncology pipeline compete for the same oncologists and indications.

TypeBroad incumbent
Description

Comparable large-cap biopharma that has navigated a major Humira patent cliff via Skyrizi/Rinvoq and aggressive M&A (Allergan, ImmunoGen, Cerevel). Provides a useful precedent for managing large patent-cliff transitions.

TypeBroad incumbent
Description

Global biopharma with overlapping immunology (Dupixent), vaccines, and rare disease franchises. Competes with Merck in inflammatory bowel disease and is an established vaccines peer.

10GSK
TypeBroad incumbent
Description

Direct competitor in vaccines (Shingrix, HPV, pneumococcal), HIV (ViiV Healthcare), and oncology (Jemperli PD-1 inhibitor). GSK's oncology pipeline competes with Merck in endometrial and other gynecologic cancers.

Market position
Strengths5 records

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Headline, Details, Source

Weaknesses5 records

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Headline, Details, Source

Competitive moat7 records

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Type, Details

Key risks7 records

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Headline, Details, Source

Key highlights7 records

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Customer concentration

Classification, Details

Named customers10 records

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Name, Industry, Type, Use case, Source, UUID

Segment8 records

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Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile4 records

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Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

Integration2 records

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Title, Type, Description, Source

AI capability10 records

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Type, Description, Source

AI maturity
App detail

Has app

Feature9 records

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Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles27 records

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Name, Designation, Designation category, Overview, Profile commentary, Source

Subsidiaries6 records

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Name, Acquired on, Relationship type, Type, Business focus

No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds2 records

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Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors2 records

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Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A42 records

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment35 records

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Merck

Biopharmaceuticalsmerck.com

Merck & Co., Inc. is a US-headquartered biopharmaceutical company that develops and commercializes prescription medicines and vaccines across oncology, vaccines, infectious diseases, immunology, cardiometabolic, and animal health, anchored by the Keytruda immuno-oncology franchise and a global multi-modality R&D engine.

What Merck does

Merck & Co., Inc. (NYSE: MRK) is a US-headquartered, publicly traded research-intensive biopharmaceutical company founded in 1891 in New York City by George Merck and now headquartered in Rahway, NJ. The company develops, manufactures, and commercializes prescription medicines and vaccines across six therapeutic franchises: oncology (anchored by Keytruda, the first anti-PD-1 therapy approved in 2014, deployed across 30+ tumor types and now combined with Welireg, Padcev, Trodelvy, sac-TMT, and Moderna's intismeran autogene), vaccines (Gardasil, Capvaxive, M-M-R, Pneumovax, Recombivax HB, Ervebo), infectious diseases (35+ years of HIV research, Lagevrio, AMR Action Fund), cardiometabolic and respiratory (Januvia, plus Verona Pharma-derived pulmonary assets), immunology (tulisokibart anti-TL1A acquired via the $10.8B Prometheus deal), and animal health (Bravecto, 70+ year franchise). The company operates Merck Animal Health as a separate global business unit and runs Merck Research Laboratories with approximately 24,700 R&D employees and $15.8B in R&D investment in 2025.

Merck's underlying technology platform is a multi-modality R&D engine spanning small molecules, biologics, antibody-drug conjugates, macrocyclic peptides, mRNA-based individualized neoantigen therapies, and AI-driven protein engineering, supported by the proprietary TEDDY family of AI models trained on more than 100 million single cells and partnerships with Tempus AI (45M+ de-identified patient records), Protillion Biosciences (Prot-MaP AI platform), and Google Cloud ($1B AI infrastructure partnership). The portfolio is anchored by Keytruda, which generated $8.0B in Q1 2026 (+8% YoY) and $8.37B in Q4 2025, and is being defended against the 2028 IV patent cliff through the September 2025 launch of subcutaneous Keytruda Qlex (with patent estate potentially extending to 2042) and aggressive M&A totaling $40B+ since 2023 across Cidara, Terns, Verona Pharma, Prometheus, Imago, Modifi Bio, Eyebiotech, Harpoon, Caraway, Acceleron, Pandion, and others.

Merck's business model is B2B/B2B2C pharmaceutical sales through direct specialty field forces (oncology, specialty pharma/infectious diseases, animal health), authorized distributor networks, co-promotion partnerships (Astellas for Padcev, Gilead for Trodelvy and once-weekly oral HIV), and patient assistance programs. Revenue is overwhelmingly generated by pharmaceutical and vaccine product sales, with collaboration/licensing income (Moderna, Gilead, Daiichi Sankyo), animal health sales, and philanthropic channels (Merck Medical Outreach Program, Impact Venture Fund) as supplementary streams. 2026 full-year revenue guidance is $65.5-67.0B. Merck also reaches >450M people with medicines and vaccines across 92% of countries, with notable impact-investing and global health programs including the 35-year Mectizan donation for river blindness, Merck for Mothers (>9M women in 48 countries), and a $55M Impact Venture Fund.

Merck firmographics

Firmographics
Name
Merck
Legal name
Merck & Co., Inc., Rahway, NJ, USA
Website
https://merck.com
Company type
Public
Founded year
1891
Operating status
Operating
Headcount range
5,001–10,000 employees
Short description
Merck & Co., Inc. is a US-headquartered biopharmaceutical company that develops and commercializes prescription medicines and vaccines across oncology, vaccines, infectious diseases, immunology, cardiometabolic, and animal health, anchored by the Keytruda immuno-oncology franchise and a global multi-modality R&D engine.
Ownership category
akta.pro rank

Merck industry classification

Industry
Product category
Biopharmaceuticals
NAICS
Biological Product (except Diagnostic) Manufacturing (325414), Veterinary Services (54194), Veterinary Services (541940)
SIC
Biological Products, (No Disgnostic Substances) (2836), Wholesale-Drugs, Proprietaries & Druggists' Sundries (5122)
akta.pro primary industry
Veterinary Vaccines (Biologics) (HLAMAEAL)
akta.pro secondary industries
Veterinary Vaccines (HLAIAEAH), Livestock & Production Animal Therapeutics (Rx) (HLAMAEAB), Companion Animal Vaccines (Dogs & Cats) (HLAMAKAA), Livestock Vaccines (Cattle, Swine, Sheep & Goats) (HLAMAKAB)

Keywords

  • Biopharmaceutical medicines
  • Oncology therapies
  • Vaccines and prevention
  • Immuno-oncology drugs
  • Animal health products

Where Merck is headquartered

Location

Headquarters

HQ city
Rahway
HQ country
United States
HQ region
North America

Offices9 records

Markets served

Merck business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

  1. Pharmaceutical product sales (human health): Primary revenue stream from sales of patented prescription medicines and vaccines including Keytruda, Gardasil, Januvia, Keytruda Qlex, Welireg, Capvaxive, and a broad oncology, vaccines, infectious disease, and cardiometabolic/respiratory portfolio. Keytruda alone generated $8.0B in Q1 2026 (8% YoY growth) and $8.37B in Q4 2025. 2026 revenue guidance: $65.5-67.0B.
  2. Animal Health product sales: Merck Animal Health sells veterinary pharmaceuticals, vaccines, and health management solutions/digital products for livestock and companion animals (e.g., Bravecto). Operates as a separate global business unit with its own distribution network and 70+ year history.
  3. Collaboration and licensing income (incl. co-development milestone payments): Revenue from strategic co-development partnerships including Moderna (mRNA-4157), Gilead (islatravir/lenacapavir once-weekly HIV), Daiichi Sankyo (ADC programs), and Astellas (Padcev combination). Includes upfront payments, R&D milestones, and royalty/profit-share arrangements.
  4. Merck Medical Outreach Program (product donations): Charitable product donation program (65+ years) channeling pharmaceuticals and vaccines through qualified NGO partners (AmeriCares, CMMB, Direct Relief, MAP International, Partners In Health, Project HOPE) to low- and middle-income countries and disaster relief. Not a commercial revenue stream but tracked for impact metrics.
  5. Investment income (Impact Venture Fund): $55M+ of venture capital investments via Impact Venture Fund into funds/companies addressing health access in LMICs. Returns are recycled into new investments; impact reaches 35M+ people cumulatively since 2018.

Pricing tiers

ModelBillingPrice
Unit PricingPay-as-you-goNegotiated unit pricing with payers/governments; 3% dividend yield to shareholders; A+ credit rating.

Go-to-market motion4 records

Distribution channels6 records

Merck product offering

Product offering

Core offering

Merck is a global biopharmaceutical company that discovers, develops, manufactures, and commercializes prescription medicines and vaccines for human health, alongside veterinary pharmaceuticals, vaccines, and connected health technologies for animal health through its Merck Animal Health division. Its commercial portfolio is anchored by the KEYTRUDA immuno-oncology franchise and combination regimens, a broad vaccines portfolio (GARDASIL, CAPVAXIVE, ERVEBO, M-M-R, PNEUMOVAX, RECOMBIVAX HB), the Lagevrio COVID-19 antiviral, JANUVIA for Type 2 diabetes, tulisokibart for ulcerative colitis, and BRAVECTO and other parasiticide products for companion animals.

Product overview

Merck operates a multi-franchise biopharmaceutical portfolio rather than a single unified product, anchored by the KEYTRUDA immuno-oncology franchise — including the IV KEYTRUDA backbone, the subcutaneous KEYTRUDA QLEX co-formulation, and combination partners such as WELIREG, Padcev, Trodelvy, and Moderna's intismeran autogene (mRNA-4157). Its vaccines franchise spans GARDASIL (HPV), CAPVAXIVE (pneumococcal), ERVEBO (Ebola Zaire), M-M-R, PNEUMOVAX, and RECOMBIVAX HB, while infectious-disease and cardiometabolic franchises include Lagevrio for COVID-19 and JANUVIA for Type 2 diabetes. Animal Health is represented by BRAVECTO and is being expanded into biodevices via the announced TARGAN acquisition. Pipeline and acquired assets layered on top include tulisokibart (anti-TL1A, ex-Prometheus), TERN-701 (ex-Terns), CD388 (ex-Cidara), the islatravir + lenacapavir HIV combination with Gilead, and the personalized cancer vaccine program with Moderna. Underpinning this portfolio is M-Trust, Merck's physical authentication technology, which integrates with The Hashgraph Group's TrackTrace Digital Product Passport on the Hedera network to secure regulated pharmaceutical supply chains, and Merck's broader AI stack (TEDDY models, Prot-MaP via Protillion, and expanded AI partnerships) which supports discovery and translational research across the franchise.

Differentiator

Problem solved

Functional benefit

Brands

  • Merck Animal Health: Global animal health business unit offering veterinary pharmaceuticals, vaccines, and health management solutions for livestock and companion animals, with over 70 years of history.
  • Merck Foundation
  • Merck for Mothers

Products and services

  • KEYTRUDA (pembrolizumab) Merck's flagship anti-PD-1 checkpoint inhibitor, initially FDA approved in 2014 and used across more than two dozen tumor types as monotherapy and backbone of multiple combination regimens (with Padcev, WELIREG, Trodelvy, mRNA-4157). Q1 2026 sales of $8.0B; Q4 2025 sales of $8.37B.
  • KEYTRUDA QLEX (pembrolizumab and berahyaluronidase alfa-pmph) Subcutaneous co-formulation of pembrolizumab with the hyaluronidase enzyme berahyaluronidase alfa-pmph, designed to shorten administration time versus IV KEYTRUDA while preserving efficacy; approved alongside IV KEYTRUDA in combination regimens such as the first-line TNBC regimen with Trodelvy.
  • WELIREG (belzutifan) HIF-2α inhibitor approved in combination with KEYTRUDA for adjuvant and advanced renal cell carcinoma and used as the combination backbone in Merck's expanding RCC franchise. 41% sales growth to $716M in 2025; Leerink projects $3.4B by 2028.
  • Tulisokibart (MK-7240) Anti-TL1A monoclonal antibody acquired through Merck's Prometheus Biosciences transaction; reported positive Phase 3 results in moderate-to-severe ulcerative colitis in June 2026 (first anti-TL1A biologic to demonstrate Phase 3 UC clinical remission), positioning it as a late-stage immunology candidate being evaluated across 7 disease indications.
  • JANUVIA (sitagliptin) DPP-4 inhibitor for the treatment of Type 2 diabetes, one of Merck's established cardiometabolic franchises facing patent expiration contributing to the ~$2.5B 2026 generic/Medicare impact.
  • GARDASIL Merck's HPV vaccine, a foundational product in the vaccines franchise for the prevention of HPV-related cancers and diseases. Subject of Merck's Gardasil lawsuit settlement of approximately $50 million.
  • CAPVAXIVE Pneumococcal 21-valent Conjugate Vaccine; originally approved for adults and subsequently expanded by FDA to at-risk pediatric populations; covers ~79% of invasive pneumococcal disease serotypes in at-risk children.
  • ERVEBO Merck's Ebola Zaire vaccine, used as part of Merck's infectious-disease vaccines portfolio.
  • M-M-R (measles-mumps-rubella vaccine) Combination measles-mumps-rubella vaccine, a long-established Merck vaccine product.
  • PNEUMOVAX Pneumococcal polysaccharide vaccine for adult pneumococcal disease prevention.
  • RECOMBIVAX HB Merck's recombinant hepatitis B vaccine.
  • Lagevrio (molnupiravir) Oral antiviral authorized for the treatment of mild-to-moderate COVID-19 in at-risk adults; also being offered as a potential countermeasure in a WHO-led DRC Ebola trial.
  • BRAVECTO Flagship Merck Animal Health parasiticide brand for dogs and cats providing long-duration flea and tick protection.
  • TERN-701 Allosteric BCR-ABL inhibitor for chronic myeloid leukemia (CML), obtained through Merck's acquisition of Terns Pharmaceuticals and integrated into Merck's oncology pipeline.
  • CD388 Long-acting influenza prevention candidate acquired via the announced acquisition of Cidara Therapeutics, intended to anchor Merck's antiviral franchise.
  • Islatravir + lenacapavir (oral HIV combination) Once-weekly oral combination of Merck's islatravir (nucleoside reverse transcriptase translocation inhibitor) and Gilead's lenacapavir for heavily treatment-experienced adults with multidrug-resistant HIV-1; reported positive Phase 3 results in June 2026 and, if approved, would be the first long-acting oral HIV treatment taken once weekly.
  • Intismeran autogene (mRNA-4157 / V940) Personalized neoantigen mRNA cancer vaccine co-developed with Moderna, combined with KEYTRUDA in resected high-risk melanoma; Phase 2b KEYNOTE-942 five-year data showed 49% reduction in recurrence or death and 59% reduction in distant metastasis; 9 Phase 2/3 trials underway across melanoma, NSCLC, bladder cancer, and RCC.

Quantifiable outcome

  • 35% reduction in risk of disease progression or death with Keytruda + Trodelvy vs Keytruda + chemo in 1L PD-L1+ mTNBC (median PFS 11.2 vs 7.8 months)
  • +6 more outcomes

Companies that use Merck

Customer profile

Named customers10 records

Segments8 records

Ideal customer profiles4 records

Merck technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Integration2 records

AI capability10 records

Feature9 records

Merck partnerships and signals

Strategic signal

Partnerships

33 partnerships are on record, tiered flagship, core and minor.

  • Gilead SciencesflagshipStrategic or Co-development Partner · 24 June 2026Multiple co-development programs: (1) Trodelvy (sacituzumab govitecan-hziy) + Keytruda combination approved in 1L PD-L1+ metastatic TNBC (June 2026) and under EU review; (2) Once-weekly oral HIV treatment islatravir/lenacapavir met primary efficacy in Phase 3 ISLEND-1 and ISLEND-2; (3) Lung cancer combo trial KEYNOTE-D46/EVOKE-03 discontinued. Relationship is mutual co-development.
  • Astellas PharmaflagshipStrategic or Co-development Partner · 24 June 2026Co-promotion of Padcev (enfortumab vedotin) + Keytruda (pembrolizumab) combination as perioperative treatment for adults with resectable muscle-invasive bladder cancer who are ineligible for cisplatin. EU approval June 2026 based on Phase 3 KEYNOTE-905 showing 60% reduction in EFS events and 50% reduction in death risk vs surgery alone.
  • Daiichi SankyocoreStrategic or Co-development Partner · 24 June 2026Co-development of ADC programs including ifinatamab deruxtecan (B7-H3 ADC). Daiichi appointed John Tsai as head of R&D to execute 5-year plan to become a top-5 oncology company by 2035. Merck is referenced as a key ADC partner alongside AstraZeneca.
  • Mapp BiopharmaceuticalminorStrategic or Co-development Partner · 24 June 2026Merck is offering its antiviral molnupiravir (Lagevrio) as a potential countermeasure in a WHO-led DRC Ebola trial testing MBP134 and remdesivir against Bundibugyo ebolavirus. Outbreak has caused 1,094 confirmed cases and 277 deaths.
  • MaeminorGTM or Marketing Partner · 23 June 2026Multi-state partnership through Merck for Mothers initiative to expand and sustain the community-based doula workforce in California, Georgia, Illinois, and Texas. Provides doula training, professional development, and administrative support to help community doulas achieve Medicaid participation.
  • ExelixisminorStrategic or Co-development Partner · 22 June 2026Clinical development collaboration for the STELLAR-316 trial evaluating zanzalintinib combination in metastatic colorectal cancer.
  • Nectin TherapeuticsminorStrategic or Co-development Partner · 17 June 2026Clinical combination partnership evaluating NTX1088 (first-in-class anti-CD155 antibody) + Keytruda in 91 patients with advanced solid tumors; Phase 1a/1b data presented at ASCO 2026.
  • Protillion BiosciencescoreTechnology or Integration · 16 June 2026Multi-target drug discovery collaboration and license agreement. Merck gets access to Prot-MaP AI platform for designing biologic therapies across multiple undisclosed indications. Protillion eligible for up to $510M in R&D and commercial milestone payments.
  • Terns PharmaceuticalsflagshipStrategic or Co-development Partner · 15 June 2026Merck acquiring Terns Pharmaceuticals for approximately $6.7B (announced March 2026; ~$5.7B net of acquired cash; 31% premium to 60-day VWAP). Brings lead candidate TERN-701, an investigational oral allosteric BCR::ABL1 tyrosine kinase inhibitor in Phase 1/2 for chronic myeloid leukemia (FDA Orphan Drug Designation March 2024). Expected to close in Q2 2026.
  • RochecoreTechnology or Integration · 11 June 2026Companion diagnostic partnership: Roche's VENTANA MMR RxDx Panel received EU IVDR approval as a companion diagnostic for Keytruda (Merck) across 5 cancer types and 6 indications, alongside IMFINZI/LYNPARZA (AstraZeneca) and JEMPERLI (GSK). Validates patient selection for Keytruda therapy.
  • TarganminorStrategic or Co-development Partner · 11 June 2026Definitive agreement by Merck Animal Health to acquire Targan, a privately held company developing biodevice solutions for the poultry industry. Deal expected to close in Q3 2026 pending regulatory approvals.
  • Agilent TechnologiescoreTechnology or Integration · 2 June 2026Co-developed PD-L1 IHC 22C3 pharmDx companion diagnostic on Dako Omnis platform for Keytruda. FDA approved expansion to 4 additional cancer types (esophageal SCC, TNBC, cervical, gastric/GEJ adenocarcinoma), enabling consolidated PD-L1 testing across tumor types.
  • ModernaflagshipStrategic or Co-development Partner · 1 June 2026Co-development of intismeran autogene (mRNA-4157) individualized neoantigen therapy combined with Keytruda. 5-year Phase 2b KEYNOTE-942 data showed 49% reduction in melanoma recurrence/death and 59% reduction in distant metastasis. 9 total Phase 2/3 trials underway across melanoma, NSCLC, bladder cancer, and renal cell carcinoma. Phase 3 INTerpath trial ongoing.
  • Kelun-BiotechcoreStrategic or Co-development Partner · 1 June 2026Co-developer of sacituzumab tirumotecan (sac-TMT) TROP2-directed antibody-drug conjugate. Phase 3 data in 1L NSCLC showed 80.4% 1-year OS with sac-TMT+Keytruda vs 68.9% for Keytruda monotherapy; 70% ORR; 65% reduced tumor progression risk. Phase 3 TroFuse-005 in endometrial cancer met OS and PFS endpoints.
  • City Cancer ChallengecoreGTM or Marketing Partner · 15 May 2026Expanded global partnership to strengthen women's cancer care. Initiative aims to reach more than 300,000 women living with cancer around the world by 2030.
  • Cidara TherapeuticsflagshipStrategic or Co-development Partner · 14 November 2025Merck agreed to acquire Cidara Therapeutics for approximately $9.2B to develop CD388, a long-acting antiviral drug for influenza prevention (Phase III). Part of Merck's strategy to diversify beyond Keytruda's patent cliff.
  • Imago BioSciencescoreStrategic or Co-development Partner · 22 November 2022Merck acquired Imago BioSciences for approximately $1.35B in all-cash deal (closed Q1 2023) to strengthen pipeline in hematology through development of medicines for myeloproliferative neoplasms (MPNs) and other bone marrow diseases.
  • AmeriCarescoreOthersQualified NGO partner receiving Merck pharmaceutical and vaccine donations through the Merck Medical Outreach Program (65+ years) for humanitarian assistance in LMICs and disaster relief worldwide.
  • Direct ReliefcoreOthersQualified NGO partner in the Merck Medical Outreach Program receiving pharmaceutical and vaccine donations for humanitarian use in LMICs.
  • Partners In HealthcoreOthersQualified NGO partner receiving Merck Medical Outreach Program donations of medicines and vaccines for humanitarian programs in low- and middle-income countries.
  • Project HOPEcoreOthersQualified NGO partner in Merck's Medical Outreach Program; receives pharmaceutical and vaccine donations for distribution in LMICs and disaster relief.
  • MAP InternationalcoreOthersQualified NGO partner in Merck's Medical Outreach Program receiving pharmaceutical donations for distribution in low- and middle-income countries.
  • CMMB (Catholic Medical Mission Board)coreOthersQualified NGO partner receiving Merck Medical Outreach Program donations of pharmaceuticals and vaccines for humanitarian assistance in developing countries.
  • UNICEF USminorOthersImpact investing partnership supporting acceleration of critical health care commodities for vulnerable children in limited-resource settings.
  • Tempus AIcoreTechnology or IntegrationData partnership with AI-enabled precision medicine company. Leverages 45M+ de-identified patient records and 500+ petabytes of data. Individual deal values reaching up to $320M. AstraZeneca and GSK also cited as Tempus partners.
  • Prometheus BiosciencesflagshipStrategic or Co-development PartnerAcquired by Merck for $10.8-11B in 2023. Lead program tulisokibart (MK-7240), an anti-TL1A monoclonal antibody, met primary endpoint of clinical remission at week 12 in Phase 3 ATLAS-UC induction-only study for ulcerative colitis - first anti-TL1A biologic to achieve this milestone. Being evaluated across 7 disease indications.
  • N.C. A&T (North Carolina Agricultural and Technical State University)minorStrategic or Co-development PartnerPartnership to launch a collaborative biotechnology learning center as a foundation for future talent development.
  • PfizercoreStrategic or Co-development PartnerPfizer is continuing a late-stage study testing sigvotatug vedotin in combination with Merck's Keytruda as a first-line treatment for NSCLC. Combinatorial use of Keytruda as backbone in lung cancer studies.
  • Ukko LaboratoriesminorStrategic or Co-development PartnerCooperation agreement covering Ukko's RNA-based peanut allergy therapy (Ukko18) and Aulos Bioscience's AI-designed cancer immunotherapy. Ukko and Aulos Biolojic Design have raised over $200M for research combined.
  • Google CloudcoreTechnology or Integration$1B partnership with Google Cloud for AI infrastructure, referenced alongside Merck's broader AI agenda including the Protillion Biosciences AI drug discovery collaboration.
  • Questex / Fierce Life Sciences (Partnerships with Sites Summit)minorGTM or Marketing PartnerMerck executives participating in the 2nd annual Partnerships with Sites Summit (September 14, 2026, Boston), alongside Eli Lilly, Biogen, Novartis, AstraZeneca, Sanofi, and Takeda to address clinical trial system challenges costing the industry ~$50B annually.
  • AMR Action FundcoreStrategic or Co-development PartnerMerck committed $100M over 10 years to the AMR Action Fund, a partnership of 20+ leading pharmaceutical companies, philanthropies, and organizations aimed at bringing 2-4 novel antibiotics to patients and physicians by 2030.
  • Gilead Sciences (HIV clinical collaboration)flagshipStrategic or Co-development PartnerClinical trials for HIV treatment involving islatravir/lenacapavir (once-weekly oral HIV treatment) - if approved, would be the first long-acting oral HIV treatment taken once weekly. Per Cantor Fitzgerald, positive outcomes were observed.

Scale indicators15 records

Recent moves6 records

Expansion highlights4 records

Merck competitors and assessment

Company assessment

Direct peers

  • Bristol Myers Squibb: Direct PD-1/PD-L1 oncology competitor with Opdivo (nivolumab) competing head-to-head with Keytruda across multiple tumor types. Similar large-cap biopharma profile with comparable oncology, immunology, and cardiovascular franchises.
  • Roche: Direct oncology competitor with Tecentriq (PD-L1) plus deep companion diagnostic footprint. Roche's VENTANA MMR RxDx Panel is a CDx for Keytruda, illustrating the intertwined competitive and partnership dynamics across immuno-oncology.
  • AstraZeneca: Direct PD-L1 competitor (Imfinzi/durvalumab) and ADC platform partner alongside Daiichi Sankyo. Competes with Merck in lung, breast, and GI oncology while sharing the ADC modality frontier.

Broad incumbents

  • Pfizer: Comparable large-cap biopharma with overlapping oncology, vaccines, and infectious disease franchises. Currently combining its sigvotatug vedotin with Merck's Keytruda in NSCLC trials, illustrating both competitive overlap and partnership dynamics.
  • Eli Lilly: Similar large-cap biopharma competing across oncology, immunology, cardiometabolic, and neuroscience. Lilly's tirzepatide/Verona-style acquisition strategy and oncology pipeline expansion parallel Merck's M&A-driven approach.
  • Novartis: Comparable global biopharma with strong oncology (Pluvicto, Kisqali), cardiovascular, and immunology franchises. Competes directly in radioligand therapy and CDK4/6 inhibitor spaces adjacent to Merck's oncology pipeline.
  • Johnson & Johnson: Diversified large-cap with a sizable Innovative Medicine pharmaceutical segment overlapping Merck's oncology, immunology, and infectious disease franchises. J&J's Darzalex and oncology pipeline compete for the same oncologists and indications.
  • AbbVie: Comparable large-cap biopharma that has navigated a major Humira patent cliff via Skyrizi/Rinvoq and aggressive M&A (Allergan, ImmunoGen, Cerevel). Provides a useful precedent for managing large patent-cliff transitions.
  • Sanofi: Global biopharma with overlapping immunology (Dupixent), vaccines, and rare disease franchises. Competes with Merck in inflammatory bowel disease and is an established vaccines peer.
  • GSK: Direct competitor in vaccines (Shingrix, HPV, pneumococcal), HIV (ViiV Healthcare), and oncology (Jemperli PD-1 inhibitor). GSK's oncology pipeline competes with Merck in endometrial and other gynecologic cancers.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat7 records

Key risks7 records

Key highlights7 records

Customer concentration

Merck social profiles

Digital presence

Merck financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Merck leadership team

Management profile

Number of profiles

Profiles27 records

Merck subsidiaries and ownership

Company hierarchy

Subsidiaries6 records

Merck funding detail

Funding detail

Funding overview

Funding rounds2 records

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Merck M&A and investment

M&A and investment

M&A42 records

Investments35 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Merck

What does Merck do?

Merck is a global biopharmaceutical company that discovers, develops, manufactures, and commercializes prescription medicines and vaccines for human health, alongside veterinary pharmaceuticals, vaccines, and connected health technologies for animal health through its Merck Animal Health division. Its commercial portfolio is anchored by the KEYTRUDA immuno-oncology franchise and combination regimens, a broad vaccines portfolio (GARDASIL, CAPVAXIVE, ERVEBO, M-M-R, PNEUMOVAX, RECOMBIVAX HB), the Lagevrio COVID-19 antiviral, JANUVIA for Type 2 diabetes, tulisokibart for ulcerative colitis, and BRAVECTO and other parasiticide products for companion animals.

Is Merck a public or private company?

Merck is a public company. It is classified as public and is currently operating.

When was Merck founded?

Merck was founded in 1891. It employs 5,001 to 10,000 people.

Where is Merck based?

Merck is headquartered in Rahway, United States, in the North America region.

How does Merck make money?

Five revenue lines are on record. Pharmaceutical product sales (human health) is the primary driver. The others are animal Health product sales, collaboration and licensing income (incl. co-development milestone payments), merck Medical Outreach Program (product donations) and investment income (Impact Venture Fund).

Who are Merck's main competitors?

Direct peers on record are Bristol Myers Squibb, Roche and AstraZeneca. Broad incumbents are Pfizer, Eli Lilly, Novartis, Johnson & Johnson, AbbVie, Sanofi and GSK.

Does Merck have an API?

No public API is recorded for Merck.

What industry is Merck in?

Merck's product category is Biopharmaceuticals. Its primary akta.pro industry code is HLAMAEAL, Veterinary Vaccines (Biologics), with a secondary code of HLAIAEAH, Veterinary Vaccines. Its NAICS code is 325414 and its SIC code is 2836.

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Live signals
MarketScreenerHalozyme Wins Injunction Against Merck in Keytruda Patent Case -- UpdateA Dutch court granted Halozyme an injunction against Merck, barring the company from manufacturing and distributing Keytruda SC in Belgium, Denmark, France, Ireland, Italy, Sweden, Switzerland, and the Netherlands. Merck disputes the ruling, calling the patent invalid, while Halozyme says patients can still access the IV version.MorningstarHalozyme Wins Injunction Against Merck in Keytruda Patent Case — UpdateA Dutch court granted Halozyme an injunction against Merck, barring the company from manufacturing and distributing Keytruda SC in Belgium, Denmark, France, Ireland, Italy, Sweden, Switzerland, and the Netherlands. Merck disputes the ruling, calling the patent invalid, while Halozyme notes patients can still access the IV version of the drug.Investing.comHalozyme stock rises after winning injunction against MerckHalozyme Therapeutics shares rose 2% after a Dutch court ruled Merck infringed its MDASE patent and ordered MSD to halt Keytruda SC in multiple European markets. The injunction also rejected Merck's invalidity arguments, and Halozyme has filed a U.S. lawsuit against Merck.STATMerck suffers a setback in Europe over its new Keytruda formulationA Dutch court ruled Merck infringed a patent on its subcutaneous Keytruda formulation and ordered it to halt manufacturing and marketing in several European countries, including France, Italy, Sweden, Switzerland, and the Netherlands. The ruling is part of a patent dispute with Halozyme Therapeutics, and patients can still access the existing intravenous version.Quiver Quantitative24/7 Market News Highlights NeOnc, Revolution Medicines, Moderna, Merck, Johnson & Johnson and Genmab, AbbVie in 2026 Cancer Treatment Advances | NTHI Stock News24/7 Market News reported 2026 cancer treatment advances, including NeOnc's Phase 2a data showing a median overall survival of 26.09 months for recurrent brain cancer with NEO100, and Revolution Medicines' FDA-approved Rasonque extending pancreatic cancer survival to 13.2 months versus 6.7 months. Moderna and Merck also reported positive Phase 3 results for personalized mRNA therapy.MarketScreenerHalozyme Granted Another Injunction Against Merck in Keytruda Patent CaseA Dutch court granted Halozyme an injunction against Merck, halting the launch of Keytruda SC in Belgium, Denmark, France, Ireland, Italy, Sweden, Switzerland, and the Netherlands. The court rejected Merck's invalidity arguments, and patients can still access the IV version of the drug.MorningstarHalozyme Granted Another Injunction Against Merck in Keytruda Patent CaseA Dutch court granted Halozyme an injunction against Merck, halting the launch of Keytruda SC in Belgium, Denmark, France, Ireland, Italy, Sweden, Switzerland, and the Netherlands. The court rejected Merck's invalidity arguments, and patients can still access the IV version of the drug.ReutersHalozyme wins court order to block Merck's injected Keytruda in select European marketsA Dutch court ruled Merck infringed Halozyme's MDASE patent, ordering it to stop producing and selling injectable Keytruda in Belgium, Denmark, France, Ireland, Italy, Sweden, Switzerland, and the Netherlands. Halozyme also sued Merck in the US and Germany, where a preliminary injunction was granted last year.MarketScreenerTempus Enters Multiyear Collaboration With Moderna, Merck Aimed at Commercializing Cancer DrugTempus announced a multiyear collaboration with Moderna and Merck to support the commercialization of intismeran autogene, a cancer therapy evaluated with Merck's Keytruda. Tempus will manage tumor tissue and blood sample collection for next-generation sequencing, expanding work started last year.Seeking AlphaMerck’s injectable Keytruda barred in Europe (MRK:NYSE)A Dutch court barred Merck from marketing injectable Keytruda in Belgium, Denmark, France, Ireland, Italy, Sweden, Switzerland, and the Netherlands, citing patent infringement by Halozyme. The injunction does not affect intravenous Keytruda, and Halozyme has launched a global enforcement campaign.