What Coyote Ventures does

Coyote Ventures is a Delaware-registered venture capital firm headquartered in San Francisco, founded in 2021 by Jessica Karr (formerly the 12th employee at Impossible Foods). The firm operates as a pre-seed and seed-stage investor focused on health equity and women's health, deploying capital into tech-enabled solutions that address access gaps for women and historically marginalized communities. Its stated thesis is organized around five pillars: Human Health & Lifespan, Social & Structural Health, Whole-Person Health, Systems & Infrastructure, and Science & Frontier Technology. As of the 2025 Impact Report, the portfolio comprises 19 companies spanning maternal health (Millie, Hey Malama), sexual wellness (Maude, Flex), menopause (Wile), oncology diagnostics (Gabbi, Hera Biotech), fertility financing (Sunfish), bereavement (Betterleave), caregiving (Magnolia), SDOH data (Alvee), payer analytics (Lilac Software), care decision support (Koda Health), parental leave benefits (ParentOleave), culturally competent nutrition (Pom Health), financial wellness for care workers (The Beans), and parent community (Auggie).

The firm does not develop proprietary technology products; its intellectual property is its investment thesis framework, its structured impact measurement methodology, and its network of healthcare executives, doctors, scientists, payers, and policymakers. Coyote raises capital from institutional Limited Partners (with Bank of America as the largest LP in Fund I, alongside The Case for Her and Tripple Family Office) and generates revenue through the standard VC model of management fees (typically ~2% of committed capital) and carried interest (typically ~20% of profits above the hurdle) on portfolio exits. Distribution and sourcing channels include direct outreach, warm introductions, participation in Y Combinator and Vive Collective, and biannual Health Equity Innovators Summit events. The firm is led by General Partner Jessica Karr, supported by a three-person Investment Committee and seven Venture Partners drawn from Adobe, Google, Kaiser Permanente, Mercer, UnitedHealthcare/Optum, Delfina, and Oak Street Health.

Name

Coyote Ventures

Legal name

Coyote Ventures

Website

https://coyote.ventures

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

1–10 employees

Short description

Coyote Ventures is a San Francisco-based pre-seed and seed venture capital firm founded in 2021 by Jessica Karr that invests in tech-enabled health equity and women's health startups, managing a portfolio of 19 companies with Bank of America as its largest Fund I institutional LP.

Ownership category

akta.pro rank

Product category

Venture Capital / Healthcare Investment

NAICS

Portfolio Management and Investment Advice (523940), Portfolio Management and Investment Advice (52394)

SIC

Investment Advice (6282)

akta.pro primary industry

Early-Stage Venture Capital (Pre-Seed/Seed) (FSANAAAA)

akta.pro secondary industries

Healthcare Access & Life Sciences Impact Funds (FSANAJAI), Impact Investing & Social Finance (Funds, CDFIs, Microfinance) (BPAGALAA)

Keywords

• Venture capital investing
• Health equity investing
• Pre-seed funding
• Seed-stage investing
• Women's health ventures

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Others

Revenue model

1. Fund Management: Venture capital fund generating returns through management fees (typically 2% of committed capital) and carried interest (typically 20% of profits above the hurdle rate). Returns realized through portfolio company exits via acquisition, IPO, or secondary sales.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels7 records

Core offering

Coyote Ventures manages a pre-seed and seed-stage venture capital fund (Fund I) that invests in tech-enabled health equity companies serving women and historically marginalized populations, while providing portfolio founders with capital, strategic guidance, network access, and biannual Health Equity Innovators Summit programming. The firm earns returns through standard venture fund economics of management fees and carried interest, sourced from a portfolio of 19 companies spanning maternal health, sexual wellness, breast cancer risk, endometriosis, bereavement, fertility financing, caregiver support, SDOH data, payer analytics, and financial wellness for care workers.

Product overview

Coyote Ventures is a pre-seed and seed-stage venture capital firm founded in 2021 that invests in tech-enabled solutions driving healthcare access for overlooked populations, with a focus on women and historically marginalized communities. The firm's portfolio comprises 19 companies spanning multiple health equity verticals including maternal health (Hey Malama, Millie), sexual wellness (Maude), menopause and perimenopause (Wile), breast cancer risk assessment (Gabbi), endometriosis diagnostics (Hera Biotech), period care (Flex Company), bereavement support (Betterleave), caregiver support (Magnolia), fertility financing (Sunfish), SDOH data management (Alvee), payer analytics (Lilac Software), healthcare decision support (Koda Health), parental leave benefits (ParentOleave), nutrition care (Pom Health), financial wellness for care workers (The Beans), and general parenting (Auggie). The fund does not offer its own product or service; its investment activity and portfolio companies constitute its business.

Differentiator

Problem solved

Functional benefit

Products and services

• Coyote Ventures Fund I Pre-seed and seed-stage venture capital fund that invests in tech-enabled health equity companies serving women and historically marginalized populations, with returns generated through management fees and carried interest on portfolio exits. The fund provides portfolio companies with capital, strategic guidance, network access to healthcare executives and payers, and biannual Health Equity Innovators Summit programming.

Quantifiable outcome

• 95% of portfolio companies are female-led with 57% of co-founders identifying as BIPOC
• +2 more outcomes

Named customers20 records

Segments2 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

Two partnerships are on record, tiered minor and core.

• Transact GlobalminorGTM or Marketing PartnerGroup of female general partners through which Coyote was introduced to portfolio company Betterleave.
• Healthequityinnovators.comcoreStrategic or Co-development PartnerDedicated platform for the Health Equity Innovators Summit, a core community-building and networking initiative for the health equity ecosystem.

Scale indicators8 records

Recent moves6 records

Expansion highlights5 records

Market position

Strengths4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/Coyote_Ventures
• LinkedInlinkedin.com/company/coyoteventures

Revenue estimate

Valuation estimate

Number of profiles

Profiles12 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments16 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Coyote Ventures