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Vial

Full company profile

uuid00007m6

Namestring
Vial
Legal namestring
Vial Health Technology, Inc.
Websiteurl
vial.com
Company typeenum
Private
Founded yearint
2020
Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
101–250
akta.pro rankint
HeadquartersSan Francisco, United States
HQ citystring
San Francisco
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Offices2 records

Each record includes

City, Country, Type, Description, Source

Keyword5 values
biologics development, RNA therapeutics, clinical trial platform, bispecific antibodies, drug discovery
Industry3 codes
1Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering)
CodeHLAAAIABPrimaryYes
2Clinical Development (Phase I–III Trial Design & Execution)
CodeHLAIALAEPrimaryNo
3Cell-Based & Potency Assays (Bioassays)
CodeHLAGADAHPrimaryNo
NAICS code3 codes
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
  • Biological Product (except Diagnostic) Manufacturing325414
  • Pharmaceutical and Medicine Manufacturing3254
SIC code3 codes
  • Biological Products, (No Disgnostic Substances)2836
  • Pharmaceutical Preparations2834
  • Services-Commercial Physical & Biological Research8731
Product category
Biopharmaceuticals
Social media profiles3 records
GTM motion2 records

Each record includes

Type, Description, Source

Revenue model2 records
1Licensing Deals
TypeLicensing Royalties
Description

Vial licenses its wholly owned assets in Oncology, Ophthalmology, Immunology & Inflammation, Cardiometabolic, and Rare Diseases to pharmaceutical partners. These are primarily antibody (mAb, TCE, bsAb) and RNA treatments (siRNA, ASO). Revenue is generated through upfront payments, milestone payments, and royalties from licensing agreements.

vial.com
2Clinical Development Services
TypeProfessional Services
Description

Vial leverages its vertically integrated Phase I clinic in Australia and proprietary clinical trial platform to conduct clinical trials, which may generate revenue through partnerships with biotech sponsors.

vial.com
Marketing channels5 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels1 record

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components5 values
Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure
GTM typeB2B
B2B
Offering typeServices
Services
Core offering1 text field

Vial is a clinical-stage biotechnology company that designs and develops first and best-in-class biologics and RNA therapeutics focused on Immunology & Inflammation, including a half-life-extended IL-13 x TSLP bispecific antibody for asthma and an INHBE siRNA therapy for obesity. The company combines AI-enabled target discovery, iterative molecule design, and high-throughput experimental validation with a vertically integrated Phase I clinical trial operation in Australia, and commercializes its pipeline assets through licensing and partnership deals with pharmaceutical sponsors.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 7 values shown
  • Phase I clinic costs 80%+ cheaper than typical clinical trial operations
+6 more records
Product overview1 text field

Vial is a clinical-stage biotechnology company advancing first and best-in-class biologics and RNA therapeutics in Immunology & Inflammation. The company's portfolio includes two core pipeline programs: IL-13 x TSLP (a half-life-extended bispecific antibody in Phase 1 for asthma and atopic dermatitis) and INHBE siRNA (a liver-targeted obesity therapy in Phase 1). Vial's technology platform enables automated clinical trials with vertical integration including a proprietary Phase I clinic in Australia, computational therapeutic design, and high-throughput experimental validation capabilities.

Product and service3 records
1IL-13 x TSLP (VIAL-IL13xTSLP)
CategoryBispecific Antibody Therapeutic
Description

A half-life-extended bispecific antibody targeting IL-13 and TSLP for the treatment of mild-to-moderate asthma, atopic dermatitis, and chronic sinusitis. Engineered for quarterly-to-biannual dosing with picomolar binding affinities for both targets, offered to pharmaceutical partners for licensing.

2INHBE (VIAL-INHBE) siRNA
CategoryRNA Therapeutic
Description

A liver-targeted siRNA therapy designed to block Activin E signaling and increase lipolysis for fat-selective weight loss while preserving muscle mass. Evaluated for obesity and cardiometabolic diseases, with potential use alone or in combination with GLP-1 therapies, offered to pharmaceutical partners for licensing.

3Clinical Trial Platform
CategoryClinical Trial Technology Platform
Description

Vial's proprietary technology platform that powers automated clinical trials with vertical integration, scale, and technology, leveraging a Phase I clinic in Australia to deliver Phase I clinical trials at 80%+ lower cost than typical operations and automated trial processes with 90%+ cost savings.

Scale indicator5 records

Each record includes

Type, Value, Description, Source

Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
TypeEmerging player
Description

Clinical-stage antibody engineering biotech with platform-based discovery capabilities. Comparable antibody engineering focus and similar clinical-stage size profile to Vial.

TypeDirect peer
Description

Clinical-stage biotech combining AI-driven target discovery with high-throughput experimental validation, very similar in approach to Vial. Both are platform-driven biotechs leveraging computation to compress drug development timelines.

TypeDirect peer
Description

AI-first biologics company using generative models to design novel antibody and protein therapeutics. Directly comparable to Vial's AI-designed biologics approach, including bispecific antibody design.

TypeDirect peer
Description

Antibody discovery and engineering platform with AI-augmented screening capabilities. Comparable to Vial's bispecific antibody engineering work, though AbCellera is a more mature platform business.

TypeDirect peer
Description

Machine learning-driven drug discovery company developing therapeutics for metabolic and neurological diseases. Comparable AI-driven discovery and validation methodology to Vial, with similar clinical-stage profile.

TypeDirect peer
Description

Computational drug design platform combining physics-based simulation with AI/ML for molecule design. Comparable technology stack to Vial's AI-driven molecule design, and serves a similar biotech customer base.

TypeEmerging player
Description

Clinical-stage biotech developing TSLP-targeting antibodies for inflammatory diseases. Directly comparable therapeutic target overlap with Vial's IL-13 x TSLP program and similar immunology-and-inflammation focus.

TypeEmerging player
Description

Clinical-stage biotech developing therapeutics for metabolic diseases including obesity, leveraging platform discovery. Directly comparable to VIAL-INHBE in obesity mechanism and cardiometabolic focus.

TypeEmerging player
Description

Clinical-stage oncology biotech with multiple pipeline programs and similar employee scale (~50–100) and venture-backed profile. Comparable size and clinical-stage structure, though focused on oncology rather than immunology.

TypeEmerging player
Description

Clinical-stage biotech operating a portfolio of asset-centric programs across multiple therapeutic areas. Comparable portfolio model and licensing approach to Vial, with similar stage and capital profile.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat5 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment2 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile1 record

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI capability2 records

Each record includes

Type, Description, Source

AI maturity
App detail

Has app

Feature8 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles13 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds4 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors5 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Vial

Biopharmaceuticalsvial.com

Vial firmographics

Firmographics
Name
Vial
Legal name
Vial Health Technology, Inc.
Website
https://vial.com
Company type
Private
Founded year
2020
Operating status
Operating
Headcount range
101–250 employees
Ownership category
akta.pro rank

Vial industry classification

Industry
Product category
Biopharmaceuticals
NAICS
Research and Development in Biotechnology (except Nanobiotechnology) (541714), Biological Product (except Diagnostic) Manufacturing (325414), Pharmaceutical and Medicine Manufacturing (3254)
SIC
Biological Products, (No Disgnostic Substances) (2836), Pharmaceutical Preparations (2834), Services-Commercial Physical & Biological Research (8731)
akta.pro primary industry
Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering) (HLAAAIAB)
akta.pro secondary industries
Clinical Development (Phase I–III Trial Design & Execution) (HLAIALAE), Cell-Based & Potency Assays (Bioassays) (HLAGADAH)

Keywords

  • Biologics development
  • RNA therapeutics
  • Clinical trial platform
  • Bispecific antibodies
  • Drug discovery

Where Vial is headquartered

Location

Headquarters

HQ city
San Francisco
HQ country
United States
HQ region
North America

Offices2 records

Markets served

Vial business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

  1. Licensing Deals: Vial licenses its wholly owned assets in Oncology, Ophthalmology, Immunology & Inflammation, Cardiometabolic, and Rare Diseases to pharmaceutical partners. These are primarily antibody (mAb, TCE, bsAb) and RNA treatments (siRNA, ASO). Revenue is generated through upfront payments, milestone payments, and royalties from licensing agreements.
  2. Clinical Development Services: Vial leverages its vertically integrated Phase I clinic in Australia and proprietary clinical trial platform to conduct clinical trials, which may generate revenue through partnerships with biotech sponsors.

Go-to-market motion2 records

Distribution channels1 record

Marketing channels5 records

Vial product offering

Product offering

Core offering

Vial is a clinical-stage biotechnology company that designs and develops first and best-in-class biologics and RNA therapeutics focused on Immunology & Inflammation, including a half-life-extended IL-13 x TSLP bispecific antibody for asthma and an INHBE siRNA therapy for obesity. The company combines AI-enabled target discovery, iterative molecule design, and high-throughput experimental validation with a vertically integrated Phase I clinical trial operation in Australia, and commercializes its pipeline assets through licensing and partnership deals with pharmaceutical sponsors.

Product overview

Vial is a clinical-stage biotechnology company advancing first and best-in-class biologics and RNA therapeutics in Immunology & Inflammation. The company's portfolio includes two core pipeline programs: IL-13 x TSLP (a half-life-extended bispecific antibody in Phase 1 for asthma and atopic dermatitis) and INHBE siRNA (a liver-targeted obesity therapy in Phase 1). Vial's technology platform enables automated clinical trials with vertical integration including a proprietary Phase I clinic in Australia, computational therapeutic design, and high-throughput experimental validation capabilities.

Differentiator

Problem solved

Functional benefit

Products and services

  • IL-13 x TSLP (VIAL-IL13xTSLP) A half-life-extended bispecific antibody targeting IL-13 and TSLP for the treatment of mild-to-moderate asthma, atopic dermatitis, and chronic sinusitis. Engineered for quarterly-to-biannual dosing with picomolar binding affinities for both targets, offered to pharmaceutical partners for licensing.
  • INHBE (VIAL-INHBE) siRNA A liver-targeted siRNA therapy designed to block Activin E signaling and increase lipolysis for fat-selective weight loss while preserving muscle mass. Evaluated for obesity and cardiometabolic diseases, with potential use alone or in combination with GLP-1 therapies, offered to pharmaceutical partners for licensing.
  • Clinical Trial Platform Vial's proprietary technology platform that powers automated clinical trials with vertical integration, scale, and technology, leveraging a Phase I clinic in Australia to deliver Phase I clinical trials at 80%+ lower cost than typical operations and automated trial processes with 90%+ cost savings.

Quantifiable outcome

  • Phase I clinic costs 80%+ cheaper than typical clinical trial operations
  • +6 more outcomes

Companies that use Vial

Customer profile

Segments2 records

Ideal customer profiles1 record

Vial technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

AI capability2 records

Feature8 records

Vial partnerships and signals

Strategic signal

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Vial competitors and assessment

Company assessment

Emerging players

  • Adagene: Clinical-stage antibody engineering biotech with platform-based discovery capabilities. Comparable antibody engineering focus and similar clinical-stage size profile to Vial.
  • Upstream Bio: Clinical-stage biotech developing TSLP-targeting antibodies for inflammatory diseases. Directly comparable therapeutic target overlap with Vial's IL-13 x TSLP program and similar immunology-and-inflammation focus.
  • BioAge Labs: Clinical-stage biotech developing therapeutics for metabolic diseases including obesity, leveraging platform discovery. Directly comparable to VIAL-INHBE in obesity mechanism and cardiometabolic focus.
  • Erasca: Clinical-stage oncology biotech with multiple pipeline programs and similar employee scale (~50–100) and venture-backed profile. Comparable size and clinical-stage structure, though focused on oncology rather than immunology.
  • Centessa Pharmaceuticals: Clinical-stage biotech operating a portfolio of asset-centric programs across multiple therapeutic areas. Comparable portfolio model and licensing approach to Vial, with similar stage and capital profile.

Direct peers

  • Recursion Pharmaceuticals: Clinical-stage biotech combining AI-driven target discovery with high-throughput experimental validation, very similar in approach to Vial. Both are platform-driven biotechs leveraging computation to compress drug development timelines.
  • Generate Biomedicines: AI-first biologics company using generative models to design novel antibody and protein therapeutics. Directly comparable to Vial's AI-designed biologics approach, including bispecific antibody design.
  • AbCellera Biologics: Antibody discovery and engineering platform with AI-augmented screening capabilities. Comparable to Vial's bispecific antibody engineering work, though AbCellera is a more mature platform business.
  • Insitro: Machine learning-driven drug discovery company developing therapeutics for metabolic and neurological diseases. Comparable AI-driven discovery and validation methodology to Vial, with similar clinical-stage profile.
  • Schrödinger: Computational drug design platform combining physics-based simulation with AI/ML for molecule design. Comparable technology stack to Vial's AI-driven molecule design, and serves a similar biotech customer base.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

Vial social profiles

Digital presence

Vial financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Vial leadership team

Management profile

Number of profiles

Profiles13 records

Vial funding detail

Funding detail

Funding overview

Funding rounds4 records

Investors5 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Vial M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Vial

What does Vial do?

Vial is a clinical-stage biotechnology company that designs and develops first and best-in-class biologics and RNA therapeutics focused on Immunology & Inflammation, including a half-life-extended IL-13 x TSLP bispecific antibody for asthma and an INHBE siRNA therapy for obesity. The company combines AI-enabled target discovery, iterative molecule design, and high-throughput experimental validation with a vertically integrated Phase I clinical trial operation in Australia, and commercializes its pipeline assets through licensing and partnership deals with pharmaceutical sponsors.

Is Vial a public or private company?

Vial is a private company. It is classified as venture growth investor backed and is currently operating.

When was Vial founded?

Vial was founded in 2020. It employs 101 to 250 people.

Where is Vial based?

Vial is headquartered in San Francisco, United States, in the North America region.

How does Vial make money?

Two revenue lines are on record. Licensing Deals are the primary driver. The others are clinical Development Services.

Who are Vial's main competitors?

Emerging players on record are Adagene, Upstream Bio, BioAge Labs, Erasca and Centessa Pharmaceuticals. Direct peers are Recursion Pharmaceuticals, Generate Biomedicines, AbCellera Biologics, Insitro and Schrödinger.

Does Vial have an API?

No public API is recorded for Vial.

What industry is Vial in?

Vial's product category is Biopharmaceuticals. Its primary akta.pro industry code is HLAAAIAB, Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering), with a secondary code of HLAIALAE, Clinical Development (Phase I–III Trial Design & Execution). Its NAICS code is 541714 and its SIC code is 2836.

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Live signals
YahooFirst patient dosed in Vial’s Phase Ib trial of IL-13 x TSLP antibodyVial dosed the first patient in its Phase Ib trial of an IL-13 x TSLP bispecific antibody for mild-to-moderate asthma. The study is placebo-controlled, double-blind, and randomised, with primary objectives of safety and tolerability. Data will guide dose and dosing-interval selection for future asthma treatment.PR NewswireVial Doses First Patient with Asthma in Phase 1b Study of Vial's IL-13 x TSLP, a Bispecific Antibody Designed for Twice-Yearly DosingVial dosed the first patient in its Phase 1b study of IL-13 x TSLP for mild-to-moderate asthma, following Phase 1a data in healthy volunteers. The study will assess safety, tolerability, pharmacokinetics, and FeNO-based proof-of-mechanism, with interim data expected in H1 2027.LinkedInLinkedInVial, a healthcare company, posted on LinkedIn highlighting limitations of GLP-1-based obesity therapies, including high dropout rates, heterogenous responses, and intolerable side effects. The company used these findings to promote its INHBE siRNA program as a more targeted and tolerable alternative treatment for obesity. Vial also announced its attendance at the 44th Annual J.P. Morgan Healthcare Conference in San Francisco.BioSpaceVial Doses First Patient for Phase 1 Trial of Vial’s IL-13 x TSLP, a Novel Bispecific AntibodyVial, a clinical-stage biotechnology company headquartered in San Francisco, announced on March 3, 2026 that it has dosed the first patient in a Phase 1 clinical trial in Australia for its IL-13 x TSLP bispecific antibody, a novel therapeutic candidate for mild-to-moderate asthma. The bispecific antibody employs half-life extension technology designed to enable quarterly-to-biannual dosing and demonstrated picomolar binding affinities with near-complete inhibition of the CCL17 pharmacodynamic marker in preclinical studies. Interim Phase 1 data readout is expected in H1 2026, with the trial enrolling healthy volunteers and patients to evaluate safety, tolerability, pharmacokinetics, and proof-of-mechanism.PR NewswireThe Next Chapter in Obesity Therapeutics: Vial's INHBE siRNA Draws KOL Praise as a Next-Generation Obesity TherapyVial announced growing enthusiasm among key opinion leaders for its INHBE siRNA therapy, a first-in-class treatment designed to achieve fat-selective weight loss while preserving lean muscle mass. The company plans to investigate this therapy as both a monotherapy and in combination with GLP-1s to address current limitations in obesity care regarding body composition.PR NewswireVial Initiates Phase 1 Trial of VIAL-INHBE, an INHBE (Activin E) siRNA for the Treatment of ObesityVial, a clinical-stage biotechnology company based in San Francisco, has initiated a Phase 1 first-in-human trial for VIAL-INHBE, a novel GalNAc-conjugated siRNA targeting INHBE (Activin E) for the treatment of obesity and other cardiometabolic diseases. The trial, being conducted in Australia as an open-label, single-ascending dose study, will evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics, with interim data expected in the first half of 2026 and a multi-region Phase 2 trial planned for later that year. Preclinical data in diet-induced obese mice demonstrated fat-selective weight loss, lean mass preservation, and synergistic weight loss effects when combined with a low-dose GLP-1 therapy.BioSpaceVial Initiates Phase 1 Trial of VIAL-INHBE, an INHBE (Activin E) siRNA for the Treatment of ObesityVial, a clinical-stage biotechnology company based in San Francisco, announced the initiation of a Phase 1 first-in-human trial for VIAL-INHBE, a novel INHBE (Activin E) siRNA being developed for obesity and other cardiometabolic diseases. The single-ascending dose trial will evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of a subcutaneous dose, with interim data expected in the first half of 2026 and a multi-region Phase 2 trial in obesity planned for later that year. Preclinical data in DIO mouse models demonstrated that VIAL-INHBE combined with a lower GLP-1 dose achieved comparable total body weight loss to high-dose GLP-1 while preserving lean mass and reducing post-treatment weight rebound.VentureRadarTop dermatology start-upsNumerous start-ups focused on dermatological innovation and solutions have emerged, including Concerto Biosciences, VIATRIS, and Vial, all founded in 2020 and based in the USA. These companies are developing a range of therapeutic products, technologies, and approaches, highlighting the growing interest in dermatology as a specialized field within healthcare. The article showcases a variety of companies from different countries, indicating a broader trend in the growth of the dermatological market.RadioinkBiotech Podcast ‘First In Human’ Getting Its Second SeasonClinical trial manager Vial is launching the second season of its biotech podcast, 'First in Human,' with a premiere date of September 5. The new season will feature interviews with industry leaders such as executives from ONL Therapeutics, ProteinQure, and LatchBio to discuss breakthroughs and challenges in the sector.Business InsiderThe CEO of buzzy healthtech startup Vial, which slashed up to 50 jobs last year, asked remaining employees to write positive Glassdoor reviewsVial CEO Simon Burns asked remaining employees to write positive Glassdoor reviews after the company laid off 40-50 people. The request raised Vial's rating from one star to 3.8 out of five, based on 25 reviews. Former employees cited a toxic culture and low morale.