PhenoTips
PhenoTips is a Toronto-based SaaS company providing a cloud-based Genomic Health Record platform for clinical genetics workflows, serving hospital systems, NHS trusts, and genetics clinics across 60+ countries with pedigree management, HPO-based phenotyping, and AI-driven genomic test requisition.
- Company typePrivate
- Founded2014
- HeadquartersToronto, Canada
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What PhenoTips does
PhenoTips (legally Gene42 Inc.) is a Toronto-based clinical genomics software company founded in 2014 out of a research collaboration between the University of Toronto and the Hospital for Sick Children. The company provides a cloud-based Genomic Health Record (GHR) platform purpose-built for clinical genetics workflows, integrating pedigree drawing, structured phenotyping using the Human Phenotype Ontology (HPO), cancer risk assessment, pre-visit patient questionnaires, and EHR connectivity. The platform serves clinical geneticists, genetic counselors, hospital informatics teams, and increasingly non-genetics specialists through its AI-assisted SmartRequisition product. PhenoTips is deployed across more than 60 countries in five languages and is used by approximately 1 in 4 NHS trusts in the UK, alongside major Canadian pediatric hospitals including SickKids, CHEO, CHU Sainte-Justine, IWK Health, and Alberta Health Services.
The underlying technology combines domain-specific clinical software with AI-driven natural language processing. Core features include the Pedigree Maker tool (supporting gender-inclusive and single-parent family structures), HPO-based phenotype capture with Concept Recognition that auto-extracts standardized terms from free-text clinical notes, a Cancer Risk Assessment tool running four simultaneous risk models (including CanRisk V2/BOADICEA V6), and integration with Epic and other EHR systems. In March 2026, PhenoTips launched the SmartRequisition AI platform through the CIPHER national initiative, backed by CAD $5.4M in Genome Canada funding, automating genomic test requisition workflows for non-genetics specialists. The platform is HIPAA, GDPR, SOC2 Type 2, DSPT, and CE+ certified and holds the DiMe Seal.
PhenoTips operates a sales-led go-to-market with enterprise field sales targeting healthcare institutions, NHS trusts, and genetics clinics via demo requests and direct account executive outreach. Revenue is generated through SaaS subscriptions on a quote-based, annual billing model with per-seat or site-based licensing. The company has raised approximately CAD $4.5 million in seed-stage equity across two rounds (2021 and 2025) and employs 20-30 people. The company is controlled by its three co-founders — Orion Buske (CEO), Pawel Buczkowicz (COO), and Michael Brudno (Chairman) — with 1% of equity pledged to rare disease charities via the Upside Foundation of Canada.
PhenoTips firmographics
Firmographics- Name
- PhenoTips
- Legal name
- Gene42 Inc.
- Website
- https://phenotips.com
- Company type
- Private
- Founded year
- 2014
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- PhenoTips is a Toronto-based SaaS company providing a cloud-based Genomic Health Record platform for clinical genetics workflows, serving hospital systems, NHS trusts, and genetics clinics across 60+ countries with pedigree management, HPO-based phenotyping, and AI-driven genomic test requisition.
- Ownership category
- akta.pro rank
PhenoTips industry classification
Industry- Product category
- Clinical Genetics Software
- NAICS
- Other Computer Related Services (541519)
- SIC
- Services-Prepackaged Software (7372), Services-Health Services (8000)
- akta.pro primary industry
- Clinical & Translational Informatics (Clinical Data Integration/Real-World Data for R&D) (HLAGAJAF)
- akta.pro secondary industries
- Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics) (HLAAALAD), Prognostic & Risk Stratification Biomarkers (disease progression, recurrence risk) (HLAAAMAF)
Keywords
Where PhenoTips is headquartered
LocationHeadquarters
- HQ city
- Toronto
- HQ country
- Canada
- HQ region
- North America
Offices1 record
Markets served
PhenoTips business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Marketing or Sales, Infrastructure, Operations
Revenue model
- SaaS Subscription: Cloud-based Genomic Health Record delivered as subscription software, likely with per-seat or site-based licensing for healthcare institutions.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Annual | Contact for pricing |
Go-to-market motion2 records
Distribution channels3 records
Marketing channels7 records
PhenoTips product offering
Product offeringCore offering
PhenoTips provides a cloud-based Genomic Health Record (GHR) SaaS platform for clinical genetics workflows. The platform unifies inclusive pedigree drawing, standardized phenotyping using the Human Phenotype Ontology (HPO), pedigree-embedded cancer risk assessment (BOADICEA/CanRisk), pre-visit patient questionnaires, and EHR integration (Epic). It serves genetic clinics, hospitals, NHS trusts, and research institutions across Canada, UK, US, and Europe.
Product overview
PhenoTips offers a unified Genomic Health Record platform with modular add-on features. The core platform (Core Genomic Health Record) provides foundational patient records, pedigree drawing (Pedigree Maker), and clinical insights (Structured Patient Data and Clinical Insights). Add-on modules include Cancer Risk Assessment for pedigree-embedded cancer risk calculations, Pre-Visit Patient Questionnaire for automated pedigree generation, and Seamless Integrations for EHR connectivity. Key features include WGS Test Ordering and AI-powered Concept Recognition for HPO term extraction from clinical notes.
Differentiator
Problem solved
Functional benefit
Products and services
- Genomic Health Record The core EHR-integrated Genomic Health Record SaaS platform that digitizes medical genetics workflows, including patient records, phenotype capture, pedigree management, and clinical insights. Built for genetic clinics, hospitals, NHS trusts, and research institutions.
- Pedigree Maker Digital tool for creating advanced, inclusive pedigree charts with support for gender-diverse families, single-parent structures, and automated pedigree generation from patient-entered data. For clinical geneticists, genetic counselors, and genetics clinics.
- Structured Patient Data and Clinical Insights Next-generation phenotyping tool that leverages the Human Phenotype Ontology (HPO) for standardized symptom capture, gene and disease suggestions using Orphanet and OMIM, and diagnosis insights. For clinical genetics departments seeking faster diagnosis.
- Cancer Risk Assessment Pedigree-embedded cancer risk assessment tool that launches four simultaneous risk models including BOADICEA V6 and CanRisk Ovarian Risk Model, calculating risk scores for any family member without redundant data entry. For oncology departments and cancer genetics programs.
- Pre-Visit Patient Questionnaire Digital questionnaire sent to patients before visits to capture family history, automatically generating editable pedigree charts and enabling pre-visit triage. For clinical genetics departments seeking streamlined workflows.
- SmartRequisition AI Platform AI-powered platform that automates genomic test requisition workflows by converting clinical notes into structured lab requisitions, reducing symptom coding time by 67% and targeting 80% requisition completeness. For non-genetics specialists ordering genetic tests across Canadian health institutions.
Quantifiable outcome
- 30x faster diagnosis for users leveraging gene and diagnosis suggestions
- +4 more outcomes
Companies that use PhenoTips
Customer profileNamed customers13 records
Segments3 records
Ideal customer profiles2 records
PhenoTips technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration2 records
AI capability6 records
Feature7 records
PhenoTips partnerships and signals
Strategic signalPartnerships
Six partnerships are on record, tiered core and minor.
- IWK HealthcoreCo-leading the $5.4 million CIPHER national AI initiative to develop SmartRequisition AI platform. IWK Health is a children's hospital in Halifax, Nova Scotia.
- Alberta Health ServicescoreCIPHER network partner handling over 15,000 genomic cases per year. One of four provinces participating in SmartRequisition validation.
- CHU Sainte-JustinecoreCIPHER network partner in Quebec, one of four provinces handling 15,000+ genomic cases annually for SmartRequisition validation.
- SickKids (Hospital for Sick Children)coreCIPHER network partner, one of Canada's leading children's hospitals and founding institution of PhenoTips.
- CHEOcoreCIPHER network partner, children's hospital in Ottawa handling significant genomic case volume.
- Upside Foundation of Canada / CHEO Foundation / SickKids Foundation / CORDminorPhenoTips pledged 1% equity to Upside Foundation supporting CHEO Foundation, SickKids Foundation, and Canadian Organization for Rare Disorders (CORD) to advance rare disease research.
Scale indicators12 records
Recent moves9 records
Expansion highlights6 records
PhenoTips competitors and assessment
Company assessmentDirect peers
- SOPHiA Genetics: Genomics AI platform used by hospitals and labs for clinical genomics interpretation and rare disease analysis. Directly comparable to PhenoTips as a software layer for clinical genomics workflows, although SOPHiA's emphasis is more on variant interpretation than pedigree/phenotype capture.
- Fabric Genomics: Clinical decision support and interpretation platform for genomic data, deployed in hospital systems. Directly comparable as a software partner enabling genetics workflows in clinical settings, overlapping with PhenoTips' genomic health record positioning.
- Congenica: Clinical genomics interpretation platform used by NHS labs and hospital systems for rare disease diagnostics. Direct peer in clinical genomics software, with particularly strong NHS overlap similar to PhenoTips.
- 2bPrecise (EHR-integrated precision medicine): Precision medicine platform that brings genomic insights into the EHR workflow. Comparable to PhenoTips in delivering genomics-aware tools embedded within Epic and other EHR environments for clinical teams.
Emerging players
- DNAnexus: Cloud-based platform for genomics data management and clinical interpretation. Comparable as a software infrastructure layer serving clinical and research genomics, though DNAnexus sits more upstream of the clinical workflow than PhenoTips.
- GenomOncology: Clinical genomics decision support focused on oncology workflows. Comparable to PhenoTips' cancer genetics offering in providing risk assessment and structured genomics data within clinical workflows.
Broad incumbents
- Epic Systems (Genomics Module): Dominant hospital EHR vendor with growing native genomics, pedigree, and structured-data features. Already integrates with PhenoTips but represents the largest competitive risk as it builds comparable functionality natively.
- Foundation Medicine: Established molecular diagnostics and genomic profiling company operating at much larger scale. Broad incumbent in clinical genomics that defines infrastructure PhenoTips integrates with rather than directly competes against.
Others
- GeneDx: Clinical genetic testing laboratory with a digital portal and structured reporting tools. Comparable ecosystem participant that consumes structured phenotype/HPO data of the kind PhenoTips captures.
- Invitae: Large clinical genetic testing company building digital tools for clinicians and patients. Adjacent ecosystem participant with overlapping customer base (clinical genetics teams) that PhenoTips serves.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat6 records
Key risks5 records
Key highlights6 records
Customer concentration
PhenoTips social profiles
Digital presencePhenoTips compliance and trust
Trust signalCompliance6 records
PhenoTips financial estimates
Financial estimateRevenue estimate
Valuation estimate
PhenoTips leadership team
Management profileNumber of profiles
Profiles4 records
PhenoTips funding detail
Funding detailFunding overview
Funding rounds8 records
Investors9 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
PhenoTips M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about PhenoTips
What does PhenoTips do?
PhenoTips provides a cloud-based Genomic Health Record (GHR) SaaS platform for clinical genetics workflows. The platform unifies inclusive pedigree drawing, standardized phenotyping using the Human Phenotype Ontology (HPO), pedigree-embedded cancer risk assessment (BOADICEA/CanRisk), pre-visit patient questionnaires, and EHR integration (Epic). It serves genetic clinics, hospitals, NHS trusts, and research institutions across Canada, UK, US, and Europe.
Is PhenoTips a public or private company?
PhenoTips is a private company. It is classified as venture growth investor backed and is currently operating.
When was PhenoTips founded?
PhenoTips was founded in 2014. It employs 11 to 50 people.
Where is PhenoTips based?
PhenoTips is headquartered in Toronto, Canada, in the North America region.
How does PhenoTips make money?
One revenue line is on record: saaS Subscription.
Who are PhenoTips's main competitors?
Direct peers on record are SOPHiA Genetics, Fabric Genomics, Congenica and 2bPrecise (EHR-integrated precision medicine). Emerging players are DNAnexus and GenomOncology. Broad incumbents are Epic Systems (Genomics Module) and Foundation Medicine. Others are GeneDx and Invitae.
Does PhenoTips have an API?
No public API is recorded for PhenoTips.
What industry is PhenoTips in?
PhenoTips's product category is Clinical Genetics Software. Its primary akta.pro industry code is HLAGAJAF, Clinical & Translational Informatics (Clinical Data Integration/Real-World Data for R&D), with a secondary code of HLAAALAD, Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics). Its NAICS code is 541519 and its SIC code is 7372.