Amplitude Venture Capital

What Amplitude Venture Capital does

Amplitude Ventures Inc. is a Canadian venture capital firm, formally established in 2018, with its founding team active in precision-medicine investing since 2012. The firm creates, builds, and grows precision medicine companies through three integrated offerings: (i) venture capital investment services deploying capital into Canadian and select US biotechs, (ii) Pre-Amp, an internal biotech creation studio that partners with academia and global company builders to discover, incubate, and fund innovation through proof-of-concept data, and (iii) the Pre-Amp / Amplitude Fellowship, a summer program that brings together Canadian PhD candidates, postdocs, and MDs to explore biotech concepts as the first step in new venture creation. Since 2012, the founding team has raised over $700 million of equity capital in private and public markets, with the first dedicated private capital fund of $200 million launched in November 2019.

The firm's business model is structured around venture capital returns from equity investments in portfolio companies, with revenue derived from management fees on committed capital and carried interest on successful exits. Portfolio activity has spanned multiple therapeutic areas and modalities, including Repare Therapeutics (IPO), Celsius Therapeutics (acquired), Valence Labs (exited), Fluid Biomed (exited), Deep Genomics, Abdera Therapeutics, Congruence Therapeutics (AI-powered protein folding), Mediar Therapeutics (fibrosis), Prilenia, Thryv, Ability Biotherapeutics, Evommune, and Nomic (proteomics). Co-leads alongside Dimension, OrbiMed, and ICG, and syndication with Silver Arc, Lumira, BDC Capital, Asahi Kasei Pharma Ventures, and Alexandria Real Estate Trust, indicate a distributed syndication network across North America.

Amplitude operates from four Canadian offices (Montreal headquarters at 3 Place Ville-Marie; Toronto at MaRS Discovery District; Calgary at The Ampersand; Vancouver) and serves three primary constituencies: precision medicine companies seeking capital and operational support, biotech founders and entrepreneurs seeking experienced partners, and institutional investors (limited partners) seeking exposure to a precision-medicine venture thesis. Investments are sourced through direct founder relationships, warm introductions, the Pre-Amp creation studio, academic partnerships, and participation in the broader biotech ecosystem.

Name

Amplitude Venture Capital

Legal name

Amplitude Ventures Inc.

Website

https://amplitudevc.com/en

Company type

Private

Founded year

2018

Operating status

Operating

Headcount range

11–50 employees

Short description

Amplitude Ventures is a Canadian venture capital firm that creates, builds, and grows precision medicine companies through equity investment, the Pre-Amp biotech creation studio, and the Pre-Amp Fellowship program. It serves biotech founders, portfolio companies, and institutional investors across North America.

Ownership category

akta.pro rank

Product category

Life Sciences Venture Capital

NAICS

Other Investment Pools and Funds (5259), Funds, Trusts, and Other Financial Vehicles (525), Portfolio Management and Investment Advice (523940)

SIC

Investment Advice (6282)

akta.pro primary industry

Venture Studios / Company Builders (FSANAAAH)

akta.pro secondary industry

Sector-Focused Venture Capital (Vertical Specialists) (FSANAAAD)

Keywords

• Venture capital investing
• Precision medicine funding
• Biotech company building
• Life sciences investment
• Startup equity capital

Headquarters

HQ city

Montréal

HQ country

Canada

HQ region

North America

Offices4 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Venture Capital Returns: Amplitude generates returns through equity investments in portfolio companies. Since 2012, the founding team has raised over $700 million of equity capital in private and public markets. The firm launched its first private capital fund in November 2019, a $200-million fund.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

Amplitude Ventures is a Canadian venture capital firm and company builder that creates, builds, and grows precision medicine companies by deploying equity capital and providing strategic, operational, and board-level support. The firm supplements direct investing with an internal biotech creation studio called Pre-Amp (which discovers, incubates, and funds innovation from academia) and a talent-development fellowship program for PhD candidates, postdocs, and MDs. Its first dedicated private capital fund of $200 million was launched in November 2019.

Product overview

Amplitude Ventures is a venture capital firm that operates as a company builder for precision medicine companies. The firm offers venture capital investment services as its core offering, complemented by Pre-Amp (an internal biotech creation studio for discovering, incubating, and funding innovation) and the Amplitude Fellowship (a talent development program for PhD candidates and postdocs). Since 2012, the founding team has raised over $700 million of equity capital and launched its first private capital fund in November 2019, a $200-million fund focused on leading Canadian precision medicine companies.

Differentiator

Problem solved

Functional benefit

Brands

• Pre-Amp: Amplitude's internal biotech creation studio for discovering, incubating, and funding innovation.
• Pre-Amp Fellowship

Products and services

• Venture Capital Investment Services Venture capital equity financing combined with active company-building support for precision medicine companies. The firm deploys growth capital, takes board seats, and works with founders on strategy, fundraising, talent, and operational decisions to scale companies to breakout potential. Available to founders and management teams of precision medicine and biotech companies (primarily in Canada, with selective U.S. investments).
• Pre-Amp Biotech Creation Studio Amplitude's internal biotech creation studio that discovers, incubates, and funds precision medicine innovation by partnering with academia and global company builders to advance proof-of-concept data and create new companies. Targeted at academic researchers and prospective company builders whose discoveries can seed new portfolio companies.
• Amplitude / Pre-Amp Fellowship A summer fellowship program that brings together Canada's brightest PhD candidates, postdocs, MDs, and inventors to explore biotech concepts, identify hypotheses for novel healthcare ventures, and cultivate the next generation of precision medicine leaders. Targeted at health-science graduate researchers and academic inventors.

Quantifiable outcome

• Over $700M equity capital raised since 2012
• +2 more outcomes

Named customers8 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature1 record

Partnerships

Three partnerships are on record, tiered core and minor.

• Pre-AmpcoreStrategic or Co-development PartnerPre-Amp is Amplitude's internal biotech creation studio that discovers, incubates, and funds innovation. It partners with academia and company builders globally to advance proof-of-concept data and enable discovery of revolutionary treatments.
• NomicminorStrategic or Co-development PartnerNomic is a portfolio company that partnered with the Wellcome Sanger Institute to bring protein-level resolution to the genetics of immune diversity.
• Wellcome Sanger InstituteminorStrategic or Co-development PartnerWellcome Sanger Institute partnered with Nomic (an Amplitude portfolio company) to integrate Omni-1000 proteomics into discovery and translational workflows.

Scale indicators6 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Lumira Ventures: Lumira Ventures is a Canadian healthcare-focused venture capital firm investing in early- and growth-stage biotech and medical technology companies. It is the closest Canadian peer to Amplitude, having co-invested in Congruence Therapeutics alongside Amplitude and sharing a sector-focused, Canada-anchored investment thesis.
• BDC Capital Healthcare Venture Fund: BDC Capital operates healthcare and life sciences venture funds that invest in Canadian biotech and healthtech companies. As a Crown corporation with deep Canadian biotech roots and co-investor status in deals such as Congruence Therapeutics, it is a directly comparable domestic peer to Amplitude.

Regional players

• Real Ventures: Real Ventures is a Montreal-based early-stage VC firm with a sector-relevant life sciences practice. Its geographic and biotech overlap with Amplitude, including Montreal ecosystem ties, makes it a regionally relevant peer for talent and deal flow competition.
• Anges Québec: Anges Québec is a Quebec-based angel and early-stage investment network with growing life sciences activity. It is a regionally relevant peer for Canadian biotech deal flow and complementary to Amplitude's Montreal-focused sourcing strategy.

Broad incumbents

• Versant Ventures: Versant Ventures is a large healthcare-specialized venture firm operating across North America and Europe with multiple billion-dollar funds. It is comparable as a sector-focused biotech investor with company-creation capabilities, but at a far larger scale than Amplitude, serving as both co-investor and competitor for breakthrough biotech opportunities.
• OrbiMed: OrbiMed is one of the largest healthcare-dedicated investment firms globally, with $17B+ AUM across venture, growth, and credit. It is a directly relevant peer because it co-led Congruence Therapeutics' round with Amplitude, reflecting overlapping precision medicine deal flow, but operates at a vastly larger scale.
• Atlas Venture: Atlas Venture is a Boston-based biotech-focused venture firm that builds companies from inception through its in-house company-creation model. Its venture studio model and precision medicine focus closely mirror Amplitude's Pre-Amp approach, but at a substantially larger AUM scale.
• ARCH Venture Partners: ARCH Venture Partners is a large US biotech venture firm known for founding companies from academic research. Comparable to Amplitude in founding-company DNA and precision medicine mandate, but with multi-billion-dollar AUM and longer track record of large-scale biotech creation.
• Flagship Pioneering: Flagship Pioneering is a Boston-based biotech creation platform that originates and builds breakthrough companies. Its venture studio approach to building companies from scientific concepts is structurally similar to Amplitude's Pre-Amp, though Flagship operates at a vastly larger scale and has spawned multi-billion-dollar public companies.

Others

• Alexandria Venture Investments: Alexandria Venture Investments is the strategic venture arm of Alexandria Real Estate Equities, focused on life sciences investments. As a co-investor in Mediar Therapeutics and a strategic capital source for biotech ecosystems, it is an adjacent, capital-providing peer that overlaps with Amplitude in precision medicine deal flow.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/amplitude-ventures

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments36 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Amplitude Venture Capital