What Again does

Again is a Copenhagen-based climate technology company that converts industrial CO2 emissions into commercial-grade chemicals using a proprietary platform combining AI-designed biocatalysts, modular biomanufacturing reactors, and gas fermentation. The company's technology uses acetogenic bacteria refined through more than a decade of research originating at the Danish Technical University, Stanford, and MIT to transform CO2-rich industrial flue gases into an acetate intermediary, which serves as a building block for a portfolio of drop-in end products including commodity chemicals, acetone, aroma and flavor compounds, coloring solutions, personal care ingredients, industrial enzymes, proteins, and fertilizers.

The company operates three facilities across Denmark, the United States, and Norway. CPH-1 in Copenhagen has been live since April 2023, capturing and converting up to one ton of industrial CO2 per day from a Biofos wastewater treatment plant and accumulating over 25,500 consecutive active hours. TXS-1 in Texas City is the company's first US commercial-scale facility, developed in partnership with Dow Chemical, HELM AG, and Macquarie, with planned lifetime CO2 abatement of 32,000 tonnes. NOR-1 in Norway is part of the EU Horizon-funded PyroCO2 consortium and is designed to consume over 10,000 tonnes of industrial CO2 annually to produce up to 4,000 tonnes of green acetone per year. Modular reactor design enables project deployment in approximately 12 months, materially shorter than the 3-4 year timeline for conventional chemical plant construction.

Revenue is generated through B2B enterprise sales of CO2-derived chemicals, with primary distribution handled through a strategic offtake partnership with HELM AG. The company's customer base consists of large industrial chemical producers, chemical offtakers, government entities, and industrial CO2 emitters. Pricing is not publicly disclosed and contracts are negotiated on a project basis. The company has raised approximately $98 million cumulatively across funding rounds, including a $43 million Series A led by GV (Google Ventures) and HV Capital in July 2024.

Name

Again

Legal name

Again

Website

https://again.bio

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

11–50 employees

Short description

Again is a Copenhagen-based climate tech company that uses AI-designed biocatalysts and modular gas fermentation reactors to convert industrial CO2 emissions into commodity chemicals, acetone, flavors, enzymes, proteins, and fertilizers for industrial chemical buyers and offtakers.

Ownership category

akta.pro rank

Product category

Carbon Utilization Chemicals

NAICS

Other Basic Organic Chemical Manufacturing (32519), Chemical Manufacturing (325)

SIC

Industrial Organic Chemicals (2860), Chemicals & Allied Products (2800)

akta.pro primary industry

CO₂‑to‑Chemicals (C1/C2+ chemicals: formic acid, CO, syngas, ethylene/propylene pathways) (EUABAIAC)

akta.pro secondary industries

Bio-based Platform & Commodity Chemicals (e.g., bio-ethylene, bio-propylene, bio-BTX, bio-methanol) (EUAAAIAA), Bio-based Solvents & Process Chemicals (e.g., bio-acetone, bio-butanol, bio-IPA, green solvents) (EUAAAIAB)

Keywords

• Carbon capture chemicals
• CO2 utilization
• Industrial biotechnology
• Biocatalytic manufacturing
• Gas fermentation

Headquarters

HQ city

Copenhagen

HQ country

Denmark

HQ region

Europe

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Operations, Personnel, Infrastructure, Marketing or Sales

Revenue model

1. CO2-Derived Chemical Products: Revenue generated from selling carbon-negative chemical products produced from industrial CO2 emissions. Products include acetate (platform intermediary), acetone, aroma and flavors, coloring solutions, personal care ingredients, industrial enzymes, proteins, commodity chemicals, and fertilizers. Products are sold to industrial manufacturers as drop-in solutions meeting industrial standards.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels4 records

Core offering

Again operates the Again Platform, which uses AI-designed biocatalysts and modular biomanufacturing to convert industrial CO2 emissions into commercial-grade chemicals. Products span commodity chemicals (acetate, acetone), fertilizers, proteins, industrial enzymes, aroma and flavor compounds, coloring solutions, and personal care ingredients, sold as drop-in solutions meeting industrial standards. Three facilities (CPH-1 in Copenhagen, TXS-1 in Texas, NOR-1 in Norway) produce these chemicals directly from live industrial CO2 feedstock.

Product overview

Again operates as a climate tech company offering a vertically-integrated biomanufacturing platform. The core Again Platform combines AI-designed biocatalysts with modular bio-reactors to convert industrial CO2 emissions into a portfolio of end products including Aroma & Flavors, Coloring Solutions, Personal Care ingredients, Industrial Enzymes, Proteins, Commodity Chemicals, and Fertilizers. The platform uses an acetate intermediary as a core building block for chemicals, fertilizers, and food products. The company offers modular, made-to-assemble technology for rapid project deployment, taking projects from start to go-live in 12 months.

Differentiator

Problem solved

Functional benefit

Products and services

• Again Platform
• Aroma & Flavors
• Coloring Solutions
• Personal Care
• Industrial Enzymes
• Proteins
• Commodity Chemicals
• Fertilizers

Quantifiable outcome

• 1 ton per day CO2 conversion capacity at CPH-1 facility
• +3 more outcomes

Named customers4 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability2 records

Feature4 records

Partnerships

Five partnerships are on record, tiered core and flagship.

• UnibiocoreStrategic or Co-development Partner · 1 January 2024Again and Unibio collaborate on the Gas2X research project, exploring conversion of industrial waste gases into scalable low-carbon products. The project aims to establish a national platform for gas-based biomanufacturing in Denmark. New gas fermentation platform will be installed at Unibio's Innovation Centre in Kalundborg, complementing Unibio's existing U-Loop methane-to-protein technology.
• Dow ChemicalflagshipStrategic or Co-development Partner · 1 January 2023Dow Chemical is Again's flagship partner for TXS-1, the first commercial facility on US soil in Texas City. The partnership validates Again's technology at commercial scale and demonstrates seamless integration into existing industrial infrastructure. Dow provides CO2 emissions as feedstock and industrial site integration.
• HELM AGflagshipChannel Partner/ Reseller/ Distributor · 1 January 2023HELM AG partners with Again for offtake and distribution of chemical products from TXS-1 to customers locally, regionally, and internationally. Contributes to reshoring of production for critical chemicals in the region.
• MacquariecoreStrategic or Co-development Partner · 1 January 2023Macquarie is a partner in the TXS-1 project, providing financing and investment support for the commercial-scale deployment of Again's CO2 conversion technology.
• BiofoscoreStrategic or Co-development Partner · 1 January 2022Biofos operates the large-scale wastewater treatment plant providing live industrial CO2 emissions for CPH-1 facility in Copenhagen. Partnership established Spring 2022. One of the largest CO2 utilization projects in Europe.

Scale indicators11 records

Recent moves6 records

Expansion highlights7 records

Market position

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/secondcirclebio

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Subsidiaries3 records

Funding overview

Funding rounds4 records

Investors8 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Again