Medrio

What Medrio does

Medrio, founded in 2005 and headquartered in San Francisco, is a privately held provider of cloud-based eClinical software for clinical trials, serving pharmaceutical, biotechnology, medical device, contract research organization (CRO), and animal health customers. The company's unified platform combines Electronic Data Capture and Clinical Data Management (EDC/CDMS) with integrated modules for electronic Clinical Outcome Assessments and Patient-Reported Outcomes (eCOA/ePRO), electronic consent (eConsent), Randomization and Trial Supply Management (RTSM), Clinical Trial Management System (CTMS), and electronic Trial Master File (eTMF), the latter two powered by Engility technology. The platform is differentiated by no-code, point-and-click eCRF configuration enabling study builds in hours to days, real-time data synchronization across modules, zero-downtime mid-study changes validated in a sandbox environment, and device-agnostic BYOD support for patient-reported outcomes.

Medrio generates revenue primarily through subscription-based SaaS licensing for its eClinical platform, complemented by professional services including Clinical Data Services (a team of 17 experts offering build, biostatistics, and database lock support) and Clinical Trial Project Management. Go-to-market combines direct enterprise field sales, a CRO Partner Program with tiered pricing and growth rewards, and a Functional Service Provider (FSP) model for embedded clinical data expertise. The company maintains ISO 27001 certification, FDA 21 CFR Part 11 compliance, HIPAA, GDPR, and CCPA adherence, positioning the platform for regulated, audit-ready deployments across global trials.

The company is venture-backed, with Questa Capital as a primary growth investor, and operates across 30+ countries with thousands of studies deployed. Strategic direction has been reinforced by founder Mike Novotny returning as CEO in 2025, the February 2026 Trialt partnership, the 2021 acquisition of HMD Clinical, and multiple 2026 G2 awards recognizing the platform for user adoption, implementability, and customer support.

Name

Medrio

Legal name

Medrio, Inc.

Website

https://medrio.com

Company type

Private

Founded year

2005

Operating status

Operating

Headcount range

101–250 employees

Short description

Medrio provides a unified cloud-based eClinical platform combining EDC/CDMS with eCOA/ePRO, eConsent, RTSM, CTMS, and eTMF modules, serving pharmaceutical, biotech, medical device, CRO, and animal health organizations running clinical trials globally.

Ownership category

akta.pro rank

Product category

eClinical Software for Clinical Trials

NAICS

Computer Systems Design Services (541512)

SIC

Services-Prepackaged Software (7372)

akta.pro primary industry

Decentralized & Hybrid Trial Site Services (Home Health/Nursing) (HLAGACAH)

akta.pro secondary industry

DTx/SaMD Evidence, Outcomes & Real-World Data (RWE) Platforms (HLACANAM)

Keywords

• Electronic data capture
• EClinical platform
• Clinical trial management
• Patient reported outcomes
• Randomization trial supply

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations

Revenue model

1. Software Subscriptions: SaaS-based clinical trial technology platform offered as subscription. Unlimited user access with transparent pricing.
2. Clinical Data Services: Expert-led support for study builds, data management, biostatistics, and database lock. Team of 17 experts with 300 years of combined industry experience.
3. Clinical Trial Project Management: Dedicated project management team for implementation, protocol reviews, and ongoing trial support.
4. CRO Partner Program: Tiered pricing with rewards for growth. Enables CROs to take on more work while staying focused on execution.

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels9 records

Core offering

Medrio provides a unified, cloud-based eClinical platform that combines CDMS/EDC with eCOA/ePRO, eConsent, RTSM, CTMS, and eTMF capabilities, designed for clinical trial sponsors, CROs, and medical device companies. The platform is paired with expert-led Clinical Data Services and Clinical Trial Project Management to support study builds, mid-study changes, and database lock for complex studies with rapid deployment timelines.

Product overview

Medrio offers a unified eClinical platform combining CDMS/EDC with integrated modules including eCOA/ePRO, eConsent, RTSM, CTMS, and eTMF (powered by Engility). The core CDMS/EDC serves as the central data management system, while eCOA/ePRO enables patient-reported outcomes collection, eConsent manages informed consent workflows, RTSM handles randomization and supply management, CTMS provides operational oversight, and eTMF manages trial documentation. Professional services including Clinical Trial Project Management and Clinical Data Services complement the software suite, offering dedicated expert support from study setup through database lock.

Differentiator

Problem solved

Functional benefit

Brands

• Engility®: Power technology for Medrio's CTMS and eTMF software solutions
• MyMedrio

Products and services

• CDMS/EDC Core Electronic Data Capture and Clinical Data Management System combining real-time data access, mid-study changes without downtime, and no-code point-and-click eCRF configuration for clinical trial sponsors and CROs running complex studies.
• eCOA/ePRO Electronic Clinical Outcome Assessment and Electronic Patient-Reported Outcomes module that captures outcomes via a web-based, device-agnostic interface (BYOD), collecting in-clinic or remote data with validated and custom surveys for trial participants and clinicians.
• eConsent Electronic informed consent solution enabling remote or in-clinic consent workflows with multimedia content, quizzes, FAQs, version control, and re-consent management for trial participants, meeting ALCOA++ standards.
• RTSM Randomization and Trial Supply Management module providing automated randomization, inventory control, adaptive treatment allocation, stratification, kit assignment, and real-time supply chain tracking with temperature controls.
• CTMS Clinical Trial Management System, powered by Engility, that centralizes operational oversight for study planning, site management, monitoring, enrollment, milestones, and quality metrics, with automated monitoring and document workflows.
• eTMF Electronic Trial Master File, powered by Engility, automating document filing and compliance tracking to maintain inspection readiness from Day 1, with automatic completeness tracking, expiry date monitoring, and auditor-friendly selective access views.
• Clinical Trial Project Management Dedicated project management service supporting trial execution including mid-study changes, custom query configuration, hardware setup, and risk mitigation expertise, with a single point of contact and 24/7/365 global support.
• Clinical Data Services Expert-led Functional Service Provider data management support covering study builds, data strategy, process optimization, biostatistical analysis, and regulatory-ready outputs, delivered by a team of 17 clinical data experts.

Quantifiable outcome

• 9-week faster study builds
• +6 more outcomes

Named customers11 records

Segments5 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

Feature7 records

Partnerships

Six partnerships are on record, tiered minor, core and major.

• XtalksminorGTM or Marketing Partner · 15 April 2026Xtalks hosting a free webinar on April 15, 2026 featuring Cameron Kinnear from Medrio discussing integrated remote SDV workflows and AI-assisted innovations for clinical trial organizations.
• TrialtcoreStrategic or Co-development Partner · 10 February 2026Strategic partnership integrating Medrio's Electronic Data Capture (EDC) software into Trialt's clinical data management services. The partnership enables clients to access real-time clinical trial data, implement mid-study changes without downtime, and deploy the platform through an easy-to-learn environment. The clinical data management industry is projected to reach USD 8.9 billion by 2034.
• TrialtcoreStrategic or Co-development Partner · 9 February 2026Partnership strengthens Trialt's clinical data management capabilities, enabling real-time trial data access, mid-study changes with zero downtime, and faster deployment environment for sponsors, CROs, and study teams.
• CRO Partner NetworkcoreChannel Partner/ Reseller/ DistributorCRO Partner Program designed to extend CRO capacity without adding internal overhead. Includes enablement training, co-marketing opportunities, transparent tiered pricing with rewards for growth, and change management support. Featured partners include CTRG, CliniLabs, DP Clinical, and Visby Medical.
• FreenomemajorTechnology or IntegrationLong-term partnership enabling Freenome's large-scale clinical trials for early cancer detection. Medrio provides CDMS/EDC, eCOA/ePRO, and eConsent solutions across three clinical trials with 60,000+ participants across 200+ sites. Partnership includes API integrations for customized reporting and real-time performance insights.
• EngilitycoreTechnology or IntegrationPowered by Engility technology for CTMS and eTMF solutions. Engility provides the compliance engine for document filing, tracking completeness, and inspection readiness.

Scale indicators6 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Medidata Solutions (Dassault Systèmes): The dominant EDC/CDMS vendor via the Rave platform, serving the same pharma, biotech, and CRO customers with electronic data capture and adjacent eClinical modules. Closest direct competitor to Medrio in clinical trial technology.
• Castor: Cloud-based EDC and eClinical platform targeting small-to-mid sized sponsors and CROs with a similar ease-of-use value proposition. Direct mid-market competitor to Medrio's core 'small and scaling clinical teams' segment.
• Signant Health: Provider of eCOA/ePRO, RTSM, and patient-centric clinical trial technology directly competing with Medrio's eCOA/ePRO and RTSM modules. Strong overlap in patient-reported outcomes and randomization offerings.

Broad incumbents

• Veeva Systems: Life sciences cloud platform whose Vault CDB and Vault EDC compete directly with Medrio, while its broader Vault suite covers CTMS, eTMF, and quality — making it both a direct EDC peer and a broad-suite incumbent.
• Oracle Health Sciences (Clinical One): Broad life sciences suite (Clinical One, Inform, Siebel CTMS) competing across EDC, randomization, and trial management. Larger incumbent with deeper enterprise penetration than Medrio.
• Clario (formerly ERT): Large clinical trial technology vendor covering eCOA, cardiac safety, imaging, and RTSM. Competes with Medrio in patient-reported outcomes and randomization, with broader adjacent capabilities.
• IBM Clinical Development: Enterprise eClinical platform from IBM with EDC, ePRO, and CTMS modules. Direct overlap with Medrio's unified platform strategy at the large-sponsor end of the market.
• ArisGlobal: Life sciences R&D technology platform offering CTMS, eTMF, safety, and regulatory — overlapping Medrio's CTMS/eTMF modules and competing for the same mid-market sponsor segment.
• Veeva Vault eTMF / CTMS: Veeva's specialized CTMS and eTMF offerings compete directly with Medrio's Engility-powered CTMS/eTMF modules, particularly for sponsors already standardized on the Veeva ecosystem.

Emerging players

• OpenClinica: Open-source and cloud EDC platform serving academic, government, and smaller commercial trials. Overlaps with Medrio's ease-of-use positioning for resource-constrained clinical teams.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/medrio

Compliance6 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles18 records

Funding overview

Funding rounds4 records

Investors6 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Medrio