What Alpha Omega does

Alpha Omega Engineering, founded in 1993 in Nazareth, Israel by Imad and Reem Younis, designs and manufactures neurophysiology recording and stimulation systems used in neuroscience research and functional neurosurgery, with particular focus on Deep Brain Stimulation (DBS) navigation. The company's clinical portfolio centers on the Neuro Omega family of microelectrode recording (MER) systems (Neuro Omega, Neuro Omega Pro, NeuroSmart, NeuroNav), the AlphaProbe multi-channel microelectrode, and the HaGuide AI-assisted navigation software suite (including HaGuide Brain Map and LeadConfirm) for intraoperative brain mapping. The research portfolio is anchored by the alphaRS Pro neural data acquisition platform supporting up to 1024 channels with closed-loop control, complemented by motorized commutators (AlphaComm-I/A), acute electrodes, and Injectrodes. The αCare SENS cloud platform extends the company into longitudinal DBS patient management for neurologists.

Alpha Omega monetizes through a mix of medical device hardware sales, recurring software licenses (HaGuide and navigation tools), annual DBS service packages covering equipment maintenance, navigation software, target confirmation, and intraoperative support, and subscription access to the αCare SENS platform. Pricing is enterprise contract-based and not publicly disclosed. The go-to-market is direct enterprise field sales through wholly owned offices in Israel (HQ), the United States (Norcross, GA), Germany (Ubstadt-Weiher), and China (Guangzhou), augmented by a global distribution partnership with Medtronic initiated in 2019 and selected regional distributors. The company serves neurosurgeons, electrophysiologists, movement disorder neurologists, neuroscience researchers, and indirectly patients with Parkinson's disease, dystonia, and essential tremor, with equipment installed in approximately 300 hospitals across 40+ countries.

The company employs over 100 people globally including 50+ engineers, holds 5 granted patents with 17 pending, and reports 60% US and >30% EU market share in DBS navigation and microelectrode recording. Alpha Omega remains privately held, profitable according to ownership commentary, and reports being present in thousands of DBS procedures annually with its support reps attending more than 400 surgeries per year.

Name

Alpha Omega

Legal name

Alpha Omega Engineering

Website

https://alphaomega-eng.com

Company type

Private

Founded year

1993

Operating status

Operating

Headcount range

101–250 employees

Short description

Alpha Omega Engineering, founded 1993 in Israel, develops microelectrode recording systems, AI-based DBS navigation software (HaGuide), and neural data acquisition hardware used by neurosurgeons, electrophysiologists, and neuroscience researchers across 300+ hospitals in 40+ countries, distributed directly and via Medtronic.

Ownership category

akta.pro rank

Headquarters

HQ city

Nazareth

HQ country

Israel

HQ region

Middle East

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Medical Device Hardware Sales: Sale of neurophysiology recording systems, microelectrode recording systems, neuromodulation navigation systems, drives and headstages, accessories, and consumables for neuroscience research and neurosurgery procedures.
2. Software Licenses: Navigation software licenses including HaGuide, NeuroNav, and other clinical software solutions for DBS procedures.
3. Service Packages: DBS support service packages including on-site expert visits, technical and clinical support, navigation software license, target entry and exit confirmation, lead positioning confirmation, equipment maintenance, and preventive maintenance services.
4. αCare SENS Platform: Patient management software for surgeons and movement disorder neurologists with EMR integration capabilities.

Pricing tiers

Go-to-market motion2 records

Distribution channels6 records

Marketing channels5 records

Core offering

Alpha Omega designs, manufactures, and sells neurophysiology recording and stimulation systems for neuroscience research and functional neurosurgery, with a primary focus on Deep Brain Stimulation (DBS) navigation and microelectrode recording (MER) solutions. Its product portfolio spans neuroscience research data acquisition systems (alphaRS Pro, AlphaComm commutators, electrodes), clinical neurosurgery systems (Neuro Omega Pro, Neuro Omega, NeuroSmart, NeuroNav with HaGuide AI-based navigation), and the αCare SENS cloud-based DBS patient management platform, complemented by DBS service packages with on-site intraoperative support.

Product overview

Alpha Omega is a medical technology company offering integrated solutions across three domains: Neuroscience Research, Neurosurgery (DBS), and Neurology Patient Management. The neuroscience portfolio centers on the alphaRS Pro data acquisition system (up to 1024 channels) for electrophysiology research with restrained and free-moving subjects, complemented by motorized commutators (AlphaComm-I/A), acute electrodes, and Injectrodes. The neurosurgery portfolio centers on neuromodulation navigation systems (Neuro Omega Pro, Neuro Omega, NeuroSmart, NeuroNav) for DBS procedures, supported by HaGuide software suite (AlphaProbe, HaGuide Brain Map, LeadConfirm) for real-time brain mapping and AI-assisted navigation. Accessories include drives/headstages (NeuroFortis, Autoclavable Drive), consumables (cannula, electrodes, cables), and peripherals (NeuroMic, Remote Control, Stimulation Pedal). The neurology portfolio features the αCare SENS cloud platform for DBS patient management. The company also provides DBS service packages including on-site support, training, and maintenance.

Differentiator

Problem solved

Functional benefit

Brands

• αCare SENS: A platform supporting neurologists and patients through different stages of the patient's healthcare journey with movement disorders, digitizing and visualizing DBS management.
• Neuro Omega
• NeuroSmart
• NeuroNav
• HaGuide
• AlphaComm
• alphaRS
• NeuroFortis

Products and services

• alphaRS Pro Neural Data Acquisition System High-performance neural data acquisition system supporting up to 1024 recording channels with real-time closed-loop control and integrated electrical stimulation (up to 256 channels), designed for neuroscience research with restrained and free-moving subjects.
• AlphaComm-I Motorized Commutator Motorized commutator that senses and tracks rotations induced in tethers connected to freely moving animals, preventing cable entanglement while maintaining noise-free high-quality signals.
• Acute Electrodes Acute tungsten glass-coated microelectrodes available in different diameters and lengths for high-quality neural recording and stimulation in acute experimental protocols.
• Injectrodes Versatile electrodes enabling simultaneous neural recording and fluid injection for neuroscience research applications.
• Neuro Omega Pro Neuromodulation System Advanced neuromodulation navigation system integrating lead placement confirmation and predictive outcome technologies for DBS procedures, supporting MER and LFP acquisition.
• Neuro Omega MER System FDA and CE approved clinical MER (microelectrode recording) system with up to 122 channels, integrated HaGuide real-time STN navigation, online data streaming to MATLAB/C++, and integrated stimulation capabilities for DBS surgery.
• NeuroSmart Portable MER System Portable MER system with advanced target localization capabilities, built-in FDA/CE approved HaGuide navigation, MATLAB data access, and 5 SPK + 5 LFP channels for DBS procedures.
• NeuroNav Compact MER System Compact MER system for clinical localization of surgical targets during DBS implantation procedures, designed for stereotactic neurosurgery applications.
• HaGuide DBS Navigation Software Suite Suite of DBS navigation software tools providing real-time data and statistics from MER and DBS-lead LFP signals, including AlphaProbe, HaGuide Brain Map, and LeadConfirm modules.
• HaGuide Brain Map Detection Algorithm Semi-automatic detection algorithm trained to detect borders of target structures (STN DLOR and VMNR boundaries) and recommend optimal stimulation locations using MER data.
• LeadConfirm LFP Recording Software Software for recording Local Field Potentials (LFPs) intraoperatively from any DBS lead to ensure optimal lead placement, with monopolar and bipolar recording capabilities.
• NeuroFortis Automatic Motorized Drive Automatic motorized drive headstage with built-in amplifier, digitizer, and stimulator; compatible with all Alpha Omega systems for stereotactic surgery.
• αCare SENS DBS Patient Management Platform Cloud-based DBS patient management platform supporting neurologists and patients through movement disorder healthcare journeys, providing data from the OR (electrophysiological mapping, lead placement, LFP recordings) and clinic (symptom tracking, monopolar review, stimulation parameters).
• NeuroExplorer Data Analysis Software Neurophysiological data analysis software providing comprehensive spike train analysis options for processing data from Alpha Omega recording systems.
• DBS Service Packages Comprehensive on-site DBS support services including equipment maintenance, technical and clinical support, navigation software licenses, target entry/exit confirmation, lead positioning confirmation, and intraoperative troubleshooting.

Quantifiable outcome

• 60% US market share, >30% in EU market share in DBS navigation
• +3 more outcomes

Named customers10 records

Segments5 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration22 records

AI capability3 records

Feature6 records

Partnerships

One partnership is on record.

• MedtronicflagshipChannel Partner/ Reseller/ Distributor · 1 January 2019Since 2019, Alpha Omega and Medtronic have created a global partnership to bring Microelectrode Recording solutions to enhance workflow and make DBS implantation procedure simple, effective, and affordable. This partnership enables global distribution through Medtronic's Smart Surgical Suite initiative, combining Alpha Omega's MER technology with Medtronic's DBS leads and market reach.

Scale indicators9 records

Recent moves7 records

Expansion highlights5 records

Direct peers

• FHC Inc. US-based manufacturer of microelectrodes, micropositioners, and stereotactic frames used in DBS and single-unit recording. FHC competes most directly with Alpha Omega's microelectrode and drive/headstage portfolio, serving the same neurosurgery and research labs.
• Blackrock Microsystems: Designer of high-channel-count neural recording systems (up to 1024 channels) and electrode arrays for clinical and research use. Blackrock's NeuroPort and CerePlex systems are direct alternatives to Alpha Omega's alphaRS Pro and Neuro Omega lines for both BCI and DBS research.
• Tucker-Davis Technologies (TDT): Provider of electrophysiology data acquisition systems, signal processors, and experimental software for neuroscience laboratories. TDT's multi-channel recording platforms and SDK ecosystem overlap closely with Alpha Omega's research-instrument portfolio.
• Ripple Neuro: Manufacturer of neural recording and stimulation systems (e.g., the Grapevine and Nano2) for clinical and preclinical research. Ripple's hardware targets the same neuroscience-research customers as alphaRS and Neuro Omega for both free-moving and restrained experiments.
• Neuralynx: Supplier of high-channel neural data acquisition systems (Digital Lynx SX) and headstages used in academic neuroscience research. Neuralynx competes with Alpha Omega's research electrophysiology products among primate and rodent laboratories worldwide.
• Brain Products GmbH: European provider of EEG, MEG, and electrophysiology recording hardware (actiCHamp, LiveAmp) plus analysis software. Brain Products competes with Alpha Omega's neuroscience-research product line, particularly among academic labs focused on non-invasive and invasive neural recording.

Broad incumbents

• Medtronic: Global leader in DBS leads and implantable neurostimulators (Activa). Medtronic is also Alpha Omega's flagship distribution partner for MER solutions under the Smart Surgical Suite, giving it both an overlapping product line and a strategic channel relationship.
• Boston Scientific: Manufacturer of the Vercise DBS System, including directional leads and implantables. Boston Scientific competes with Alpha Omega's navigation/recording workflow at the lead-placement stage across the same neurosurgery customer base.
• Abbott: Producer of the Infinity DBS system and directional leads (via St. Jude Medical). Abbott is one of the three major DBS incumbent device makers whose leads Alpha Omega's LeadConfirm software is designed to be compatible with.
• Renishaw: Manufacturer of the Neuromate stereotactic robot used in DBS procedures. Renishaw's robotic systems overlap with Alpha Omega's navigation workflow and are commonly co-deployed with the Neuro Omega Pro in functional neurosurgery ORs.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/alphaomegaeng
• YouTubeyoutube.com/channel/UCvBEScA5xf3qLgeL5cRUhOQ
• Facebookfacebook.com/alpha-omega-engineering-350680594946401
• LinkedInlinkedin.com/company/alpha-omega

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Subsidiaries3 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Alpha Omega