Spatial Genomics
Spatial Genomics is a Pasadena-based life sciences tools company that sells the GenePS platform, powered by proprietary seqFISH technology, to academic researchers and pharma/biotech firms for multiplexed spatial genomics analysis of RNA, DNA, and proteins within intact tissues.
- Company typePrivate
- Founded2021
- HeadquartersPasadena, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Spatial Genomics does
Spatial Genomics, Inc. is a Pasadena, California-based life sciences tools company that develops and commercializes the GenePS (Gene Positioning System) platform, built around its proprietary sequential fluorescence in situ hybridization (seqFISH) technology. seqFISH merges high-resolution confocal imaging with combinatorial molecular barcoding, enabling highly multiplexed single-cell and subcellular analysis of RNA, DNA, and protein within intact tissues. The GenePS platform bundles an automated confocal imager, advanced fluidics, off-the-shelf and custom gene panels (ranging from approximately 220 to over 1,000 genes), and analysis software to support spatial transcriptomics, genomic organization studies, and proteomics in a single workflow.
The company monetizes primarily through direct, quote-based sales of GenePS instruments, proprietary reagents, gene panels, and bundled analysis software to academic and research institutions and to pharmaceutical and biotech companies working in neuroscience, developmental biology, oncology, and immunology. Its go-to-market is sales-led and enterprise-oriented, with a 'Request A Quote' call-to-action on the product page and multi-year contracts typical for capital instrument placements. The technology has been validated through extensive peer-reviewed publications in Nature, Science, Cell, Nature Methods, and Nature Biotechnology, and the company publishes downloadable sample datasets to support customer evaluation.
Spatial Genomics was founded with co-founders Kirsten Frieda (CEO) and Drew Kennedy (Vice President), maintains a headcount of 11–50 employees, and is headquartered at 145 Vista Ave Suite 111, Pasadena, CA 91107. The company raised a $56 million funding round on 2022-02-23 led by Fulgent Therapeutics with 12 West Capital also participating, providing the capital base to scale instrument placements, expand the gene-panel catalog, and grow the direct sales motion across global academic and pharma accounts.
Spatial Genomics firmographics
Firmographics- Name
- Spatial Genomics
- Legal name
- Spatial Genomics, Inc.
- Website
- https://spatialgenomics.com
- Company type
- Private
- Founded year
- 2021
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Spatial Genomics is a Pasadena-based life sciences tools company that sells the GenePS platform, powered by proprietary seqFISH technology, to academic researchers and pharma/biotech firms for multiplexed spatial genomics analysis of RNA, DNA, and proteins within intact tissues.
- Ownership category
- akta.pro rank
Spatial Genomics industry classification
Industry- Product category
- Spatial Genomics Instruments
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516)
- SIC
- In Vitro & In Vivo Diagnostic Substances (2835)
- akta.pro primary industry
- Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF)
- akta.pro secondary industries
- Multiplex & High-Throughput Diagnostics Platforms (microarrays, digital PCR, lab automation-enabled assays) (HLAAALAL), Transcriptomics & Gene Expression Profiling Services (HLAGANAE)
Keywords
Where Spatial Genomics is headquartered
LocationHeadquarters
- HQ city
- Pasadena
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Spatial Genomics business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales, Infrastructure
Revenue model
- GenePS platform sales: Sale of the GenePS automated instrument, associated reagents, and gene panels. The company offers both off-the-shelf gene panels (hundreds to over 1000 genes) and custom gene panels.
- Custom gene panels and reagents: Sale of off-the-shelf and custom gene panels to meet specific project research needs, combined with fluidics reagents for the GenePS system.
- Analysis software: Provision of analysis software as part of the complete spatial platform for data visualization and interpretation.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | GenePS platform with off-the-shelf panels |
Go-to-market motion1 record
Distribution channels1 record
Marketing channels4 records
Spatial Genomics product offering
Product offeringCore offering
Spatial Genomics develops and sells the GenePS (Gene Positioning System), an automated confocal imaging instrument integrated with advanced fluidics and analysis software. The platform is powered by proprietary seqFISH (sequential fluorescence in situ hybridization) technology, which combines imaging with combinatorial molecular barcoding to enable highly multiplexed, subcellular-resolution analysis of RNA, DNA, and protein within intact tissue samples.
Product overview
Spatial Genomics offers the GenePS (Gene Positioning System) as its core unified product platform, which combines an automated confocal imaging instrument with advanced fluidics, reagents, and analysis software. The platform is powered by seqFISH (sequential fluorescence in situ hybridization) technology, which merges imaging with combinatorial molecular barcoding to enable highly multiplexed single-cell analysis of RNA, DNA, and protein. Off-the-shelf and custom gene panels (220 to over 1,000 genes) and sequential immunofluorescence options extend the platform's multi-omic capabilities. The complete system enables subcellular imaging of biomolecules within intact tissue microenvironments, supporting applications in neuroscience, developmental biology, oncology, and immunology research.
Differentiator
Problem solved
Functional benefit
Brands
- GenePS: Gene Positioning System - an automated instrument that performs high quality spatial genomics experiments as part of the company's complete spatial platform including automated instruments, reagents, and analysis software. The GenePS is a sensitive confocal imager combined with advanced fluidics that enables spatial research through single-cell gene expression, protein expression, and genomic and epigenomic states within intact cells and tissues.
Products and services
- GenePS (Gene Positioning System) Automated confocal imaging instrument combined with advanced fluidics that performs highly multiplexed spatial genomics experiments for research institutions, academic labs, and pharmaceutical/biotech companies. Detects single-cell gene expression, protein expression, and genomic/epigenomic states within intact cells and tissues.
- Gene Panels Off-the-shelf and custom gene panels ranging from approximately 220 genes to over 1,000 genes (e.g., Mouse Kidney Mapper 220-gene panel, Mouse Signaling Panel 1,092 genes) used with the GenePS system for targeted spatial transcriptomics studies.
- Analysis Software Software included with the GenePS platform that allows researchers to review results, visualize cell type organization at the tissue level, and explore samples at subcellular resolution, including UMAP representations and sample data exploration tools.
Quantifiable outcome
- Mouse kidney data set contains 669,842 cells (unfiltered) with mean of 234 transcripts per cell for single z-section using 220-gene panel
- +1 more outcomes
Companies that use Spatial Genomics
Customer profileSegments2 records
Ideal customer profiles2 records
Spatial Genomics technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability1 record
Feature6 records
Spatial Genomics partnerships and signals
Strategic signalScale indicators1 record
Recent moves5 records
Expansion highlights6 records
Spatial Genomics competitors and assessment
Company assessmentBroad incumbents
- Bio-Techne: Bio-Techne's RNAscope in situ hybridization platform is the established gold-standard ISH method for spatial RNA detection and competes broadly with seqFISH in academic and translational research labs.
- Bruker: Bruker's acquisition of NanoString consolidates a major spatial omics portfolio (CosMx, GeoMx) under a large life-science instrumentation company, raising competitive and bundling pressure on smaller players like Spatial Genomics.
Direct peers
- 10x Genomics: 10x Genomics offers Visium and Xenium spatial transcriptomics platforms that compete directly with Spatial Genomics' GenePS for academic and pharma spatial omics budgets, targeting the same highly multiplexed single-cell tissue analysis use cases.
- NanoString Technologies (a Bruker company): NanoString's GeoMx digital spatial profiling and CosMx spatial molecular imager compete head-to-head with GenePS in multiplexed spatial transcriptomics and proteomics for research and translational labs.
- Vizgen: Vizgen's MERFISH-based spatial transcriptomics platform is a direct technical competitor to seqFISH, offering single-molecule, subcellular RNA mapping in intact tissue with similar gene-panel scale.
- Resolve Biosciences: Resolve Biosciences' Molecular Cartography platform performs highly multiplexed single-molecule spatial transcriptomics, directly competing with GenePS in neuroscience, oncology, and developmental biology applications.
- Akoya Biosciences: Akoya's PhenoCycler (CODEX) and Phenoptics platforms lead spatial proteomics and multiplex immunofluorescence, overlapping with Spatial Genomics' sequential immunofluorescence and multi-omic tissue imaging capabilities.
- RareCyte: RareCyte offers the Orion spatial biology platform for multiplexed RNA and protein analysis in tissue, positioning it as a comparable instrument-based spatial omics peer to GenePS.
Emerging players
- Curio Bioscience: Curio's Slide-seq and spatial transcriptomics kits offer an emerging alternative to imaging-based platforms like GenePS, particularly for researchers seeking higher-throughput, lower-cost spatial data.
- Rebus Biosystems: Rebus Biosystems' STAMP platform provides single-molecule, targeted spatial transcriptomics, overlapping with seqFISH's gene-panel approach but with a different instrumentation architecture.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights6 records
Customer concentration
Spatial Genomics social profiles
Digital presenceSpatial Genomics financial estimates
Financial estimateRevenue estimate
Valuation estimate
Spatial Genomics leadership team
Management profileNumber of profiles
Profiles2 records
Spatial Genomics funding detail
Funding detailFunding overview
Funding rounds1 record
Investors2 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Spatial Genomics M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Spatial Genomics
What does Spatial Genomics do?
Spatial Genomics develops and sells the GenePS (Gene Positioning System), an automated confocal imaging instrument integrated with advanced fluidics and analysis software. The platform is powered by proprietary seqFISH (sequential fluorescence in situ hybridization) technology, which combines imaging with combinatorial molecular barcoding to enable highly multiplexed, subcellular-resolution analysis of RNA, DNA, and protein within intact tissue samples.
Is Spatial Genomics a public or private company?
Spatial Genomics is a private company. It is classified as venture growth investor backed and is currently operating.
When was Spatial Genomics founded?
Spatial Genomics was founded in 2021. It employs 11 to 50 people.
Where is Spatial Genomics based?
Spatial Genomics is headquartered in Pasadena, United States, in the North America region.
How does Spatial Genomics make money?
Three revenue lines are on record. GenePS platform sales are the primary driver. The others are custom gene panels and reagents and analysis software.
Who are Spatial Genomics's main competitors?
Broad incumbents on record are Bio-Techne and Bruker. Direct peers are 10x Genomics, NanoString Technologies (a Bruker company), Vizgen, Resolve Biosciences, Akoya Biosciences and RareCyte. Emerging players are Curio Bioscience and Rebus Biosystems.
Does Spatial Genomics have an API?
No public API is recorded for Spatial Genomics.
What industry is Spatial Genomics in?
Spatial Genomics's product category is Spatial Genomics Instruments. Its primary akta.pro industry code is HLAGAIAF, Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays), with a secondary code of HLAAALAL, Multiplex & High-Throughput Diagnostics Platforms (microarrays, digital PCR, lab automation-enabled assays). Its NAICS code is 334516 and its SIC code is 2835.