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Drug Farm

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uuid0000kyo

Namestring
Drug Farm
Legal namestring
Shanghai Yaoyuan Shengwu Technology Co., Ltd. (上海药苑生物科技有限公司)
Websiteurl
drug-farm.com
Company typeenum
Private
Founded yearint
2015
Descriptiontext

Drug Farm is a clinical-stage biotechnology company founded in 2015 and headquartered in Shanghai, China, with operations in Albany, New York. The company combines two proprietary technology platforms—IDInVivo⁺, which uses piggyBac transposon mutagenesis to generate libraries of genetic mutations in mice for in vivo identification of novel drug targets in animals with intact immune systems, and MedChem5, a deep learning platform intended to accelerate medicinal chemistry optimization and first-in-class drug development. Applying these platforms, Drug Farm has built a pipeline of six drug candidates: DF-006 (hepatitis B and hepatocellular cancer), DF-003 (cardio-renal disease and ROSAH syndrome; first-in-class ALPK1 inhibitor), DF-004 (colitis), DF-005 (Alzheimer's disease), DF-007 (cancer), and DF-X1 (colitis/cancer).

The company's most clinically advanced asset, DF-003, has completed a Phase 1 trial in healthy volunteers and is accruing patients in a Phase 1b trial for ROSAH syndrome, a rare genetically driven systemic autoinflammatory disease with no approved disease-modifying therapy. In March 2026, DF-003 received FDA Orphan Drug Designation (conferring up to seven years of U.S. market exclusivity, fee waivers, and tax credits) and was accepted into the FDA Rare Disease Evidence Principles Process (RDEP). Drug Farm is privately held and venture-backed, having raised approximately $83 million across a $56 million Series B in February 2021 (investors include WuXi AppTec, BVCF, DT Capital Partners, and South China Venture Capital) and a $27 million Series C in May 2023 led by YD Capital.

Drug Farm's business model is that of a pre-revenue clinical-stage biopharmaceutical developer: the company has no marketed products, no disclosed pricing, and no commercial revenue. Operating expenses are funded by equity capital, with future monetization expected through potential partnerships, out-licensing, or eventual product commercialization. The company employs 51-100 staff, led by Founder and Chair Tian Xu (Ph.D.), Co-founder and COO Tony Xu (Ph.D.), and CEO Henri Lichenstein (Ph.D.). End-patient populations include those with infectious diseases (hepatitis B), immunological/inflammatory conditions (colitis, ROSAH syndrome), cardio-renal disease, neurodegenerative disease (Alzheimer's), and oncology indications, though in a clinical-stage context these are therapeutic targets rather than commercial customers.

Short descriptiontext

Drug Farm is a clinical-stage biotechnology company that uses proprietary in vivo genetics (IDInVivo⁺) and deep learning (MedChem5) platforms to discover and develop first-in-class immune-modulating therapies for hepatitis B, rare autoinflammatory diseases, and cancer.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
51–100
akta.pro rankint
HeadquartersShanghai, China
HQ citystring
Shanghai
HQ countrystring
China
HQ regionstring
Asia
Markets served

Serves global market

Offices2 records

Each record includes

City, Country, Type, Description, Source

Keyword5 values
immunotherapy drug discovery, genetic target identification, deep learning drug development, transposon mutagenesis platform, biopharmaceutical R&D
Industry3 codes
PRIMARYHLAAAIAI
HLAAAIAI
Healthcare & Life Sciences/Biotechnology & Biologics/Biologic Drug Discovery Platforms (screening, antibody engineering, synthetic biology)
SECONDARYHLAAAIAE
HLAAAIAE
Healthcare & Life Sciences/Biotechnology & Biologics/Biologic Drug Discovery Platforms (screening, antibody engineering, synthetic biology)
SECONDARYHLAAAIAL
HLAAAIAL
Healthcare & Life Sciences/Biotechnology & Biologics/Biologic Drug Discovery Platforms (screening, antibody engineering, synthetic biology)
NAICS code2 codes
  • 325414
  • 325412
SIC code2 codes
  • 2834
  • 2836
Product category
Biopharmaceuticals
Social media profiles1 record
Cost components4 values
Personnel, Technology or R&D, Operations, Supply Chain
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

Drug Farm is a clinical-stage biopharmaceutical company that develops first-in-class immune-modulating drug candidates using two proprietary platforms: IDInVivo+, which uses piggyBac transposon mutagenesis in mice to identify novel drug targets connected to host immunity, and MedChem5, which applies deep learning to accelerate first-in-class drug development. Its pipeline includes candidates for hepatitis B, hepatocellular cancer, cardio-renal disease, ROSAH syndrome, colitis, Alzheimer's disease, and cancer.

Differentiator
Functional benefit
Problem solved
Product overview1 text field

Drug Farm is a biopharmaceutical company that operates two integrated technology platforms: IDInVivo⁺ for novel target discovery using genetic screens in living animals, and MedChem5 for accelerating drug development using deep learning. Combining these platforms, the company has identified novel immunity targets and developed first-in-class drug candidates including DF-006 (hepatitis B/hepatocellular cancer), DF-003 (cardio-renal disease/ROSAH syndrome), DF-004 (colitis), DF-005 (Alzheimer's), DF-007 (cancer), and DF-X1 (cancer). The company's therapeutic focus areas include infection, immunological diseases, and oncology.

Product and service1 record
1DF-006
Scale indicator2 records

Each record includes

Type, Value, Description, Source

Recent move5 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

Clinical-stage biotech combining high-throughput biology, robotics, and AI/ML to discover and develop novel therapeutics at scale. Directly comparable to Drug Farm as a platform biotech using AI/computational approaches to identify novel drug targets and advance first-in-class candidates into the clinic.

TypeDirect peer
Description

Machine learning-driven drug discovery company combining wet-lab biology with AI to predict drug behavior and identify novel targets. Highly comparable to Drug Farm's MedChem5 platform and overall thesis of using AI to accelerate first-in-class drug development.

TypeDirect peer
Description

Computational chemistry and predictive software platform for drug discovery, with an internal pipeline of novel therapeutics. Comparable to Drug Farm as a platform company using computational/AI methods (analogous to MedChem5) to develop first-in-class drug candidates.

TypeDirect peer
Description

Generative AI biology company designing novel protein therapeutics computationally. Comparable to Drug Farm in combining AI with biology to produce first-in-class drug candidates, though focused on biologics while Drug Farm pursues small-molecule and biologic candidates.

TypeDirect peer
Description

Antibody discovery platform using data science and AI to identify novel therapeutic candidates from natural immune repertoires. Comparable to Drug Farm as a platform biotech using proprietary screening/diversity-generation technology (analogous to IDInVivo+) to feed a clinical pipeline.

TypeDirect peer
Description

Clinical-stage biotech developing therapies for chronic hepatitis B and other viral diseases. Direct peer for Drug Farm's DF-006 program in HBV/hepatocellular cancer, pursuing novel mechanisms to address the same large unmet need.

TypeDirect peer
Description

Clinical-stage biopharmaceutical company focused on developing a functional cure for chronic hepatitis B. Direct peer to Drug Farm's DF-006 HBV program, with overlapping therapeutic area and indication focus.

TypeDirect peer
Description

China-based clinical-stage biotech developing therapeutics for infectious diseases (including HBV) and central nervous system disorders. Direct peer to Drug Farm as a China-domiciled biotech pursuing similar infectious and immunological indications with global clinical ambitions.

TypeRegional player
Description

China-US headquartered biotech developing and commercializing innovative therapeutics, with particular focus on oncology, autoimmune diseases, and infectious diseases. Comparable to Drug Farm in bridging China and US clinical/commercial development, though broader in scope and further along commercially.

TypeBroad incumbent
Description

Global oncology-focused biotechnology company headquartered in China with major US operations. Broader incumbent peer to Drug Farm given shared China-US structure and clinical-stage biotech focus, though BeiGene has commercialized products and operates at much larger scale.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat4 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment1 record

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile1 record

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI capability1 record

Each record includes

Type, Description, Source

AI maturity
App detail

Has app

Feature2 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles13 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds3 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors19 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment1 record

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Drug Farm

Biopharmaceuticalsdrug-farm.com

Drug Farm is a clinical-stage biotechnology company that uses proprietary in vivo genetics (IDInVivo⁺) and deep learning (MedChem5) platforms to discover and develop first-in-class immune-modulating therapies for hepatitis B, rare autoinflammatory diseases, and cancer.

What Drug Farm does

Drug Farm is a clinical-stage biotechnology company founded in 2015 and headquartered in Shanghai, China, with operations in Albany, New York. The company combines two proprietary technology platforms—IDInVivo⁺, which uses piggyBac transposon mutagenesis to generate libraries of genetic mutations in mice for in vivo identification of novel drug targets in animals with intact immune systems, and MedChem5, a deep learning platform intended to accelerate medicinal chemistry optimization and first-in-class drug development. Applying these platforms, Drug Farm has built a pipeline of six drug candidates: DF-006 (hepatitis B and hepatocellular cancer), DF-003 (cardio-renal disease and ROSAH syndrome; first-in-class ALPK1 inhibitor), DF-004 (colitis), DF-005 (Alzheimer's disease), DF-007 (cancer), and DF-X1 (colitis/cancer).

The company's most clinically advanced asset, DF-003, has completed a Phase 1 trial in healthy volunteers and is accruing patients in a Phase 1b trial for ROSAH syndrome, a rare genetically driven systemic autoinflammatory disease with no approved disease-modifying therapy. In March 2026, DF-003 received FDA Orphan Drug Designation (conferring up to seven years of U.S. market exclusivity, fee waivers, and tax credits) and was accepted into the FDA Rare Disease Evidence Principles Process (RDEP). Drug Farm is privately held and venture-backed, having raised approximately $83 million across a $56 million Series B in February 2021 (investors include WuXi AppTec, BVCF, DT Capital Partners, and South China Venture Capital) and a $27 million Series C in May 2023 led by YD Capital.

Drug Farm's business model is that of a pre-revenue clinical-stage biopharmaceutical developer: the company has no marketed products, no disclosed pricing, and no commercial revenue. Operating expenses are funded by equity capital, with future monetization expected through potential partnerships, out-licensing, or eventual product commercialization. The company employs 51-100 staff, led by Founder and Chair Tian Xu (Ph.D.), Co-founder and COO Tony Xu (Ph.D.), and CEO Henri Lichenstein (Ph.D.). End-patient populations include those with infectious diseases (hepatitis B), immunological/inflammatory conditions (colitis, ROSAH syndrome), cardio-renal disease, neurodegenerative disease (Alzheimer's), and oncology indications, though in a clinical-stage context these are therapeutic targets rather than commercial customers.

Drug Farm firmographics

Firmographics
Name
Drug Farm
Legal name
Shanghai Yaoyuan Shengwu Technology Co., Ltd. (上海药苑生物科技有限公司)
Website
https://drug-farm.com
Company type
Private
Founded year
2015
Operating status
Operating
Headcount range
51–100 employees
Short description
Drug Farm is a clinical-stage biotechnology company that uses proprietary in vivo genetics (IDInVivo⁺) and deep learning (MedChem5) platforms to discover and develop first-in-class immune-modulating therapies for hepatitis B, rare autoinflammatory diseases, and cancer.
Ownership category
akta.pro rank

Where Drug Farm is headquartered

Location

Headquarters

HQ city
Shanghai
HQ country
China
HQ region
Asia

Offices2 records

Markets served

Drug Farm business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Personnel, Technology or R&D, Operations, Supply Chain

Drug Farm product offering

Product offering

Core offering

Drug Farm is a clinical-stage biopharmaceutical company that develops first-in-class immune-modulating drug candidates using two proprietary platforms: IDInVivo+, which uses piggyBac transposon mutagenesis in mice to identify novel drug targets connected to host immunity, and MedChem5, which applies deep learning to accelerate first-in-class drug development. Its pipeline includes candidates for hepatitis B, hepatocellular cancer, cardio-renal disease, ROSAH syndrome, colitis, Alzheimer's disease, and cancer.

Product overview

Drug Farm is a biopharmaceutical company that operates two integrated technology platforms: IDInVivo⁺ for novel target discovery using genetic screens in living animals, and MedChem5 for accelerating drug development using deep learning. Combining these platforms, the company has identified novel immunity targets and developed first-in-class drug candidates including DF-006 (hepatitis B/hepatocellular cancer), DF-003 (cardio-renal disease/ROSAH syndrome), DF-004 (colitis), DF-005 (Alzheimer's), DF-007 (cancer), and DF-X1 (cancer). The company's therapeutic focus areas include infection, immunological diseases, and oncology.

Differentiator

Problem solved

Functional benefit

Products and services

  • DF-006

Companies that use Drug Farm

Customer profile

Segments1 record

Ideal customer profiles1 record

Drug Farm technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

AI capability1 record

Feature2 records

Drug Farm partnerships and signals

Strategic signal

Scale indicators2 records

Recent moves5 records

Expansion highlights5 records

Drug Farm competitors and assessment

Company assessment

Direct peers

  • Recursion Pharmaceuticals: Clinical-stage biotech combining high-throughput biology, robotics, and AI/ML to discover and develop novel therapeutics at scale. Directly comparable to Drug Farm as a platform biotech using AI/computational approaches to identify novel drug targets and advance first-in-class candidates into the clinic.
  • Insitro: Machine learning-driven drug discovery company combining wet-lab biology with AI to predict drug behavior and identify novel targets. Highly comparable to Drug Farm's MedChem5 platform and overall thesis of using AI to accelerate first-in-class drug development.
  • Schrödinger, Inc. Computational chemistry and predictive software platform for drug discovery, with an internal pipeline of novel therapeutics. Comparable to Drug Farm as a platform company using computational/AI methods (analogous to MedChem5) to develop first-in-class drug candidates.
  • Generate Biomedicines: Generative AI biology company designing novel protein therapeutics computationally. Comparable to Drug Farm in combining AI with biology to produce first-in-class drug candidates, though focused on biologics while Drug Farm pursues small-molecule and biologic candidates.
  • AbCellera Biologics: Antibody discovery platform using data science and AI to identify novel therapeutic candidates from natural immune repertoires. Comparable to Drug Farm as a platform biotech using proprietary screening/diversity-generation technology (analogous to IDInVivo+) to feed a clinical pipeline.
  • Aligos Therapeutics: Clinical-stage biotech developing therapies for chronic hepatitis B and other viral diseases. Direct peer for Drug Farm's DF-006 program in HBV/hepatocellular cancer, pursuing novel mechanisms to address the same large unmet need.
  • Arbutus Biopharma: Clinical-stage biopharmaceutical company focused on developing a functional cure for chronic hepatitis B. Direct peer to Drug Farm's DF-006 HBV program, with overlapping therapeutic area and indication focus.
  • Brii Biosciences: China-based clinical-stage biotech developing therapeutics for infectious diseases (including HBV) and central nervous system disorders. Direct peer to Drug Farm as a China-domiciled biotech pursuing similar infectious and immunological indications with global clinical ambitions.

Regional players

  • Zai Lab: China-US headquartered biotech developing and commercializing innovative therapeutics, with particular focus on oncology, autoimmune diseases, and infectious diseases. Comparable to Drug Farm in bridging China and US clinical/commercial development, though broader in scope and further along commercially.

Broad incumbents

  • BeiGene: Global oncology-focused biotechnology company headquartered in China with major US operations. Broader incumbent peer to Drug Farm given shared China-US structure and clinical-stage biotech focus, though BeiGene has commercialized products and operates at much larger scale.

Market position

Strengths5 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

Drug Farm social profiles

Digital presence

Drug Farm financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Drug Farm leadership team

Management profile

Number of profiles

Profiles13 records

Drug Farm funding detail

Funding detail

Funding overview

Funding rounds3 records

Investors19 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Drug Farm M&A and investment

M&A and investment

M&A

Investments1 record

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Drug Farm

What does Drug Farm do?

Drug Farm is a clinical-stage biopharmaceutical company that develops first-in-class immune-modulating drug candidates using two proprietary platforms: IDInVivo+, which uses piggyBac transposon mutagenesis in mice to identify novel drug targets connected to host immunity, and MedChem5, which applies deep learning to accelerate first-in-class drug development. Its pipeline includes candidates for hepatitis B, hepatocellular cancer, cardio-renal disease, ROSAH syndrome, colitis, Alzheimer's disease, and cancer.

Is Drug Farm a public or private company?

Drug Farm is a private company. It is classified as venture growth investor backed and is currently operating.

When was Drug Farm founded?

Drug Farm was founded in 2015. It employs 51 to 100 people.

Where is Drug Farm based?

Drug Farm is headquartered in Shanghai, China, in the Asia region.

Who are Drug Farm's main competitors?

Direct peers on record are Recursion Pharmaceuticals, Insitro, Schrödinger, Inc., Generate Biomedicines, AbCellera Biologics, Aligos Therapeutics, Arbutus Biopharma and Brii Biosciences. Zai Lab is listed as a regional player. BeiGene is listed as a broad incumbent.

Does Drug Farm have an API?

No public API is recorded for Drug Farm.

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Live signals
FinancialContent Business PageDrug Farm Presents Positive Ophthalmologic and Systemic Findings from International Phase 1b Study of First-in-Class ALPK1 Inhibitor DF-003 in ROSAH Syndrome at APVRS 2026Drug Farm presented positive interim findings from its Phase 1b study of DF-003, an ALPK1 inhibitor, in ROSAH syndrome patients at APVRS 2026. The study of 11 patients showed improvements in visual function, anhidrosis, headache, and inflammatory biomarkers, with no serious adverse events. The company plans to advance DF-003 to a Phase 3 pivotal trial.MorningstarDrug Farm Presents Positive Ophthalmologic and Systemic Findings from International Phase 1b Study of First-in-Class ALPK1 Inhibitor DF-003 in ROSAH Syndrome at APVRS 2026Drug Farm presented interim Phase 1b data for DF-003, an ALPK1 inhibitor, at APVRS 2026, showing improvements in visual function, anhidrosis, headache, and inflammatory biomarkers in 11 patients. Three of five Chinese patients met ophthalmic response criteria, and the drug was well tolerated. The company plans to advance DF-003 to a Phase 3 pivotal trial.Business Wire BlogDrug Farm Presents Positive Ophthalmologic and Systemic Findings from International Phase 1b Study of First-in-Class ALPK1 Inhibitor DF-003 in ROSAH Syndrome at APVRS 2026Drug Farm presented interim Phase 1b data for DF-003, an ALPK1 inhibitor, in ROSAH syndrome at APVRS 2026. Five Chinese patients showed visual acuity gains, improved sweating, and reduced inflammatory biomarkers. The company plans a Phase 3 pivotal trial.citybizDrug Farm Closes on $55M in Push to Treat Rosah SyndromeDrug Farm, a dual-headquartered biopharmaceutical company developing treatments for the ultra-rare genetic autoinflammatory disorder Rosah syndrome, has closed a $55 million Series D funding round co-led by Shanghai Pudong Leading Area Investment Center and Shanghai Puxing Collaborative Private Equity Fund Partnership Enterprise. The company's lead drug candidate DF-003 has demonstrated evidence of clinical improvement across multiple symptoms of Rosah syndrome in an ongoing Phase 1b study and has received fast track, orphan drug, and other designations from the FDA. Proceeds from the round will advance Drug Farm's clinical and preclinical stage pipeline for Rosah syndrome, heart and kidney diseases, hepatitis B, and metabolic diseases.BioWorldDrug Farm bags $55M series D to advance AI-developed ALPK1 drugDrug Farm Biotechnology closed a $55 million Series D financing round to advance its AI-developed ALPK1 inhibitor, DF-003. The funds will support the drug’s phase III trial for ROSAH syndrome, a rare genetic condition that can cause blindness. This investment marks continued progress in treating this specific rare disease through targeted small molecule therapy.FinSMEsDrug Farm Raises $55M in First Close of Series D FundingDrug Farm raised $55M in its first Series D financing round, led by Shanghai Pudong Leading Area Investment Center and Shanghai Puxing Collaborative Private Equity Fund Partnership Enterprise. The company will use the funds to advance its clinical and preclinical pipeline, accelerate global clinical development, and expand R&D capabilities.AInvestDrug Farm completes first closing of $55M Series D financingDrug Farm, a biopharmaceutical company specializing in novel therapeutic development, has completed the first closing of its $55 million Series D financing round. The funding will support advancement of the company's drug candidates into later-stage clinical trials and ongoing research and development efforts. A second closing is expected in the coming months pending additional investor commitments.Business Wire BlogDrug Farm Completes First Closing of $55 Million Series D Financing to Advance Clinical and Preclinical Development PipelineDrug Farm announced the successful first closing of its $55 million Series D financing round, co-led by Shanghai Pudong Leading Area Investment Center and Shanghai Puxing Collaborative Private Equity Fund Partnership Enterprise, with participation from multiple new and existing investors. The proceeds will support the advancement of its clinical and preclinical pipeline, including DF-003 progressing into a Phase 3 trial for ROSAH syndrome and DF-006 for hepatitis B treatment. The company noted that DF-003 is among the first drugs developed with AI to enter a Phase 3 trial.FinancialContent Business PageDrug Farm Completes First Closing of $55 Million Series D Financing to Advance Clinical and Preclinical Development PipelineDrug Farm announced the successful first closing of a $55 million Series D financing round co-led by Shanghai Pudong Leading Area Investment Center and Shanghai Puxing Collaborative Private Equity Fund Partnership Enterprise, with participation from multiple new and existing investors. The proceeds will support advancement of Drug Farm's clinical and preclinical pipeline, including DF-003 entering Phase 3 trials for ROSAH syndrome and DF-006 continuing clinical development for hepatitis B. The financing reflects investor confidence in the company's AI-powered drug discovery platforms and first-in-class drug candidates.EqualOceanDrug Farm Raises $55 Million in First Closing of Series D FinancingDrug Farm announced on July 13 that it raised $55 million in the first closing of its Series D financing round, co-led by Shanghai Pudong Leading Zone Investment Center and Shanghai Puxing Xietong Private Equity Partnership, with participation from multiple new and existing investors including Keyuan Pharmaceutical and Haoyue Capital serving as exclusive financial adviser. The proceeds will advance the company's clinical and preclinical pipeline, particularly DF-003 for ROSAH syndrome and DF-006 for chronic hepatitis B, and support regulatory activities in major markets and global clinical development expansion. The financing was described by the company's founder as a milestone reflecting investor confidence in Drug Farm's AI-enabled drug discovery platforms and development strategy.