ScienceIO
ScienceIO (Cascade Bio, Inc.) built an API-first healthcare AI platform that transformed unstructured medical text into structured data, mapping terms to over 9 million medical concepts for digital health, provider, payor, and pharma customers. Acquired by Veradigm in March 2024 for approximately $140 million.
- Company typePrivate
- Founded2020
- HeadquartersBoston, United States
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What ScienceIO does
ScienceIO (legally Cascade Bio, Inc.) was a Boston-based healthcare AI company founded in 2020 by Will Manidis and Gaurav Kaushik, who previously worked together at genomics firm Foundation Medicine. The company built an API-first platform that converts unstructured medical text — clinical notes, EHR records, patient messages, diagnostic reports — into structured, searchable, and analyzable healthcare data in real-time. Its core product suite comprised four offerings: Structure, which maps medical terms to over 9 million healthcare concepts in a single API call; Identify, a purpose-built PHI detection model covering 18 HIPAA Safe Harbor categories with 97% preservation of Eponymous diseases; Redact, which removes PHI to enable privacy-safe data sharing; and Learn, an in-development AI fine-tuning module for custom model deployment. The platform is delivered as a REST API with Python SDK, cloud-native infrastructure, and supports up to 10,000 characters per call.
ScienceIO operated a hybrid go-to-market combining product-led growth (freemium API signup at app.science.io, self-serve onboarding, public documentation at docs.science.io) with enterprise direct sales anchored by healthcare organizations such as Mayo Clinic Platform. A documented case study demonstrated the platform identifying 55 confirmed triple-negative breast cancer cases from over 100,000 breast cancer patients in under one day — a task estimated to require 100+ manual work-years. Revenue mechanics combined subscription-based and usage-based pricing processed via Stripe. The company served six named vertical segments: digital health and telemedicine, healthcare providers and research institutions, payors, diagnostics and biomarkers, revenue cycle management, and pharmaceutical and biotech. ScienceIO was HIPAA-compliant as a Business Associate. In March 2024, ScienceIO was acquired by Veradigm for approximately $140 million, after raising roughly $16 million in disclosed funding from investors including Lachy Groom, Section 32, Quiet Capital, Toba Capital, DormRoomFund, Sea Lane Ventures, Swell Partners, Earl Grey Capital, and numerous angel investors.
ScienceIO firmographics
Firmographics- Name
- ScienceIO
- Legal name
- Cascade Bio, Inc.
- Website
- https://science.io
- Company type
- Private
- Founded year
- 2020
- Operating status
- Acquired
- Headcount range
- 11–50 employees
- Short description
- ScienceIO (Cascade Bio, Inc.) built an API-first healthcare AI platform that transformed unstructured medical text into structured data, mapping terms to over 9 million medical concepts for digital health, provider, payor, and pharma customers. Acquired by Veradigm in March 2024 for approximately $140 million.
- Ownership category
- akta.pro rank
ScienceIO industry classification
Industry- Product category
- Healthcare AI / Clinical NLP
- NAICS
- Research and Development in the Physical, Engineering, and Life Sciences (54171), Other Scientific and Technical Consulting Services (54169)
- SIC
- Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Clinical & Translational Informatics (Clinical Data Integration/Real-World Data for R&D) (HLAGAJAF)
- akta.pro secondary industries
- Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF) (HLAGAJAM), FHIR/HL7 Data Repositories & Canonical Data Models (HLACAIAI), Clinical Document & Data Exchange (C-CDA, CCD, Direct Messaging) (HLACABAI)
Keywords
Where ScienceIO is headquartered
LocationHeadquarters
- HQ city
- Boston
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
ScienceIO business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Infrastructure, Marketing or Sales, Operations
Revenue model
- API Subscription/Usage: ScienceIO offers paid API services with both free and paid tiers. Users can sign up and access products through app.science.io. Payment processing handled via Stripe. Recurring billing for subscription-based access to API endpoints.
- Usage-based API Access: API consumption-based pricing where customers pay based on usage volume. Volume capabilities include up to 10,000 characters per API call.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Freemium | Pay-as-you-go | Free tier for API access |
| Subscription | Monthly | Paid API services |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels5 records
ScienceIO product offering
Product offeringCore offering
ScienceIO provides a healthcare-specialized AI/NLP platform delivered via REST API that converts unstructured medical text — clinical notes, EHR records, patient messages, and diagnostic reports — into structured, enriched, and analyzable data in real time. Its three core products (Structure, Identify, Redact) map medical terms to over 9 million concepts, identify Protected Health Information across 18 HIPAA Safe Harbor categories, and redact PHI to enable safe data sharing for developers and healthcare enterprises.
Product overview
ScienceIO is a healthcare AI platform consisting of three core products (Identify, Redact, and Structure) plus one in-development module (Learn). The platform converts unstructured healthcare data into structured, enriched formats. Identify finds and extracts Protected Health Information (PHI) for patient profiles and record integration. Redact removes PHI from documents for privacy protection. Structure maps medical terms to 9+ million healthcare concepts via API. Learn (coming soon) enables AI fine-tuning for custom needs. These products work together to enable use cases including patient cohorting, digital health analytics, clinical trial recruitment, revenue cycle management, and healthcare data automation.
Differentiator
Problem solved
Functional benefit
Products and services
- Structure AI-powered medical text analysis product that finds and maps medical terms in documents to over 9 million concepts with a single API call, transforming unstructured healthcare data into structured, searchable, analyzable formats in real time. Designed for developers and digital health companies integrating healthcare AI into their products.
- Identify Protected Health Information (PHI) identification product that finds patient information across 18 HIPAA Safe Harbor categories to enable building patient profiles and integrating medical records. Purpose-built for healthcare, preserving 97% of Eponymous diseases.
- Redact PHI redaction product that protects patient privacy by removing Protected Health Information from any document, enabling safe data sharing and anonymization of patient records for downstream analytics and research.
Quantifiable outcome
- 55 confirmed triple-negative breast cancer cases identified in less than 1 day from 100k+ breast cancer patients (vs. 100+ work years for manual review)
- +3 more outcomes
Companies that use ScienceIO
Customer profileNamed customers1 record
Segments6 records
Ideal customer profiles6 records
ScienceIO technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- Yes
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability2 records
Feature4 records
ScienceIO partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core and major.
- VeradigmcoreScienceIO was acquired by Veradigm in March 2024 for approximately $140 million. The acquisition aims to develop AI-enabled capabilities for Veradigm's healthcare data and analytics offerings.
- Mayo Clinic PlatformmajorScienceIO partnered with Mayo Clinic Platform to demonstrate patient cohort identification capabilities on millions of de-identified patient records. The collaboration showcased rapid identification of complex cohorts including triple-negative breast cancer cases.
Scale indicators6 records
Recent moves6 records
Expansion highlights5 records
ScienceIO competitors and assessment
Company assessmentDirect peers
- Apixio (acquired by Datavant): Healthcare NLP platform historically focused on risk adjustment and clinical data extraction from charts. Closely comparable to ScienceIO's Structure and Identify products for payer and provider use cases.
- John Snow Labs: Healthcare-specialized NLP and AI platform offering Spark NLP and medical entity extraction. Directly comparable to ScienceIO in addressing unstructured clinical text with healthcare-tuned models and API access for the same enterprise buyer (providers, pharma).
Emerging players
- Datavant: Health data connectivity and de-identification platform focused on linking patient records across systems. Closely comparable to ScienceIO's Redact and Identify PHI capabilities with stronger emphasis on record linkage and tokenization.
- Mendel.ai: Clinical AI platform applying NLP to medical records for cohort identification and real-world evidence. Directly comparable to ScienceIO's patient cohorting and clinical trial recruitment use cases with a competing developer-friendly product.
Broad incumbents
- Tempus: AI-powered precision medicine company with library of clinical and molecular data plus NLP capabilities for structuring medical records. Comparable to ScienceIO's biomedical language platform, especially around real-world data and biomarker extraction.
- CitiusTech: Healthcare technology services and analytics firm serving providers, payers, and life sciences. Competes with ScienceIO in clinical data integration and analytics, with a heavier services-led model rather than pure API.
- Health Catalyst: Healthcare data and analytics platform serving providers and life sciences. Overlaps with ScienceIO in clinical data structuring and analytics use cases, though more focused on enterprise data warehousing than NLP APIs.
- AWS HealthLake: AWS's HIPAA-eligible service for ingesting, structuring, and querying health data using FHIR and Comprehend Medical. Competes with ScienceIO at the data structuring and PHI layer, bundled into AWS's broader cloud ecosystem.
- Google Cloud Healthcare API: Google's managed service for healthcare data interoperability and NLP, with AutoML Entity Extraction for healthcare. Overlaps with ScienceIO's Structure and Identify products as part of a broader cloud data platform.
- Microsoft Cloud for Healthcare: Microsoft's vertically-oriented healthcare data and AI offering, integrating Azure Health Data Services and Text Analytics for Health. Comparable to ScienceIO as an end-to-end unstructured-data platform for healthcare organizations.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
ScienceIO social profiles
Digital presenceScienceIO compliance and trust
Trust signalCompliance1 record
ScienceIO financial estimates
Financial estimateRevenue estimate
Valuation estimate
ScienceIO leadership team
Management profileNumber of profiles
Profiles9 records
ScienceIO funding detail
Funding detailFunding overview
Funding rounds3 records
Investors17 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
ScienceIO M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about ScienceIO
What does ScienceIO do?
ScienceIO provides a healthcare-specialized AI/NLP platform delivered via REST API that converts unstructured medical text — clinical notes, EHR records, patient messages, and diagnostic reports — into structured, enriched, and analyzable data in real time. Its three core products (Structure, Identify, Redact) map medical terms to over 9 million concepts, identify Protected Health Information across 18 HIPAA Safe Harbor categories, and redact PHI to enable safe data sharing for developers and healthcare enterprises.
Is ScienceIO a public or private company?
ScienceIO is a private company. It is classified as corporate owned and is currently acquired.
When was ScienceIO founded?
ScienceIO was founded in 2020. It employs 11 to 50 people.
Where is ScienceIO based?
ScienceIO is headquartered in Boston, United States, in the North America region.
How does ScienceIO make money?
Two revenue lines are on record. API Subscription/Usage is the primary driver. The others are usage-based API Access.
Who are ScienceIO's main competitors?
Direct peers on record are Apixio (acquired by Datavant) and John Snow Labs. Emerging players are Datavant and Mendel.ai. Broad incumbents are Tempus, CitiusTech, Health Catalyst, AWS HealthLake, Google Cloud Healthcare API and Microsoft Cloud for Healthcare.
Does ScienceIO have an API?
Yes. ScienceIO provides a REST API that enables developers to transform unstructured medical text into structured, enriched healthcare data. The API supports real-time processing of up to 10,000 characters per call and can map medical terms to over 9 million concepts. Developers can access the API to build applications for patient cohort identification, digital health analysis, and healthcare data automation. The platform is described as cloud-native and provides scalable, secure API access. Developer documentation is at docs.science.io/docs.
What industry is ScienceIO in?
ScienceIO's product category is Healthcare AI / Clinical NLP. Its primary akta.pro industry code is HLAGAJAF, Clinical & Translational Informatics (Clinical Data Integration/Real-World Data for R&D), with a secondary code of HLAGAJAM, Clinical Trial Informatics (EDC/CTMS/eCOA/eTMF). Its NAICS code is 54171 and its SIC code is 8731.