Refeyn
Refeyn, founded in 2018 from the University of Oxford, commercializes mass photometry, a label-free optical technology that measures the mass of individual molecules and viral vectors in solution, selling instruments, automated systems, consumables, and GMP-compliant software to biopharma, CDMOs, and academic researchers in cell and gene therapy, biologics, and structural biology.
- Company typePrivate
- Founded2018
- HeadquartersOxford, United Kingdom
- Headcount101–250
- GTM typeB2B
- OfferingHardware or Manufacturing
What Refeyn does
Refeyn is a privately held life sciences instrumentation company, founded in 2018 and spun out of the University of Oxford, that develops and commercializes mass photometry, a label-free optical technology for measuring the mass of individual molecules in solution without the use of labels or denaturation. The platform detects light-scattering interference as molecules bind to a glass surface, enabling single-molecule resolution across proteins, nucleic acids, antibody complexes, mRNA and lipid nanoparticles, and viral vectors including AAV, adenoviral, and lentiviral vectors.
The company's product portfolio comprises four core benchtop mass photometers (TwoMP for general molecular mass, MyMassMP for structural biology sample QC, SamuxMP for AAV characterization, and KaritroMP for large viral vectors), automated walkaway variants (TwoMP Auto and SamuxMP Auto), a microfluidics add-on (MassFluidix HC), a GMP-compliant software suite supporting 21 CFR Part 11 and EU GMP Annex 11, and a recurring consumables line including MassGlass slides, MassFerence and SizeFerence calibrants, and alignment kits.
Refeyn generates revenue through a combination of direct enterprise sales of quote-priced instruments, a global distributor network covering markets including China and Japan, a self-serve US eShop for consumables, and recurring service contracts plus software licensing for regulated environments. Its customer base spans large pharma (AstraZeneca), government research (NIH/NHLBI), CDMOs (ABL Europe), and academic structural biology groups, with primary use cases in cell and gene therapy analytics, biologics and bispecific antibody characterization, mRNA therapeutics, structural biology screening, and contract analytical services.
Refeyn firmographics
Firmographics- Name
- Refeyn
- Legal name
- Refeyn Ltd.
- Website
- https://refeyn.com
- Company type
- Private
- Founded year
- 2018
- Operating status
- Operating
- Headcount range
- 101–250 employees
- Short description
- Refeyn, founded in 2018 from the University of Oxford, commercializes mass photometry, a label-free optical technology that measures the mass of individual molecules and viral vectors in solution, selling instruments, automated systems, consumables, and GMP-compliant software to biopharma, CDMOs, and academic researchers in cell and gene therapy, biologics, and structural biology.
- Ownership category
- akta.pro rank
Refeyn industry classification
Industry- Product category
- Analytical Laboratory Instruments
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516)
- SIC
- Laboratory Analytical Instruments (3826)
- akta.pro primary industry
- Mass Spectrometry & Spectroscopy Instruments (HLAGAIAB)
- akta.pro secondary industries
- Analytical Instruments & Chromatography Systems (HLAGAIAA), Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE)
Keywords
Where Refeyn is headquartered
LocationHeadquarters
- HQ city
- Oxford
- HQ country
- United Kingdom
- HQ region
- Europe
Offices2 records
Markets served
Refeyn business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales, Infrastructure
Revenue model
- Mass Photometry Instruments: Sale of benchtop mass photometry instruments (TwoMP, MyMassMP, SamuxMP, KaritroMP) and automated variants. Instruments are quote-priced with installation and support services included.
- Consumables: Recurring revenue from consumables including MassGlass sample prep kits (UC, NA, Auto formats), MassFerence calibrants, MassFluidix kits, Alignment kits, and SizeFerence calibrants. Sold via eShop for US customers and quote request for international.
- Service Contracts and Support: Service contracts for instrument maintenance, technical support, and installation/operational qualifications (IQ/OQ) particularly for GMP environments.
- Software Licenses: GMP-compliant software packages for regulatory environments including ManageMP, AcquireMP, EvaluateMPS for FDA 21 CFR Part 11 compliance.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | Consumables sold via eShop with direct pricing |
| Other | Multi-year contract | Instrument pricing requires quote request |
Go-to-market motion3 records
Distribution channels3 records
Marketing channels6 records
Refeyn product offering
Product offeringCore offering
Refeyn manufactures and sells benchtop mass photometry instruments that measure the molecular mass of individual proteins, nucleic acids, AAV capsids, and large viral vectors in solution without labels, returning results in 1–5 minutes from nanogram-scale samples. The portfolio includes the TwoMP (general molecular mass), MyMassMP (structural biology QC), SamuxMP (AAV characterization), and KaritroMP (large viral vectors), supported by a consumables line (MassGlass prep kits, MassFerence/SizeFerence calibrants) and a GMP-compliant software suite for regulated biopharma environments.
Product overview
Refeyn offers a portfolio of mass photometry instruments—a label-free single-molecule analysis technology that measures molecular mass directly in solution. The product line includes the flagship TwoMP mass photometer for general molecular mass measurements (30 kDa to 5 MDa), the compact MyMassMP for rapid sample quality checks in structural biology, the SamuxMP optimized for AAV characterization with automated version available, and the KaritroMP for macro mass photometry of larger viral vectors (AdV, LVV). Supporting the instruments is a comprehensive software suite (AcquireMP, DiscoverMP, EvaluateMPS, ManageMP) including GMP-compliant options, and a range of specialized consumables including MassGlass sample prep kits, MassFerence calibrants for different applications, and alignment kits. The platform is complemented by the MassFluidix HC microfluidics add-on for concentrated sample analysis.
Differentiator
Problem solved
Functional benefit
Brands
- TwoMP: Flagship mass photometer for high-fidelity measurements of molecular mass for proteins and nucleic acids
- MyMassMP
- SamuxMP
- KaritroMP
- MassFluidix HC
- Refeynery
- MassGlass
- MassFerence
- SizeFerence
- AcquireMP
- DiscoverMP
- ManageMP
- EvaluateMPS
Products and services
- TwoMP Mass Photometer
- MyMassMP Mass Photometer
- SamuxMP Mass Photometer
- KaritroMP Macro Mass Photometer
- MassFluidix HC System
- SamuxMP GMP Software Package
- icIEF–Mass Photometry Integrated Bispecific Antibody Workflow
- MassFerence P2 Calibrant
- MassFerence P1 Calibrant
- SizeFerence Calibrant
- MassGlass UC Sample Prep Kit
- MassGlass NA Sample Prep Kit
Quantifiable outcome
- Results in 1-5 minutes vs hours/days for traditional methods
- +5 more outcomes
Companies that use Refeyn
Customer profileNamed customers4 records
Segments6 records
Ideal customer profiles5 records
Refeyn technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature8 records
Refeyn partnerships and signals
Strategic signalPartnerships
Five partnerships are on record, tiered core.
- Bio-Techne CorporationcoreFirst-of-its-kind integrated workflow combining Bio-Techne's MauriceFlex icIEF system with Refeyn's TwoMP mass photometry platform. The four-hour workflow enables single-molecule resolution analysis of bispecific antibodies and biosimilars, correlating charge heterogeneity with molecular weight and aggregation using nanogram-level samples. Demonstrated using Mosunetuzumab-axgb and a biosimilar, with findings to be presented at ASMS conference.
- Rentschler BiopharmacoreCollaborative project developing digital twins and process analytical technologies with automated predictive process control for AAV manufacturing. Part of CGT Catapult initiative to standardize and scale AAV manufacturing for systemic diseases.
- CGT CatapultcoreUK-based advanced therapy manufacturing organization leading initiative to optimize AAV manufacturing. Refeyn contributing process analytical technologies for automated predictive process control in two-year collaborative project.
- Pharmaron BiologicscoreParticipating in two-year collaborative project with CGT Catapult and Complement Therapeutics intensifying perfusion processes to standardize and scale AAV manufacturing for systemic diseases.
- Complement TherapeuticscoreParticipating in two-year collaborative project with CGT Catapult and Pharmaron Biologics intensifying perfusion processes to standardize and scale AAV manufacturing.
Scale indicators3 records
Recent moves6 records
Expansion highlights6 records
Refeyn competitors and assessment
Company assessmentBroad incumbents
- Malvern Panalytical: Part of Spectris plc, Malvern Panalytical is a leading manufacturer of analytical instruments for particle size, molecular weight, and biomolecular characterization, including Zetasizer (DLS), SEC-MALS (OMNISEC), and microcalorimetry. It is the most directly comparable incumbent to Refeyn's biomolecular mass/particle analysis offering, with deep biopharma penetration and global service.
- Thermo Fisher Scientific: Thermo Fisher is the largest analytical instrument manufacturer globally, with mass spectrometry, chromatography, and biopharma QC product lines that intersect Refeyn's value proposition across protein characterization, AAV analytics, and GMP-compliant software.
- Agilent Technologies: Agilent offers a broad analytical instrument portfolio covering chromatography, mass spectrometry, and cell analysis. It serves biopharma QC and biophysical characterization use cases that overlap with Refeyn's instrument-and-consumables model.
- Waters Corporation: Waters is a leading provider of liquid chromatography, mass spectrometry, and informatics for biopharmaceutical characterization, directly overlapping with Refeyn's protein, antibody, and AAV analytical workflows.
- Sartorius AG: Sartorius offers bioprocess and analytics solutions for cell and gene therapy, including AAV/LV production and analytical tools. Its CellGenie and PAT portfolio targets many of the same CGT manufacturing customers as Refeyn's SamuxMP and KaritroMP.
- Bruker Corporation: Bruker provides high-resolution mass spectrometry and biophysical characterization tools used in structural biology, proteomics, and biopharma QC — directly comparable to Refeyn's TwoMP and MyMassMP value proposition in academic and industrial biophysics labs.
- Cytiva (Danaher): Cytiva provides bioprocess and analytical solutions for the cell and gene therapy industry, including AAV manufacturing platforms and analytical technologies. It overlaps with Refeyn's CGT customer base and process analytics positioning, including the CGT Catapult partnership ecosystem.
- Shimadzu Scientific Instruments: Shimadzu manufactures a broad range of analytical and measurement instruments including mass spectrometry, chromatography, and spectroscopy systems serving biopharmaceutical and life science markets comparable to Refeyn's installed base.
Direct peers
- Wyatt Technology: Wyatt Technology is the dominant provider of multi-angle light scattering (MALS) instrumentation used alongside SEC for absolute molecular weight determination of proteins, nucleic acids, and AAV/LV capsids. It competes most directly with Refeyn's mass photometry value proposition in protein and AAV characterization workflows.
- Unchained Labs: Unchained Labs provides purpose-built analytical tools for biologics formulation, stability, and biophysical characterization. It overlaps directly with Refeyn's protein, antibody, and gene therapy analytical use cases, particularly for bench-top biophysics labs in pharma and biotech.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights6 records
Customer concentration
Refeyn social profiles
Digital presenceRefeyn compliance and trust
Trust signalCompliance2 records
Refeyn financial estimates
Financial estimateRevenue estimate
Valuation estimate
Refeyn leadership team
Management profileNumber of profiles
Profiles6 records
Refeyn funding detail
Funding detailFunding overview
Funding rounds2 records
Investors6 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Refeyn M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Refeyn
What does Refeyn do?
Refeyn manufactures and sells benchtop mass photometry instruments that measure the molecular mass of individual proteins, nucleic acids, AAV capsids, and large viral vectors in solution without labels, returning results in 1–5 minutes from nanogram-scale samples. The portfolio includes the TwoMP (general molecular mass), MyMassMP (structural biology QC), SamuxMP (AAV characterization), and KaritroMP (large viral vectors), supported by a consumables line (MassGlass prep kits, MassFerence/SizeFerence calibrants) and a GMP-compliant software suite for regulated biopharma environments.
Is Refeyn a public or private company?
Refeyn is a private company. It is classified as venture growth investor backed and is currently operating.
When was Refeyn founded?
Refeyn was founded in 2018. It employs 101 to 250 people.
Where is Refeyn based?
Refeyn is headquartered in Oxford, United Kingdom, in the Europe region.
How does Refeyn make money?
Four revenue lines are on record. Mass Photometry Instruments are the primary driver. The others are consumables, service Contracts and Support and software Licenses.
Who are Refeyn's main competitors?
Broad incumbents on record are Malvern Panalytical, Thermo Fisher Scientific, Agilent Technologies, Waters Corporation, Sartorius AG, Bruker Corporation, Cytiva (Danaher) and Shimadzu Scientific Instruments. Direct peers are Wyatt Technology and Unchained Labs.
Does Refeyn have an API?
No public API is recorded for Refeyn.
What industry is Refeyn in?
Refeyn's product category is Analytical Laboratory Instruments. Its primary akta.pro industry code is HLAGAIAB, Mass Spectrometry & Spectroscopy Instruments, with a secondary code of HLAGAIAA, Analytical Instruments & Chromatography Systems. Its NAICS code is 334516 and its SIC code is 3826.