Catalyst OrthoScience
Catalyst OrthoScience is a private US medical device company founded in 2014 that develops and commercializes canal-sparing shoulder arthroplasty implant systems, including anatomic, reverse, fracture, and stemmed platforms, serving orthopedic surgeons and hospitals/ASCs through a direct domestic sales model.
- Company typePrivate
- Founded2014
- HeadquartersNaples, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Catalyst OrthoScience does
Catalyst OrthoScience is a private medical device company founded in 2014 and headquartered in Naples, Florida that develops and commercializes shoulder arthroplasty implant systems. The company positions itself as a pure-play shoulder specialist offering a four-system portfolio covering the full shoulder replacement procedure spectrum: the stem-free Catalyst CSR Total Shoulder System (anatomic), the Catalyst Reverse Shoulder System (R1), the Catalyst Fracture Shoulder System (proximal humeral fractures), and the Catalyst Stemmed Anatomic Shoulder System. Its core technical differentiators include canal-sparing (stem-free and short-stem) implant designs, a proprietary non-spherical ellipsoid humeral head intended to replicate native anatomy, a patented multiplanar osteotomy technique, and a Plunge Reamer with automatic depth stop. The company also markets the Archer 3D Targeting Software for preoperative planning and the FDA-cleared Archer Patient-Specific Instrumentation (PSI) developed with Belgian partner 3D-Side, and claims to be the first and only company offering a single-tray portfolio spanning anatomic, reverse, and fracture procedures.
The company generates revenue through hardware sales of its implant systems and associated instruments to hospitals and ambulatory surgery centers (ASCs), supplemented by medical education services delivered through its seven-location Surgeon-to-Surgeon S.I.T.E. training program, webinars, and recorded surgical procedures. Distribution is exclusively domestic (United States) through direct field sales targeting orthopedic surgeons specializing in shoulder procedures, with contract-negotiated (non-public) implant pricing. Primary customers are orthopedic surgeons and the healthcare facilities where they practice, with secondary end-beneficiaries being patients suffering from shoulder arthritis, trauma, or fracture conditions. Catalyst reports cumulative clinical experience exceeding 10,000 shoulder arthroplasty procedures as of September 2024, with published 5-8 year outcome data on 206 shoulders, and holds over 50 issued or pending patents including US Patent D1,048,403 for tuberosity retention rails.
The business is venture-backed, having raised approximately $70 million+ across multiple rounds from 2016 through 2025, with lead investors including RC Capital, Mutual Capital Partners, and River Cities Capital. The company maintains 11-50 employees, is led by CEO Carl O'Connell, and has professionalized its leadership since 2024 with new CCO, CMO, and senior board appointments (including industry veterans from Johnson & Johnson, Tornier, Stryker, and Wright Medical). Recent strategic activity includes FDA 510(k) clearances for the Archer PSI system (February 2026) and expanded Fracture Shoulder System indications (December 2025), positioning Catalyst for portfolio expansion within the shoulder arthroplasty specialty.
Catalyst OrthoScience firmographics
Firmographics- Name
- Catalyst OrthoScience
- Legal name
- Catalyst OrthoScience Inc.
- Website
- https://catalystortho.com
- Company type
- Private
- Founded year
- 2014
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Catalyst OrthoScience is a private US medical device company founded in 2014 that develops and commercializes canal-sparing shoulder arthroplasty implant systems, including anatomic, reverse, fracture, and stemmed platforms, serving orthopedic surgeons and hospitals/ASCs through a direct domestic sales model.
- Ownership category
- akta.pro rank
Catalyst OrthoScience industry classification
Industry- Product category
- Shoulder Arthroplasty Medical Devices
- NAICS
- Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112)
- SIC
- Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841)
- akta.pro primary industry
- Orthopedic Joint Reconstruction Implants (Hip/Knee/Shoulder/Elbow/Ankle) (HLAHAEAA)
- akta.pro secondary industries
- Surgical Navigation, Robotics & Patient-Matched Instrumentation (Ortho/Spine) (HLAHAEAL), 3D-Printed & Patient-Specific Implants (Custom Ortho/Spine/Cranial) (HLAHAEAJ)
Keywords
Where Catalyst OrthoScience is headquartered
LocationHeadquarters
- HQ city
- Naples
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Catalyst OrthoScience business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Supply Chain, Personnel, Technology or R&D, Marketing or Sales, Operations
Revenue model
- Medical Device Sales - Shoulder Implant Systems: Catalyst OrthoScience generates revenue through the sale of its proprietary shoulder arthroplasty implant systems, including the CSR Total Shoulder System, Reverse Shoulder System, Fracture Shoulder System, and Stemmed Anatomic Shoulder System. Products are sold to hospitals, ambulatory surgery centers (ASCs), and directly to orthopedic surgeons. The company also sells associated instruments, instrumentation sets, and accessory products such as the Tuberosity Repair Kit.
- Medical Education Services: The company provides medical education programs including the Surgeon-to-Surgeon S.I.T.E. program, virtual learning sessions, webinars, recorded surgical procedures, and journal reviews. These programs serve both as revenue-generating services and as GTM tools to drive product adoption.
Go-to-market motion2 records
Distribution channels1 record
Marketing channels7 records
Catalyst OrthoScience product offering
Product offeringCore offering
Catalyst OrthoScience designs, develops, and commercializes proprietary shoulder arthroplasty implant systems — including the stem-free CSR Total Shoulder System, Reverse Shoulder System, Fracture Shoulder System, and Stemmed Anatomic — for hospitals, ambulatory surgery centers, and orthopedic surgeons performing anatomic, reverse, and fracture shoulder replacement procedures. The portfolio is complemented by the Archer 3D Targeting Software for preoperative planning and the FDA-cleared Archer Patient-Specific Instrumentation (PSI) for surgical execution.
Product overview
Catalyst OrthoScience is a medical technology company specializing in shoulder arthroplasty, offering a portfolio of implant systems designed around four core principles: precision placement, anatomic design, bone preservation, and tissue sparing. The product portfolio centers on five main systems: (1) the Catalyst CSR Total Shoulder System - a stem-free anatomic system featuring an elliptical humeral head and multiplanar osteotomy; (2) the Catalyst Reverse Shoulder System - a single-tray reverse arthroplasty system with bone-sparing inlay stem design; (3) the Catalyst Fracture Shoulder System - specifically designed for proximal humeral fractures with tuberosity management features; (4) the Catalyst Stemmed Anatomic Shoulder System - the company's first stemmed system with convertible capability; and (5) the Archer digital health ecosystem - comprising 3D Targeting Software for preoperative planning and Patient-Specific Instrumentation (PSI) for precise intraoperative execution. The company positions itself as a 'pure play shoulder company' focused exclusively on advancing shoulder arthroplasty through surgeon-focused innovation and procedural efficiency, claiming to be the first and only company offering a single-tray portfolio for anatomic, reverse, and fracture procedures.
Differentiator
Problem solved
Functional benefit
Brands
- Catalyst CSR Total Shoulder System: Anatomic shoulder system with elliptical humeral head design for more natural shoulder replacement.
- Catalyst Reverse Shoulder System
- Catalyst Fracture Shoulder System
- Catalyst Stemmed Anatomic
- Archer 3D Targeting Software
Products and services
- Catalyst CSR Total Shoulder System A stem-free anatomic total shoulder arthroplasty system featuring an elliptical (non-spherical) humeral head designed to replicate native anatomy, with patented multiplanar osteotomy for bone preservation, the Plunge Reamer for automatic depth-controlled preparation, and tissue-sparing instrumentation enabling a subscapularis-sparing surgical approach; targeted at orthopedic surgeons performing anatomic shoulder replacement in hospitals and ambulatory surgery centers.
- Catalyst Reverse Shoulder System (R1) A reverse shoulder arthroplasty system with a 139-degree metaphyseal-fitting bone-sparing inlay humeral stem, glenosphere options of 32, 36, and 40mm with up to 10mm lateralization, poly inserts with 0–16mm offset, and single-tray instrumentation that reduces surgical steps by up to 46% compared with competitive reverse systems; intended for orthopedic surgeons performing reverse shoulder replacement in hospitals and ASCs.
- Catalyst Fracture Shoulder System A fracture-specific reverse shoulder arthroplasty system for proximal humeral fractures featuring a tuberosity-specific fossa, patented Tuberosity Retention Rails (US Patent D1,048,403), 135-degree anatomic neck-shaft angle, and press-fit diaphyseal fixation, with FDA 510(k) clearance for expanded anatomic indications; intended for orthopedic surgeons managing proximal humeral fractures in hospitals and ASCs.
- Catalyst Stemmed Anatomic Shoulder System The first stemmed total shoulder arthroplasty system with an elliptical humeral head, allowing conversion between anatomic hemi-arthroplasty and reverse humerus without stem removal, and compatible with the 3-peg glenoid and Catalyst humeral stems in 36mm and 41mm diameters with short and long options; targeted at orthopedic surgeons needing a convertible stemmed option.
- Archer 3D Targeting Software Preoperative shoulder planning software encompassing both anatomic and reverse planning capabilities; creates interactive 3D renderings from patient imaging and delivers personalized surgical plans with individualized implant sizing and placement determination for orthopedic surgeons planning shoulder arthroplasty.
- Archer Patient-Specific Instrumentation (PSI) FDA 510(k)-cleared patient-specific instrumentation providing a full suite of humeral and glenoid guides tailored to individual patient anatomy, developed in partnership with Belgian medtech company 3D-Side, enabling orthopedic surgeons to translate 3D preoperative plans into the OR with greater precision and reduced procedural steps; intended for shoulder arthroplasty cases where preoperative Catalyst Archer plans are used.
Quantifiable outcome
- Preserves up to 50% more healthy bone compared to other stemless designs through patented multiplanar osteotomy
- +6 more outcomes
Companies that use Catalyst OrthoScience
Customer profileNamed customers3 records
Segments3 records
Ideal customer profiles3 records
Catalyst OrthoScience technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration1 record
Feature7 records
Catalyst OrthoScience partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- 3D-SidecoreBelgian medtech company 3D-Side partnered with Catalyst to develop the Archer Patient-Specific Instrumentation (PSI) system. The PSI enables orthopedic surgeons to execute 3D preoperative plans with greater precision and reduced procedural steps. FDA 510(k) clearance received February 2026.
Scale indicators8 records
Recent moves6 records
Expansion highlights6 records
Catalyst OrthoScience competitors and assessment
Company assessmentBroad incumbents
- Stryker: Global orthopedic giant with a comprehensive shoulder arthroplasty portfolio (anchored by the Wright Medical shoulder franchise). Directly competes with Catalyst across anatomic, reverse, and fracture shoulder systems but operates at vastly greater scale with broader joint reconstruction coverage.
- Zimmer Biomet: One of the largest orthopedic device companies with a long-standing shoulder arthroplasty offering (including the Comprehensive and Sidus systems). Competes across the full shoulder procedure spectrum and has a global commercial footprint that Catalyst lacks.
- Johnson & Johnson (DePuy Synthes): Through DePuy Synthes Mitek Sports Medicine, J&J offers the GLOBAL UNITE and other shoulder arthroplasty systems. A broad incumbent with the resources to develop stemless / patient-matched technologies that could compete with Catalyst's canal-sparing approach.
- Smith+Nephew: Orthopedic and sports medicine major with a focused shoulder portfolio including the AEQUALIS family of anatomic, reverse, and fracture shoulder systems. Closely comparable in shoulder-segment specialization though with broader portfolio diversification.
- Enovis (DJO Surgical): DJO Surgical (now part of Enovis) offers the AltiVate and EMPOWR shoulder arthroplasty systems. A relevant peer in shoulder reconstruction with overlapping anatomic and reverse product lines and similar mid-size orthopedic challenger dynamics.
- Arthrex: Privately held orthopedic and sports medicine leader with a growing shoulder arthroplasty portfolio (Univers Revers, Eclipse stemless). Comparable in being a private, innovation-focused orthopedic company with strong surgeon education and training capabilities.
- Tornier (now part of Stryker): Legacy shoulder-focused orthopedic company acquired by Wright Medical and then Stryker; historically a direct peer in stemless and reverse shoulder, now part of the broader Stryker portfolio.
Direct peers
- Exactech: Private shoulder and orthopedic implant company (acquired by TPG then reverted to private under PE ownership) offering the Equinoxe platform — one of the fastest-growing shoulder systems in the US and the closest direct peer to Catalyst in terms of size, focus, and growth profile.
Emerging players
- Materialise: Belgian 3D-printing and patient-specific instrumentation provider with orthopedic planning software and PSI capabilities. Closely comparable to Catalyst's 3D-Side partnership for Archer PSI and operates as an enabling technology partner in shoulder and joint reconstruction.
Others
- Brainlab: Digital surgery and surgical navigation company with growing orthopedic software and patient-specific planning offerings. Adjacent peer where Catalyst's Archer 3D Targeting Software competes for surgeon mind-share in preoperative planning workflows.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Catalyst OrthoScience social profiles
Digital presenceCatalyst OrthoScience financial estimates
Financial estimateRevenue estimate
Valuation estimate
Catalyst OrthoScience leadership team
Management profileNumber of profiles
Profiles8 records
Catalyst OrthoScience funding detail
Funding detailFunding overview
Funding rounds11 records
Investors6 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Catalyst OrthoScience M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Catalyst OrthoScience
What does Catalyst OrthoScience do?
Catalyst OrthoScience designs, develops, and commercializes proprietary shoulder arthroplasty implant systems — including the stem-free CSR Total Shoulder System, Reverse Shoulder System, Fracture Shoulder System, and Stemmed Anatomic — for hospitals, ambulatory surgery centers, and orthopedic surgeons performing anatomic, reverse, and fracture shoulder replacement procedures. The portfolio is complemented by the Archer 3D Targeting Software for preoperative planning and the FDA-cleared Archer Patient-Specific Instrumentation (PSI) for surgical execution.
Is Catalyst OrthoScience a public or private company?
Catalyst OrthoScience is a private company. It is classified as venture growth investor backed and is currently operating.
When was Catalyst OrthoScience founded?
Catalyst OrthoScience was founded in 2014. It employs 11 to 50 people.
Where is Catalyst OrthoScience based?
Catalyst OrthoScience is headquartered in Naples, United States, in the North America region.
How does Catalyst OrthoScience make money?
Two revenue lines are on record. Medical Device Sales - Shoulder Implant Systems are the primary driver. The others are medical Education Services.
Who are Catalyst OrthoScience's main competitors?
Broad incumbents on record are Stryker, Zimmer Biomet, Johnson & Johnson (DePuy Synthes), Smith+Nephew, Enovis (DJO Surgical), Arthrex and Tornier (now part of Stryker). Exactech is listed as a direct peer. Materialise is listed as an emerging player. Brainlab is listed as an others.
Does Catalyst OrthoScience have an API?
No public API is recorded for Catalyst OrthoScience.
What industry is Catalyst OrthoScience in?
Catalyst OrthoScience's product category is Shoulder Arthroplasty Medical Devices. Its primary akta.pro industry code is HLAHAEAA, Orthopedic Joint Reconstruction Implants (Hip/Knee/Shoulder/Elbow/Ankle), with a secondary code of HLAHAEAL, Surgical Navigation, Robotics & Patient-Matched Instrumentation (Ortho/Spine). Its NAICS code is 339113 and its SIC code is 3842.