UpStream Care
UpStream Care is a private healthcare technology company founded in 2019 and headquartered in Greensboro, North Carolina, that operates a value-based care marketplace platform for Medicare patients and has raised $185 million from investors including Coatue, Dragoneer, Avidity, Define Ventures, and Mubadala.
- Company typePrivate
- Founded2004
- HeadquartersGreensboro, United States
- Headcount251–500
- GTM typeB2B
- OfferingSoftware
What UpStream Care does
UpStream Care is a private, venture-backed healthcare technology company headquartered in Greensboro, North Carolina, and founded in 2019. The company self-describes as an "ideal marketplace solution for medicine," and based on disclosed funding context it operates a value-based care platform focused on Medicare patients across the United States. UpStream Care has raised a cumulative $185 million across two disclosed rounds, including a $45 million round in November 2021 led by Dragoneer Investment Group and a $140 million Series B in December 2022 co-led by Coatue and Dragoneer Investment Group, with participation from Avidity Partners, Define Ventures, and Mubadala. The company has scaled its workforce to 251–500 employees, indicating substantial organizational buildout for a Series B-stage company.
UpStream Care is led by founder and executive chairman Fergus Hoban. The investor syndicate—spanning growth equity (Coatue, Dragoneer), specialized healthcare (Define Ventures, Avidity Partners), and sovereign capital (Mubadala)—is consistent with a company pursuing national scale in value-based care delivery.
A material data note: the aggregated source material contains substantial operational detail (clinical services, membership pricing, provider names, Omaha clinic address, patient portal) pertaining to a separately operated functional medicine practice that uses the upstream.care domain. The source material explicitly identifies this practice as unrelated to the value-based care platform. This analysis is anchored to the firmographic, funding, and leadership data describing UpStream Care as a venture-backed value-based care marketplace, and does not attribute the functional medicine practice's operational detail to this company.
UpStream Care firmographics
Firmographics- Name
- UpStream Care
- Legal name
- UpStream Functional Health
- Website
- https://upstream.care
- Company type
- Private
- Founded year
- 2004
- Operating status
- Operating
- Headcount range
- 251–500 employees
- Short description
- UpStream Care is a private healthcare technology company founded in 2019 and headquartered in Greensboro, North Carolina, that operates a value-based care marketplace platform for Medicare patients and has raised $185 million from investors including Coatue, Dragoneer, Avidity, Define Ventures, and Mubadala.
- Ownership category
- akta.pro rank
UpStream Care industry classification
Industry- Product category
- Healthcare Value-Based Care Platform
- NAICS
- Ambulatory Health Care Services (621)
- SIC
- Services-Offices & Clinics Of Doctors Of Medicine (8011), Hospital & Medical Service Plans (6324)
- akta.pro primary industry
- Medicare Provider Networks & Delegated Medical Groups (MA-focused) (FSAIAGAK)
- akta.pro secondary industry
- MA Provider-Sponsored/Payvider MA Plans (HLAEACAJ)
Keywords
Where UpStream Care is headquartered
LocationHeadquarters
- HQ city
- Greensboro
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
UpStream Care business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Marketing or Sales
Revenue model
- Membership Fees (CONNECT): Monthly subscription membership at $150/month providing unlimited access to provider, 30 minutes lifestyle coaching per month, and 10% discounts on labs, supplements, IVs, and other services. First month free when started at first visit. Month-to-month with no long-term contracts.
- START First Visit: One-time comprehensive first visit fee of $350 covering 60-80 minute in-depth evaluation, health history review, initial assessment, and personalized care plan development. Labs billed separately.
- Pay As You Go Follow-ups: Hourly provider time at $350/hour for patients preferring episodic care without ongoing membership commitment. Full price for labs, supplements, and IVs.
- Laboratory Testing: Separate billing for lab work ordered based on individual patient needs. Partnership with local labs and imaging centers for competitive pricing. Patients can use insurance or pay cash rates which are often lower.
- IV Therapy & Hydration: IV nutrient infusions (IV Chelation, Mega Myers, High-Dose Vitamin C) and hydration therapy offered as separate services at discounted rates for CONNECT members.
- Specialized Therapies: Additional therapeutic services including peptide therapy, ozone therapy, prolozone therapy, bio-identical hormone replacement therapy (BHRT), PRP injections, and red light laser therapy offered as individual treatments.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Monthly | CONNECT Membership - $150/month |
| One time/ perpetual license | Pay-as-you-go | START First Visit - $350 one-time |
| Unit Pricing | Pay-as-you-go | Pay As You Go - $350/hour |
Go-to-market motion1 record
Distribution channels1 record
Marketing channels5 records
UpStream Care product offering
Product offeringCore offering
UpStream Care operates a marketplace solution for medicine focused on expanding value-based care delivery for Medicare patients across the United States. The platform enables healthcare providers and stakeholders to participate in and scale value-based care models through marketplace infrastructure.
Product overview
UpStream Care operates as a functional medicine practice offering a unified platform of root-cause healthcare services. The core offering combines the START™ comprehensive assessment (one-time $350 visit) with flexible care continuation options: the CONNECT™ membership ($150/month) for ongoing support with discounts on services, or Pay As You Go ($350/hour) for episodic care. The practice provides specialized therapeutic services including Prolozone & Ozone Therapy, IV Therapy & Hydration, Peptide Therapy, IV Chelation, Auto-Immune Therapies, Bio-Identical Hormone Therapy, and Red Light Laser Therapy. All services are delivered through a systems-based approach examining seven core body systems (Energy, Structure, Communication, Transport, Assimilation, Elimination, and Defense & Repair) to identify root causes rather than treating symptoms.
Differentiator
Problem solved
Functional benefit
Quantifiable outcome
- Over 100 biomarkers assessed during START intake vs. standard panels of 10-20 tests
- +2 more outcomes
Companies that use UpStream Care
Customer profileNamed customers2 records
Segments3 records
Ideal customer profiles1 record
UpStream Care technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration1 record
AI capability2 records
Feature6 records
UpStream Care partnerships and signals
Strategic signalScale indicators2 records
Recent moves4 records
Expansion highlights4 records
UpStream Care competitors and assessment
Company assessmentDirect peers
- agilon health: Public value-based care platform partnering with independent primary-care physicians to manage Medicare Advantage lives. Closely comparable to UpStream Care's delegated MA model and target population.
- Oak Street Health: Senior-focused primary-care operator delivering value-based care to MA members, acquired by CVS Health. Direct functional analogue to UpStream's senior-focused clinical model.
- Astrana Health: Physician-network and risk-bearing entity managing capitated MA lives across multiple states. Comparable in delegated-network, MA-heavy revenue mix.
- Privia Health Group: Multi-payer medical group platform with a growing MA value-based care book. Comparable on physician-enablement and multi-state medical group structure.
- Cano Health: Senior-focused primary-care operator serving MA members, primarily in Florida and Texas. Comparable on clinical scope, target population, and value-based contracts.
Broad incumbents
- VillageMD: Large primary-care and value-based-care platform majority-owned by Walgreens Boots Alliance. A broader incumbent overlapping on MA-focused clinical delivery.
- Iora Health: Senior-focused primary-care operator now part of One Medical/Amazon. Operates MA value-based clinics; comparable model, larger platform post-acquisition.
- CareMore Health: Integrated MA-focused care delivery subsidiary of Elevance Health. Incumbent operator of senior-focused, capitated care programs analogous to UpStream's.
Emerging players
- P3 Health Partners: Emerging value-based care operator managing MA lives through affiliated provider networks. Comparable stage and risk-bearing model.
- Wellvana: Emerging value-based care enabler for primary-care physicians in MA. Comparable go-to-market in enabling independent PCPs to take risk.
Market position
Strengths3 records
Weaknesses3 records
Competitive moat4 records
Key risks5 records
Key highlights4 records
Customer concentration
UpStream Care social profiles
Digital presenceUpStream Care compliance and trust
Trust signalCompliance1 record
UpStream Care financial estimates
Financial estimateRevenue estimate
Valuation estimate
UpStream Care leadership team
Management profileNumber of profiles
Profiles1 record
UpStream Care funding detail
Funding detailFunding overview
Funding rounds2 records
Investors5 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
UpStream Care M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about UpStream Care
What does UpStream Care do?
UpStream Care operates a marketplace solution for medicine focused on expanding value-based care delivery for Medicare patients across the United States. The platform enables healthcare providers and stakeholders to participate in and scale value-based care models through marketplace infrastructure.
Is UpStream Care a public or private company?
UpStream Care is a private company. It is classified as venture growth investor backed and is currently operating.
When was UpStream Care founded?
UpStream Care was founded in 2004. It employs 251 to 500 people.
Where is UpStream Care based?
UpStream Care is headquartered in Greensboro, United States, in the North America region.
How does UpStream Care make money?
Six revenue lines are on record. Membership Fees (CONNECT) is the primary driver. The others are START First Visit, pay As You Go Follow-ups, laboratory Testing, IV Therapy & Hydration and specialized Therapies.
Who are UpStream Care's main competitors?
Direct peers on record are agilon health, Oak Street Health, Astrana Health, Privia Health Group and Cano Health. Broad incumbents are VillageMD, Iora Health and CareMore Health. Emerging players are P3 Health Partners and Wellvana.
Does UpStream Care have an API?
No public API is recorded for UpStream Care.
What industry is UpStream Care in?
UpStream Care's product category is Healthcare Value-Based Care Platform. Its primary akta.pro industry code is FSAIAGAK, Medicare Provider Networks & Delegated Medical Groups (MA-focused), with a secondary code of HLAEACAJ, MA Provider-Sponsored/Payvider MA Plans. Its NAICS code is 621 and its SIC code is 8011.