OneOncology
OneOncology is a physician-led management services organization platform partnering with 33 independent oncology and urology practices across 350+ US sites, serving one million patients with shared technology, analytics, capital, and clinical research infrastructure.
- Company typePrivate
- Founded2018
- HeadquartersNashville, United States
- Headcount1,001–5,000
- GTM typeB2B
- OfferingServices
What OneOncology does
OneOncology is a physician-led Management Services Organization (MSO) platform that partners with independent oncology, urology, and radiation oncology practices across the United States. Founded in 2018 and headquartered in Nashville, Tennessee, the company aggregates 33 partner practices spanning 350+ sites of care and approximately 2,000 providers serving roughly one million patients. OneOncology enables partner practices to maintain clinical autonomy and physician ownership while gaining access to enterprise-scale technology, capital, operational infrastructure, and clinical resources. The company was acquired by Cencora in early 2026 at a $7.4 billion enterprise value.
The platform comprises multiple integrated modules including OneAnalytics (business intelligence across clinical, operational, and financial data), OneR (clinical research site management organization with 15 active practices running 92 trials in 2025), ProMPT (EMR-nested precision medicine decision support), Oncology Quality Hub (CMS-approved Qualified Clinical Data Registry), ASCO-certified Clinical Pathways, OneCommunity (knowledge sharing), and a recently launched AI strategy layer featuring Agentic AI for prior authorization automation, Databricks-powered RWE analytics, and AI-enabled patient experience capabilities. The technology stack integrates with OncoEMR and is differentiated by domain specialization in oncology rather than horizontal healthcare IT.
OneOncology operates a managed services revenue model through partnership arrangements with physician practices, generating revenue from MSO service agreements customized by practice size and scope. The company does not publicly disclose pricing or revenue figures. Go-to-market is enterprise field sales targeting physician leaders of independent practices seeking operational support and growth capital while preserving clinical autonomy. Key customer segments include independent oncology practices (primary), independent urology practices (post-UUG acquisition), and indirectly the community-based cancer patients served by partner practices across all major US regions.
OneOncology firmographics
Firmographics- Name
- OneOncology
- Legal name
- OneOncology, LLC
- Website
- https://oneoncology.com
- Company type
- Private
- Founded year
- 2018
- Operating status
- Operating
- Headcount range
- 1,001–5,000 employees
- Short description
- OneOncology is a physician-led management services organization platform partnering with 33 independent oncology and urology practices across 350+ US sites, serving one million patients with shared technology, analytics, capital, and clinical research infrastructure.
- Ownership category
- akta.pro rank
OneOncology industry classification
Industry- Product category
- Oncology Practice Management Services
- NAICS
- Offices of Physicians (62111), Ambulatory Health Care Services (621)
- SIC
- Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Specialty Outpatient Facilities, Nec (8093), Services-Health Services (8000)
- akta.pro primary industry
- Ambulatory Oncology Centers (Outpatient Chemo/Radiation) (HLAFABAI)
- akta.pro secondary industries
- Medical Oncology (HLAKAFAB), Primary Care Networks, Groups & MSOs (HLAFAGAE)
Keywords
Where OneOncology is headquartered
LocationHeadquarters
- HQ city
- Nashville
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
OneOncology business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Management Services Organization (MSO): OneOncology operates as an MSO providing non-clinical administrative and management support to independent medical specialty practices, including oncology and urology. Revenue is generated through partnership arrangements with physician practices that maintain clinical autonomy while gaining access to platform resources, technology, capital, and operational support.
Go-to-market motion1 record
Distribution channels1 record
Marketing channels6 records
OneOncology product offering
Product offeringCore offering
OneOncology is a Management Services Organization (MSO) that partners with independent oncology and urology practices to provide non-clinical administrative, operational, technology, capital, and clinical support while physicians retain clinical autonomy. The platform delivers shared technology, analytics, clinical pathways, research network access, pharmacy and laboratory services, and back-office functions to community-based specialty practices across the United States.
Product overview
OneOncology is a physician-led MSO (Management Services Organization) platform for independent medical specialty practices in oncology, urology, and radiation oncology. The platform operates as a unified ecosystem combining the core OneOncology Platform with multiple integrated modules: OneAnalytics for business intelligence, OneR for clinical research management, Oncology Quality Hub for CMS QCDR compliance and MIPS reporting, ProMPT for precision medicine, Pathways for clinical decision support, OneCommunity for knowledge sharing, and OneCouncil for physician governance. The platform also encompasses acquired brands including United Urology Group, Navigating Care (patient portal), and SunState Medical Specialists. AI capabilities are embedded throughout including patient experience automation, fax intelligence, prior authorization automation, and Databricks-powered analytics.
Differentiator
Problem solved
Functional benefit
Brands
- Oncology Quality Hub: CMS-approved Qualified Clinical Data Registry (QCDR) platform that supports partner practices in achieving MIPS performance and quality reporting requirements.
- OneR (OneOncology Research Network)
- SunState Medical Specialists
Products and services
- OneOncology Platform Physician-led national platform providing equity partnership arrangements, clinical resources, technology, capital, and operational support to independent oncology and urology practices while preserving physician clinical autonomy.
- OneAnalytics Analytics platform pulling from multiple systems to measure financial, operational, and clinical performance, providing user-friendly interfaces for physicians and practice leaders to interact with the data warehouse.
- OneR (OneOncology Research Network) Clinical research site management organization providing program management, study start-up, contracts and budgets, regulatory, study operations, research finance, research technology, quality, and network site management for community oncology practices.
- Oncology Quality Hub CMS-approved Qualified Clinical Data Registry providing data-driven insights, clinical quality improvement, value-based care program participation, MIPS performance tracking, and CMS data submission for partner practices.
- ProMPT (Provider Messaging for Precision Therapies) Precision medicine tool nested in the EMR that helps physicians interpret next-generation sequencing results, view patient testing reports, explore matching FDA-approved precision therapy options, and obtain precision medicine team support at point of care.
- Clinical Pathways ASCO-certified clinical decision support tools driving evidence-based standardized care, clinical trial prioritization, adherence tracking, and informing strategic initiatives with payors around prior authorizations and value-based contracts.
- United Urology Group Urology management services organization supporting over 250 providers delivering urology care, genitourinary cancer treatment, radiation oncology, pathology, imaging, and pharmacy services.
- SunState Medical Specialists Multi-specialty physician group (formerly GenesisCare USA) with over 100 physicians across urology, oncology, and surgical specialties at 104 clinics in Florida, providing advanced radiation therapies, in-house pharmacy and laboratory, interventional radiology, theranostics, and diagnostic imaging.
- Navigating Care Patient portal and care management platform supporting integrated patient engagement and care coordination for partner practices.
- OneOncology HIE Integration ONC Health IT certified Health Information Exchange integration supporting EMR data exchange with OncoEMR across healthcare systems.
- AI Strategy Platform AI-powered capabilities including patient experience automation, fax intelligence with EMR integration, agentic AI for drug prior authorization, ProMPT decision analytics, and Databricks-powered data abstraction and clinical trial matching.
Quantifiable outcome
- Research network with 15 practices active, 92 trials activated in 2025, 260% increase in trial accruals
- +2 more outcomes
Companies that use OneOncology
Customer profileNamed customers10 records
Segments3 records
Ideal customer profiles2 records
OneOncology technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration2 records
AI capability7 records
Feature5 records
OneOncology partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core.
- GenesisCare USA (Florida)coreOneOncology acquired GenesisCare USA of Florida and relaunched it as SunState Medical Specialists with 100+ physicians across 104 clinics. The acquisition includes plans for investments in advanced clinical services, technology, and expanding access to specialized care in Florida.
- United Urology Group (UUG)coreUnited Urology Group, a urology management services organization supporting approximately 250 physicians, partnered with OneOncology in October 2024. The partnership aims to improve urology and cancer care, focusing on complex genitourinary cancers including prostate and bladder cancers. UUG operates as a subsidiary of OneOncology, with CEO Ian Wong transitioning to OneOncology COO.
Scale indicators7 records
Recent moves7 records
Expansion highlights6 records
OneOncology competitors and assessment
Company assessmentDirect peers
- Astrana Health (formerly Apollo Medical Holdings): Physician-centric MSO/value-based care platform serving independent primary care and specialty groups with delegated risk arrangements — comparable MSO structure, capital-light partnership model, and value-based care orientation across diverse specialties.
- Agilon Health: Physician-group enablement platform partnering with primary care groups under global capitation; comparable capital-light, MSO-style partnership model providing technology, analytics, and payer contracting infrastructure to independent practices.
- Florida Cancer Specialists & Research Institute: One of the largest independent community oncology practices in the US, also operates its own research institute and has historically pursued vertical integration including in-house pharmacy and lab — a peer model for large-scale community oncology delivery.
- Evolent Health: Specialty care value-based care enabler with explicit oncology, cardiology, and musculoskeletal programs serving independent practices and payers — directly comparable in specialty VBC enablement and clinical pathway infrastructure for oncology.
- The US Oncology Network (McKesson): McKesson subsidiary operating the largest US network of community oncology practices with comparable practice partnership MSO economics, technology stack, clinical pathways, and research services — OneOncology's closest and most direct competitor for both partner practices and pharma research dollars.
- Privia Health Group: Public physician-enablement MSO platform that partners with independent medical groups across specialties to provide technology, analytics, and population health infrastructure — comparable business model of equity-light, MSO-led multi-specialty practice partnership at scale.
Broad incumbents
- Humana / CenterWell: Senior-focused integrated care platform with growing oncology and senior primary care offerings including CenterWell Senior Primary Care and specialty pharmacy — broader incumbent increasingly moving into community oncology and value-based cancer care delivery.
- McKesson Corporation: Owner of US Oncology Network and one of the largest pharma distributors in the US — broad incumbent that competes head-to-head with OneOncology for community oncology practices and offers parallel drug-distribution economics post-OneOncology's Cencora acquisition.
Emerging players
- Thyme Care: Value-based oncology navigation and care management startup partnering with payers and providers to coordinate cancer care — overlaps with OneOncology's patient navigation, care management, and value-based contract strategy on a smaller, earlier-stage scale.
Others
- ION Solutions (Cencora): Cencora subsidiary providing group purchasing, technology, and practice support services to community oncology practices — sits inside OneOncology's parent and represents an adjacent oncology practice enablement ecosystem rather than a head-to-head competitor.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat7 records
Key risks7 records
Key highlights7 records
Customer concentration
OneOncology social profiles
Digital presenceOneOncology compliance and trust
Trust signalCompliance2 records
OneOncology financial estimates
Financial estimateRevenue estimate
Valuation estimate
OneOncology leadership team
Management profileNumber of profiles
Profiles12 records
OneOncology subsidiaries and ownership
Company hierarchySubsidiaries2 records
OneOncology funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
OneOncology M&A and investment
M&A and investmentM&A2 records
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about OneOncology
What does OneOncology do?
OneOncology is a Management Services Organization (MSO) that partners with independent oncology and urology practices to provide non-clinical administrative, operational, technology, capital, and clinical support while physicians retain clinical autonomy. The platform delivers shared technology, analytics, clinical pathways, research network access, pharmacy and laboratory services, and back-office functions to community-based specialty practices across the United States.
Is OneOncology a public or private company?
OneOncology is a private company. It is classified as corporate owned and is currently operating.
When was OneOncology founded?
OneOncology was founded in 2018. It employs 1,001 to 5,000 people.
Where is OneOncology based?
OneOncology is headquartered in Nashville, United States, in the North America region.
How does OneOncology make money?
One revenue line is on record: management Services Organization (MSO).
Who are OneOncology's main competitors?
Direct peers on record are Astrana Health (formerly Apollo Medical Holdings), Agilon Health, Florida Cancer Specialists & Research Institute, Evolent Health, The US Oncology Network (McKesson) and Privia Health Group. Broad incumbents are Humana / CenterWell and McKesson Corporation. Thyme Care is listed as an emerging player. ION Solutions (Cencora) is listed as an others.
Does OneOncology have an API?
No public API is recorded for OneOncology.
What industry is OneOncology in?
OneOncology's product category is Oncology Practice Management Services. Its primary akta.pro industry code is HLAFABAI, Ambulatory Oncology Centers (Outpatient Chemo/Radiation), with a secondary code of HLAKAFAB, Medical Oncology. Its NAICS code is 62111 and its SIC code is 8011.