OneOncology

What OneOncology does

OneOncology is a physician-led Management Services Organization (MSO) platform that partners with independent oncology, urology, and radiation oncology practices across the United States. Founded in 2018 and headquartered in Nashville, Tennessee, the company aggregates 33 partner practices spanning 350+ sites of care and approximately 2,000 providers serving roughly one million patients. OneOncology enables partner practices to maintain clinical autonomy and physician ownership while gaining access to enterprise-scale technology, capital, operational infrastructure, and clinical resources. The company was acquired by Cencora in early 2026 at a $7.4 billion enterprise value.

The platform comprises multiple integrated modules including OneAnalytics (business intelligence across clinical, operational, and financial data), OneR (clinical research site management organization with 15 active practices running 92 trials in 2025), ProMPT (EMR-nested precision medicine decision support), Oncology Quality Hub (CMS-approved Qualified Clinical Data Registry), ASCO-certified Clinical Pathways, OneCommunity (knowledge sharing), and a recently launched AI strategy layer featuring Agentic AI for prior authorization automation, Databricks-powered RWE analytics, and AI-enabled patient experience capabilities. The technology stack integrates with OncoEMR and is differentiated by domain specialization in oncology rather than horizontal healthcare IT.

OneOncology operates a managed services revenue model through partnership arrangements with physician practices, generating revenue from MSO service agreements customized by practice size and scope. The company does not publicly disclose pricing or revenue figures. Go-to-market is enterprise field sales targeting physician leaders of independent practices seeking operational support and growth capital while preserving clinical autonomy. Key customer segments include independent oncology practices (primary), independent urology practices (post-UUG acquisition), and indirectly the community-based cancer patients served by partner practices across all major US regions.

Name

OneOncology

Legal name

OneOncology, LLC

Website

https://oneoncology.com

Company type

Private

Founded year

2018

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

OneOncology is a physician-led management services organization platform partnering with 33 independent oncology and urology practices across 350+ US sites, serving one million patients with shared technology, analytics, capital, and clinical research infrastructure.

Ownership category

akta.pro rank

Product category

Oncology Practice Management Services

NAICS

Offices of Physicians (62111), Ambulatory Health Care Services (621)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Specialty Outpatient Facilities, Nec (8093), Services-Health Services (8000)

akta.pro primary industry

Ambulatory Oncology Centers (Outpatient Chemo/Radiation) (HLAFABAI)

akta.pro secondary industries

Medical Oncology (HLAKAFAB), Primary Care Networks, Groups & MSOs (HLAFAGAE)

Keywords

• Oncology practice management
• Urology practice management
• Clinical decision support
• Medical specialty analytics
• Community oncology network

Headquarters

HQ city

Nashville

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Management Services Organization (MSO): OneOncology operates as an MSO providing non-clinical administrative and management support to independent medical specialty practices, including oncology and urology. Revenue is generated through partnership arrangements with physician practices that maintain clinical autonomy while gaining access to platform resources, technology, capital, and operational support.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels6 records

Core offering

OneOncology is a Management Services Organization (MSO) that partners with independent oncology and urology practices to provide non-clinical administrative, operational, technology, capital, and clinical support while physicians retain clinical autonomy. The platform delivers shared technology, analytics, clinical pathways, research network access, pharmacy and laboratory services, and back-office functions to community-based specialty practices across the United States.

Product overview

OneOncology is a physician-led MSO (Management Services Organization) platform for independent medical specialty practices in oncology, urology, and radiation oncology. The platform operates as a unified ecosystem combining the core OneOncology Platform with multiple integrated modules: OneAnalytics for business intelligence, OneR for clinical research management, Oncology Quality Hub for CMS QCDR compliance and MIPS reporting, ProMPT for precision medicine, Pathways for clinical decision support, OneCommunity for knowledge sharing, and OneCouncil for physician governance. The platform also encompasses acquired brands including United Urology Group, Navigating Care (patient portal), and SunState Medical Specialists. AI capabilities are embedded throughout including patient experience automation, fax intelligence, prior authorization automation, and Databricks-powered analytics.

Differentiator

Problem solved

Functional benefit

Brands

• Oncology Quality Hub: CMS-approved Qualified Clinical Data Registry (QCDR) platform that supports partner practices in achieving MIPS performance and quality reporting requirements.
• OneR (OneOncology Research Network)
• SunState Medical Specialists

Products and services

• OneOncology Platform Physician-led national platform providing equity partnership arrangements, clinical resources, technology, capital, and operational support to independent oncology and urology practices while preserving physician clinical autonomy.
• OneAnalytics Analytics platform pulling from multiple systems to measure financial, operational, and clinical performance, providing user-friendly interfaces for physicians and practice leaders to interact with the data warehouse.
• OneR (OneOncology Research Network) Clinical research site management organization providing program management, study start-up, contracts and budgets, regulatory, study operations, research finance, research technology, quality, and network site management for community oncology practices.
• Oncology Quality Hub CMS-approved Qualified Clinical Data Registry providing data-driven insights, clinical quality improvement, value-based care program participation, MIPS performance tracking, and CMS data submission for partner practices.
• ProMPT (Provider Messaging for Precision Therapies) Precision medicine tool nested in the EMR that helps physicians interpret next-generation sequencing results, view patient testing reports, explore matching FDA-approved precision therapy options, and obtain precision medicine team support at point of care.
• Clinical Pathways ASCO-certified clinical decision support tools driving evidence-based standardized care, clinical trial prioritization, adherence tracking, and informing strategic initiatives with payors around prior authorizations and value-based contracts.
• United Urology Group Urology management services organization supporting over 250 providers delivering urology care, genitourinary cancer treatment, radiation oncology, pathology, imaging, and pharmacy services.
• SunState Medical Specialists Multi-specialty physician group (formerly GenesisCare USA) with over 100 physicians across urology, oncology, and surgical specialties at 104 clinics in Florida, providing advanced radiation therapies, in-house pharmacy and laboratory, interventional radiology, theranostics, and diagnostic imaging.
• Navigating Care Patient portal and care management platform supporting integrated patient engagement and care coordination for partner practices.
• OneOncology HIE Integration ONC Health IT certified Health Information Exchange integration supporting EMR data exchange with OncoEMR across healthcare systems.
• AI Strategy Platform AI-powered capabilities including patient experience automation, fax intelligence with EMR integration, agentic AI for drug prior authorization, ProMPT decision analytics, and Databricks-powered data abstraction and clinical trial matching.

Quantifiable outcome

• Research network with 15 practices active, 92 trials activated in 2025, 260% increase in trial accruals
• +2 more outcomes

Named customers10 records

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration2 records

AI capability7 records

Feature5 records

Partnerships

Two partnerships are on record, tiered core.

• GenesisCare USA (Florida)coreStrategic or Co-development Partner · 8 October 2025OneOncology acquired GenesisCare USA of Florida and relaunched it as SunState Medical Specialists with 100+ physicians across 104 clinics. The acquisition includes plans for investments in advanced clinical services, technology, and expanding access to specialized care in Florida.
• United Urology Group (UUG)coreStrategic or Co-development Partner · 20 August 2024United Urology Group, a urology management services organization supporting approximately 250 physicians, partnered with OneOncology in October 2024. The partnership aims to improve urology and cancer care, focusing on complex genitourinary cancers including prostate and bladder cancers. UUG operates as a subsidiary of OneOncology, with CEO Ian Wong transitioning to OneOncology COO.

Scale indicators7 records

Recent moves7 records

Expansion highlights6 records

Direct peers

• Astrana Health (formerly Apollo Medical Holdings): Physician-centric MSO/value-based care platform serving independent primary care and specialty groups with delegated risk arrangements — comparable MSO structure, capital-light partnership model, and value-based care orientation across diverse specialties.
• Agilon Health: Physician-group enablement platform partnering with primary care groups under global capitation; comparable capital-light, MSO-style partnership model providing technology, analytics, and payer contracting infrastructure to independent practices.
• Florida Cancer Specialists & Research Institute: One of the largest independent community oncology practices in the US, also operates its own research institute and has historically pursued vertical integration including in-house pharmacy and lab — a peer model for large-scale community oncology delivery.
• Evolent Health: Specialty care value-based care enabler with explicit oncology, cardiology, and musculoskeletal programs serving independent practices and payers — directly comparable in specialty VBC enablement and clinical pathway infrastructure for oncology.
• The US Oncology Network (McKesson): McKesson subsidiary operating the largest US network of community oncology practices with comparable practice partnership MSO economics, technology stack, clinical pathways, and research services — OneOncology's closest and most direct competitor for both partner practices and pharma research dollars.
• Privia Health Group: Public physician-enablement MSO platform that partners with independent medical groups across specialties to provide technology, analytics, and population health infrastructure — comparable business model of equity-light, MSO-led multi-specialty practice partnership at scale.

Broad incumbents

• Humana / CenterWell: Senior-focused integrated care platform with growing oncology and senior primary care offerings including CenterWell Senior Primary Care and specialty pharmacy — broader incumbent increasingly moving into community oncology and value-based cancer care delivery.
• McKesson Corporation: Owner of US Oncology Network and one of the largest pharma distributors in the US — broad incumbent that competes head-to-head with OneOncology for community oncology practices and offers parallel drug-distribution economics post-OneOncology's Cencora acquisition.

Emerging players

• Thyme Care: Value-based oncology navigation and care management startup partnering with payers and providers to coordinate cancer care — overlaps with OneOncology's patient navigation, care management, and value-based contract strategy on a smaller, earlier-stage scale.

Others

• ION Solutions (Cencora): Cencora subsidiary providing group purchasing, technology, and practice support services to community oncology practices — sits inside OneOncology's parent and represents an adjacent oncology practice enablement ecosystem rather than a head-to-head competitor.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat7 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xx.com/OneOncology
• LinkedInlinkedin.com/company/oneoncology

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles12 records

Subsidiaries2 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A2 records

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about OneOncology