NewLeaf Symbiotics
NewLeaf Symbiotics develops PPFM-based biological crop inputs — biostimulants and EPA-registered biocontrol products — licensed through more than 100 brand partners to row-crop and specialty-crop growers across the U.S.
- Company typePrivate
- Founded1999
- HeadquartersSt Louis, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What NewLeaf Symbiotics does
NewLeaf Symbiotics is a St. Louis-based agricultural biotechnology company that develops biological crop inputs based on Pink-Pigmented Facultative Methylotrophs (PPFMs) — naturally plant-symbiotic microbes. The company has built a proprietary library of more than 12,000 PPFM strains with over 7,000 sequenced and holds more than 250 patents and patent applications covering biostimulants, biocontrol, nitrogen use efficiency, and methane mitigation. Its commercial portfolio includes EPA-registered bioinsecticides (TS201 for corn, soybean, cotton, and rice) and biofungicides (TS601 for corn, soybeans, cotton, peanuts, and wheat), plus crop-specific Terrasym biostimulants for corn, soybeans, cotton, peanuts, and vegetable transplants, with pipeline technologies in rice methane mitigation and nitrogen fixation.
NewLeaf monetizes through a licensing and royalty model, providing PPFM technology to more than 100 brand partners — including Meristem, AMVAC, Corteva, Nutrien Ag Solutions, Indigo Ag, BW Fusion, AgroTech USA, and others — that incorporate it into products sold to growers. Technologies are applied as planter box treatments, seed treatments, or drenches and have been validated across hundreds of multi-location field trials, demonstrating outcomes such as 8.7-9 bu/A yield advantages in corn and 14.2% tomato yield increases.
The company sells exclusively through distribution partners and agricultural retailers, targeting row-crop growers (corn, soybeans, cotton, peanuts, rice) and specialty-crop growers (tomatoes, cucurbits, peppers, strawberries). The company was founded in 1999, remains privately held, employs 11-50 people, and has raised approximately $132M across multiple funding rounds including a $45M Series D in December 2023 led by Gullspång Re:food with participation from Leaps by Bayer, Otter Capital, and S2G Ventures.
NewLeaf Symbiotics firmographics
Firmographics- Name
- NewLeaf Symbiotics
- Legal name
- NewLeaf Symbiotics, Inc.
- Website
- https://newleafsym.com
- Company type
- Private
- Founded year
- 1999
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- NewLeaf Symbiotics develops PPFM-based biological crop inputs — biostimulants and EPA-registered biocontrol products — licensed through more than 100 brand partners to row-crop and specialty-crop growers across the U.S.
- Ownership category
- akta.pro rank
NewLeaf Symbiotics industry classification
Industry- Product category
- Agricultural Biologicals
- NAICS
- Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (3253), Pesticide and Other Agricultural Chemical Manufacturing (32532)
- SIC
- Agricultural Chemicals (2870)
- akta.pro primary industry
- Biostimulants & Plant Health Biologicals (Microbial/Non-microbial) (AFABAEAK)
- akta.pro secondary industries
- Biofertilizers & Microbial Inoculants (IMAEAEAG), Microbial Biofungicides (AFABAEAB), Soil Health Activators & Biostimulants (Humates, Amino Acids, Seaweed Extracts) (AFABAKAJ)
Keywords
Where NewLeaf Symbiotics is headquartered
LocationHeadquarters
- HQ city
- St Louis
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
NewLeaf Symbiotics business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Operations, Personnel, Marketing or Sales, Infrastructure
Revenue model
- Technology Licensing to Biological Manufacturers: NewLeaf provides its PPFM technologies to biological manufacturers that sell them at the farm gate. Their portfolio offers eight technologies commercially labeled for 10 crops, found in more than 100 brands sold through partners and distributors across the United States.
Go-to-market motion3 records
Distribution channels13 records
Marketing channels9 records
NewLeaf Symbiotics product offering
Product offeringCore offering
NewLeaf Symbiotics develops and commercializes microbial agricultural technologies based on Pink-Pigmented Facultative Methylotrophs (PPFMs). Its commercial offerings include EPA-registered bioinsecticides (TS201 for corn, soybean, cotton, rice), EPA-registered biofungicides (TS601 for corn, soybean, cotton, peanut, wheat), and crop-specific PPFM-powered biostimulants (Terrasym 450 corn, Terrasym 401 soybean, Terrasym 410 cotton, Terrasym 402 peanut, and Terrasym VT vegetable transplant line for tomato, cucurbit, pepper, and strawberry). Technologies are licensed to 100+ agricultural brand partners that distribute finished products to growers.
Product overview
NewLeaf Symbiotics is a biological technology provider and pioneer in Pink-Pigmented Facultative Methylotrophs (PPFMs). The company offers a portfolio of EPA-registered biocontrol products and biostimulant technologies. Core products include two bioinsecticide brands (TS201 for corn, soybean, cotton) and two biofungicide brands (TS601 for corn, soybean, cotton, peanut), plus four crop-specific biostimulant brands (Terrasym 450 for corn, Terrasym 401 for soybean, Terrasym 410 for cotton, Terrasym 402 for peanut). Specialty vegetable transplant technologies under the VT line (for tomato, cucurbit, pepper, strawberry) address transplant stress. The company provides technologies to biological manufacturers for sale at the farm gate through 100+ brands, with eight technologies commercially available for ten crops. Pipeline includes rice technology for yield and methane mitigation, and nitrogen fixation technology.
Differentiator
Problem solved
Functional benefit
Brands
- Terrasym: PPFM-powered biostimulant technology brand for various crops including corn, soybean, cotton, peanut, and vegetable transplants (VT).
- TS201
- TS601
- Pink Performance
Products and services
- TS201 Corn Bioinsecticide EPA-registered PPFM-powered bioinsecticide providing season-long, broad-spectrum protection against corn rootworm, fall armyworm, wireworm, and root knot nematode in corn through induced systemic resistance (ISR).
- TS201 Soybean Bioinsecticide EPA-registered PPFM-powered bioinsecticide providing season-long protection against root knot nematode, soybean looper, and stink bug in soybeans through induced systemic resistance.
- TS201 Cotton Bioinsecticide EPA-registered PPFM-powered bioinsecticide for cotton providing protection against root knot nematode and thrips through induced systemic resistance, often paired with Terrasym 410 biostimulant.
- TS601 Corn Biofungicide EPA-registered PPFM-powered biofungicide that primes corn plants' natural defenses against southern rust, tar spot, and crown rot through induced systemic resistance.
- TS601 Soybean Biofungicide EPA-registered PPFM-powered biofungicide protecting soybeans against sudden death syndrome, white mold, phytophthora, rhizoctonia, and pythium through induced systemic resistance.
- TS601 Cotton Biofungicide EPA-registered PPFM-powered biofungicide for cotton providing protection against fusarium, pythium, and rhizoctonia through induced systemic resistance.
- TS601 Peanut Biofungicide EPA-registered PPFM-powered biofungicide protecting peanuts against white mold, fusarium, pythium, and rhizoctonia through induced systemic resistance.
- Terrasym 450 Corn Biostimulant PPFM-powered biostimulant specifically formulated for corn that improves nutrient uptake, enhances root development, and provides protection against abiotic stress throughout the season. Applied as planter box treatment.
- Terrasym 401 Soybean Biostimulant PPFM-powered biostimulant for soybeans that increases nutrient uptake through siderophore production, provides protection against abiotic stress, and has shown significant impact on iron deficiency chlorosis.
- Terrasym 410 Cotton Biostimulant PPFM-powered biostimulant for cotton providing season-long benefits including increased nutrient uptake and protection against abiotic stress. Available as planter box application.
- Terrasym 402 Peanut Biostimulant PPFM-powered biostimulant for peanuts with rhizobia compatibility that increases plant mass through nutrient uptake and provides season-long protection against abiotic stress.
- Terrasym VT for Tomato PPFM-powered vegetable transplant technology for tomatoes that improves nutrient uptake, mitigates transplant stress, and enhances seedling vigor from transplant to harvest.
- VT for Cucurbit PPFM-powered vegetable transplant technology for cucurbits that helps address transplant stress by colonizing seedlings, offering support from application through harvest with improved performance.
- VT for Pepper PPFM-powered vegetable transplant technology for peppers that helps improve nutrient uptake, boost seedling vigor, and provide resiliency to abiotic stressors including transplant stress.
- VT for Strawberry PPFM-powered vegetable transplant technology for strawberries that supports resiliency to abiotic stressors such as drought or volatile weather, improving plant vigor from seedling to harvest.
Quantifiable outcome
- 8.7-9 bu/A yield advantage in corn with TS201 bioinsecticide
- +9 more outcomes
Companies that use NewLeaf Symbiotics
Customer profileNamed customers11 records
Segments3 records
Ideal customer profiles3 records
NewLeaf Symbiotics technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
NewLeaf Symbiotics partnerships and signals
Strategic signalPartnerships
Six partnerships are on record, tiered core.
- BW FusioncorePartnership to develop BW Defend biological control series utilizing pink-pigmented facultative methylotroph (PPFM) strains. Field trials showed 5.9 bu/acre corn and 3.4 bu/acre soybean yield benefits.
- AgroTech USAcorePartnership to launch PowerPlant PPFM planter box treatment combining AgroTech's NutriCharge phosphorus technology with NewLeaf's PPFM biostimulant technology. Includes option for TS201 corn rootworm protection.
- U.S. Department of Energy Joint Genome InstitutecorePartnership with DOE JGI at Lawrence Berkeley National Laboratory to quantify methane mitigation and nitrogen fixation properties of methanotroph technology in rice. Joint collaboration with Berkeley Lab's Chiniquy, Jardine, and Northen labs using EcoFABs.
- Meristem Crop PerformancecorePartner offering TS201 technology in GUARDX for corn product. Meristem is a crop performance company distributing biological products.
- AMVACcorePartner offering TS201 technology in BioWake Prime bioinsecticide product.
- Low Mu TechcorePartner offering TS201 technology in Terrasym 450+DUST + TS201 CRW product.
Scale indicators22 records
Recent moves8 records
Expansion highlights7 records
NewLeaf Symbiotics competitors and assessment
Company assessmentDirect peers
- AgBiome: AgBiome is a direct peer using a microbial discovery platform to develop biopesticides and biostimulants for row and specialty crops, overlapping directly with NewLeaf's TS201/TS601 biocontrol and Terrasym biostimulant portfolios.
- Sound Agriculture: Sound Agriculture is a direct peer developing microbial and chemistry-based solutions for nutrient efficiency and crop stress, overlapping with NewLeaf's PPFM biostimulants that target nutrient uptake and abiotic stress tolerance.
- Indigo Ag: Indigo Ag is a direct peer offering microbial seed treatments and foliar biologicals for row crops and is also a distribution partner for NewLeaf. It competes head-to-head in the ag biologicals category serving corn, soybean, cotton, and wheat growers with microbially-based products.
- Pivot Bio: Pivot Bio is a direct peer developing microbial nitrogen-fixing products for corn and other cereals. It is comparable to NewLeaf's PPFM nitrogen-fixation pipeline and competes for the same microbial-input channel and row-crop grower mindshare.
- BioConsortia: BioConsortia is a direct peer using microbial consortia discovery to develop biostimulants, biocontrol, and nitrogen-fixation products for row crops, directly comparable to NewLeaf's PPFM-based platform and pipeline.
Broad incumbents
- Bayer Crop Science: Bayer Crop Science is a broad incumbent with a large synthetic crop protection portfolio and a growing biologicals pipeline (and is also a NewLeaf investor via Leaps by Bayer). It anchors the competitive landscape NewLeaf is selling into and partnering with.
- Corteva Agriscience: Corteva is a broad incumbent in crop protection and seeds that both competes with and distributes NewLeaf's technologies. Its biologicals portfolio and existing agronomist channel make it a key comparator for go-to-market and competitive dynamics.
- Syngenta Biologicals: Syngenta Biologicals is the broad incumbent biologicals arm of Syngenta, offering biostimulants, biocontrol, and biopesticides globally. It is comparable as a large, established competitor with overlapping product categories in crop protection and plant health.
Emerging players
- Symborg: Symborg is an emerging player offering microbial biostimulants and biocontrol products for specialty and row crops, comparable to NewLeaf's Terrasym biostimulant and TS601 biofungicide lines targeting similar grower pain points.
- Vestaron: Vestaron is an emerging player developing peptide-based bioinsecticides targeting pests including corn rootworm. It overlaps with NewLeaf's TS201 bioinsecticide positioning as a non-chemical alternative for major row crop pests.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks5 records
Key highlights6 records
Customer concentration
NewLeaf Symbiotics social profiles
Digital presenceNewLeaf Symbiotics financial estimates
Financial estimateRevenue estimate
Valuation estimate
NewLeaf Symbiotics leadership team
Management profileNumber of profiles
Profiles15 records
NewLeaf Symbiotics funding detail
Funding detailFunding overview
Funding rounds7 records
Investors11 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
NewLeaf Symbiotics M&A and investment
M&A and investmentM&A1 record
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about NewLeaf Symbiotics
What does NewLeaf Symbiotics do?
NewLeaf Symbiotics develops and commercializes microbial agricultural technologies based on Pink-Pigmented Facultative Methylotrophs (PPFMs). Its commercial offerings include EPA-registered bioinsecticides (TS201 for corn, soybean, cotton, rice), EPA-registered biofungicides (TS601 for corn, soybean, cotton, peanut, wheat), and crop-specific PPFM-powered biostimulants (Terrasym 450 corn, Terrasym 401 soybean, Terrasym 410 cotton, Terrasym 402 peanut, and Terrasym VT vegetable transplant line for tomato, cucurbit, pepper, and strawberry). Technologies are licensed to 100+ agricultural brand partners that distribute finished products to growers.
Is NewLeaf Symbiotics a public or private company?
NewLeaf Symbiotics is a private company. It is classified as venture growth investor backed and is currently operating.
When was NewLeaf Symbiotics founded?
NewLeaf Symbiotics was founded in 1999. It employs 11 to 50 people.
Where is NewLeaf Symbiotics based?
NewLeaf Symbiotics is headquartered in St Louis, United States, in the North America region.
How does NewLeaf Symbiotics make money?
One revenue line is on record: technology Licensing to Biological Manufacturers.
Who are NewLeaf Symbiotics's main competitors?
Direct peers on record are AgBiome, Sound Agriculture, Indigo Ag, Pivot Bio and BioConsortia. Broad incumbents are Bayer Crop Science, Corteva Agriscience and Syngenta Biologicals. Emerging players are Symborg and Vestaron.
Does NewLeaf Symbiotics have an API?
No public API is recorded for NewLeaf Symbiotics.
What industry is NewLeaf Symbiotics in?
NewLeaf Symbiotics's product category is Agricultural Biologicals. Its primary akta.pro industry code is AFABAEAK, Biostimulants & Plant Health Biologicals (Microbial/Non-microbial), with a secondary code of IMAEAEAG, Biofertilizers & Microbial Inoculants. Its NAICS code is 3253 and its SIC code is 2870.