ReactWise
ReactWise is an AI-driven chemical process optimization platform that uses proprietary multi-task Bayesian optimization (MemoryBO) to help pharmaceutical, biotech, materials science, and fine chemicals R&D teams accelerate reaction development. Founded in 2022 in London, it serves major pharmaceutical companies including Pfizer, Amgen, and Biogen.
- Company typePrivate
- Founded2022
- HeadquartersLondon, United Kingdom
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What ReactWise does
ReactWise is an AI-driven chemical process optimization platform that serves pharmaceutical, biotechnology, materials science, and fine chemicals R&D teams. Founded in 2022 in London, the company has established a US entity (ReactWise Inc.) in San Francisco and operates an R&D laboratory in Cambridge, UK. Its named customer base spans 5 of the top 10 global pharmaceutical companies, with disclosed engagements at Pfizer, Amgen, Biogen, Pharmaron, and On Demand Pharmaceuticals, supported by 12 active pilot studies and new-vertical accounts in materials science (A&B Smart Materials) and fine chemicals (AmarFLO).
The company's core technology combines Bayesian optimization with its proprietary MemoryBO multi-task learning algorithm, pre-trained on more than 25,000 proprietary high-throughput experimentation (HTE) data points. The product portfolio comprises a software optimization platform, HTE Plate Designer, Solvent Selector, HTE Data on Demand, Kinetic Modeling tools, an in-platform AI assistant named Vera, and physical Glass HTE Plates. The platform is designed to integrate with existing laboratory infrastructure and ELN systems, including an established integration partnership with AI4Green, and exposes SHAP-based interpretability to chemists.
ReactWise operates a primarily SaaS-based business model with per-user licensing and annual enterprise contracts, complemented by data monetization through HTE Data on Demand and hardware revenue from Glass HTE Plates. The company is pre-seed stage with $3.4M raised, holds SOC 2 Type 2 (achieved June 2026) and ISO 27001 certifications, and is part of the Y Combinator Summer 2024 batch. Its scientific advisory board includes Klavs Jensen (MIT) and Steven Ley (Cambridge), and the founding team comprises Cambridge-trained PhDs in machine learning and chemistry.
ReactWise firmographics
Firmographics- Name
- ReactWise
- Legal name
- ReactWise Inc.
- Website
- https://reactwise.com
- Company type
- Private
- Founded year
- 2022
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- ReactWise is an AI-driven chemical process optimization platform that uses proprietary multi-task Bayesian optimization (MemoryBO) to help pharmaceutical, biotech, materials science, and fine chemicals R&D teams accelerate reaction development. Founded in 2022 in London, it serves major pharmaceutical companies including Pfizer, Amgen, and Biogen.
- Ownership category
- akta.pro rank
ReactWise industry classification
Industry- Product category
- Chemical Process Optimization Software
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), Custom Computer Programming Services (541511)
- SIC
- Services-Prepackaged Software (7372)
- akta.pro primary industry
- AI/ML Platforms for Drug Discovery & Experiment Optimization (HLAGAJAO)
- akta.pro secondary industry
- End-to-End Enterprise AI Platforms (MLOps & Model Lifecycle Management) (HDAEANAA)
Keywords
Where ReactWise is headquartered
LocationHeadquarters
- HQ city
- London
- HQ country
- United Kingdom
- HQ region
- Europe
Offices3 records
Markets served
ReactWise business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain
Revenue model
- Software Subscription (User Subscriptions): SaaS subscription model based on user seats. Clients purchase user subscriptions that entitle Authorised Users to access the Services. Fees calculated as number of User Subscriptions multiplied by price per User Subscription. Service Capacity of 1,000 experiments per User Subscription per day.
- HTE Data on Demand: Large-scale HTE data generation service to support reactivity models. Generates structured, machine-readable, FAIR datasets in ORD format. Can deliver data as a service or validated production-ready reactivity models.
- Professional Services: Hands-on onboarding, technical documentation, and ongoing support included. Standard and enhanced support fees waived for Subscription Term. Technical team available via email and next-day calls.
- Glass HTE Plates: Physical product: reusable glass well-plates for high throughput experimentation (Borosilicate, Quartz). Compatible with standard 96/384-well plate chemistry equipment. Includes sealing kit.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Per seat | Annual | User Subscription - per seat pricing |
| Subscription | Multi-year contract | Enterprise tier with volume licensing |
Go-to-market motion3 records
Distribution channels5 records
Marketing channels9 records
ReactWise product offering
Product offeringCore offering
ReactWise provides a cloud-based AI software platform for chemical reaction and process optimization, using proprietary multi-task Bayesian optimization (MemoryBO) to recommend experimental conditions and accelerate pharmaceutical and chemical R&D. The platform includes the Optimization Platform, HTE Plate Designer, Solvent Selector, and Kinetic Modeling tools, with optional HTE data-generation services, glass well-plates, and programmable API connectivity to automated laboratory hardware for closed-loop, self-driving workflows.
Product overview
ReactWise is an AI-powered chemical process optimization platform consisting of four core products: the Optimization Platform (Bayesian optimization engine with MemoryBO® transfer learning), HTE Plate Designer (generates machine-readable plate layouts for high-throughput experimentation), Solvent Selector (identifies green solvent replacements using Hansen space analysis), and HTE Data on Demand (large-scale data generation service). The platform is complemented by Glass HTE Plates (reusable laboratory equipment) and Kinetic Modeling capabilities (automated model fitting for scale-up). ReactWise serves pharmaceutical, biotech, and fine chemicals R&D teams, integrating with ELNs, LIMS, and automated laboratory hardware for closed-loop optimization.
Differentiator
Problem solved
Functional benefit
Brands
- MemoryBO: ReactWise's proprietary multi-task Bayesian optimization algorithm that can learn from previous data and transfer learning across related reactions.
Products and services
- Optimization Platform A Bayesian optimization engine with transfer learning capabilities for chemical process development, formulations, and method development. Replaces trial-and-error approaches with data-driven optimization that learns from every experiment.
- HTE Plate Designer Generates structured, machine-readable plate layouts for high-throughput experimentation in 24, 48, 96, or 384-well formats. Provides intelligent plate balancing with automated validation against well budget.
- Solvent Selector Identifies green single and binary mix solvent replacements for toxic or polluting industrial solvents using Hansen space analysis. Shows solvent similarity and greenness trade-offs.
- HTE Data on Demand Large-scale HTE data generation service to support reactivity models. Designs and runs experimental campaigns generating structured, machine-readable, FAIR datasets in ORD format. Includes validated production-ready reactivity models.
- Glass HTE Plates Reusable glass well-plates for high-throughput experimentation made from Borosilicate, Quartz, and other materials. Compatible with industrially relevant solvents like toluene and dioxane that are incompatible with plastic single-use plates. Includes sealing kit.
Quantifiable outcome
- Accelerates chemical process development by 30x, cutting up to 95% of experimental work
- +5 more outcomes
Companies that use ReactWise
Customer profileNamed customers9 records
Segments4 records
Ideal customer profiles4 records
ReactWise technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- Yes
- API docs
- API detail
Core technology
AI maturity
App detail
Integration6 records
AI capability8 records
Feature6 records
ReactWise partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core and minor.
- AI4GreencoreReactWise integrated with AI4Green's electronic lab notebook (ELN) enabling two-way data exchange. Historical ELN data supports MemoryBO and improves future recommendations, while ReactWise data is sent back to the ELN. Reduces manual data handling and links optimization with laboratory records.
- University of Warwick (Polymer Group)minorCollaborative research partnership with University of Warwick polymer group on Henry Royce Institute-funded project for sustainable polymer development using ReactWise optimization platform.
Scale indicators10 records
Recent moves6 records
Expansion highlights6 records
ReactWise competitors and assessment
Company assessmentDirect peers
- Citrine Informatics: AI platform for materials and chemicals R&D using Bayesian optimization and machine learning. Comparable in applying AI/ML to chemistry and materials experimentation, with similar enterprise pharma/chemicals customer base.
- Schrödinger: Public AI-driven molecular simulation and drug discovery platform with materials science and process optimization offerings. Most directly comparable as an AI-for-chemistry software company serving pharma R&D with subscription-based enterprise SaaS.
Broad incumbents
- Insilico Medicine: AI-driven drug discovery company with chemistry optimization capabilities. Comparable in using AI/ML across pharma R&D workflows, though more focused on target identification and lead generation than process chemistry optimization.
- Recursion Pharmaceuticals: Public AI-driven drug discovery company combining high-throughput experimentation with machine learning. Comparable in the AI-for-pharma-R&D category, though focused more on phenotypic screening and target discovery than process optimization.
- Exscientia: Public AI-driven precision medicine company applying ML to drug design and optimization. Overlaps with ReactWise in pharma AI platform positioning, though more focused on small molecule design than chemical process optimization.
- Dotmatics: Enterprise scientific intelligence platform for R&D including ELN, LIMS, and data analysis. Comparable as enterprise software serving pharma/biotech R&D with chemistry workflow integration, though broader in scope than ReactWise's optimization focus.
- IBM RXN: IBM's AI chemistry platform for reaction prediction and retrosynthesis. Overlaps with ReactWise in applying AI to chemical reaction optimization, but as part of IBM's broader R&D portfolio rather than a specialized startup.
Emerging players
- Strateos: Cloud-based automated chemistry and biology lab platform with AI-driven experimental design. Comparable in the self-driving lab category and integration with optimization software for chemistry workflows.
- Emerald Cloud Lab: Remote-controlled automated laboratory platform enabling self-driving experimentation. Comparable in combining AI optimization with closed-loop lab automation, though primarily focuses on general-purpose lab access rather than pharma-specific process optimization.
- Benchling: Cloud-based platform for biotech R&D including ELN, LIMS, and molecular biology tools. Adjacent competitor in pharma R&D software; ReactWise integrates with ELNs like AI4Green that complement Benchling's offerings.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights6 records
Customer concentration
ReactWise social profiles
Digital presenceReactWise compliance and trust
Trust signalCompliance2 records
ReactWise financial estimates
Financial estimateRevenue estimate
Valuation estimate
ReactWise leadership team
Management profileNumber of profiles
Profiles13 records
ReactWise funding detail
Funding detailFunding overview
Funding rounds3 records
Investors2 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
ReactWise M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about ReactWise
What does ReactWise do?
ReactWise provides a cloud-based AI software platform for chemical reaction and process optimization, using proprietary multi-task Bayesian optimization (MemoryBO) to recommend experimental conditions and accelerate pharmaceutical and chemical R&D. The platform includes the Optimization Platform, HTE Plate Designer, Solvent Selector, and Kinetic Modeling tools, with optional HTE data-generation services, glass well-plates, and programmable API connectivity to automated laboratory hardware for closed-loop, self-driving workflows.
Is ReactWise a public or private company?
ReactWise is a private company. It is classified as venture growth investor backed and is currently operating.
When was ReactWise founded?
ReactWise was founded in 2022. It employs 11 to 50 people.
Where is ReactWise based?
ReactWise is headquartered in London, United Kingdom, in the Europe region.
How does ReactWise make money?
Four revenue lines are on record. Software Subscription (User Subscriptions) is the primary driver. The others are HTE Data on Demand, professional Services and glass HTE Plates.
Who are ReactWise's main competitors?
Direct peers on record are Citrine Informatics and Schrödinger. Broad incumbents are Insilico Medicine, Recursion Pharmaceuticals, Exscientia, Dotmatics and IBM RXN. Emerging players are Strateos, Emerald Cloud Lab and Benchling.
Does ReactWise have an API?
Yes. ReactWise offers a fully programmable API that can connect to any automated hardware for closed-loop, real-time optimization. The API enables custom integrations with external software and hardware platforms. Full API documentation is available for clients.
What industry is ReactWise in?
ReactWise's product category is Chemical Process Optimization Software. Its primary akta.pro industry code is HLAGAJAO, AI/ML Platforms for Drug Discovery & Experiment Optimization, with a secondary code of HDAEANAA, End-to-End Enterprise AI Platforms (MLOps & Model Lifecycle Management). Its NAICS code is 541714 and its SIC code is 7372.