YonedaLabs
Yoneda Labs builds AI-driven Bayesian optimization software (Yoneda Predict, Optimize, Analyze) that helps chemists in pharma, chemical manufacturing, and agriculture find optimal reaction conditions in days instead of months, using a proprietary wet-lab robotics data flywheel.
- Company typePrivate
- Founded2023
- HeadquartersSan Francisco, United States
- Headcount1–10
- GTM typeB2B
- OfferingSoftware
What YonedaLabs does
Yoneda Labs Inc. is a San Francisco-based, venture-backed early-stage software company building AI tools that help industrial chemists optimize the conditions of organic chemical reactions. Its product suite is composed of three integrated applications: Yoneda Optimize, a desktop application applying proprietary Bayesian optimization algorithms to find high-yielding reaction conditions in days rather than months; Yoneda Predict, an AI model trained on tens of thousands of experimental data points generated in the company's own wet lab to forecast reliable conditions for novel reactions; and Yoneda Analyze, an automated LCMS spectrum analysis tool that detects, integrates, and visualizes chromatographic peaks.
The company's technical differentiator is a closed-loop data flywheel combining high-throughput experimentation (HTE) robotics with proprietary machine learning models purpose-built for chemistry parameter spaces — including ligand, base, solvent, temperature, and concentration. Benchmarks published by the company claim performance within 3% of optimal yield across Direct Arylation, Suzuki cross-coupling, and Buchwald-Hartwig amination reactions, achieved with roughly 20-40 reactions compared to the 50-60 typically required by expert chemists.
Yoneda Labs operates an enterprise direct-sales motion targeting Big Pharma, chemical manufacturing, and agricultural chemistry customers under a license-based annual subscription with undisclosed custom pricing. The company was founded in 2023 by Michał Mgeładze-Arciuch (CEO), Jan Oboril (Chief Scientist), and Daniel Vlasits (CTO), with advisory support from University of Illinois chemistry professor Scott E. Denmark. It is backed by Khosla Ventures (lead of a $4M seed round in April 2024) and Y Combinator, alongside a syndicate including 468 Capital, Alumni Ventures, e2vc, Fellows Fund, Springboard Health Angels, and Unpopular Ventures. Symeres, a transatlantic CRO/CDMO, was disclosed as the first major commercial case study in May 2025, reporting reaction yield improvements from approximately 30% to over 90% on transition-metal cross-coupling reactions.
YonedaLabs firmographics
Firmographics- Name
- YonedaLabs
- Legal name
- Yoneda Labs Inc.
- Website
- https://yonedalabs.com
- Company type
- Private
- Founded year
- 2023
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- Yoneda Labs builds AI-driven Bayesian optimization software (Yoneda Predict, Optimize, Analyze) that helps chemists in pharma, chemical manufacturing, and agriculture find optimal reaction conditions in days instead of months, using a proprietary wet-lab robotics data flywheel.
- Ownership category
- akta.pro rank
YonedaLabs industry classification
Industry- Product category
- AI Reaction Optimization Software
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516), Chemical Manufacturing (325)
- SIC
- Services-Prepackaged Software (7372), Laboratory Apparatus & Furniture (3821)
- akta.pro primary industry
- AI/ML Platforms for Drug Discovery & Experiment Optimization (HLAGAJAO)
- akta.pro secondary industries
- In Silico / Computational Toxicology & PK/PD Modeling (HLAGAFAM), Crop Protection Formulations (EC, SC, WG, WP, SL) (AFABAIAA), Custom Synthesis & Technical Active Ingredient (AI) Manufacturing (intermediates, actives) (AFABAIAI)
Keywords
Where YonedaLabs is headquartered
LocationHeadquarters
- HQ city
- San Francisco
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
YonedaLabs business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Technology or R&D, Supply Chain, Personnel, Marketing or Sales, Operations, Infrastructure
Revenue model
- Software Licenses: Yoneda Optimize is sold as a desktop application requiring a license code for download and use. The software appears to be distributed as a downloadable product with license-based access.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Annual | Enterprise licensing with custom pricing |
Go-to-market motion1 record
Distribution channels1 record
Marketing channels3 records
YonedaLabs product offering
Product offeringCore offering
YonedaLabs builds AI-powered desktop and cloud software that helps chemists optimize chemical reaction conditions such as temperature, concentration, ligand, and catalyst. Its suite combines Bayesian optimization algorithms, predictive models trained on proprietary experimental data from high-throughput wet-lab robotics, and automated LCMS spectrum analysis to identify high-yielding reactions in days rather than months.
Product overview
Yoneda Labs offers a suite of AI-powered software products for chemistry optimization. The core portfolio consists of three integrated products: Yoneda Optimize (desktop application for Bayesian optimization of reaction conditions), Yoneda Predict (AI model for predicting high-yielding reaction conditions), and Yoneda Analyze (automated LCMS data analysis). The products work together to help chemists optimize reactions in days instead of months, with the software doubling chemists' efficiency by leveraging machine learning algorithms trained on experimental data.
Differentiator
Problem solved
Functional benefit
Brands
- Yoneda Predict: AI-powered prediction tool for reliable conditions for novel reactions, helping nominate lead compounds faster and double the number of analogs synthesized.
- Yoneda Optimize
- Yoneda Analyze
Products and services
- Yoneda Optimize Desktop software using Bayesian optimization algorithms to help chemists identify optimal reaction conditions (ligand, base, solvent, temperature, concentration) in days instead of months. Includes statistical experiment design, ML-driven model predictions, and visualization of results, targeted at process chemists in pharma and chemical manufacturing.
- Yoneda Predict AI model trained on tens of thousands of wet-lab-generated data points that predicts reliable, high-yielding conditions for novel chemical reactions. Designed for medicinal and process chemists who need to nominate lead compounds faster and synthesize more analogs without iterative trial-and-error experimentation.
- Yoneda Analyze Automated LCMS spectrum analysis tool that detects and integrates even overlapping chromatogram peaks, associates peaks with their masses, and visualizes all LCMS data on a single page, saving approximately 5 minutes of manual labor per chromatogram.
Quantifiable outcome
- 3x faster reaction optimization
- +4 more outcomes
Companies that use YonedaLabs
Customer profileNamed customers1 record
Segments3 records
Ideal customer profiles3 records
YonedaLabs technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability4 records
Feature5 records
YonedaLabs partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- Symerescore partnershipStrategic collaboration with Symeres, a leading transatlantic small molecule contract research and manufacturing organization (CRO/CDMO). The collaboration focused on optimizing transition metal catalyzed cross-coupling reactions using Yoneda Labs' AI-powered software. The partnership successfully improved reaction yields from ~30% to >90%, demonstrating the commercial value of Yoneda's technology. Symeres serves pharmaceutical and biotech clients requiring synthesis services.
Scale indicators6 records
Recent moves5 records
Expansion highlights5 records
YonedaLabs competitors and assessment
Company assessmentMarket position
Competitive moat3 records
Key risks6 records
Key highlights7 records
Customer concentration
YonedaLabs social profiles
Digital presenceYonedaLabs financial estimates
Financial estimateRevenue estimate
Valuation estimate
YonedaLabs leadership team
Management profileNumber of profiles
Profiles4 records
YonedaLabs funding detail
Funding detailFunding overview
Funding rounds1 record
Investors10 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
YonedaLabs M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about YonedaLabs
What does YonedaLabs do?
YonedaLabs builds AI-powered desktop and cloud software that helps chemists optimize chemical reaction conditions such as temperature, concentration, ligand, and catalyst. Its suite combines Bayesian optimization algorithms, predictive models trained on proprietary experimental data from high-throughput wet-lab robotics, and automated LCMS spectrum analysis to identify high-yielding reactions in days rather than months.
Is YonedaLabs a public or private company?
YonedaLabs is a private company. It is classified as venture growth investor backed and is currently operating.
When was YonedaLabs founded?
YonedaLabs was founded in 2023. It employs 1 to 10 people.
Where is YonedaLabs based?
YonedaLabs is headquartered in San Francisco, United States, in the North America region.
How does YonedaLabs make money?
One revenue line is on record: software Licenses.
Does YonedaLabs have an API?
No public API is recorded for YonedaLabs.
What industry is YonedaLabs in?
YonedaLabs's product category is AI Reaction Optimization Software. Its primary akta.pro industry code is HLAGAJAO, AI/ML Platforms for Drug Discovery & Experiment Optimization, with a secondary code of HLAGAFAM, In Silico / Computational Toxicology & PK/PD Modeling. Its NAICS code is 334516 and its SIC code is 7372.