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Promethera Biosciences

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uuid00021nr

Namestring
Promethera Biosciences
Websiteurl
promethera.com
Company typeenum
Private
Founded yearint
2009
Descriptiontext

Promethera Biosciences is a Belgium-based, privately held biopharmaceutical company founded in 2009 and headquartered in Mont-Saint-Guibert that develops cell therapy products for the treatment of liver diseases. The company operates in the advanced therapy medicinal product (ATMP) domain, building biological assets aimed at patients with liver disorders, and has expanded its capabilities through inorganic moves, including the April 2018 acquisition of Baliopharm.

The company has funded its development through a sustained series of equity rounds totaling approximately $149 million between 2010 and 2019, drawing a mix of specialized life-sciences investors (EQT Life Sciences, Vesalius Biocapital Partners, Fund+, S.R.I.W.), Belgian public investors (SFPI-FPIM, Limburgse Reconversie Maatschappij), strategic corporate investors (Boehringer Ingelheim and its Venture Fund, Shire), and Asian institutional and corporate backers (Mitsui Global Investment, Mitsubishi UFJ Capital, Shibuya Kogyo, Shinsei Corporate Investment, Sansei Capital Investment, Sony Innovation Fund, Pegasus Tech Ventures). The leadership team is led by CEO and President John Tchelingerian, with Claude Dedry as Chief Operating Officer, William Macias as Chief Medical Officer ad interim, and Bertrand Lellouche as Group CFO, and the organization employs between 101 and 250 people.

No commercial product, pricing structure, revenue model, partnership economics, customer base, or product pipeline detail is disclosed in the available input data. The company remains private and pre-commercial in the observable record, with strategic activity concentrated in capital raising and selective M&A. The website scrape associated with the firmographic record contained unrelated Vietnamese-language sports news content rather than biotech-specific company information, limiting the granularity of first-party operational data.

Short descriptiontext

Promethera Biosciences is a privately held Belgium-based biopharmaceutical company founded in 2009 that develops cell therapy products to treat liver diseases, having raised approximately $149 million across multiple funding rounds through 2019.

Ownership categoryenum
Headcount rangeband
101–250
akta.pro rankint
HeadquartersMont-saint-guibert, Belgium
HQ citystring
Mont-saint-guibert
HQ countrystring
Belgium
HQ regionstring
Europe
Markets served

Serves global market

Keyword5 values
cell therapy products, liver disease treatments, biopharmaceutical development, regenerative medicine, hepatology therapeutics
Industry3 codes
1Cell Therapy Developers (Allogeneic/Off-the-shelf)
CodeHLAAABABPrimaryYes
2Hepatology & Liver Disease
CodeHLAKAEABPrimaryNo
3Gastroenterology & Hepatology Pharmaceuticals
CodeHLAIAAAIPrimaryNo
NAICS code2 codes
  • Biological Product (except Diagnostic) Manufacturing325414
  • Pharmaceutical Preparation Manufacturing325412
SIC code2 codes
  • Biological Products, (No Disgnostic Substances)2836
  • Pharmaceutical Preparations2834
Product category
Cell Therapy Biopharmaceuticals
Cost components5 values
Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

Promethera Biosciences develops and manufactures cell therapy products aimed at treating liver diseases. The company operates as a biopharmaceutical firm focused on biological therapeutics for hepatic conditions, including advanced therapies derived from cell-based platforms. Its work centers on translating cell therapy science into treatments for patients with serious liver disorders.

Differentiator
Functional benefit
Problem solved
Product overview1 text field

Promethera.com is a unified sports news portal that aggregates and publishes Vietnamese-language content across three sports verticals: football (bóng đá), baseball (bóng chày), and table tennis (bóng bàn). The platform publishes educational articles about sports rules, techniques, equipment, player profiles, stadium histories, and transfer news.

Product and service1 record
1Cell therapy products for liver diseases
Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight4 records

Each record includes

Type, Description

Peers10 records
1Promethera Biosciences (HepaStem asset)
TypeDirect peer
Description

Note: Promethera Biosciences is the subject company; this row is intentionally not used as a peer.

TypeDirect peer
Description

Clinical-stage cell therapy company developing allogeneic liver cell therapies delivered via lymph node injection to regenerate liver function. Directly comparable to Promethera's HepaStem approach in liver disease indications.

TypeEmerging player
Description

UK-based clinical-stage biotech developing RNA-based therapeutics for liver disease and cancer. Comparable as a liver-focused biotech with platform technology targeting similar indications, though using RNA activation rather than cell therapy.

TypeDirect peer
Description

Clinical-stage allogeneic CAR T cell therapy developer. Comparable as an allogeneic cell therapy platform company with similar manufacturing, regulatory, and development challenges, though focused on oncology rather than liver disease.

TypeDirect peer
Description

Allogeneic T-cell therapy developer with off-the-shelf platform. Comparable business model as an allogeneic cell therapy company with similar manufacturing approach and clinical development timelines.

TypeBroad incumbent
Description

Established cell and blood processing technology provider. Comparable as an infrastructure player in the cell therapy ecosystem, though serving the broader cell therapy industry rather than competing in liver disease specifically.

TypeBroad incumbent
Description

Major biopharmaceutical company with significant cell therapy programs (via ViaCyte acquisition for diabetes) and broader hepatology franchise through CF treatments. Comparable as a well-capitalized player moving into cell therapy.

TypeBroad incumbent
Description

Global pharmaceutical company and Promethera investor (via Shire acquisition). Has significant hepatology and rare disease franchises and could serve as an exit/partner for Promethera's liver programs.

TypeBroad incumbent
Description

Major pharmaceutical company with significant hepatology franchise (e.g., Pegasys, hepatitis treatments). Relevant as a potential commercial partner or acquirer for liver disease therapies.

TypeEmerging player
Description

Earlier-stage cell therapy company developing regenerative therapies. Comparable as a smaller cell therapy peer in the regenerative medicine space.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat4 records

Each record includes

Type, Details

Key risks4 records

Each record includes

Headline, Details, Source

Key highlights5 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Ideal customer profile1 record

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles4 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds7 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors18 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Promethera Biosciences

Cell Therapy Biopharmaceuticalspromethera.com

Promethera Biosciences is a privately held Belgium-based biopharmaceutical company founded in 2009 that develops cell therapy products to treat liver diseases, having raised approximately $149 million across multiple funding rounds through 2019.

What Promethera Biosciences does

Promethera Biosciences is a Belgium-based, privately held biopharmaceutical company founded in 2009 and headquartered in Mont-Saint-Guibert that develops cell therapy products for the treatment of liver diseases. The company operates in the advanced therapy medicinal product (ATMP) domain, building biological assets aimed at patients with liver disorders, and has expanded its capabilities through inorganic moves, including the April 2018 acquisition of Baliopharm.

The company has funded its development through a sustained series of equity rounds totaling approximately $149 million between 2010 and 2019, drawing a mix of specialized life-sciences investors (EQT Life Sciences, Vesalius Biocapital Partners, Fund+, S.R.I.W.), Belgian public investors (SFPI-FPIM, Limburgse Reconversie Maatschappij), strategic corporate investors (Boehringer Ingelheim and its Venture Fund, Shire), and Asian institutional and corporate backers (Mitsui Global Investment, Mitsubishi UFJ Capital, Shibuya Kogyo, Shinsei Corporate Investment, Sansei Capital Investment, Sony Innovation Fund, Pegasus Tech Ventures). The leadership team is led by CEO and President John Tchelingerian, with Claude Dedry as Chief Operating Officer, William Macias as Chief Medical Officer ad interim, and Bertrand Lellouche as Group CFO, and the organization employs between 101 and 250 people.

No commercial product, pricing structure, revenue model, partnership economics, customer base, or product pipeline detail is disclosed in the available input data. The company remains private and pre-commercial in the observable record, with strategic activity concentrated in capital raising and selective M&A. The website scrape associated with the firmographic record contained unrelated Vietnamese-language sports news content rather than biotech-specific company information, limiting the granularity of first-party operational data.

Promethera Biosciences firmographics

Firmographics
Name
Promethera Biosciences
Website
https://promethera.com
Company type
Private
Founded year
2009
Headcount range
101–250 employees
Short description
Promethera Biosciences is a privately held Belgium-based biopharmaceutical company founded in 2009 that develops cell therapy products to treat liver diseases, having raised approximately $149 million across multiple funding rounds through 2019.
Ownership category
akta.pro rank

Promethera Biosciences industry classification

Industry
Product category
Cell Therapy Biopharmaceuticals
NAICS
Biological Product (except Diagnostic) Manufacturing (325414), Pharmaceutical Preparation Manufacturing (325412)
SIC
Biological Products, (No Disgnostic Substances) (2836), Pharmaceutical Preparations (2834)
akta.pro primary industry
Cell Therapy Developers (Allogeneic/Off-the-shelf) (HLAAABAB)
akta.pro secondary industries
Hepatology & Liver Disease (HLAKAEAB), Gastroenterology & Hepatology Pharmaceuticals (HLAIAAAI)

Keywords

  • Cell therapy products
  • Liver disease treatments
  • Biopharmaceutical development
  • Regenerative medicine
  • Hepatology therapeutics

Where Promethera Biosciences is headquartered

Location

Headquarters

HQ city
Mont-saint-guibert
HQ country
Belgium
HQ region
Europe

Markets served

Promethera Biosciences business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Technology or R&D, Personnel, Operations, Marketing or Sales, Infrastructure

Promethera Biosciences product offering

Product offering

Core offering

Promethera Biosciences develops and manufactures cell therapy products aimed at treating liver diseases. The company operates as a biopharmaceutical firm focused on biological therapeutics for hepatic conditions, including advanced therapies derived from cell-based platforms. Its work centers on translating cell therapy science into treatments for patients with serious liver disorders.

Product overview

Promethera.com is a unified sports news portal that aggregates and publishes Vietnamese-language content across three sports verticals: football (bóng đá), baseball (bóng chày), and table tennis (bóng bàn). The platform publishes educational articles about sports rules, techniques, equipment, player profiles, stadium histories, and transfer news.

Differentiator

Problem solved

Functional benefit

Products and services

  • Cell therapy products for liver diseases

Companies that use Promethera Biosciences

Customer profile

Ideal customer profiles1 record

Promethera Biosciences technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Promethera Biosciences partnerships and signals

Strategic signal

Recent moves6 records

Expansion highlights4 records

Promethera Biosciences competitors and assessment

Company assessment

Direct peers

  • Promethera Biosciences (HepaStem asset): Note: Promethera Biosciences is the subject company; this row is intentionally not used as a peer.
  • Lygenesis: Clinical-stage cell therapy company developing allogeneic liver cell therapies delivered via lymph node injection to regenerate liver function. Directly comparable to Promethera's HepaStem approach in liver disease indications.
  • Allogene Therapeutics: Clinical-stage allogeneic CAR T cell therapy developer. Comparable as an allogeneic cell therapy platform company with similar manufacturing, regulatory, and development challenges, though focused on oncology rather than liver disease.
  • Atara Biotherapeutics: Allogeneic T-cell therapy developer with off-the-shelf platform. Comparable business model as an allogeneic cell therapy company with similar manufacturing approach and clinical development timelines.

Emerging players

  • MiNA Therapeutics: UK-based clinical-stage biotech developing RNA-based therapeutics for liver disease and cancer. Comparable as a liver-focused biotech with platform technology targeting similar indications, though using RNA activation rather than cell therapy.
  • Humacyl Pharma: Earlier-stage cell therapy company developing regenerative therapies. Comparable as a smaller cell therapy peer in the regenerative medicine space.

Broad incumbents

  • Terumo BCT: Established cell and blood processing technology provider. Comparable as an infrastructure player in the cell therapy ecosystem, though serving the broader cell therapy industry rather than competing in liver disease specifically.
  • Vertex Pharmaceuticals: Major biopharmaceutical company with significant cell therapy programs (via ViaCyte acquisition for diabetes) and broader hepatology franchise through CF treatments. Comparable as a well-capitalized player moving into cell therapy.
  • Takeda Pharmaceutical (Shire): Global pharmaceutical company and Promethera investor (via Shire acquisition). Has significant hepatology and rare disease franchises and could serve as an exit/partner for Promethera's liver programs.
  • Roche: Major pharmaceutical company with significant hepatology franchise (e.g., Pegasys, hepatitis treatments). Relevant as a potential commercial partner or acquirer for liver disease therapies.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks4 records

Key highlights5 records

Customer concentration

Promethera Biosciences social profiles

Digital presence

Promethera Biosciences financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Promethera Biosciences leadership team

Management profile

Number of profiles

Profiles4 records

Promethera Biosciences funding detail

Funding detail

Funding overview

Funding rounds7 records

Investors18 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Promethera Biosciences M&A and investment

M&A and investment

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Promethera Biosciences

What does Promethera Biosciences do?

Promethera Biosciences develops and manufactures cell therapy products aimed at treating liver diseases. The company operates as a biopharmaceutical firm focused on biological therapeutics for hepatic conditions, including advanced therapies derived from cell-based platforms. Its work centers on translating cell therapy science into treatments for patients with serious liver disorders.

When was Promethera Biosciences founded?

Promethera Biosciences was founded in 2009. It employs 101 to 250 people.

Where is Promethera Biosciences based?

Promethera Biosciences is headquartered in Mont-saint-guibert, Belgium, in the Europe region.

Who are Promethera Biosciences's main competitors?

Direct peers on record are Promethera Biosciences (HepaStem asset), Lygenesis, Allogene Therapeutics and Atara Biotherapeutics. Emerging players are MiNA Therapeutics and Humacyl Pharma. Broad incumbents are Terumo BCT, Vertex Pharmaceuticals, Takeda Pharmaceutical (Shire) and Roche.

Does Promethera Biosciences have an API?

No public API is recorded for Promethera Biosciences.

What industry is Promethera Biosciences in?

Promethera Biosciences's product category is Cell Therapy Biopharmaceuticals. Its primary akta.pro industry code is HLAAABAB, Cell Therapy Developers (Allogeneic/Off-the-shelf), with a secondary code of HLAKAEAB, Hepatology & Liver Disease. Its NAICS code is 325414 and its SIC code is 2836.

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Live signals
FinSMEsPromethera Receives €7.5M Investment; Closes €47.2M Series DPromethera Biosciences added €7.5M to its €39.7M Series D, led by Sony Innovation Fund and Pegasus Tech Ventures. The company will use proceeds to advance NASH and ACLF clinical programs and initiate trials outside Europe in 2020.FinSMEsPromethera Biosciences Completes $44.4M Series D FinancingPromethera Biosciences closed a €39.7M Series D financing co-led by ITOCHU and Shinsei Capital Partners. The funds will accelerate its HepaStem clinical program in ACLF, launch its first NASH trial, and scale manufacturing and operations.FinSMEsPromethera Biosciences Raises €10M in Series C FundingPromethera Biosciences raised €10M in Series C financing from existing and new investors. The funds will expand product development to larger liver disease indications such as ACLF, NASH, and fibrosis, accelerating these toward the clinic.PR NewswireBioLife Solutions' CryoStor® Embedded in Manufacturing Process for Promethera Biosciences HepaStem Cell-Based Treatment for Liver DisordersBioLife Solutions announced that its clinical grade CryoStor freeze media has been embedded into the manufacturing process for Promethera Biosciences' HepaStem cell-based treatment targeting metabolic liver disorders including hemophilia, acute/chronic liver failure, fibrosis, and NASH. The adoption enables at least two years of frozen storage and global distribution of the cellular therapy, with Promethera's VP of Operations citing validated high cell recovery and viability following the manufacturing process. CryoStor and HypoThermosol are now incorporated into more than 220 customer pre-clinical validations and clinical trials across multiple therapeutic areas.FinSMEsPromethera Biosciences Buys CytonetPromethera Biosciences acquired Cytonet GmbH & Co KG, a cellular therapy company, in exchange for Promethera shares. The Hopp family will hold up to 13% of the share capital after the deal. Promethera will add a U.S. facility in Durham, NC, and a German team to support a new drug submission for Heparesc.FinSMEsPromethera Biosciences Completes €25.33M Series C Funding RoundPromethera Biosciences completed a €25.33M Series C round led by Vesalius Biocapital and Boehringer Ingelheim Venture Fund, with participation from SRIW, Shire, and others. The company will use the funds for clinical development of HepaStem and a collaboration with EMD-Millipore. The Walloon region also provided €5M in loans and subsidies.FinSMEsBelgium, Promethera® Biosciences Raises €5.3M Series A FinancingPromethera Biosciences, a Belgian stem cell therapy company, closed a €5.3M Series A round led by Vesalius Biocapital. The funds will complete pre-clinical studies for its Promethera HepaStem liver therapy and HepaScreen cell model. The round will be completed with significant public funding.