Allevi

What Allevi does

Allevi (formerly BioBots) is a Philadelphia-based 3D bioprinting company founded in 2014 and now operating as a subsidiary of 3D Systems (NYSE: DDD). The company built an integrated ecosystem of desktop bioprinters, tissue-specific bioinks, precision accessories, and workflow software targeted at academic, pharmaceutical, and biotech researchers conducting tissue engineering, organ-on-a-chip, drug discovery, and regenerative medicine work. Core technology centers on extrusion-based bioprinting with patented CORE (Cell Optimized Removable Extruders) printheads that integrate UV and Blue LED photocuring with homogeneous cooling/heating, enabling high cell viability across diverse bioink formulations from hard (bone) to soft (brain) tissues using a single printhead architecture. Supporting features include auto-calibration, precision linear rails enabling single-micron movements on X/Y/Z axes, multi-material capability (up to three extruders on Allevi 3 with coaxial and triaxial nozzles), and sterility-optimized hardware designed for cell-culture hood workflows.

Allevi monetized through hardware sales of its three bioprinter models (Allevi 1, 2, and 3), recurring revenue from bioinks and consumables (Lifeink, PhotoHA, PhotoCol, PureCol, GelMA, Sodium Alginate, Hyperelastic Bone, PCL), software licensing (Bioprint Online, Bioprint Pro), and customized bioprinting services. Distribution combined direct e-commerce with a five-country authorized distributor network spanning China, Hong Kong, India, Japan, and Brazil, alongside enterprise field sales for pharmaceutical and biotech accounts. Devices were sold into 40+ countries with a customer base spanning hundreds of research labs globally, including collaborations with the Wistar Institute (COVID-19 lung models) and academic groups at NJIT, the University of Sheffield, and others in France.

The company's strategic position has shifted materially following its acquisition by 3D Systems. In August 2020, the leadership team was restructured with veteran healthcare executive Frank J. McCaney as CEO, co-founder Ricky Solorzano moving to CTO, and Taciana Pereira elevated to CSO. Effective July 27, 2023, 3D Systems discontinued production of Allevi bioprinters and scheduled end-of-service-life for July 27, 2026; Allevi now operates primarily as a materials and consumables supplier for the installed base through its e-commerce storefront.

Name

Allevi

Legal name

Allevi, Inc.

Website

https://allevi3d.com

Company type

Private

Founded year

2014

Operating status

Acquired

Headcount range

11–50 employees

Short description

Allevi is a Philadelphia-based 3D bioprinting company, now a 3D Systems subsidiary, that sells desktop bioprinters, bioinks, accessories, and workflow software to academic, pharmaceutical, and biotech researchers for tissue engineering and drug discovery applications.

Ownership category

akta.pro rank

Product category

3D Bioprinting Equipment and Bioinks

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Plastics and Rubber Products Manufacturing (326)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Biological Products, (No Disgnostic Substances) (2836)

akta.pro primary industry

3D Bioprinting & Biofabrication (HLAAAGAC)

akta.pro secondary industries

Bioprinting & Biofabrication Systems (Tissue/Cell Printing Hardware) (IMAAAAAG), Recycled & Sustainable 3D Printing Materials (Bio-based/Regrind) (IMAAABAK)

Keywords

• 3D bioprinters
• Bioink materials
• Tissue engineering
• Bioprinting software
• Organ-on-chip research

Headquarters

HQ city

Philadelphia

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Bioinks and Materials: Recurring revenue from sale of bioinks including collagen, GelMA, hyaluronic acid derivatives, alginate, and specialty materials. Also includes consumables like syringes, nozzles, photoinitiators, and crosslinking agents.
2. Bioprinting Software: Advanced software for bioprinting workflow automation including Allevi Bioprint Online and Bioprint Pro. Software licensing and subscription revenue.
3. Bioprinting Services: Custom bioprinting services and customized solutions for researchers needing assistance with specific applications or tissue models.
4. Accessories and Parts: Replacement parts, accessories, and peripheral equipment for bioprinters including power supplies, extruder components, and maintenance items.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Allevi offers desktop 3D bioprinters along with a comprehensive ecosystem of bioinks, reagents, accessories, and software that enable researchers to design and engineer 3D tissue models. The patented CORE printhead technology supports extrusion-based bioprinting with photocuring across diverse biomaterials and cell lines. While bioprinter production was discontinued effective July 27, 2023 by parent company 3D Systems, the company continues to sell bioinks and materials via e-commerce and supports installed devices through July 27, 2026.

Product overview

Allevi (formerly BioBots) is a 3D bioprinting company that offers an integrated ecosystem of hardware, materials, and software for bioprinting applications. The product portfolio centers on three desktop bioprinter models—Allevi 1 (entry-level), Allevi 2 (mid-range), and Allevi 3 (advanced with triple extruder and patented CORE printheads)—alongside a comprehensive range of bioinks including collagen-based products (Lifeink®, PureCol®), photocurable materials (PhotoHA®, PhotoCol®, GelMA), and polymers (Sodium Alginate, PCL, Hyperelastic Bone™). The ecosystem is complemented by precision accessories (coaxial and triaxial nozzles, metal and plastic syringes and tips), reagents (LAP photoinitiator, Calcium Chloride), and molding materials (PDMS, Silicone Mold), supported by dedicated bioprinting software and services. As of July 2023, the company discontinued bioprinter production while continuing to sell materials and support existing customers through July 2026.

Differentiator

Problem solved

Functional benefit

Products and services

• Allevi 1 Bioprinter Entry-level desktop 3D bioprinter with the smallest footprint, widest material capabilities, and most affordable price point in the Allevi lineup. Features auto-calibration and is compatible with 5 mL syringes for extrusion-based bioprinting of tissues and disease models. Production was discontinued by 3D Systems effective July 27, 2023 with end of service life scheduled for July 27, 2026.
• Allevi 2 Bioprinter Mid-range desktop 3D bioprinter sold globally, compatible with 10 mL syringes and featuring extrusion-based bioprinting technology for tissue engineering and drug discovery applications. Production discontinued by 3D Systems effective July 27, 2023 with end of service life scheduled for July 27, 2026.
• Allevi 3 Bioprinter Advanced desktop 3D bioprinter with triple extruder capability and patented CORE (Cell Optimized Removable Extruders) printheads featuring UV and Blue LED photocuring. Includes auto-calibration, precision linear rails for single-micron movements on X/Y/Z axes, and sterility-optimized design for use under cell-culture hoods. Described as 'The Bioprinter for Every Application'. Production discontinued by 3D Systems effective July 27, 2023 with end of service life scheduled for July 27, 2026.
• Lifeink 200 Bioink Collagen-based bioink for bioprinting liver, heart, bone, cartilage, kidney, nervous system, skin, vascularization, lung, and brain tissues. Available for purchase via the Allevi online shop.
• Lifeink 240 Bioink Collagen-based bioink offered alongside Lifeink 200 in Allevi's portfolio for tissue-specific 3D bioprinting applications.
• PhotoHA Bioink Methacrylated hyaluronic acid bioink for photocurable 3D bioprinting applications.
• PhotoCol Bioink Methacrylated collagen bioink for photocurable 3D bioprinting applications.
• PureCol Bioink Type 1 Bovine Collagen bioink for tissue engineering applications.
• GelMA Bioink Photocrosslinkable gelatin methacrylate hydrogel matrix widely used for extrusion-based bioprinting, available in lyophilized powder form.
• Sterile GelMa Solution Ready-to-use sterile gelatin methacrylate (GelMa) solution for bioprinting applications requiring sterile hydrogels.
• Sodium Alginate Bioink Alginate-based bioink used with calcium chloride for ionic crosslinking, sold in packs of 3 units.
• Hyperelastic Bone Bioink 3D graphene-based bioink (Hyperelastic Bone) for printing bone tissue constructs in hard-tissue bioprinting applications.
• Polycaprolactone (PCL) Bioink Thermoplastic polymer (PCL) bioink for hard tissue bioprinting applications requiring high melt temperatures.
• PLGA Bioink Poly(lactic-co-glycolic acid) (PLGA) bioink offered for bioprinting applications.
• Human Collagen Type III Human Collagen Type III additive for tissue-specific bioprinting applications.
• Pluronic Bioink Pluronic bioink for 3D bioprinting applications, often used as a sacrificial material.
• Gelatin Bioink Gelatin bioink for tissue engineering applications.
• LAP Photoinitiator Photoinitiator for photocrosslinking bioinks in light-based bioprinting workflows, available in various pack sizes.
• Calcium Chloride (pack of 3) Calcium chloride salt for preparing crosslinking baths used with sodium alginate and similar ionically crosslinkable bioinks, sold in 3 x 50g vials.
• PDMS (Polydimethylsiloxane) Flexible, high-definition clear polydimethylsiloxane (PDMS) molding and encapsulation material for microfluidics and prototyping, with cured tensile strength 5.5-7.0 MPa, elongation 80-100%, and Shore A 45-60.
• Coaxial Nozzle Nozzle kit that allows users to mix bioinks from two syringes during bioprinting for materials requiring curing catalysts or liquid crosslinking agents, available in gauges 20, 22, and 28.
• Triaxial Nozzle Kit Nozzle kit compatible with the Allevi 3 bioprinter that allows mixing of bioinks from three syringes during printing, with 22g inner, 18g middle, and 14g outer needle gauge sizes.
• Full Metal Nozzles Reusable, autoclaveable stainless steel nozzles with inside diameters ranging from 100 µm to 600 µm and a tapered design that minimizes internal steps and maximizes flow rates.
• Metal Syringes (5 mL and 10 mL) Stainless steel luer lock syringes (5 mL and 10 mL) designed for printing materials requiring high melt temperatures, compatible with specific Allevi bioprinter models.
• Plastic Syringes (5 mL and 10 mL) Polypropylene syringes with luer lock connector, available in 5 mL and 10 mL sizes and in standard, sterile, and amber-tinted variants.
• Metal Tips Standard bore tapered metal tips for high-accuracy dispensing with Luer Lock thread, available in gauges 19G through 30G.
• Plastic Tips Polypropylene plastic double-helix hub tips with UV-bonded stainless steel cannula, available in gauges 23G-30G in various lengths.
• Silicone Mold Flexible silicone molds useful for making microfluidic chips and organs-on-chips; easily detach from PDMS post-curing, sold in packs of 2 with 2.5 x 2.5 x 1 inch dimensions.
• Replacement O-rings Rubber O-rings for Allevi print head twist-cap maintenance, available in CORE Print Head (White) and High Temp Print Head (Black) variants, sold in packs of 2.
• Allevi Bioprinting Software Advanced software platform for bioprinting workflow automation, including Allevi Bioprint Online, Bioprint Pro, and slicer tools for print parameter optimization. Generates software licensing and subscription revenue.
• Allevi Bioprinting Services Custom bioprinting services and full-service support including customized solutions for researchers needing assistance with specific applications or tissue models, enabling integration of bioprinting into research protocols.

Quantifiable outcome

• Reduces experiment time from a month to 3-4 days with integrated software and materials workflow
• +1 more outcomes

Named customers4 records

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Eight partnerships are on record, tiered core and minor.

• Wistar InstitutecoreStrategic or Co-development Partner · 25 June 2020Collaboration to use 3D bioprinting to combat COVID-19. Allevi applied its patented 3D bioprinting platform to create three-dimensional lung models that Wistar scientists used to study SARS-CoV-2 infection mechanisms. Project led by David B. Weiner, Ph.D. with Allevi VP Taciana Pereira as co-principal investigator.
• Volumetric Inc.coreTechnology or IntegrationPartner for Carbohydrate Glass sacrificial material used in organ-on-a-chip bioprinting protocols. Carbohydrate Glass enables creation of high-resolution microchannels within PDMS devices. Material featured in Nature Materials publication by Jordan Miller.
• Cy-Tech Biotech Co.minorChannel Partner/ Reseller/ DistributorAuthorized distributor for Allevi products in China. Located at 768 DCP, 5th Xueyuan Road, Haidian District, Beijing, China. Provides pre-sale and post-sale support for Chinese market.
• Griffin BiotechminorChannel Partner/ Reseller/ DistributorAuthorized distributor for Allevi products in Hong Kong. Located at 928-930 Cheung Sha Wan Road, Suite 703, Lai Chi Kok, Kowloon, Hong Kong.
• Biotron HealthcareminorChannel Partner/ Reseller/ DistributorAuthorized distributor for Allevi products in India. Located at 301, Coral Classic, 20th Road, Chembur, Mumbai - 400 71 India. Toll-free support line available.
• FilgenminorChannel Partner/ Reseller/ DistributorAuthorized distributor for Allevi products in Japan. Located at 1-1409 Jonoyama, Midori-ku, Nagoya, 459-8011 Japan.
• UniscienceminorChannel Partner/ Reseller/ DistributorAuthorized distributor for Allevi products in Brazil. Located at Av. Dos Remédios, 1.077, CEP 06298-006 - Osasco, Sao Paulo, Brazil.
• Robert Langer (MIT)coreStrategic or Co-development PartnerScientific Advisory Board member, David H. Koch Institute Professor at MIT. Provided commentary on Allevi-Wistar COVID-19 collaboration, noting potential as significant asset in fight against COVID-19.

Scale indicators4 records

Recent moves7 records

Expansion highlights4 records

Broad incumbents

• Formlabs: Desktop SLA 3D printing incumbent serving dental, medical, and engineering markets with a strong hardware plus materials ecosystem. While focused on non-biological applications, its desktop form factor and material-driven business model closely mirror Allevi's go-to-market approach, particularly in healthcare verticals.
• 3D Systems: Allevi's parent company and a publicly-traded broad incumbent in industrial 3D printing (NYSE: DDD). Operates a wide portfolio across polymer, metal, and bioprinting technologies; acquired Allevi as part of its healthcare/bioprinting expansion but has since discontinued Allevi hardware. Provides strategic context for Allevi's positioning within a much larger portfolio.
• Stratasys: Leading industrial polymer 3D printing incumbent (NASDAQ: SSYS) with broad product portfolio across FDM, PolyJet, and SAF technologies. While not focused on bioprinting, competes broadly in the desktop and professional 3D printing markets where Allevi's bioprinters sit adjacent. Includes bioprinting-adjacent offerings through partners.

Direct peers

• Poietis: French bioprinting company using laser-assisted bioprinting technology for tissue engineering and pharmaceutical applications. Direct peer in life sciences bioprinting, targeting similar pharmaceutical and cosmetic industry customers for in vitro tissue models.
• regenHU: Swiss manufacturer of multi-head bioprinters for tissue engineering and regenerative medicine, with biomaterial and bioink offerings. Direct competitor in extrusion-based bioprinter hardware, serving academic and pharma research labs with comparable product positioning to Allevi.
• Aspect Biosystems: Canada-based bioprinting company developing microfluidic 3D bioprinting technology for tissue engineering and therapeutic applications. Direct competitor in the bioprinter hardware and bioink markets, with strategic partnerships with pharma companies (e.g., Roche, Bayer) that mirror Allevi's enterprise pharma ambitions.
• CELLINK (BICO): Direct competitor offering a comprehensive bioprinting ecosystem including extrusion-based bioprinters, bioinks, and lab automation. BICO has aggressively consolidated the bioprinting market through acquisitions (including MatTek, Visikol, Allegro 3D) and competes head-on with Allevi across hardware and consumables, particularly in pharma and academic research labs.
• Organovo: Pioneer in 3D bioprinted human tissue with a focus on therapeutic applications, particularly liver tissue for drug discovery and inflammatory bowel disease. Competes with Allevi in the pharma preclinical tissue model market and serves similar pharmaceutical and academic customers seeking 3D tissue models for research.

Emerging players

• Emulate Inc. Organ-on-chip platform company providing Liver-Chip, Lung-Chip, and other microfluidic tissue models for drug discovery. Adjacent competitor in the human-relevant in vitro testing market that overlaps with Allevi's pharmaceutical drug discovery value proposition, though focused on organ-on-chip rather than 3D bioprinting.

Others

• Volumetric Inc. Carbohydrate Glass sacrificial material supplier partnered with Allevi for organ-on-chip bioprinting protocols (Nature Materials publication with Jordan Miller). An enabling technology partner rather than direct competitor; provides the sacrificial material infrastructure that powers Allevi's organ-on-chip workflows.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/channel/UCVdo_7ZDwcvD9QxeiOQFYPg
• LinkedInlinkedin.com/company/allevi

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds11 records

Investors19 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Allevi