City of Hope
City of Hope is a nonprofit NCI-Designated Comprehensive Cancer Center operating 39 clinical sites across four states, delivering integrated cancer research, treatment, and graduate education to over 150,000 new patients annually with a national clinical trials platform serving biotech and pharma sponsors.
- Company typePrivate
- Founded1913
- HeadquartersDuarte, United States
- Headcount5,001–10,000
- GTM typeB2C
- OfferingServices
What City of Hope does
City of Hope is one of the largest cancer research and treatment organizations in the United States, founded in 1913 and headquartered in Duarte, California. Designated as an NCI Comprehensive Cancer Center, it operates a national network of 39 clinical sites across California, Arizona, Illinois, and Georgia, anchored by five major cancer centers in Los Angeles, Orange County, Phoenix, Chicago, and Atlanta, serving approximately 86 million people within a 90-minute radius and more than 150,000 new patients annually. The organization integrates translational research, clinical treatment, and graduate education under one enterprise, with over 700 physicians, nearly 2,000 researchers, and wholly-owned subsidiaries including the Beckman Research Institute, TGen, the Arthur Riggs Diabetes & Metabolism Research Institute, and the Irell & Manella Graduate School of Biological Sciences.
City of Hope's core technology platform spans clinical care delivery, a national cloud-based clinical trials matching system (Hope Pathways) spanning 39 sites, and a portfolio of proprietary diagnostic and AI tools including JAYseq clinical whole-genome sequencing (72-hour turnaround for multiple myeloma), HopeLLM (an Azure-based NLP documentation tool deployed for 150,000+ annual new patients), the MechanoAge ML breast cancer risk platform, and InflaMix for CAR-T outcome prediction. Its research infrastructure includes over 800 active clinical studies and more than 20,000 bone marrow transplants performed since 1976.
City of Hope generates revenue through a diversified nonprofit model: direct patient care and treatment services billed to insurance (PPO, HMO, Medicare, MediCal, Covered California), sponsored clinical trial agreements with biotechnology and pharmaceutical companies, research grants (including from CIRM), philanthropy via the Spirit of Life gala tradition and Walk for Hope community fundraising, and an expanding intellectual property commercialization function led by a dedicated Chief Commercialization Officer. The organization goes to market through physician referral networks, a national clinical trials platform serving as a partnership model for biotech and pharma sponsors, and a multi-state hospital and outpatient clinic network.
City of Hope firmographics
Firmographics- Name
- City of Hope
- Legal name
- City of Hope
- Website
- https://cityofhope.org
- Company type
- Private
- Founded year
- 1913
- Operating status
- Operating
- Headcount range
- 5,001–10,000 employees
- Short description
- City of Hope is a nonprofit NCI-Designated Comprehensive Cancer Center operating 39 clinical sites across four states, delivering integrated cancer research, treatment, and graduate education to over 150,000 new patients annually with a national clinical trials platform serving biotech and pharma sponsors.
- Ownership category
- akta.pro rank
City of Hope industry classification
Industry- Product category
- Oncology Healthcare Services
- NAICS
- Specialty (except Psychiatric and Substance Abuse) Hospitals (622310)
- SIC
- Services-Hospitals (8060), Services-Offices & Clinics Of Doctors Of Medicine (8011), Services-Specialty Outpatient Facilities, Nec (8093)
- akta.pro primary industry
- Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS) (BPAGACAA)
- akta.pro secondary industries
- Hospital-Integrated Cancer Centers (Acute Oncology Programs) (HLAFAAAM), Rare Oncology & Hematologic Malignancy Therapies (HLAIAIAC)
Keywords
Where City of Hope is headquartered
LocationHeadquarters
- HQ city
- Duarte
- HQ country
- United States
- HQ region
- North America
Offices17 records
Markets served
City of Hope business model
Business model- GTM type
- B2C
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Supply Chain, Others
Revenue model
- Patient Care and Treatment Services: City of Hope generates revenue through direct patient care services including chemotherapy, radiation oncology, surgical procedures, cellular therapies, and diagnostic services billed to patients and insurance providers. The organization accepts a wide range of insurance including PPO, HMO, Medicare, MediCal, and Covered California plans.
- Clinical Research and Trials: City of Hope conducts approximately 800 active clinical studies and received record enrollment of approximately 1,400 patients in interventional treatment studies in fiscal year 2025, generating revenue through sponsored research agreements with pharmaceutical and biotechnology companies.
- Biotechnology and Pharmaceutical Partnerships: City of Hope enters into research collaborations, licensing agreements, and clinical trial partnerships with biotech and pharma companies, including the evaluation of commercial diagnostics (e.g., Quest Diagnostics' Haystack MRD) and co-development of novel therapies.
- Philanthropy and Donations: City of Hope raises funds through events including the Spirit of Life Gala (raising over $180 million from the Music, Film and Entertainment Industry Group since 1973), Walk for Hope ($3.3 million across five events), and direct philanthropy. The NLIC Spirit of Life campaign raised more than $1.5 million for prostate cancer and diabetes research.
- Intellectual Property Commercialization: City of Hope appointed a Chief Commercialization Officer to advance the commercialization of its intellectual property, research results, and scientific discoveries, diversifying revenue sources through licensing and spin-out opportunities.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | Standard Patient Care - Insurance-Based Pricing |
| Other | Multi-year contract | Self-Pay and Uninsured Patients |
Go-to-market motion2 records
Distribution channels5 records
Marketing channels7 records
City of Hope product offering
Product offeringCore offering
City of Hope is a nonprofit cancer research and treatment organization that delivers comprehensive cancer care—including surgery, chemotherapy, radiation oncology, immunotherapy, cellular therapy, and targeted therapy—through a national network of hospitals and outpatient clinics across California, Arizona, Illinois, and Georgia. The organization also conducts approximately 800 active clinical studies through its national clinical trials platform and operates a bone marrow transplant program that has performed over 20,000 procedures since 1976, supported by affiliated research institutes such as Beckman Research Institute and TGen.
Product overview
City of Hope is a comprehensive cancer research and treatment organization operating as a single unified national system. Its core offering is patient care across a network of cancer centers in Los Angeles, Orange County, Chicago, Atlanta, and Phoenix. The organization integrates clinical research with treatment delivery through its national clinical trials platform (Hope Pathways) spanning 39 sites, augmented by AI-powered documentation tools (HopeLLM) and specialized diagnostic platforms. Key specialized offerings include bone marrow transplant services (over 20,000 performed since 1976, celebrating 50-year milestone in 2026), CAR T-cell therapy, and regenerative medicine programs supported by CIRM-funded stem cell research laboratories. The organization also develops proprietary diagnostic tests including JAYseq whole-genome sequencing for multiple myeloma and the experimental MechanoAge breast cancer risk assessment platform.
Differentiator
Problem solved
Functional benefit
Brands
- Beckman Research Institute: Core research institute at City of Hope focusing on biomedical research
- TGen (Translational Genomics Research Institute)
- Irell & Manella Graduate School of Biological Sciences
- Hope Pathways
- HopeLLM
- Hope Virtual TeleHealth
- MyCityofHope
- AccessHope
- Arthur Riggs Diabetes & Metabolism Research Institute
- Hematologic Malignancies Research Institute
Products and services
- Comprehensive Cancer Treatment Services Comprehensive cancer care services for patients diagnosed with cancer across all major types and stages, including surgery, chemotherapy, radiation oncology, immunotherapy, cellular therapy, and targeted therapy. Delivered through a national network of 40+ hospital and outpatient locations across California, Arizona, Illinois, and Georgia.
- Bone Marrow Transplant Program FACT-accredited bone marrow transplant (BMT) program for leukemia, lymphoma, myeloma, and other hematologic malignancies. Over 20,000 BMT procedures performed since 1976 with nearly 800 annually, including CAR-T cell therapy and stem cell transplantation services.
- National Clinical Trials Program A national oncology-focused clinical trials platform enabling Phase I-IV studies across 39 sites serving approximately 86 million people within 90 minutes of a clinical site. Achieves first-patient consent in as few as 11 days and enrolled approximately 1,400 patients to interventional treatment studies in FY2025. Available to biotech and pharma sponsors, investigators, and patient participants.
- JAYseq Clinical Whole-Genome Sequencing Test Clinical whole-genome sequencing test for multiple myeloma patients that analyzes all 3 billion base pairs of patient DNA to identify genetic mutations, translocations, and other changes for personalized treatment strategies, with comprehensive results returned in 72 hours.
- Clinical Whole Genome Sequencing Service Clinical whole genome sequencing (WGS) analysis of cancer DNA to identify targeted therapies with results returned within 48 hours, available at one of only two U.S. centers offering this service.
- HopeLLM AI Documentation Tool AI documentation platform built on Microsoft Azure that processes clinical documentation to reduce administrative burden, cutting patient onboarding review time from hours to minutes across 150,000+ annual new patients.
- Hope Pathways Clinical Trials Platform Cloud-based clinical trial matching and enrollment platform used across City of Hope's national 39-site clinical trials network, enabling rapid patient enrollment and trial matching.
- Hope Virtual Telehealth Services Televisit appointments available for patients who cannot travel to physical locations, expanding access to City of Hope's cancer care and consultation services across its national footprint.
Quantifiable outcome
- First-patient consent achieved in as few as 11 days post trial activation
- +7 more outcomes
Companies that use City of Hope
Customer profileNamed customers15 records
Segments6 records
Ideal customer profiles3 records
City of Hope technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability11 records
Feature10 records
City of Hope partnerships and signals
Strategic signalScale indicators15 records
Recent moves8 records
Expansion highlights6 records
City of Hope competitors and assessment
Company assessmentMarket position
Competitive moat6 records
Key highlights7 records
Customer concentration
City of Hope social profiles
Digital presenceCity of Hope compliance and trust
Trust signalCompliance5 records
City of Hope financial estimates
Financial estimateRevenue estimate
Valuation estimate
City of Hope leadership team
Management profileNumber of profiles
Profiles4 records
City of Hope subsidiaries and ownership
Company hierarchySubsidiaries6 records
City of Hope funding detail
Funding detailFunding overview
Funding rounds2 records
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
City of Hope M&A and investment
M&A and investmentM&A2 records
Investments3 records
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about City of Hope
What does City of Hope do?
City of Hope is a nonprofit cancer research and treatment organization that delivers comprehensive cancer care—including surgery, chemotherapy, radiation oncology, immunotherapy, cellular therapy, and targeted therapy—through a national network of hospitals and outpatient clinics across California, Arizona, Illinois, and Georgia. The organization also conducts approximately 800 active clinical studies through its national clinical trials platform and operates a bone marrow transplant program that has performed over 20,000 procedures since 1976, supported by affiliated research institutes such as Beckman Research Institute and TGen.
Is City of Hope a public or private company?
City of Hope is a private company. It is classified as nonprofit foundation owned and is currently operating.
When was City of Hope founded?
City of Hope was founded in 1913. It employs 5,001 to 10,000 people.
Where is City of Hope based?
City of Hope is headquartered in Duarte, United States, in the North America region.
How does City of Hope make money?
Five revenue lines are on record. Patient Care and Treatment Services are the primary driver. The others are clinical Research and Trials, biotechnology and Pharmaceutical Partnerships, philanthropy and Donations and intellectual Property Commercialization.
Does City of Hope have an API?
No public API is recorded for City of Hope.
What industry is City of Hope in?
City of Hope's product category is Oncology Healthcare Services. Its primary akta.pro industry code is BPAGACAA, Disease-Specific Research & Support (e.g., Cancer, Diabetes, ALS), with a secondary code of HLAFAAAM, Hospital-Integrated Cancer Centers (Acute Oncology Programs). Its NAICS code is 622310 and its SIC code is 8060.