Sempre Health
Sempre Health operates a behavior-based dynamic pricing platform that adjusts prescription copays based on refill adherence, serving health plans, PBMs, and pharmaceutical manufacturers targeting commercially insured and Medicare members with chronic conditions.
- Company typePrivate
- Founded2017
- HeadquartersSan Francisco, United States
- Headcount11–50
- GTM typeB2B
- OfferingSoftware
What Sempre Health does
Sempre Health is a San Francisco-based digital health company that operates a behavior-based dynamic pricing platform for prescription medications. The platform dynamically adjusts patient copay costs based on adherence behavior — patients who refill on time receive growing discounts over time, while those who refill late pay more — with discounts applied automatically at the point of sale at retail pharmacies. Members enroll via SMS using a four-letter code with no app, download, or account required, and receive text reminders with expected copay amounts before each refill. The company holds a patent on its automatic refill submission technology and offers a real-time web analytics dashboard for health plan partners.
The company's two-sided business model aligns pharmaceutical manufacturers, health plans/PBMs, and patients. Pharmaceutical manufacturers fund the discounts in exchange for improved adherence, longer therapy duration, and guaranteed exclusion from copay accumulator and maximizer programs (ensuring 100% of manufacturer dollars reach patients). Health plans and PBMs contract with Sempre to deliver the affordability and adherence program to their members, targeting chronic conditions in diabetes, cardiovascular, and respiratory therapeutic areas. The program is free to members and distributed exclusively through channel partners — health plans, PBMs, and manufacturer partnerships — not directly to consumers.
As of 2026, Sempre reports reaching 125+ million eligible commercially insured lives across the United States, has raised approximately $45.5M in disclosed venture funding, and operates with 11-50 employees. Key partnerships include Blue Cross Blue Shield of North Carolina (flagship pilot with 19,500+ patients), Blue Shield of California, UPMC Health Plan, Regence, Prime Therapeutics (PBM for nationwide expansion), Navitus, and manufacturers including Novo Nordisk and Organon. The company recently expanded into Medicare populations and launched in-store location-based savings notifications via smartphone digital wallet integration.
Sempre Health firmographics
Firmographics- Name
- Sempre Health
- Legal name
- Sempre Health, Inc.
- Website
- https://semprehealth.com
- Company type
- Private
- Founded year
- 2017
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Sempre Health operates a behavior-based dynamic pricing platform that adjusts prescription copays based on refill adherence, serving health plans, PBMs, and pharmaceutical manufacturers targeting commercially insured and Medicare members with chronic conditions.
- Ownership category
- akta.pro rank
Sempre Health industry classification
Industry- Product category
- Digital Health / Pharmacy Benefit Technology
- NAICS
- Pharmacy Benefit Management and Other Third Party Administration of Insurance and Pension Funds (524292)
- SIC
- Hospital & Medical Service Plans (6324)
- akta.pro primary industry
- Medication Pricing, Copay Assistance & Patient Financial Support Tools (HLACAKAN)
- akta.pro secondary industries
- Medication Adherence, Packaging & Fulfillment Services (Blister/Unit-Dose) (HLAFALAJ), Chronic Condition Management & Remote Monitoring (e.g., diabetes, HTN) (HLALADAD)
Keywords
Where Sempre Health is headquartered
LocationHeadquarters
- HQ city
- San Francisco
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Sempre Health business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Technology or R&D, Personnel, Marketing or Sales, Operations, Others
Revenue model
- Manufacturer-funded discounts: Sempre contracts with pharmaceutical manufacturers to provide discounts to health plan members. Manufacturers fund the discounts in exchange for improved adherence, longer therapy duration, and guaranteed 100% of dollars reaching patients without accumulator/maximizer interference.
- Health plan/PBM partnerships: Contracts with payers (health plans and PBMs) who want to improve affordability and adherence for branded medications. Health plans select formulary-aligned brands and fund the program structure, paying Sempre for the technology platform, enrollment services, and outcomes delivery.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Freemium | Pay-as-you-go | Free member benefit through health plan partnerships |
Go-to-market motion1 record
Distribution channels3 records
Marketing channels9 records
Sempre Health product offering
Product offeringCore offering
Sempre Health operates a behavior-based dynamic pricing platform that adjusts patient copays based on medication refill adherence. The platform enrolls members via SMS, delivers automatic point-of-sale pharmacy discounts that grow with on-time refills, and provides real-time analytics dashboards to health plan partners. It aligns pharmaceutical manufacturers, payers, and patients to improve medication affordability and adherence for chronic conditions such as diabetes, cardiovascular disease, and asthma.
Product overview
Sempre Health offers a single, unified behavior-based medication pricing platform centered on dynamically adjusting patient copay costs based on adherence behavior. The platform consists of an SMS-based enrollment and reminder system, a pharmacy point-of-sale discount delivery mechanism, a real-time analytics dashboard for health plan partners, and a manufacturer affordability module — all aligned to drive medication adherence in cardiovascular, diabetes, and respiratory therapeutic areas. The company has also launched in-store location-based savings notifications (2025) and expanded into Medicare populations (2024), with clinical outcomes validated through managed care case studies.
Differentiator
Problem solved
Functional benefit
Products and services
- Behavior-Based Medication Pricing Platform A digital health platform that dynamically adjusts patient copay costs based on medication adherence behavior, rewarding on-time prescription refills with growing discounts over time. The platform aligns health plans, pharmaceutical manufacturers, and patients to improve medication affordability and adherence in cardiovascular, diabetes, and respiratory therapeutic areas.
- Health Plan Real-Time Analytics Dashboard
Quantifiable outcome
- 45-65% reduction in patients' out-of-pocket medication costs on average over 12 months
- +9 more outcomes
Companies that use Sempre Health
Customer profileNamed customers8 records
Segments4 records
Ideal customer profiles3 records
Sempre Health technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
Sempre Health partnerships and signals
Strategic signalPartnerships
13 partnerships are on record, tiered core, flagship and minor.
- RegencecoreHealth plan partnership (2026) for commercial members covering medications for chronic conditions including diabetes, heart disease, and asthma. Regence members receive invitations after employer group annual renewal.
- Prime TherapeuticsflagshipPBM expanding Sempre's behavior-based pricing model nationwide following successful pilot with Blue Cross NC (19,500+ patients, $4.7M savings, 70,000+ prescription fills). This is a core strategic partnership enabling national distribution through Prime's commercial client base.
- Blue Cross Blue Shield of North CarolinaflagshipPilot program launched in 2022 that enrolled 19,500+ patients, supported 70,000+ prescription fills, generated $4.7M in member savings, achieved NPS of 98, and increased adherence by 15 percentage points. Results served as proof of concept for Prime Therapeutics nationwide expansion.
- UPMC Health PlancoreExpanded partnership launched in 2018 and further expanded in 2020 to better serve patients with diabetes. UPMC is cited as a thrilled partner with consistently surprised member response.
- Blue Cross Blue Shield of ArizonacoreCollaboration launched February 2021 to further improve medication adherence and affordability for BCBSAZ members.
- Navitus Health SolutionscorePartnership launched July 2020 to help Navitus members save on and adhere to medications through SMS engagement. Navitus is a pharmacy benefit manager.
- Novo NordiskcorePartnership launched April 2018 to improve medication costs for patients with diabetes, focusing on making insulin and other diabetes medications more affordable.
- OrganoncoreCollaboration announced November 2023 to help eligible patients save money and stay on their medication as prescribed. Organon is a global healthcare company focused on women's health.
- MaxorPlusminorPartnership launched November 2018 to lower patient out-of-pocket costs on prescription drugs through Sempre's discount program.
- AllumaminorHealth plan partner offering Sempre's adherence and affordability programs to their members. Alluma provides technology solutions for health plans.
- Blue Care Network of MichiganminorHealth plan (BCBS affiliate) partnered with Sempre to offer behavior-based medication pricing to members.
- Ambetter HealthminorHealth plan partner offering Sempre's medication affordability and adherence program to eligible members.
- Blue Shield of CaliforniacorePresented research at AMCP national meeting (April 2024) demonstrating that Sempre's program improves medication adherence and clinical outcomes for BSC members.
Scale indicators15 records
Recent moves6 records
Expansion highlights6 records
Sempre Health competitors and assessment
Company assessmentDirect peers
- AdhereHealth: AdhereHealth provides medication adherence solutions and pharmacy-related services to health plans, combining predictive analytics with outreach to improve adherence for chronic disease patients. It is comparable to Sempre because it sells into the same payer/PBM buyer, targets the same chronic-condition populations, and pursues improved PDC as the primary outcomes metric.
- RxAnte: RxAnte is a medication adherence analytics and intervention platform serving health plans and PBMs. It is the most direct analog to Sempre Health's adherence-focused, payer-facing analytics and intervention model, with both companies targeting PDC improvement through predictive analytics and targeted patient engagement.
- PharmaCord: PharmaCord is a patient access and affordability company that delivers copay assistance, patient services, and adherence support on behalf of pharmaceutical manufacturers. It is comparable to Sempre because both operate manufacturer-funded patient affordability programs designed to bypass accumulator programs and drive therapy adherence, and both serve as intermediaries between manufacturers and the payer channel.
- RxSense: RxSense is a healthcare technology company offering enterprise pharmacy benefits technology and consumer-facing prescription savings through SingleCare. It is comparable to Sempre because it operates at the intersection of PBM technology, manufacturer-funded savings, and consumer medication affordability — although with a consumer-direct savings layer (SingleCare) that Sempre does not currently offer.
- Capital Rx: Capital Rx operates a modern, technology-first PBM (Judi Health) with transparent pricing and value-based contracts for health plans and employers. It is comparable to Sempre because it is a tech-enabled PBM challenger focused on improving pharmacy benefit affordability and outcomes, with overlapping buyer relationships in Blues plans and self-funded employers.
- Rx Savings Solutions: Rx Savings Solutions (acquired by McKesson) provides prescription savings and adherence solutions primarily to health plans and employer-sponsored populations, identifying lower-cost alternatives and driving member engagement. It is comparable to Sempre because it operates in the medication affordability and adherence space with payer channel distribution and member-facing engagement tools.
- Arrive Health: Arrive Health (formerly RxRevenge) delivers real-time pharmacy benefit and cost information to prescribers at the point of prescribing, integrated with EHR workflows. It is comparable to Sempre because it operates in the medication affordability and benefit transparency space, connecting payers, PBMs, and providers to drive better medication selection and adherence.
Broad incumbents
- GoodRx: GoodRx is a publicly traded consumer prescription savings platform that connects consumers with discounted pricing and a telemedicine platform through GoodRx Care. It is comparable to Sempre as a broader incumbent in the medication affordability space with significantly larger scale, though it serves consumers directly and through a different business model (consumer marketplace rather than behavior-based payer channel).
- OptumRx: OptumRx is the PBM arm of UnitedHealth Group and one of the three largest PBMs in the United States, serving health plans, employers, and government programs. It is comparable to Sempre as a broad incumbent that administers pharmacy benefits at massive scale and operates its own copay assistance and adherence programs, competing for both pharma manufacturer dollars and payer relationships.
- CoverMyMeds: CoverMyMeds (a McKesson business) provides electronic prior authorization, benefit verification, and medication access solutions to providers, payers, and pharmacies. It is comparable to Sempre as a broader incumbent in medication access and affordability infrastructure serving payers and manufacturers, with overlapping value propositions around ensuring patients can obtain and stay on prescribed therapies.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Sempre Health social profiles
Digital presenceSempre Health compliance and trust
Trust signalCompliance1 record
Sempre Health financial estimates
Financial estimateRevenue estimate
Valuation estimate
Sempre Health leadership team
Management profileNumber of profiles
Profiles3 records
Sempre Health funding detail
Funding detailFunding overview
Funding rounds4 records
Investors10 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Sempre Health M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Sempre Health
What does Sempre Health do?
Sempre Health operates a behavior-based dynamic pricing platform that adjusts patient copays based on medication refill adherence. The platform enrolls members via SMS, delivers automatic point-of-sale pharmacy discounts that grow with on-time refills, and provides real-time analytics dashboards to health plan partners. It aligns pharmaceutical manufacturers, payers, and patients to improve medication affordability and adherence for chronic conditions such as diabetes, cardiovascular disease, and asthma.
Is Sempre Health a public or private company?
Sempre Health is a private company. It is classified as venture growth investor backed and is currently operating.
When was Sempre Health founded?
Sempre Health was founded in 2017. It employs 11 to 50 people.
Where is Sempre Health based?
Sempre Health is headquartered in San Francisco, United States, in the North America region.
How does Sempre Health make money?
Two revenue lines are on record. Manufacturer-funded discounts are the primary driver. The others are health plan/PBM partnerships.
Who are Sempre Health's main competitors?
Direct peers on record are AdhereHealth, RxAnte, PharmaCord, RxSense, Capital Rx, Rx Savings Solutions and Arrive Health. Broad incumbents are GoodRx, OptumRx and CoverMyMeds.
Does Sempre Health have an API?
No public API is recorded for Sempre Health.
What industry is Sempre Health in?
Sempre Health's product category is Digital Health / Pharmacy Benefit Technology. Its primary akta.pro industry code is HLACAKAN, Medication Pricing, Copay Assistance & Patient Financial Support Tools, with a secondary code of HLAFALAJ, Medication Adherence, Packaging & Fulfillment Services (Blister/Unit-Dose). Its NAICS code is 524292 and its SIC code is 6324.