Empire Genomics
- Company typePrivate
- Founded2006
- HeadquartersBuffalo, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
Empire Genomics firmographics
Firmographics- Name
- Empire Genomics
- Legal name
- Empire Genomics
- Website
- https://empiregenomics.com
- Company type
- Private
- Founded year
- 2006
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Ownership category
- akta.pro rank
Empire Genomics industry classification
Industry- Product category
- Molecular Diagnostics / Cytogenetics Reagents
- NAICS
- In-Vitro Diagnostic Substance Manufacturing (325413), Analytical Laboratory Instrument Manufacturing (334516), Medical Laboratories (621511)
- SIC
- In Vitro & In Vivo Diagnostic Substances (2835), Laboratory Analytical Instruments (3826), Services-Medical Laboratories (8071)
- akta.pro primary industry
- Molecular Cytogenetics & Genomic Variation Services (Karyotyping/FISH/aCGH/CNV) (HLAGANAJ)
- akta.pro secondary industries
- Molecular Diagnostics & Genomics Laboratories (HLAFAMAE), Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics) (HLAAALAD), Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF)
Keywords
Where Empire Genomics is headquartered
LocationHeadquarters
- HQ city
- Buffalo
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Empire Genomics business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Technology or R&D, Supply Chain, Operations, Marketing or Sales, Infrastructure
Revenue model
- FISH Probes: Sale of fluorescent in situ hybridization probes including manual probes, automated probes, ASR, RUO, and CE-IVD products. Pricing varies by probe type, kit size, and regulatory status (concentrate vs predilute).
- FISH Ancillaries: Supporting reagents including hybridization buffers, wash buffers, pre-treatment kits, DAPI with antifade, and nick translation kits.
- Custom Probe Services: Custom FISH and CISH probe design and manufacturing services, typically delivered within two weeks.
- Full-Service FISH Processing: End-to-end FISH processing services providing adaptable support from sample to signal for laboratories needing outsourced testing.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Unit Pricing | Pay-as-you-go | ASR (Analyte Specific Reagent) probes - Price ranges by kit size |
| Unit Pricing | Pay-as-you-go | Manual FISH probes - Catalog pricing |
| Unit Pricing | Pay-as-you-go | UroFocus FISH Probe - CE-IVD certified product |
| Unit Pricing | Pay-as-you-go | NISH Positive Control Probe - Automated RNA-ISH |
| Unit Pricing | Pay-as-you-go | Summer Promotion - 50% off ancillaries with new probe purchase |
Go-to-market motion2 records
Distribution channels3 records
Marketing channels5 records
Empire Genomics product offering
Product offeringCore offering
Empire Genomics manufactures and sells Fluorescence In Situ Hybridization (FISH) probes, RNA-ISH (NISH) probes, and ancillary reagents used to detect chromosomal abnormalities and gene expression in clinical diagnostics and research laboratories. The company complements its probe catalog (2,000+ items) with automated staining platforms (NeoPATH Pro, Biodot, ONCORE Pro), custom probe design services, and full-service FISH processing for outsourced testing.
Product overview
Empire Genomics offers a comprehensive FISH testing solutions portfolio built around a platform-plus-products architecture. The core offering centers on FISH Probes available in multiple formats (Single Color, Dual Color, Break Apart, Fusion, Control Probes) for detecting chromosomal abnormalities in clinical and research settings. This is complemented by the NISH Probes product line—ready-to-use RNA-ISH research probes powered by HCR™ Pro technology—for the NeoPATH Pro automation platform. Supporting the probe portfolio are FISH Ancillaries (hybridization buffers, pre-treatment kits, wash buffers) and Custom FISH Probe Design services enabling any-target probe creation. The company also provides Full-Service FISH Processing as a laboratory service option. Automation is enabled through three dedicated platforms: NeoPATH Pro for tissue FISH, Biodot for hematology applications, and ONCORE Pro® for urine cytology. The portfolio spans over 2,000 probe catalog items, 50+ automated probes, and is backed by an extensive BAC library originating from the Human Genome Project.
Differentiator
Problem solved
Functional benefit
Brands
- NISH (Novel ISH): Ready-to-use RNA in situ hybridization probes for the NeoPATH Pro automated staining platform, powered by HCR™ Pro technology.
- NeoPATH Pro
- Swish Probes
Products and services
- FISH Probes Fluorescence In Situ Hybridization (FISH) probes for detecting chromosomal abnormalities, available in multiple formats including Single Color, Dual Color, Break Apart, Fusion, and Control Probes for clinical and research applications across FFPE, cytology, and hematology samples.
- NISH Probes (RNA-ISH) Ready-to-use RNA-ISH research probes powered by HCR™ Pro chemistry for the NeoPATH Pro automated staining platform. Includes HPV probes, ISH probes (KAPPA, LAMBDA, EBER, CMV, ERBB2, ALBUMIN), and control probes for gene expression mapping and biomarker characterization with run times as little as 5.5 hours.
- NeoPATH Pro Automated Staining Platform Fully automated staining platform for tissue FISH testing that delivers automated FISH workflows from start to finish, consolidating ISH, IHC, and FISH workflows on a single instrument for clinical and research laboratories.
- Biodot Automation Platform Automation platform designed for hematology (HEME) applications, enabling automated FISH workflows for blood-related diagnostic testing.
- ONCORE Pro® Automated Staining Platform Automated staining platform designed for urine cytology applications, providing automated FISH workflows for urological diagnostic testing.
- FISH Ancillaries Essential supporting reagents including SwiftFISH® Fast Hybridization Buffer, DAPI w/ Antifade, Wash Buffers, FFPE Pre-Treatment Kit, Cyto Pre-Treatment Kit, Hybridization Buffer, and Nick Translation Kit—designed to enhance the accuracy, efficiency, and quality of FISH and CISH results.
- Custom FISH Probe Design Service Custom probe design service allowing creation of FISH and CISH probes for any target, with design turnaround in two weeks or less, delivered through advanced FISH specialist engagement.
- Full-Service FISH Processing End-to-end FISH processing service providing adaptable outsourced testing support from sample preparation to signal detection for laboratories that need external testing capability.
- PTEN del-TECT™ Four Color FISH Probe Research-use-only four-color FISH assay detecting PTEN gene deletions with flanking controls (WAPAL/BMPR1A, FAS) and CEP10 centromere probe to distinguish true deletions from FFPE artifacts.
Quantifiable outcome
- 5.5-hour turnaround for automated RNA-ISH (NISH) on NeoPATH Pro vs. traditional multi-day workflows
- +2 more outcomes
Companies that use Empire Genomics
Customer profileSegments3 records
Ideal customer profiles3 records
Empire Genomics technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
Empire Genomics partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core and minor.
- Molecular InstrumentscoreEmpire Genomics and Molecular Instruments launched NISH (Navigated ISH) powered by HCR™ Pro technology, described as the largest ready-to-use, fully automated ISH library for research, exclusively available on the NeoPATH Pro automated staining platform. The collaboration aims to address barriers to RNA-ISH adoption including workflow complexity, limited automation, and probe access for research laboratories conducting biomarker and translational research.
- GMED (Notified Body)minorGMED is the Notified Body partner for Empire Genomics IVDR transition, overseeing compliance with EU Regulation 2017/746. This partnership ensures continuous product availability during transition from IVDD to IVDR certification, expected by Q4 2026.
Scale indicators10 records
Recent moves4 records
Expansion highlights5 records
Empire Genomics competitors and assessment
Company assessmentDirect peers
- Abbott Molecular: Abbott Molecular (Vysis) is the historical market leader in FISH probes for oncology and cytogenetics, offering a directly overlapping probe portfolio plus bundled instrument platforms. It competes head-to-head with Empire Genomics across clinical diagnostics and cancer center customers.
- ZytoVision: ZytoVision manufactures FISH and CISH probes for clinical diagnostics and research, with a comparable probe catalog and a focus on pathology and cytogenetics applications. It is one of the closest direct competitors to Empire Genomics in mid-sized FISH probe markets.
- MetaSystems: MetaSystems provides FISH probes alongside automated imaging and analysis platforms for cytogenetics. It competes with Empire in the FISH probe consumable market and is especially relevant given Empire's automation platform strategy.
- Cytocell (Revvity): Cytocell, now part of Revvity (formerly PerkinElmer), is a leading FISH probe manufacturer with a deep oncology and hematology portfolio. It directly competes with Empire Genomics for clinical cytogenetics lab customers and offers bundled probe-instrument solutions.
Others
- BioCare Medical: BioCare Medical is the sister/parent entity to Empire Genomics within the Agilent diagnostics group, specializing in IHC and automation. While not a direct FISH competitor, the two share a common owner and overlapping customer base in anatomic pathology labs.
- Leica Biosystems (Danaher): Leica Biosystems, part of Danaher's diagnostics platform, supplies IHC, ISH, and FISH staining instruments and reagents used by pathology labs. It competes with Empire on automation platforms (e.g., vs. NeoPATH Pro) and adjacent reagent categories.
Broad incumbents
- Roche Diagnostics: Roche Diagnostics is a global molecular diagnostics incumbent offering FISH probes (through its Ventana/legacy Roche Molecular portfolio) alongside PCR, NGS, and tissue diagnostics. It competes broadly with Empire at large hospital and reference lab accounts.
- Qiagen: Qiagen is a major molecular diagnostics and sample technologies provider with a portfolio that overlaps Empire's customer base in oncology and translational research labs. While not primarily a FISH competitor, it competes for the same molecular diagnostics budgets.
- Hologic: Hologic operates a molecular diagnostics franchise (including the Diagenode and former Grifols partnership assets) with FISH-adjacent products in cytogenetics and women's health oncology. It competes for the same clinical lab budgets and instrument placements.
- Agilent Technologies: Agilent is the parent conglomerate of Empire Genomics and operates broadly across life sciences instrumentation, diagnostics, and applied markets. While not a direct peer, it is the ultimate parent and provides the strategic and operational backdrop for Empire's competitive positioning.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Empire Genomics social profiles
Digital presenceEmpire Genomics compliance and trust
Trust signalCompliance2 records
Empire Genomics financial estimates
Financial estimateRevenue estimate
Valuation estimate
Empire Genomics leadership team
Management profileNumber of profiles
Profiles4 records
Empire Genomics funding detail
Funding detailFunding overview
Funding rounds3 records
Investors3 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Empire Genomics M&A and investment
M&A and investmentM&A1 record
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Empire Genomics
What does Empire Genomics do?
Empire Genomics manufactures and sells Fluorescence In Situ Hybridization (FISH) probes, RNA-ISH (NISH) probes, and ancillary reagents used to detect chromosomal abnormalities and gene expression in clinical diagnostics and research laboratories. The company complements its probe catalog (2,000+ items) with automated staining platforms (NeoPATH Pro, Biodot, ONCORE Pro), custom probe design services, and full-service FISH processing for outsourced testing.
Is Empire Genomics a public or private company?
Empire Genomics is a private company. It is classified as corporate owned and is currently operating.
When was Empire Genomics founded?
Empire Genomics was founded in 2006. It employs 11 to 50 people.
Where is Empire Genomics based?
Empire Genomics is headquartered in Buffalo, United States, in the North America region.
How does Empire Genomics make money?
Four revenue lines are on record. FISH Probes are the primary driver. The others are FISH Ancillaries, custom Probe Services and full-Service FISH Processing.
Who are Empire Genomics's main competitors?
Direct peers on record are Abbott Molecular, ZytoVision, MetaSystems and Cytocell (Revvity). Others are BioCare Medical and Leica Biosystems (Danaher). Broad incumbents are Roche Diagnostics, Qiagen, Hologic and Agilent Technologies.
Does Empire Genomics have an API?
No public API is recorded for Empire Genomics.
What industry is Empire Genomics in?
Empire Genomics's product category is Molecular Diagnostics / Cytogenetics Reagents. Its primary akta.pro industry code is HLAGANAJ, Molecular Cytogenetics & Genomic Variation Services (Karyotyping/FISH/aCGH/CNV), with a secondary code of HLAFAMAE, Molecular Diagnostics & Genomics Laboratories. Its NAICS code is 325413 and its SIC code is 2835.