NCIRE

What NCIRE does

NCIRE (Northern California Institute for Research and Education, Inc.) is a 501(c)(3) nonprofit research institute established in 1988 under congressional legislation that authorized VA medical centers to establish nonprofit research corporations. It operates as a scientific community of clinicians and researchers based at the San Francisco VA Health Care System (SFVAHCS) in San Francisco, California, in long-standing partnership with the University of California San Francisco (UCSF). The institute's mission is to translate research into clinical practice for U.S. military Veterans and the broader public by developing novel treatments for conditions that disproportionately affect Veterans, including PTSD, traumatic brain injury, cardiovascular disease, Alzheimer's disease, diabetes, infectious diseases, and mental health conditions.

NCIRE supports the work of over 200 principal investigators and manages the largest competitively funded research program in the VA system, with $105.6 million in research expenditures at SFVAHCS. Its core services include clinical trial management, IRB submission and regulatory support, data management and biostatistics, dedicated research pharmacy and laboratory services, and subject compensation administration. The institute runs five nationally recognized Centers of Excellence (Epilepsy, Cardiac Surgery, PTSD, HIV, and Renal Dialysis) and a research portfolio spanning 40+ therapeutic areas, with infrastructure designed to support Phase II-IV clinical trials and real-world evidence studies.

The revenue model is a hybrid of federal research grants (NIH, DoD, VA), industry-sponsored clinical trial partnerships with pharmaceutical and biotech companies (managed through master CDAs and CRADAs), and tax-deductible charitable donations. NCIRE is governed by an uncompensated Board of Directors and led by CEO Rebecca Rosales, MBA, CRA. Go-to-market is primarily relationship-driven: the Office of Sponsored Research engages industry sponsors directly, while the website, DNA Newsletter, and a multi-platform social media presence support broader outreach. The SFVAHCS patient base of 124,837+ unique Veterans across Northern California is the core asset that NCIRE monetizes for both federally and industry-funded research.

Name

NCIRE

Legal name

Northern California Institute for Research and Education, Inc.

Website

https://ncire.org

Company type

Private

Founded year

1988

Operating status

Operating

Headcount range

101–250 employees

Short description

NCIRE is a 501(c)(3) nonprofit research institute established in 1988 that supports over 200 principal investigators conducting Veterans' health research at the San Francisco VA Health Care System and UCSF, managing the largest VA research program at $105.6M in expenditures.

Ownership category

akta.pro rank

Product category

Clinical Research Services

NAICS

Scientific Research and Development Services (5417), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Services-Commercial Physical & Biological Research (8731), Services-Testing Laboratories (8734)

akta.pro primary industry

Non-Communicable Disease Prevention & Chronic Disease Programs (BPAIAJAI)

akta.pro secondary industry

Non-Communicable Diseases (NCDs) & Mental Health Programs (BPADAIAK)

Keywords

• Veterans health research
• Clinical trial services
• Nonprofit research institute
• Biomedical research services
• Federal research grants

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Federal Research Grants: NCIRE participates in NIH and DoD-funded programs, supporting over 200 principal investigators with $105.6 million in research expenditures. The organization manages federally funded research programs as a VA-affiliated nonprofit corporation established under 1988 congressional legislation.
2. Industry Clinical Trial Partnerships: Industry collaborations including Phase II-IV clinical trials and real-world evidence studies. The organization has established Master CDA and CRADA agreements with major pharmaceutical companies for conducting sponsored clinical research.
3. Donations and Charitable Contributions: NCIRE is a 501(c)(3) nonprofit organization with Tax ID #94-3084159. All gifts are tax deductible as noted on the organization's website.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

Core offering

NCIRE is a 501(c)(3) nonprofit research institute that supports Veterans' health research at the San Francisco VA Health Care System (SFVAHCS). It provides clinical trial management, regulatory and IRB support, data management and biostatistics, and research infrastructure for over 200 principal investigators. The institute partners with pharmaceutical and biotech companies on Phase II-IV clinical trials and real-world evidence studies, and collaborates academically with UCSF.

Product overview

NCIRE (Northern California Institute for Research and Education) is a nonprofit research institute established in 1988 that operates as a scientific community of clinicians and researchers partnering with the San Francisco VA Health Care System and UCSF. The organization does not offer commercial software products; instead, it provides research support services including clinical trial management, regulatory compliance, data management, and biostatistics for over 200 principal investigators. NCIRE's core offerings include the DNA Newsletter publication, Industry Research Partnership Program for pharma/biotech collaborations, Clinical Trial Support Services, a multi-disciplinary Research Areas Portfolio spanning 40+ therapeutic areas, and Centers of Excellence in specialty areas such as Epilepsy, Cardiac Surgery, PTSD, HIV, and Renal Dialysis.

Differentiator

Problem solved

Functional benefit

Products and services

• Industry Research Partnership Program Structured collaboration program enabling pharmaceutical and biotech companies to conduct clinical research at SFVAHCS, leveraging access to diverse Veteran patient populations, established trial infrastructure, and academic partnership with UCSF. For pharmaceutical and biotech sponsors seeking clinical trial sites and Veterans health research collaborations.
• Clinical Trial Support Services Dedicated clinical trial support including experienced RN study coordinators, regulatory teams, efficient IRB pathways, master CDA and CRADA agreements, and dedicated research pharmacist and laboratory services. For pharmaceutical and biotech sponsors conducting Phase II-IV clinical trials and real-world evidence studies.
• Research Areas Portfolio Multi-disciplinary research program spanning 40+ therapeutic areas including Alzheimer's Disease, cardiovascular disease, depression, diabetes, infectious diseases, oncology, PTSD, TBI, and other conditions affecting Veterans. For federal research agencies, pharmaceutical sponsors, and academic collaborators.
• Centers of Excellence Nationally recognized specialty centers including Epilepsy, Cardiac Surgery, PTSD, HIV, and Renal Dialysis that provide specialized trial capabilities and cutting-edge research programs. For sponsors seeking specialized clinical trial capabilities in these therapeutic areas.

Quantifiable outcome

• Largest VA Research Program: $105.6 million in research expenditures at SFVAHCS
• +1 more outcomes

Named customers2 records

Segments3 records

Ideal customer profiles2 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Three partnerships are on record, tiered minor and core.

• Roam RoboticsminorStrategic or Co-development Partner · 8 December 2021Partnership to study the impact of Roam Robotics' robotic wearable technology on the Veteran population. NCIRE and SFVAHCS collaborate on research evaluating the effectiveness of robotic exoskeleton devices for Veteran mobility and rehabilitation.
• San Francisco VA Health Care System (SFVAHCS)coreStrategic or Co-development Partner · 1 January 1988Primary institutional partner where NCIRE-supported scientists and clinicians conduct Veterans' health research. SFVAHCS hosts the largest competitively funded research program in the VA system ($105.6M in research expenditures). The partnership includes jointly recruited physicians and integrated training and research programs.
• UCSF School of MedicinecoreStrategic or Co-development Partner · 1 January 1970SFVAHCS has been affiliated with UCSF School of Medicine for over 50 years. Partnership includes jointly recruited physicians and integrated training and research programs across Schools of Medicine, Nursing, Dentistry, and Pharmacy. This brings leading academic expertise and infrastructure to industry trials conducted at SFVAHCS.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

Market position

Strengths4 records

Competitive moat6 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/ncireveterans
• Facebookfacebook.com/NCIREveterans
• LinkedInlinkedin.com/company/ncire
• Instagraminstagram.com/ncireveterans

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds1 record

Investors1 record

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M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about NCIRE