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Ivantis

Full company profile

uuid0002kh1

Namestring
Ivantis
Websiteurl
ivantisinc.com
Company typeenum
Private
Founded yearint
2007
Descriptiontext

Ivantis is a clinical and commercial-stage medical device company that developed the Hydrus Microstent, a micro-invasive glaucoma surgery (MIGS) implant intended for adult patients with mild-to-moderate primary open-angle glaucoma undergoing cataract surgery. The Hydrus Microstent is an 8 mm nitinol scaffold designed to dilate and scaffold approximately 90 degrees of Schlemm's canal, restoring physiological aqueous outflow through the eye's natural drainage pathway rather than creating a synthetic bypass. The company monetizes through direct sales of the single-use implant to ophthalmic surgeons and ambulatory surgical centers, primarily in the United States with selected international markets reached prior to the Alcon transaction. Ivantis was founded in 2007 and is headquartered in Irvine, California; the FDA approval of Hydrus was secured in August 2018 on the strength of the HORIZON pivotal RCT (556 patients, with reported ~80% medication-free retention at five years and AAO's 2020 highest MIGS data quality rating). In 2022, Ivantis was acquired by Alcon and the Hydrus platform is now positioned within Alcon's surgical-vision portfolio alongside complementary phacoemulsification and selective laser trabeculoplasty systems, materially expanding its global distribution reach.

Short descriptiontext

Ivantis is a medical device company that developed the Hydrus Microstent, a nitinol MIGS implant that scaffolds Schlemm's canal to lower intraocular pressure in adult primary open-angle glaucoma patients undergoing cataract surgery; acquired by Alcon in 2022.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
101–250
akta.pro rankint
HeadquartersIrvine, United States
HQ citystring
Irvine
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Keyword5 values
glaucoma surgery devices, MIGS implants, intraocular pressure management, ophthalmic medical devices, canal-based microstent
Industry2 codes
1Glaucoma Diagnostics & Surgical Devices (Tonometry, Gonioscopy, MIGS, Drainage Implants, Laser Trabeculoplasty)
CodeHLAHAJAIPrimaryYes
2Glaucoma Specialists
CodeHLAKAKAGPrimaryNo
NAICS code1 code
  • Electromedical and Electrotherapeutic Apparatus Manufacturing334510
SIC code1 code
  • Surgical & Medical Instruments & Apparatus3841
Product category
Ophthalmic Medical Devices
Social media profiles1 record
Marketing channels4 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels2 records

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components5 values
Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

Ivantis developed and commercialized the Hydrus Microstent, a canal-based Microinvasive Glaucoma Surgery (MIGS) device made of nitinol (nickel-titanium alloy) that is approximately the size of an eyelash. The device spans approximately 90° of Schlemm's canal, dilating and scaffolding it to bypass the trabecular meshwork and restore aqueous humor outflow, reducing intraocular pressure (IOP) in adult patients with mild to moderate primary open-angle glaucoma undergoing cataract surgery.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 5 values shown
  • 59% of Hydrus Microstent patients remained medication-free at 5 years (n=308)
+4 more records
Product and service1 record
1Hydrus® Microstent
Scale indicator3 records

Each record includes

Type, Value, Description, Source

Partnership1 partner
Strategic tierCoreTypeOEM/ Whitelabel/ Licensing Partner
Description

Ivantis developed and commercialized the Hydrus Microstent, a canal-based MIGS device for glaucoma surgery. Alcon acquired Ivantis in 2022 and now manufactures, markets, and distributes the Hydrus Microstent globally through its surgical ophthalmology channel. The acquisition provided Alcon with one of the most clinically validated MIGS devices and expanded its glaucoma portfolio. Alcon operates the MyAlcon Professional platform for ordering and customer management.

Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
TypeBroad incumbent
Description

Alcon is the global leader in ophthalmic surgery and acquired Ivantis in 2022. It now manufactures and distributes Hydrus through its surgical sales force and bundles it with Voyager DSLT, making it both the parent and a broad-incumbent channel/competitor for other MIGS devices.

TypeBroad incumbent
Description

AbbVie's Allergan franchise historically held the XEN Gel Stent MIGS asset. As a broad incumbent in ophthalmology and glaucoma pharmaceuticals, it competes with the Hydrus platform through alternative MIGS options and a large eye-care sales infrastructure.

TypeDirect peer
Description

Glaukos pioneered MIGS and is the dominant player with the iStent family of trabecular bypass stents. It is the most directly comparable peer to Ivantis/Hydrus, competing head-to-head in combined cataract-MIGS procedures for mild-to-moderate POAG.

TypeDirect peer
Description

Sight Sciences commercializes the OMNI Surgical System, a MIGS device that combines trabeculotomy and viscodilation. It targets the same mild-to-moderate POAG segment as Hydrus and competes for surgeon adoption in combined and standalone MIGS procedures.

TypeEmerging player
Description

MicroOptx is developing the Beacon Aqueous Microshunt, an ab externo glaucoma drainage device. It is an emerging player in surgical glaucoma targeting a related but different mechanism, comparable to Ivantis as a glaucoma-focused medtech developer.

TypeEmerging player
Description

iSTAR Medical develops the MINIject supraciliary MIGS implant for glaucoma. It is an emerging MIGS player pursuing a different outflow pathway (suprachoroidal) but addressing the same POAG patient population as Hydrus.

TypeEmerging player
Description

New World Medical manufactures the Kahook Dual Blade and other glaucoma surgical instruments. It is an emerging competitor in angle-based MIGS and ab interno procedures, overlapping with Hydrus's surgical glaucoma surgeon customer base.

TypeEmerging player
Description

NovaEye Medical develops the iTrack microcatheter for canaloplasty and ABiC procedures. It competes in the angle-based surgical glaucoma space and targets many of the same glaucoma surgeons as Hydrus.

TypeBroad incumbent
Description

Carl Zeiss Meditec is a broad incumbent in ophthalmic surgical equipment and diagnostics with glaucoma-relevant offerings (e.g., laser and imaging systems). It is a comparable peer through its surgical channel reach to the same glaucoma specialist customers.

TypeBroad incumbent
Description

Bausch + Lomb is a broad ophthalmic incumbent with surgical, pharmaceutical, and contact lens franchises. It competes for surgeon mindshare and OR shelf space across glaucoma and adjacent ophthalmic surgical categories.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses5 records

Each record includes

Headline, Details, Source

Competitive moat5 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights7 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment1 record

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile1 record

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail

Docs URL, Description

AI maturity
App detail

Has app

Feature4 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles8 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds7 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors16 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Ivantis

Ophthalmic Medical Devicesivantisinc.com

Ivantis is a medical device company that developed the Hydrus Microstent, a nitinol MIGS implant that scaffolds Schlemm's canal to lower intraocular pressure in adult primary open-angle glaucoma patients undergoing cataract surgery; acquired by Alcon in 2022.

What Ivantis does

Ivantis is a clinical and commercial-stage medical device company that developed the Hydrus Microstent, a micro-invasive glaucoma surgery (MIGS) implant intended for adult patients with mild-to-moderate primary open-angle glaucoma undergoing cataract surgery. The Hydrus Microstent is an 8 mm nitinol scaffold designed to dilate and scaffold approximately 90 degrees of Schlemm's canal, restoring physiological aqueous outflow through the eye's natural drainage pathway rather than creating a synthetic bypass. The company monetizes through direct sales of the single-use implant to ophthalmic surgeons and ambulatory surgical centers, primarily in the United States with selected international markets reached prior to the Alcon transaction. Ivantis was founded in 2007 and is headquartered in Irvine, California; the FDA approval of Hydrus was secured in August 2018 on the strength of the HORIZON pivotal RCT (556 patients, with reported ~80% medication-free retention at five years and AAO's 2020 highest MIGS data quality rating). In 2022, Ivantis was acquired by Alcon and the Hydrus platform is now positioned within Alcon's surgical-vision portfolio alongside complementary phacoemulsification and selective laser trabeculoplasty systems, materially expanding its global distribution reach.

Ivantis firmographics

Firmographics
Name
Ivantis
Website
https://ivantisinc.com
Company type
Private
Founded year
2007
Operating status
Operating
Headcount range
101–250 employees
Short description
Ivantis is a medical device company that developed the Hydrus Microstent, a nitinol MIGS implant that scaffolds Schlemm's canal to lower intraocular pressure in adult primary open-angle glaucoma patients undergoing cataract surgery; acquired by Alcon in 2022.
Ownership category
akta.pro rank

Ivantis industry classification

Industry
Product category
Ophthalmic Medical Devices
NAICS
Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)
SIC
Surgical & Medical Instruments & Apparatus (3841)
akta.pro primary industry
Glaucoma Diagnostics & Surgical Devices (Tonometry, Gonioscopy, MIGS, Drainage Implants, Laser Trabeculoplasty) (HLAHAJAI)
akta.pro secondary industry
Glaucoma Specialists (HLAKAKAG)

Keywords

  • Glaucoma surgery devices
  • MIGS implants
  • Intraocular pressure management
  • Ophthalmic medical devices
  • Canal-based microstent

Where Ivantis is headquartered

Location

Headquarters

HQ city
Irvine
HQ country
United States
HQ region
North America

Markets served

Ivantis business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain

Distribution channels2 records

Marketing channels4 records

Ivantis product offering

Product offering

Core offering

Ivantis developed and commercialized the Hydrus Microstent, a canal-based Microinvasive Glaucoma Surgery (MIGS) device made of nitinol (nickel-titanium alloy) that is approximately the size of an eyelash. The device spans approximately 90° of Schlemm's canal, dilating and scaffolding it to bypass the trabecular meshwork and restore aqueous humor outflow, reducing intraocular pressure (IOP) in adult patients with mild to moderate primary open-angle glaucoma undergoing cataract surgery.

Differentiator

Problem solved

Functional benefit

Products and services

  • Hydrus® Microstent

Quantifiable outcome

  • 59% of Hydrus Microstent patients remained medication-free at 5 years (n=308)
  • +4 more outcomes

Companies that use Ivantis

Customer profile

Segments1 record

Ideal customer profiles1 record

Ivantis technology and API

Technology

Technology focussed Yes

API detail

API docs
API detail

Core technology

AI maturity

App detail

Feature4 records

Ivantis partnerships and signals

Strategic signal

Partnerships

One partnership is on record.

  • AlconcoreOEM/ Whitelabel/ Licensing PartnerIvantis developed and commercialized the Hydrus Microstent, a canal-based MIGS device for glaucoma surgery. Alcon acquired Ivantis in 2022 and now manufactures, markets, and distributes the Hydrus Microstent globally through its surgical ophthalmology channel. The acquisition provided Alcon with one of the most clinically validated MIGS devices and expanded its glaucoma portfolio. Alcon operates the MyAlcon Professional platform for ordering and customer management.

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Ivantis competitors and assessment

Company assessment

Broad incumbents

  • Alcon: Alcon is the global leader in ophthalmic surgery and acquired Ivantis in 2022. It now manufactures and distributes Hydrus through its surgical sales force and bundles it with Voyager DSLT, making it both the parent and a broad-incumbent channel/competitor for other MIGS devices.
  • AbbVie (Allergan Aesthetics / Eye Care): AbbVie's Allergan franchise historically held the XEN Gel Stent MIGS asset. As a broad incumbent in ophthalmology and glaucoma pharmaceuticals, it competes with the Hydrus platform through alternative MIGS options and a large eye-care sales infrastructure.
  • Carl Zeiss Meditec: Carl Zeiss Meditec is a broad incumbent in ophthalmic surgical equipment and diagnostics with glaucoma-relevant offerings (e.g., laser and imaging systems). It is a comparable peer through its surgical channel reach to the same glaucoma specialist customers.
  • Bausch + Lomb: Bausch + Lomb is a broad ophthalmic incumbent with surgical, pharmaceutical, and contact lens franchises. It competes for surgeon mindshare and OR shelf space across glaucoma and adjacent ophthalmic surgical categories.

Direct peers

  • Glaukos Corporation: Glaukos pioneered MIGS and is the dominant player with the iStent family of trabecular bypass stents. It is the most directly comparable peer to Ivantis/Hydrus, competing head-to-head in combined cataract-MIGS procedures for mild-to-moderate POAG.
  • Sight Sciences: Sight Sciences commercializes the OMNI Surgical System, a MIGS device that combines trabeculotomy and viscodilation. It targets the same mild-to-moderate POAG segment as Hydrus and competes for surgeon adoption in combined and standalone MIGS procedures.

Emerging players

  • MicroOptx: MicroOptx is developing the Beacon Aqueous Microshunt, an ab externo glaucoma drainage device. It is an emerging player in surgical glaucoma targeting a related but different mechanism, comparable to Ivantis as a glaucoma-focused medtech developer.
  • iSTAR Medical: iSTAR Medical develops the MINIject supraciliary MIGS implant for glaucoma. It is an emerging MIGS player pursuing a different outflow pathway (suprachoroidal) but addressing the same POAG patient population as Hydrus.
  • New World Medical: New World Medical manufactures the Kahook Dual Blade and other glaucoma surgical instruments. It is an emerging competitor in angle-based MIGS and ab interno procedures, overlapping with Hydrus's surgical glaucoma surgeon customer base.
  • NovaEye Medical: NovaEye Medical develops the iTrack microcatheter for canaloplasty and ABiC procedures. It competes in the angle-based surgical glaucoma space and targets many of the same glaucoma surgeons as Hydrus.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

Ivantis social profiles

Digital presence

Ivantis financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Ivantis leadership team

Management profile

Number of profiles

Profiles8 records

Ivantis funding detail

Funding detail

Funding overview

Funding rounds7 records

Investors16 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Ivantis M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Ivantis

What does Ivantis do?

Ivantis developed and commercialized the Hydrus Microstent, a canal-based Microinvasive Glaucoma Surgery (MIGS) device made of nitinol (nickel-titanium alloy) that is approximately the size of an eyelash. The device spans approximately 90° of Schlemm's canal, dilating and scaffolding it to bypass the trabecular meshwork and restore aqueous humor outflow, reducing intraocular pressure (IOP) in adult patients with mild to moderate primary open-angle glaucoma undergoing cataract surgery.

Is Ivantis a public or private company?

Ivantis is a private company. It is classified as corporate owned and is currently operating.

When was Ivantis founded?

Ivantis was founded in 2007. It employs 101 to 250 people.

Where is Ivantis based?

Ivantis is headquartered in Irvine, United States, in the North America region.

Who are Ivantis's main competitors?

Broad incumbents on record are Alcon, AbbVie (Allergan Aesthetics / Eye Care), Carl Zeiss Meditec and Bausch + Lomb. Direct peers are Glaukos Corporation and Sight Sciences. Emerging players are MicroOptx, iSTAR Medical, New World Medical and NovaEye Medical.

What industry is Ivantis in?

Ivantis's product category is Ophthalmic Medical Devices. Its primary akta.pro industry code is HLAHAJAI, Glaucoma Diagnostics & Surgical Devices (Tonometry, Gonioscopy, MIGS, Drainage Implants, Laser Trabeculoplasty), with a secondary code of HLAKAKAG, Glaucoma Specialists. Its NAICS code is 334510 and its SIC code is 3841.

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Live signals
GlobeNewswireSight Sciences Defeats Invalidity Challenges Filed By Alcon and Ivantis In The U.S. Patent OfficeSight Sciences defeated all four patent invalidity challenges filed by Alcon and Ivantis in the U.S. Patent Office. The Patent Office denied each petition, finding prior art had been presented during examination. A five-day jury trial is scheduled for April 8, 2024.PR NewswireIvantis Announces First Patient Enrolled in Pivotal Clinical Trial Evaluating the Hydrus Microstent in Standalone MIGS for Mild to Moderate GlaucomaIvantis Inc. announced the enrollment of the first patient in the FRONTIER pivotal clinical trial evaluating the Hydrus Microstent as a standalone minimally invasive glaucoma surgery (MIGS) procedure for patients with mild to moderate open-angle glaucoma, without concurrent cataract surgery. The trial will enroll 234 eyes at up to 32 study sites inside and outside the U.S., with primary effectiveness endpoints evaluated at one year and follow-up through two years. The FRONTIER trial builds on positive five-year findings from the HORIZON trial, which demonstrated a 47% reduction in visual field loss and over 60% reduction in subsequent invasive glaucoma surgery, and could expand the device's approved use beyond its current indication limited to use with cataract surgery in the U.S.AlconAlcon to Acquire Ivantis, Inc. and its Hydrus Microstent for Surgical Glaucoma, Strengthening Global Ophthalmology PortfolioAlcon announced its intention to acquire Ivantis, Inc., the developer of the Hydrus Microstent, a minimally invasive glaucoma surgery device. The acquisition, valued at $475 million, aims to strengthen Alcon's surgical glaucoma portfolio and is expected to close in the first quarter of 2022, pending regulatory approval. The Hydrus Microstent has demonstrated strong safety and efficacy, showing potential to significantly impact the glaucoma treatment market.MassDeviceAlcon to acquire Ivantis for $475MAlcon announced its intention to acquire glaucoma surgery device maker Ivantis for $475 million upfront, with potential additional contingent payments. The acquisition aims to bolster Alcon's portfolio by integrating Ivantis' Hydrus Microstent, a device approved in multiple countries for minimally invasive glaucoma surgery. The transaction is expected to close in the first quarter of 2022.Business Wire BlogAlcon to Acquire Ivantis, Inc. and its Hydrus Microstent for Surgical Glaucoma, Strengthening Global Ophthalmology PortfolioAlcon announced its intention to acquire Ivantis, Inc. and its Hydrus Microstent for an upfront consideration of $475 million, with potential additional contingent payments based on future milestones. The transaction aims to strengthen Alcon's global ophthalmology portfolio by integrating the clinically proven minimally invasive glaucoma surgery device into its existing offerings. The deal is anticipated to close in the first quarter of 2022, subject to customary closing conditions including regulatory approval.BenzingaIvantis To Pay $60M In Patent Litigation Settlement With Glaukos - Glaukos (NYSE:GKOS)Glaukos Corp settled a patent infringement lawsuit with Ivantis Inc. over Ivantis' Hydrus Microstent, filed by Glaukos in 2018 in the Central District of California. Ivantis will pay $60 million, $30 million by December 31 and the remainder by December 31, 2022, plus a 10% royalty through April 26, 2025, and mutual licenses. The parties will request dismissal of the trial scheduled for September 28, 2021.PR NewswireHydrus Microstent Now First MIGS Device Proven With 5-Year Pivotal Trial Data; Results Show Over 60% Reduction in Secondary Glaucoma Surgeries, Sustained Reduction in Medication UseIvantis Inc. released five-year pivotal trial data for its Hydrus Microstent, demonstrating a sustained reduction in medication use and over 60% fewer secondary glaucoma surgeries compared to cataract surgery alone. The study, involving 556 patients across nine countries, confirmed the device's long-term safety and efficacy, reinforcing its status as the most evidence-backed minimally invasive glaucoma surgery (MIGS) device.PR NewswireHydrus Microstent Receives Highest Designation of Any MIGS Device as Part of AAO Treatment GuidelinesIvantis Inc. announced that its Hydrus Microstent received a "Level 1, Moderate Quality, Strong Recommendation" designation from the American Academy of Ophthalmology in the 2020 Preferred Practice Pattern treatment guidelines—the highest designation given to any minimally invasive glaucoma surgery (MIGS) device. The company also reported four-year HORIZON pivotal trial data published in Ophthalmology showing that 2.1% of Hydrus patients required subsequent invasive glaucoma surgery versus 6% for cataract surgery alone, and 65% of Hydrus patients remained glaucoma medication-free compared with 41% in the control group. The HORIZON trial is the largest prospective, randomized, controlled study conducted for a MIGS device, enrolling 556 patients across 38 centers in nine countries.PR NewswireIvantis Completes Enrollment of International SPECTRUM Registry for Hydrus MicrostentIvantis Inc. announced the completion of enrollment for SPECTRUM, the world's largest single-device registry in ophthalmology, covering nearly 3,000 eyes treated with the Hydrus Microstent across 50 centers in 19 countries. The registry includes the largest reported series of stand-alone glaucoma cases in MIGS and shows promising three-year data with 29% intraocular pressure reduction. Combined with the HORIZON pivotal trial, Ivantis now has both the largest randomized controlled trial and largest registry in the MIGS space, with the device having received FDA approval and strong clinical adoption over the past year.PR NewswireIvantis Announces Publication of Landmark Comparative MIGS Clinical Trial Results in Leading Ophthalmic JournalIvantis Inc. announced the publication of 12-month COMPARE study results in Ophthalmology, comparing its Hydrus Microstent against two Glaukos iStent devices for standalone MIGS glaucoma treatment. The randomized trial of 152 patients at 12 centers demonstrated superior outcomes for Hydrus Microstent, with 47 percent medication-free versus 24 percent for iStent, and 73 percent achieving at least 20 percent IOP reduction on fewer medications versus 47 percent. The company noted that three of its studies have been accepted into Ophthalmology, the most of any company in the MIGS space, with the 2-year follow-up results recently presented at the American Glaucoma Society meeting.