What Spine Wave does

Spine Wave, Inc. is a privately-held medical device company headquartered in Shelton, Connecticut, founded in 2001, that develops and markets a broad portfolio of spinal surgery implants and biologics for spine surgeons and hospitals in the United States. The company's product offering spans expandable interbody devices (Exceed®, Velocity®, Leva® PX/PF/AF, StaXx® XD/XD Ti/IB), 3D-printed titanium interbody devices manufactured via Direct Metal Laser Sintering (Stronghold® 3D, Stronghold® T, Stronghold® C), minimally invasive and modular pedicle screw systems (Sniper®, Sniper® XT, CapSure® PS3, Salvo® 4.75/5.5/6.0), cervical solutions (Proficient®, Defender®, Paramount®, Ni-Lock®, Accent®), the Annex® Adjacent Level System, and biologics (Tornado® Bioactive Bone Graft Matrix, Tempest® Allograft Bone Matrix, and a demineralized cortical fiber product in limited market release as of April 2025).

Underlying the portfolio are several proprietary technologies: TiCell® Nano Advanced Surface Technology, a patented nano-structured surface applied to the Exceed® and Testa™ TP devices; TiCell® 3D Advanced Surface Technology, a dual-layer lattice mimicking organic cancellous bone used on Stronghold® products; Center Pivot Point Technology on the True Position® and Testa™ TP pivoting spacer systems; and Salvo® Modular Fixation Technology enabling in-situ screw assembly. The company follows a surgeon-driven product-development process, seeding initial surgical cases through key opinion leaders such as Alexander R. Vaccaro and Paul C. Celestre.

Spine Wave generates revenue through direct hardware sales to hospitals and spine surgeons, with no public pricing disclosure. The Tempest® Allograft Bone Matrix is sourced through a manufacturing and distribution partnership with Aziyo Biologics, under which Aziyo processes the allograft and Spine Wave commercializes it. The company has raised approximately $145 million in disclosed equity funding across 2002–2018 from investors including New Enterprise Associates, Canaan Partners, Compass Global Fund, and Acadia Woods Partners, with no disclosed funding round after 2018. Revenue, headcount beyond a 51–100 employee band, and ownership structure are not publicly disclosed.

Name

Spine Wave

Legal name

Spine Wave, Inc.

Website

https://spinewave.com

Company type

Private

Founded year

2001

Operating status

Operating

Headcount range

51–100 employees

Short description

Spine Wave is a privately-held medical device company that develops and markets a broad portfolio of spinal surgery implants and biologics — including expandable and 3D-printed titanium interbody devices, pedicle screw systems, cervical plates, and bone graft matrices — sold directly to spine surgeons and hospitals across the United States.

Ownership category

akta.pro rank

Product category

Spinal Surgery Medical Devices

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112), Medical Equipment and Supplies Manufacturing (3391)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Spine Implants & Motion Preservation (Fusion/Disc/Interspinous) (HLAHAEAC)

akta.pro secondary industries

3D-Printed & Patient-Specific Implants (Custom Ortho/Spine/Cranial) (HLAHAEAJ), Surgical Navigation, Robotics & Patient-Matched Instrumentation (Ortho/Spine) (HLAHAEAL)

Keywords

• Spinal implant devices
• Interbody fusion devices
• Pedicle screw systems
• Cervical spine plates
• Spine biologics products

Headquarters

HQ city

Shelton

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Technology or R&D, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. Medical Device Sales: Spine Wave generates revenue through the sale of proprietary spinal surgery devices and biologics products to hospitals and spine surgeons. The company commercializes multiple technology platforms including expandable interbody devices, cervical plate systems, pedicle screw systems, and bone graft matrices.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

Spine Wave develops, manufactures, and markets proprietary medical devices and biologics for spinal surgery, including expandable interbody devices, 3D-printed titanium implants, cervical plate systems, minimally invasive pedicle screw systems, and bone graft matrices. Products are sold directly to spine surgeons and hospitals in the United States, with surgeon-driven product development aimed at less invasive and more efficient spinal fusion and stabilization procedures.

Product overview

Spine Wave is a medical device company focused on spinal surgery solutions, offering a broad portfolio of interbody devices, pedicle screw systems, cervical plates, biologics, and graft delivery systems. The product portfolio includes expandable interbody devices (Exceed®, Velocity®, Leva® PX/PF/AF, StaXx® XD/IB), 3D-printed titanium interbody devices (Stronghold® 3D/T/C), minimally invasive pedicle screw systems (Sniper®, Sniper® XT, CapSure® PS3, Salvo®), cervical solutions (Proficient®, Defender®, Paramount®, Ni-Lock®, Accent®), the Annex® Adjacent Level System for ASD treatment, biologics (Tornado®, Tempest®), and the GraftMag® Graft Delivery System. The portfolio is organized across Posterior Platform, Anterior Platform, Thoracolumbar, Cervical, and Biologics categories, with proprietary technologies including TiCell® Nano Advanced Surface Technology and TiCell™ 3D Advanced Surface Technology.

Differentiator

Problem solved

Functional benefit

Brands

• TiCell®: Proprietary surface technology used on Spine Wave interbody devices
• Exceed®
• Leva®
• True Position®
• StaXx®
• Stronghold®
• Sniper®
• CapSure®
• Salvo®
• Defender®
• Ni-Lock®
• Paramount®
• Accent®
• Proficient®
• Annex®
• Velocity®
• GraftMag®
• Tornado®
• Tempest®

Products and services

• Exceed® Biplanar Expandable Interbody Device An expandable titanium interbody implant featuring patented TiCell® Nano Advanced Surface Technology with dual taper nose for ease of insertion, biplanar expansion, open architecture, and integrated bone grafting capability, designed for spine surgeons performing interbody fusion procedures.
• Velocity® Expandable Interbody Device A composite expandable interbody implant designed for ease of insertion, optimal implant-to-patient fit, maximized indirect decompression, and maximum pre- and post-bone grafting, intended for spine surgeons performing expandable interbody fusion.
• Leva® PX Interbody Device An expandable titanium interbody cage with a small insertion profile and in-situ expansion, featuring open architecture for maximum bone graft capability, for spine surgeons performing interbody fusion.
• Leva® PF Interbody Device A fixed titanium interbody cage optimized for ease of insertion and maximum bone grafting, with retractable bullet nose and open architecture, intended for spine surgeons performing interbody fusion.
• Leva® AF Stand-Alone ALIF System An all-titanium anterior lumbar interbody fusion (ALIF) system with modular anterior plates and bone screws for integrated and stand-alone vertebral body fixation, featuring a large graft chamber, for spine surgeons performing ALIF procedures.
• Stronghold® T 3D Titanium Interbody Device A pivoting crescent-design 3D-printed titanium interbody device for posterior lumbar interbody fusion manufactured using Direct Metal Laser Sintering with TiCell® 3D advanced surface technology and articulating cage delivery, for spine surgeons.
• Stronghold® 3D Titanium Interbody Device A straight-design 3D-printed titanium interbody device for posterior lumbar interbody fusion manufactured using Direct Metal Laser Sintering with TiCell® 3D advanced surface technology, intended for spine surgeons.
• Stronghold® C 3D Titanium Interbody Device A 3D-printed titanium interbody device for anterior cervical interbody fusion featuring TiCell® 3D advanced surface technology with a dual layer organic lattice structure, designed for spine surgeons performing cervical fusion.
• StaXx® XD Expandable Device An expandable PEEK spacer allowing controlled in-situ distraction in 1mm increments with a low-profile design for less invasive procedures, for spine surgeons performing interbody fusion.
• StaXx® XD Ti Expandable Device An expandable PEEK spacer with titanium coated endplates allowing controlled in-situ distraction in 1mm increments, intended for spine surgeons performing interbody fusion.
• StaXx® IB Expandable Interbody Device A low-profile expandable PEEK interbody implant allowing graft material packing both inside and around the implant, for spine surgeons performing interbody fusion.
• True Position® Pivoting Spacer System A pivoting spacer system using patented Center Pivot Point Technology providing controlled mechanical advantage for accurate interbody spacer positioning with anterior advancement capabilities, intended for spine surgeons performing interbody fusion.
• Testa™ TP Pivoting Spacer System A pivoting spacer system featuring TiCell® Nano Advanced Surface Technology, Center Pivot Point Technology, and nano-structured surface enhancements, designed for transforaminal lumbar interbody fusion (TLIF) surgeries and intended for spine surgeons.
• GraftMag® Graft Delivery System A graft delivery system designed to help surgeons deliver large quantities of bone graft quickly while reducing instrument passes along sensitive patient anatomy, for spine surgeons performing bone grafting procedures.
• Sniper® Spine System A next-generation minimally invasive pedicle screw system with a wireless delivery option for treating degeneration, deformity, tumor, or trauma of the thoracolumbar spine, intended for spine surgeons.
• Sniper® XT Spine System A slim-profile thoracolumbar pedicle screw system with integrated reduction threads and flexible breakaway extended tabs, designed for minimally invasive thoracolumbar fixation for spine surgeons.
• CapSure® PS3 Spine System A top-loading pedicle screw system for treating degeneration, tumor, or trauma of the thoracolumbar spine with maximum polyaxial angulation, intended for spine surgeons.
• Salvo® 4.75 Spine System A low-profile modular pedicle screw system with 4.75mm CoCr rod for both cortical bone trajectory and traditional transpedicular approach, using Salvo® Modular Fixation Technology allowing in situ screw assembly, for spine surgeons.
• Salvo® 5.5/6.0 Spine System A modular pedicle screw system allowing in situ assembly with a tensioned head design, accommodating 5.5 and 6.0mm diameter rods, using Salvo® Modular Fixation Technology, for spine surgeons.
• Proficient® Posterior Cervical Spine System A versatile posterior cervical spine system with three unique screw designs (polyaxial tri-lobe, translational, extended tab) for treating degenerative or complex cases, intended for spine surgeons performing posterior cervical fixation.
• Defender® Anterior Cervical Plate An anterior cervical plate system with a dual Cam-Lock mechanism for stabilization as an adjunct to spinal fusion from C2-T1, intended for spine surgeons performing anterior cervical fusion.
• Paramount® Anterior Cervical Cage A roughened titanium anterior cervical implant with integrated fixation plates featuring threaded deployment mechanism and back-filling grafting technique, intended for spine surgeons performing anterior cervical fusion.
• Ni-Lock® Anterior Cervical Plate System An anterior cervical plate system with a nitinol retention clip one-step locking mechanism preventing screw back-out, intended for spine surgeons performing anterior cervical fusion.
• Accent® Cervical Spacer System A cervical spacer system designed to treat degenerative disc disease from C2-T1 with enhanced visualization through tantalum pins, intended for spine surgeons performing cervical interbody fusion.
• Annex® Adjacent Level System A less invasive solution for adjacent segment disease (ASD) with a rotating CoCr polyaxial hook that secures to existing 5.5mm rod systems, intended for spine surgeons treating adjacent level disease.
• Tornado® Bioactive Bone Graft Matrix A unique combination of mineral, bioactive glass, and collagen processed into strips and moldable pucks for bone grafting procedures, intended for spine surgeons performing spinal fusion.
• Tempest® Allograft Bone Matrix A sterile, ready-to-use allograft bone matrix composed of cancellous and partially demineralized cortical bone with osteoinductive and osteoconductive properties, processed by Aziyo Biologics and distributed by Spine Wave, intended for spine surgeons performing spinal fusion.
• Demineralized Cortical Fiber Product A demineralized cortical fiber bone graft product offered by Spine Wave as part of its spine biologics portfolio, intended for use by spine surgeons in spinal fusion procedures.

Named customers2 records

Segments1 record

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

One partnership is on record.

• Aziyo Biologics Inc.coreTechnology or IntegrationAziyo Biologics Inc. processes the Tempest® Allograft Bone Matrix product, which is then distributed by Spine Wave, Inc. This is a manufacturing and distribution partnership where Aziyo handles processing of the allograft bone matrix and Spine Wave commercializes the product for spinal surgery applications.

Scale indicators4 records

Recent moves4 records

Expansion highlights4 records

Direct peers

• Globus Medical: Globus Medical (now merged with NuVasive) is one of the largest pure-play spine device companies, offering a comparable portfolio of interbody devices, pedicle screw systems, and biologics. Spine Wave competes head-to-head with Globus across expandable interbody and MIS pedicle screw categories.
• Alphatec Spine (ATEC): Alphatec is a US-focused spine surgery pure-play developing lateral approach interbody devices, MIS pedicle screws, and biologics. As a similarly mid-sized, US-centric spine specialist, ATEC is a direct comparable in scale and go-to-market approach.
• Orthofix Medical: Orthofix (which merged with SeaSpine) is a spine and biologics company offering interbody devices, fixation systems, and bone graft products. Spine Wave competes across both the device and biologics categories with Orthofix in US hospitals.

Broad incumbents

• Stryker (Spine division): Stryker operates a significant spine implant franchise alongside much larger orthopedics, neurotechnology, and surgical equipment businesses. Spine Wave's interbody and cervical plate offerings overlap with Stryker's spine portfolio, but Stryker competes as a diversified incumbent with bundled hospital contracts.
• ZimVie (Spine): ZimVie operates a dedicated spine business offering cervical and thoracolumbar solutions including interbody devices and pedicle screws. Spine Wave's cervical plate and interbody portfolio overlaps directly with ZimVie's spine segment.
• Medtronic (Spine & Biologics): Medtronic is the largest spine device manufacturer globally, with extensive cervical, thoracolumbar, interbody, and biologics franchises. Spine Wave's full portfolio competes with Medtronic across virtually every spine category, though as a much smaller player.

Emerging players

• Centinel Spine: Centinel Spine specializes in cervical spine solutions including total disc replacement and standalone interbody devices. Spine Wave's cervical plate and cervical interbody portfolio (Defender®, Paramount®, Ni-Lock®, Accent®) competes in adjacent cervical segments.
• Xtant Medical: Xtant Medical is a smaller spine-focused company emphasizing biologics and fixation. Xtant and Spine Wave both target US hospitals with combined hardware-plus-biologics offerings, making Xtant a relevant emerging comparable.
• Captiva Spine: Captiva Spine is a privately held spine device company offering interbody and MIS pedicle screw solutions. As a similarly scaled private competitor focused on differentiated spine technologies, Captiva represents an emerging private peer in the same niche.

Others

• Aziyo Biologics: Aziyo Biologics is a partner (not a competitor) that processes the Tempest® Allograft Bone Matrix distributed by Spine Wave. Aziyo is an enabling strategic partner in Spine Wave's biologics offering rather than a direct competitor.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/channel/UC1qamV4nSVc77amHwrU3NUQ
• LinkedInlinkedin.com/company/108299
• Instagraminstagram.com/spinewaveinc
• Xx.com/Spinewave

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds8 records

Investors15 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Spine Wave