Bestzyme

What Bestzyme does

Bestzyme is a Chinese industrial biotechnology company founded in 2013 and operating as a wholly-owned subsidiary of Hong Kong Stock Exchange-listed GenScript Biotech Corporation. The company develops and manufactures enzyme preparations and synthetic biology products for four primary B2B application areas: grain processing and biofuel production (starch liquefaction, saccharification, ethanol fermentation), food and beverage (baking, brewing, sugar reduction), animal nutrition and feed (feed efficiency, gut health), and household care and textile (liquid laundry detergents, textile desizing and bleaching). It serves enterprise customers across global markets through offices in Nanjing (headquarters and R&D), Jinan (manufacturing), Shanghai (commercial), Piscataway, New Jersey (North America), and Singapore (Southeast Asia), with active presence at international trade shows reaching 120+ countries.

The company's core technology foundation is the Synesis Synthetic Biology Platform, which combines AI algorithms, CRISPR-based gene editing, and automated experimental platforms with five GRAS-certified microbial expression systems (Aspergillus niger, Aspergillus oryzae, Pichia pastoris, Bacillus subtilis, and Bacillus licheniformis). Bestzyme holds 130+ patent applications including 60+ granted patents globally and operates automated biomanufacturing capacity exceeding 150,000 standard metric tons annually. Over 49% of its workforce holds advanced degrees, supporting a deeply R&D-intensive operation. The product portfolio spans branded series including FastLIQ, LiqFINE, HighDEX, SuperAA, and AlcGEN for grain processing; BestBAKER and Proline Protease for food; Promax, EnerGen Supreme, and HealGen for animal nutrition; PuriWise for household care; and Mellia Brazzein, a zero-calorie sweet protein produced via precision fermentation that received FDA GRAS certification in 2025.

Bestzyme generates revenue primarily through one-time direct sales of enzyme preparations to enterprise customers under quote-based pricing, supplemented by a freemium trial program that allows risk-free product evaluation across all four application categories. Go-to-market combines direct sales teams across three regional offices with participation in major global industry exhibitions including IPPE, IFT First, FENAGRA, Fi Asia Thailand, and FEW. In 2023, the company raised $35 million in Series A financing led by Hillhouse Investment to support growth and synthetic biology expansion, and in 2024-2025 it executed a brand identity refresh and product label and packaging overhaul to position for international scaling.

Name

Bestzyme

Legal name

Nanjing Bestzyme Bio-Engineering Co., Ltd.

Website

https://bestzyme.com

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

101–250 employees

Short description

Bestzyme is a Chinese industrial biotechnology company that manufactures enzyme preparations and synthetic biology products for grain processing, food and beverage, animal nutrition, and household care applications, serving global B2B enterprise customers across more than 120 countries.

Ownership category

akta.pro rank

Product category

Industrial Enzyme Manufacturing

NAICS

Food Manufacturing (311), Starch and Vegetable Fats and Oils Manufacturing (31122), Sugar and Confectionery Product Manufacturing (3113), Biological Product (except Diagnostic) Manufacturing (325414)

SIC

Food And Kindred Products (2000), Sugar & Confectionery Products (2060), Agricultural Prod-Livestock & Animal Specialties (200)

akta.pro primary industry

Enzymes & Processing Aids (Baking, Brewing, Dairy, Meat) (CRADAOAH)

akta.pro secondary industries

Fermentation-Derived Alternative Proteins Manufacturing (Precision Fermentation) (AFAKAGAH), Starch Processing & Sweetener Enzymes (AFAJAIAE), Baking & Flour Treatment Enzymes (AFAJAIAA), Brewing & Distilling Enzymes (AFAJAIAD), Synthetic Biology & Genetic Circuit Design Platforms (pathway engineering, chassis development) (HLAAAIAD)

Keywords

• Industrial enzyme manufacturing
• Synthetic biology products
• Animal feed enzymes
• Grain processing enzymes
• Precision fermentation proteins

Headquarters

HQ city

Jinan

HQ country

China

HQ region

Asia

Offices5 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Technology or R&D

Revenue model

1. Industrial Enzyme Products: Bestzyme generates revenue through sale of industrial enzyme preparations for applications including grain processing (starch/fermentation/ethanol), food & nutrition (baking, brewing), animal nutrition & health, and household care & textile industries.
2. Functional/Synthetic Biology Products: Revenue from next-generation functional proteins and synthetic biology products including Mellia Brazzein sweetener, positioned as high-value differentiated products in the food and beverage industry.

Pricing tiers

Go-to-market motion3 records

Distribution channels2 records

Marketing channels5 records

Core offering

Bestzyme manufactures and sells industrial enzyme preparations and synthetic biology products for B2B customers across grain processing (starch, ethanol, brewing), food & nutrition (baking, sweeteners), animal nutrition & health (feed efficiency, gut health), and household care & textile (laundry, textile processing) industries. The company leverages its proprietary Synesis Synthetic Biology Platform, which combines AI algorithms with automated experimental platforms, to develop enzyme and protein products across five GRAS-certified expression hosts at >150,000 standard metric tons of annual biomanufacturing capacity.

Product overview

Bestzyme is an enzyme and synthetic biology solutions company founded in 2013 as a subsidiary of GenScript Biotech Corporation. The company offers a comprehensive portfolio of enzyme preparations and functional proteins across four main application areas: Grain Processing (including FastLIQ, LiqFINE, HighDEX, SuperAA, AlcGEN enzyme series for starch processing and ethanol production), Food & Nutrition (including Mellia Brazzein sweet protein, BestBAKER baking enzymes, and Proline Protease for brewing), Animal Nutrition & Health (including Promax, EnerGen Supreme, HealGen Series, and single enzyme products for feed applications), and Household Care & Textile (including PuriWise laundry proteases and SuperAA Tex textile enzymes). The company's Synesis SynBio Platform serves as the core technology foundation for developing new enzyme and protein products using AI-driven innovation. Bestzyme operates five GRAS-certified expression platforms (Aspergillus niger, Aspergillus oryzae, Pichia pastoris, Bacillus subtilis, Bacillus licheniformis) and maintains automated biomanufacturing capacity exceeding 150,000 standard metric tons.

Differentiator

Problem solved

Functional benefit

Brands

• Mellia®: Zero-calorie sweet protein brand featuring Brazzein, a naturally occurring sweet protein produced through precision fermentation. Mellia® provides sugar reduction solutions for beverages, dairy, confectionery, chocolate, and other food applications.
• Synesis
• PuriWise®
• BestBAKER®
• Proline Protease PSEP-30
• Promax
• EnerGen Supreme
• HealGen
• FastLIQ®
• LiqFINE®
• HighDEX®
• SuperAA C Series
• HighDEX FE Series
• AlcGEN Series
• SuperAA Tex Series
• BE072

Products and services

• FastLIQ Series High-temperature resistant amylases produced through deep liquid fermentation for starch liquefaction in starch sugar production, with excellent tolerance up to 110°C spray temperatures. Used by industrial starch processors and biofuel producers.
• LiqFINE Series Acid-resistant amylases for starch liquefaction in starch sugar production and fermentation industries, capable of withstanding spray temperatures over 120°C. Used by starch processors and fermentation industries.
• HighDEX Series Highly efficient blended glucose amylases combining glucoamylase and pullulanase for producing glucose with DX greater than 96%. Used by starch sugar and alcohol producers.
• SuperAA C Series Enhanced amylase specifically designed for the alcohol industry, rapidly hydrolyzing starch molecules for liquefaction in corn-based ethanol production. Suitable for high-concentration corn mash fermentation. Used by bioethanol producers.
• HighDEX FE Series Glucoamylase for alcohol production that efficiently hydrolyzes starch into fermentable sugars, enhancing protein breakdown and increasing alcohol yield. Used by ethanol manufacturers.
• AlcGEN Series

Quantifiable outcome

• Over 90% residual enzyme activity maintained after 8 weeks storage at 37°C in liquid laundry detergents
• +3 more outcomes

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability1 record

Feature6 records

Partnerships

One partnership is on record.

• GenScript Biotech CorporationcoreStrategic or Co-development PartnerBestzyme is a subsidiary of GenScript Biotech Corporation, a publicly listed company on the Hong Kong Stock Exchange. Bestzyme leverages GenScript's world-leading gene synthesis capabilities and synthetic biology expertise for its Synesis platform development.

Scale indicators7 records

Recent moves12 records

Expansion highlights6 records

Direct peers

• Novonesis (formerly Novozymes): The world's largest industrial enzyme manufacturer, producing enzymes for grain processing, food, brewing, animal feed, and household care. Direct competitor to Bestzyme across essentially every application segment, with much greater global scale and incumbency.
• AB Enzymes: Specialized industrial enzyme manufacturer focused on food, beverage, and grain processing applications. Closely comparable in product scope to Bestzyme's grain processing and food nutrition enzyme lines, though without Bestzyme's synthetic biology platform emphasis.
• Amano Enzyme: Japanese specialty enzyme manufacturer producing food, beverage, and diagnostic enzymes. Comparable to Bestzyme on food-grade enzyme expertise and product breadth, though more focused on Japan and Asia-Pacific markets.
• Advanced Enzyme Technologies: Indian-headquartered enzyme manufacturer with portfolio spanning food, animal feed, and industrial enzymes. Closely comparable mid-tier player to Bestzyme in terms of product breadth and end-market coverage, particularly in animal nutrition.
• Sunson Industry Group: Chinese enzyme manufacturer producing enzymes for baking, brewing, animal feed, and textile applications. Direct China-based competitor to Bestzyme with overlapping product categories and customer base.

Broad incumbents

• DSM-Firmenich: Post-merger combined entity with a large food and beverage ingredients portfolio including industrial enzymes for baking, brewing, and animal nutrition. Competes with Bestzyme as part of a much broader ingredients, flavors, and nutrition stack.
• Kemin Industries: Global ingredient manufacturer serving animal nutrition, pet food, and food technology markets. Competes with Bestzyme's animal nutrition enzyme portfolio as part of a broader feed additives and ingredient platform.
• IFF (DuPont Nutrition & Biosciences): Large global ingredients company with an enzyme portfolio spanning food, beverage, grain processing, and animal nutrition. Competes with Bestzyme across multiple verticals within a much larger specialty ingredients portfolio.
• Cargill: Global agribusiness and food ingredient company with internal enzyme applications and partnerships across grain processing and animal nutrition. Tangential competitor and potential customer/partner to Bestzyme in industrial enzyme supply.

Regional players

• Biovet JSC: Bulgarian-based manufacturer of feed enzymes and probiotics for animal nutrition. Comparable to Bestzyme's animal nutrition product lines, but focused primarily on Eastern European and CIS markets rather than global distribution.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/@bestzyme
• LinkedInlinkedin.com/company/bestzyme
• Xx.com/bestzyme
• Facebookfacebook.com/Jinan-Bestzyme-Bio-Engineering-Co-Ltd-105626528332402

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries2 records

Funding overview

Funding rounds1 record

Investors8 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bestzyme