CDA Foundation

What CDA Foundation does

CDA Foundation is a US 501(c)(3) non-profit foundation headquartered in Lafayette, Colorado, that exists to accelerate the global elimination of viral hepatitis B and C. Its core asset is the Polaris Observatory, a WHO Collaborating Centre that provides country-level epidemiological data, disease-burden modeling, and decision-support tools to ministries of health and public health agencies in over 100 countries and territories. The platform is built on two proprietary models: the Bright HCV Model and the PRoGReSs HBV Model, both of which have been validated in more than 65 peer-reviewed publications and are updated annually with input from national collaborators. Supporting tools include Patient Registries, EPIC Searches integrated with electronic health record systems, and a suite of visualization modules (Dashboard, Compare, Elimination Maps, Global Distribution, Database Query, Migration Analyses).

The foundation's business model is grant-funded rather than commercial. The John C. Martin Foundation became the sole funder of the Polaris Observatory in 2024 ($7M grant in November 2024). Gilead Sciences funds the Relink grant program in the United States ($8M, 2023–2025) as well as the ALLIES and CAMEO grant programs, and co-funds the Tajikistan demonstration project with the Gilead Foundation. Other past funders include ZeShan Foundation, EndHep2030 Hepatitis Fund, and AbbVie. CDA Foundation also accepts individual donations directed to four pillars: Research and Modeling, Grant Programs, Free Public Tools, and Equitable Healthcare, plus an unrestricted bucket. Polaris cascade-of-care data is provided free of charge to national policymakers, decision makers, and collaborators; other non-governmental organizations pay a fee for access. Operating entities include the US parent, a Czech foundation (Nadační fond CDAF) in Prague, and a Representative Office in Tashkent, Uzbekistan, supporting the Uzbekistan Hepatitis Elimination Program.

CDA Foundation combines research and modeling with targeted grantmaking and on-the-ground demonstration projects to translate data into action. The organization runs multiple grant programs (Relink for U.S. case-finding, ALLIES for patient advocacy, CAMEO for HIV literacy, Tajikistan for Central Asia elimination), operates a Global Procurement Fund to expand access to hepatitis diagnostics and treatments, and works with an extensive global network of academic and clinical collaborators across 100+ countries.

Name

CDA Foundation

Legal name

Center for Disease Analysis Foundation

Website

https://cdafound.org

Company type

Private

Founded year

2016

Operating status

Operating

Headcount range

11–50 employees

Short description

CDA Foundation is a US 501(c)(3) non-profit that operates the WHO-designated Polaris Observatory, providing epidemiological data, proprietary disease-burden models (Bright HCV, PRoGReSs HBV), and targeted grant programs to support global elimination of viral hepatitis B and C across 100+ countries.

Ownership category

akta.pro rank

Headquarters

HQ city

Lafayette

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Others, Marketing or Sales, Infrastructure

Revenue model

1. Charitable Grants and Foundation Funding: Primary funding comes from major donors and pharmaceutical companies as restricted and unrestricted grants. John C. Martin Foundation fully funds the Polaris Observatory since 2024. Gilead Sciences provided $8M for Relink, $7M from John C. Martin Foundation for Polaris, and co-funds the Tajikistan project with the Gilead Foundation. Past funders include ZeShan Foundation, EndHep2030 Hepatitis Fund, and AbbVie. CDA Foundation has donated or committed more than $12.0 million USD to support education, country support and demonstration projects.
2. Polaris Observatory Data Access Fees: Polaris cascade of care data is provided free of charge to national policymakers, decision makers, and collaborators via the Polaris Observatory Access portal. Other (non-governmental) organizations can access the same data for a fee, with revenue used to support ongoing operation of the Polaris Observatory.
3. Individual Donations: Tax-deductible charitable donations from individuals, accepted via PayPal or pledge, directed to one of four pillars: Research & Modeling, Grant Programs, Free Public Tools, Equitable Healthcare, or Unrestricted.

Pricing tiers

Go-to-market motion4 records

Distribution channels1 record

Marketing channels8 records

Core offering

The CDA Foundation (Center for Disease Analysis Foundation) is a US 501(c)(3) nonprofit that operates the Polaris Observatory — a WHO Collaborating Centre providing epidemiological data, proprietary disease models (Bright HCV and PRoGReSs HBV), and decision analytics for hepatitis B and C elimination in 100+ countries. It translates these data-driven insights into action through grant programs (Relink, ALLIES, CAMEO), country demonstration projects (Uzbekistan, Tajikistan), and tools such as Patient Registries and EPIC Searches, funded primarily by the John C. Martin Foundation and Gilead Sciences.

Product overview

CDA Foundation (Center for Disease Analysis Foundation) is a non-profit that operates a single unified platform, the Polaris Observatory, which serves as the umbrella for a portfolio of disease-modeling and data-dissemination modules — Polaris Dashboard, Polaris Compare, Polaris Elimination Maps, Polaris Global Distribution, Polaris Database Query, Polaris Migration Analyses, and Polaris Training — all powered by the proprietary CDA Bright (HCV) and PRoGReSs (HBV) epidemiological models. Around this core platform, CDA Foundation runs a suite of complementary programs and tools that translate modeling insights into real-world elimination impact, including the Relink Grant Program, the ALLIES Program, the CAMEO Program, the Global Procurement Fund, the Tajikistan Project, and supporting tools such as Patient Registries and EPIC Searches.

Differentiator

Problem solved

Functional benefit

Brands

• Polaris Observatory: WHO Collaborating Centre for Disease Epidemiology Analytics on Viral Hepatitis and Liver Diseases. Provides epidemiological data, modeling tools, training, and decision analytics to support the global elimination of hepatitis B and C by 2030. Operates in over 100 countries/territories.
• Relink
• ALLIES
• CAMEO
• Tajikistan Project

Products and services

• Polaris Observatory Web platform providing national/regional dashboards, country comparison tools, elimination maps, global distribution maps, migration analyses, database query, and a training portal for hepatitis B and C epidemiology, modeling, and decision analytics. Hosted by CDA Foundation and designated as a WHO Collaborating Centre for Disease Epidemiology Analytics on Viral Hepatitis and Liver Diseases. Used by national policymakers, ministries of health, academic researchers, and other organizations in 100+ countries/territories.
• Patient Registry Tool Digital patient registry tool used to track the viral hepatitis cascade of care, including deployments in Uzbekistan, Uganda, and other demonstration projects. Used by ministries of health, hospitals, and demonstration-project partners to record and follow diagnosed patients through testing, treatment, and outcomes.
• EPIC Searches Tool Search tool integrated with EPIC health record systems to identify diagnosed but untreated HCV/HBV patients for re-engagement and linkage to care. Used by US healthcare institutions, public health agencies, and Relink program sub-grantees to find lost-to-follow-up patients.
• Relink Grant Program US-based grant program (2023–2025) administered by CDA Foundation with $8M in Gilead Sciences funding to re-engage diagnosed but untreated HCV- and HBV-positive individuals into care. Funds are distributed as sub-grants to eligible US healthcare institutions, hospitals, clinics, and public health agencies through formal RFP rounds (treatment-agnostic).
• ALLIES Program Grant program funding patient advocacy group initiatives that empower patients, foster education, and drive meaningful change through advocacy-led programs for HBV, HCV, HDV, and PBC. CDA Foundation plans to award up to $300,000 in funds (max $30,000 per proposal) over a 12- to 18-month project timeframe, funded by Gilead Sciences.
• CAMEO Program Grant program supporting community-based and advocacy organizations that strengthen HIV prevention and treatment literacy for women and adolescent girls through education, materials development, outreach, and community-led engagement. Gilead plans to award up to $500,000 in CAMEO funds (max $50,000 per proposal), eligible in Australia, Canada, China, France, Germany, Italy, Japan, Spain, UK, and US.
• Tajikistan Hepatitis Elimination Project Multi-phase country demonstration project in Tajikistan (Phase I in 2026, Phase II in 2027) co-funded equally by the Gilead Foundation and CDA Foundation, focused on HCV and HBV screening (including 30,000 donated rapid diagnostic tests), training of family doctors and nurses, simplification of testing/treatment protocols, and collaboration with the Ministry of Health on nationwide adult screening. The program is treatment-agnostic.
• Polaris Training Program Free 1–2 week training program delivered in-country or via webinars to ministries of health, medical professionals, and public health professionals on HBV/HCV disease burden and economic impact modeling using Polaris Observatory data and tools.

Quantifiable outcome

• 287 million people globally living with chronic HBV or HCV identified as target population for the organization's work (2024 estimate).
• +4 more outcomes

Named customers7 records

Segments5 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability4 records

Feature5 records

Partnerships

Five partnerships are on record, tiered flagship, core and minor.

• World Health Organization (WHO)flagshipStrategic or Co-development PartnerPolaris Observatory is a designated WHO Collaborating Centre for Disease Epidemiology Analytics on Viral Hepatitis and Liver Diseases. CDA Foundation's Polaris data is included as partner data for the WHO Global Report. CDA Foundation has also provided pro-bono technical support to WHO regional offices (e.g., grant to WHO in Europe to provide technical assistance to EURO region countries; travel grant for WHO WPRO).
• University of MarylandcoreImplementation/ SI/ Consulting PartnerCo-developed Russian-language training modules for general practitioners (GPs) to treat HCV in Tajikistan. Based on the Ascend study in Washington, D.C., the modules demonstrate that trained GPs and nurses can achieve sustained virologic response (SVR) rates comparable to specialists. CDA Foundation supports a train-the-trainer model to scale GP training nationwide.
• World Health Organization Europe (WHO EURO)coreImplementation/ SI/ Consulting PartnerMulti-year grants from CDA Foundation to WHO in Europe to provide technical assistance to countries in the EURO region for viral hepatitis elimination (2023 and 2025).
• World Hepatitis AllianceminorGTM or Marketing PartnerEducational grant in 2017 from CDA Foundation to the World Hepatitis Alliance to support the World Hepatitis Summit in São Paulo, Brazil.
• Academic and Research Collaborator Network (100+ universities, hospitals, and liver research centers)coreStrategic or Co-development PartnerCDA Foundation has an extensive global network of academic and clinical collaborators (visible on the Our Collaborators page) — including universities (e.g., University of Geneva, Cairo University, University of São Paulo, Yonsei University, Tel Aviv University, Monash University, Stellenbosch University), liver research centers, hospitals (Mayo Clinic, Hospital Italiano de Buenos Aires, King Saud University, Erasmus MC), and liver associations (INASL, KASL, BGASL, EASL-affiliated). These collaborators provide data, review analyses, and co-author publications across 100+ countries.

Scale indicators10 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Institute for Health Metrics and Evaluation (IHME): University of Washington-based research institute that produces the Global Burden of Disease (GBD) study — the most widely cited source of global disease epidemiology estimates. Directly comparable to CDA Foundation as a peer in country-level disease burden modeling, though IHME covers all diseases while CDA Foundation specializes in liver disease.
• Avenir Health: Non-profit developer of the Spectrum/Goals/Time suite of disease modeling tools used by global health programs including HIV, family planning, and hepatitis. Closest direct peer to CDA Foundation in building purpose-built disease models used by ministries of health and global health funders.
• Coalition for Global Hepatitis Elimination: The Task Force for Global Health initiative focused on convening hepatitis elimination stakeholders, providing data, and supporting country programs. Operates in the same viral hepatitis elimination space, sharing CDA Foundation's policy-maker and country-engagement audience.
• World Hepatitis Alliance: UK-based global patient-led NGO representing hepatitis patient groups across 100+ countries. Directly comparable as a hepatitis-focused non-profit operating internationally with WHO relationships and policy engagement focus.
• The Hepatitis Fund: Swiss-based funding entity dedicated to viral hepatitis elimination grantmaking. Overlaps with CDA Foundation's grantmaking and country-support activities, and has been a recipient of CDA Foundation matching grants.

Broad incumbents

• Clinton Health Access Initiative (CHAI): Large global health non-profit operating across HIV, hepatitis, TB, and other diseases with country-level implementation programs. Comparable in non-profit disease-elimination model and government partnership approach, though broader and better-funded than CDA Foundation.
• Foundation for Innovative New Diagnostics (FIND): Geneva-based non-profit focused on diagnostic access for diseases of poverty, including HCV. Comparable in mission (bridging data/modeling with country-level elimination impact) and WHO Collaborating Centre designation.
• Gavi, the Vaccine Alliance: Public-private global health partnership focused on vaccine access. Comparable in non-profit grantmaking and country-engagement model for global disease elimination, with strong funder relationships and policy influence.

Emerging players

• Drugs for Neglected Diseases Initiative (DNDi): Non-profit R&D organization developing treatments for neglected patients. Comparable as a non-profit applying scientific and partnership models to global disease elimination, though focused on drug development rather than epidemiology.
• Treatment Action Group (TAG): US-based non-profit focused on HIV, HCV, and TB research and policy advocacy. Comparable in non-profit advocacy and scientific publication approach to disease elimination, with overlapping patient advocacy grantmaking activity.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/CDAFound
• LinkedInlinkedin.com/company/cdafound

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Subsidiaries2 records

Funding overview

Funding rounds2 records

Investors2 records

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M&A

Investments30 records

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Frequently asked questions about CDA Foundation