Linda Crnic Institute for Down Syndrome

What Linda Crnic Institute for Down Syndrome does

Linda Crnic Institute for Down Syndrome is an academic research institute housed within the University of Colorado Anschutz Medical Campus in Aurora, Colorado. Founded in 2008 and operating with 11–50 employees, the institute conducts scientific and clinical research focused on Down syndrome, with particular emphasis on understanding co-occurring health conditions and clinical differences across populations. Its flagship initiative is the Human Trisome Project, an international research program examining clinical differences in individuals with Down syndrome, with a recently launched Latin America Network studying Latino populations across the U.S. and Latin America.

The institute does not sell commercial products. Instead, its work is funded primarily through competitive research grants, most notably from the NIH INCLUDE Project (Investigating Co-occurring Conditions Across the Lifespan to Understand Down Syndrome), a federal initiative established in 2011 that has driven a 500% increase in Down syndrome research funding, supporting nearly 500 unique awards and 15 clinical trials. A $2.7 million NIH INCLUDE Project grant awarded in 2024 funds the Latin America Network, with recruitment beginning in 2025. The institute collaborates with Colorado State University on this international study and works closely with the Global Down Syndrome Foundation, which was instrumental in establishing the NIH INCLUDE Project.

As an academic unit within a public university system governed by The Regents of the University of Colorado, the institute operates as a government/state entity rather than a commercial venture. Revenue, ownership details, and pricing structures are not publicly disclosed. Its primary "customers" in a research-participant sense are individuals with Down syndrome and their families who enroll in clinical studies, while its principal institutional funders are federal agencies and nonprofit research foundations. The institute's strategic position is anchored by its unique integration into the federal INCLUDE funding channel and its affiliation with one of the largest Down syndrome research ecosystems in the country.

Name

Linda Crnic Institute for Down Syndrome

Legal name

The Regents of the University of Colorado

Website

https://medschool.cuanschutz.edu

Company type

Private

Founded year

2011

Operating status

Operating

Headcount range

11–50 employees

Short description

The Linda Crnic Institute for Down Syndrome is an academic research center at the University of Colorado Anschutz Medical Campus that conducts clinical and translational research on Down syndrome, most notably leading the international Human Trisome Project – Latin America Network funded by the NIH INCLUDE Project.

Ownership category

akta.pro rank

Headquarters

HQ city

Aurora

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Infrastructure

Revenue model

1. Research Grant Funding: The institute operates primarily through competitive research grant funding, including NIH INCLUDE Project grants. The $2.7 million grant for the Human Trisome Project - Latin America Network represents a major funding stream supporting international clinical research collaborations.

Core offering

The Linda Crnic Institute for Down Syndrome is an academic research institute within the University of Colorado Anschutz Medical Campus that conducts scientific and clinical research on Down syndrome. The institute leads and participates in clinical trials, disease studies, and translational research programs, with the Human Trisome Project - Latin America Network serving as a flagship international initiative studying clinical differences in Latinos with Down syndrome across the U.S. and Latin America.

Product overview

The Linda Crnic Institute for Down Syndrome conducts scientific research focused on Down syndrome. The institute's primary known initiative is the Human Trisome Project - Latin America Network, an international study investigating clinical differences in individuals with Down syndrome across the Latino population in the U.S. and Latin America, supported by NIH INCLUDE Project funding. The institute operates within the University of Colorado Anschutz Medical Campus research ecosystem.

Differentiator

Problem solved

Functional benefit

Products and services

• Human Trisome Project - Latin America Network

Quantifiable outcome

• 500% increase in Down syndrome research funding through NIH INCLUDE Project since 2011
• +1 more outcomes

Segments1 record

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

Two partnerships are on record, tiered core.

• NIH INCLUDE ProjectcoreOthers · 26 November 2024The NIH INCLUDE Project (Investigating Co-occurring Conditions Across the Lifespan to Understand Down Syndome) is a federal research initiative that has increased Down syndrome research funding by 500% since 2011. The Crnic Institute receives major grant support through this project, which funds the Human Trisome Project - Latin America Network study examining clinical differences in Latinos with Down syndrome across the U.S. and Latin America, with recruitment beginning in 2025.
• Colorado State UniversitycoreStrategic or Co-development PartnerScientists at the Linda Crnic Institute for Down Syndrome collaborate with Colorado State University researchers on the Human Trisome Project - Latin America Network. This partnership combines the clinical research expertise of the Crnic Institute with Colorado State University's research capabilities to conduct international studies on Down syndrome in Latino populations across the U.S. and Latin America.

Scale indicators2 records

Recent moves5 records

Expansion highlights4 records

Direct peers

• Global Down Syndrome Foundation: The Global Down Syndrome Foundation is a closely aligned advocacy and research-funding organization that helped establish the NIH INCLUDE Project. It works directly with the Linda Crnic Institute and shares the Down syndrome research mission, making it the most directly comparable peer.
• LuMind Research Down Syndrome Foundation: LuMind funds Down syndrome cognition research and clinical trials, sharing the same disease focus and federal-grant-aligned funding model. It is a leading Down syndrome research funder and operates in the same advocacy-to-research ecosystem as the Crnic Institute.
• National Down Syndrome Society: NDSS is a major Down syndrome advocacy organization that supports research and clinical care initiatives. While more advocacy-focused than the Crnic Institute, both operate in the Down syndrome ecosystem and rely on similar funding sources.
• National Down Syndrome Congress: NDSC is a national Down syndrome advocacy and education organization with programs supporting research and clinical care, making it a thematic peer in the Down syndrome research and support ecosystem.
• Trisomy 21 Research Society (T21RS): T21RS is an international scientific society dedicated to trisomy 21 research. The Crnic Institute's Latin America Network and clinical research portfolio align directly with T21RS's mission, and the organizations share researchers and conference platforms.
• Down Syndrome Education International: DSE International supports evidence-based research and education programs for individuals with Down syndrome globally, making it a peer in the translational research and program-development space overlapping with the Crnic Institute's mission.

Regional players

• Jerome Lejeune Foundation: The Jerome Lejeune Foundation is a leading European funder of Down syndrome research and operates a clinical research center in Paris. It is a regional peer with the same disease focus but primarily European geographic scope.

Broad incumbents

• Dana-Farber Cancer Institute (Trisomy 21 oncology program): Dana-Farber runs significant Down syndrome-related leukemia and oncology research programs within a broader cancer research portfolio. It is a broad incumbent that overlaps with the Crnic Institute's disease focus but operates at a much larger scale and broader mission.
• Massachusetts General Hospital Down Syndrome Program: The MGH Down Syndrome Program is a major clinical and research program within a leading academic medical center. It operates a comparable trisomy 21 research and clinical-care model within a broader institutional portfolio, making it a relevant broad-incumbent peer.
• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD): NICHD is a major NIH funder of Down syndrome research and one of the key institutes behind the INCLUDE Project. It is a broad incumbent funder and research entity that the Crnic Institute both partners with and competes against for grant dollars.

Market position

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights6 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds1 record

Investors1 record

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M&A

Investments

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Frequently asked questions about Linda Crnic Institute for Down Syndrome