Giant Biogene
Giant Biogene is a Xi'an-headquartered, Hong Kong-listed biotech company that uses proprietary synthetic biology to manufacture recombinant collagen and rare ginsenosides for functional skincare, medical devices, and functional foods, selling across hospitals, pharmacies, e-commerce, and international markets.
- Company typePublic
- Founded2000
- HeadquartersDongcheng, China
- Headcount501–1,000
- GTM typeB2C
- OfferingHardware or Manufacturing
What Giant Biogene does
Giant Biogene Holding Co., Ltd. (西安巨子生物基因技术股份有限公司; ticker 02367.HK) is a Xi'an-headquartered, Hong Kong-listed biotechnology company founded in 2000 that designs, develops, and manufactures bioactive ingredients — principally recombinant collagen and rare ginsenosides — using a proprietary synthetic biology platform. The company operates three product lines: functional skincare (flagship brands Komfymed 可复美 and Collgene 可丽金), medical devices (Class II dressings and Class III injectables including the October 2025-approved recombinant Type I α1 collagen lyophilized fiber injection), and functional foods/special medical formula foods (Sangsin 参苷 and others under the SKIGIN 欣苷 brand). Its technology stack centers on Type I, Type III, Human-like, and Mini Peptide recombinant collagens with amino acid sequences 100% identical to human collagen, plus 100kg-scale production of five high-purity rare ginsenosides.
The company commercializes through a multi-channel distribution network spanning direct hospital sales (1,700+ public hospitals and 3,000+ private hospitals/clinics), pharmacy retail (15,000+ stores), e-commerce platforms (Tmall, JD, Xiaohongshu, NetEase Kaola), offline beauty retail (Yanli, Watsons), and growing international channels in North America, Southeast Asia, and East Asia (USA, Canada, Japan, Korea, Singapore, Malaysia, Philippines, Vietnam, Thailand). In December 2025, Giant Biogene signed a strategic partnership with Sweden's Nordberg Medical granting exclusive recombinant collagen patent rights for global commercialization outside mainland China — a shift from product exports to technology licensing and ecosystem co-building. Revenue is generated primarily through one-time product sales across consumer and B2B/medical channels; specific pricing is not publicly disclosed. Recent reported financials indicate revenue growth from 244 units in 2021 to 789 units in the most recent reporting period, with growth decelerating to approximately 4% year-over-year and net income declining modestly.
Giant Biogene firmographics
Firmographics- Name
- Giant Biogene
- Legal name
- 西安巨子生物基因技术股份有限公司
- Website
- https://xajuzi.com
- Company type
- Public
- Founded year
- 2000
- Operating status
- Operating
- Headcount range
- 501–1,000 employees
- Short description
- Giant Biogene is a Xi'an-headquartered, Hong Kong-listed biotech company that uses proprietary synthetic biology to manufacture recombinant collagen and rare ginsenosides for functional skincare, medical devices, and functional foods, selling across hospitals, pharmacies, e-commerce, and international markets.
- Ownership category
- akta.pro rank
Giant Biogene industry classification
Industry- Product category
- Recombinant Collagen Skincare and Medical Aesthetic Products
- NAICS
- Biological Product (except Diagnostic) Manufacturing (325414), Medicinal and Botanical Manufacturing (325411)
- SIC
- Biological Products, (No Disgnostic Substances) (2836), Perfumes, Cosmetics & Other Toilet Preparations (2844)
- akta.pro primary industry
- Dermocosmetics & Medical-Grade Skincare (CRABAAAF)
- akta.pro secondary industries
- Wound Healing & Skin Regeneration (advanced dressings, skin substitutes) (HLAAAGAG), Skin Substitutes & Biologic/Regenerative Wound Therapies (Matrices, Grafts) (HLAHALAE), Dermatology & Aesthetics Pharmaceuticals (HLAIAAAK), Bio-based Pharmaceuticals, Nutraceuticals & Specialty Bioactives (EUAAAIAK)
Keywords
Where Giant Biogene is headquartered
LocationHeadquarters
- HQ city
- Dongcheng
- HQ country
- China
- HQ region
- Asia
Offices2 records
Markets served
Giant Biogene business model
Business model- GTM type
- B2C
- Offering type
- Hardware or Manufacturing
- Cost components
- Operations, Marketing or Sales, Personnel, Technology or R&D, Supply Chain
Revenue model
- Functional Skincare Products: Main revenue stream from topical skincare products including masks, serums, creams containing recombinant collagen. Flagship brands include Komfymed (可复美) and Collgene (可丽金). Products sold through e-commerce, hospitals, pharmacies, and retail stores.
- Medical Devices: Class II and Class III medical devices including collagen dressings, scar repair gels, oral mucosa repair liquids, gynecological repair gels, and injectable dermal fillers. Sold primarily through hospitals and pharmacies.
- Functional Foods: Health products based on rare ginsenoside technology including Sangsin (参苷) brand functional foods and dietary supplements.
- Special Medical Formula Foods: Special medical purpose formula foods developed using rare ginsenoside and collagen technologies.
Go-to-market motion2 records
Distribution channels5 records
Marketing channels5 records
Giant Biogene product offering
Product offeringCore offering
Giant Biogene designs, develops and manufactures recombinant collagen and rare ginsenoside bioactive ingredients through proprietary synthetic biology platforms, and converts them into three product categories sold under multiple brands: (1) functional skincare (Komfymed for skin repair, Collgene for anti-aging, SKIGIN with rare ginsenosides), (2) medical devices including Class II collagen dressings and scar/mucosal repair products plus Class III injectable dermal fillers, and (3) functional foods and special medical formula foods based on rare ginsenosides.
Product overview
Giant Biogene operates as a multi-brand bioscience company offering three categories of products: functional skincare, medical devices, and functional foods/special medical formula foods. The company centers its portfolio on proprietary recombinant collagen technology and rare ginsenoside production. The main brands include: 可复美 (KOMFYMED) - professional skincare for skin problem solutions; 可丽金 (Collgene) - mid-to-high-end anti-aging skincare; and 欣苷 (SKIGIN) - comprehensive rejuvenation using rare ginsenosides. Supporting brands cover medical devices (可预, 可痕, 利妍) and functional foods (参苷). Products range from Class II medical device dressings and implants to Class III injectable aesthetic products, and from topical skincare ampoules/creams/masks to oral health supplements.
Differentiator
Problem solved
Functional benefit
Brands
- 可复美 (Comfy/KOMFYMED): Professional skincare brand focused on skin problem solutions, centered on recombinant collagen
- 可丽金 (Collgene)
- 欣苷 (SKIGIN)
- 可预
- 可痕
- 可复平
- 利妍
- 参苷
Products and services
- Komfymed Recombinant Collagen Dressing (可复美重组胶原蛋白敷料) Class II medical device recombinant collagen dressing for wound repair and skin barrier restoration, sold to hospitals, pharmacies and consumers for post-procedure care and barrier repair.
- Komfymed Human-like Collagen Repair Ampoule (可复美 Human-like 重组胶原蛋白肌御修护次抛精华) High-concentration recombinant collagen repair ampoule for intensive skin repair and protection, sold as a daily-use functional skincare product through e-commerce and offline retail.
- Komfymed Collagen Brightening Repair Essence Cream (可复美重组胶原蛋白光奕律时修护精华霜) Recombinant collagen essence cream offering brightening, repair and anti-aging benefits for functional skincare consumers.
- Collgene Lifting Anti-wrinkle Cream (可丽金重组胶原蛋白蕴活提拉紧塑抗皱精萃霜) Recombinant collagen cream targeting lifting, firming and anti-wrinkle benefits for mature skin, sold as part of the mid-to-high-end Collgene anti-aging range.
- Collgene Firming Eye Cream (可丽金重组胶原蛋白蕴活立体紧致淡纹精华眼霜) Recombinant collagen eye cream for firming, tightening and reducing fine lines around the eyes, positioned in the mid-to-high-end Collgene range.
- Collgene Lifting Face Mask (可丽金重组胶原蛋白蕴活光塑紧致驻颜面膜) Recombinant collagen face mask for lifting, firming and rejuvenating skin texture, sold through e-commerce and offline retail in the Collgene anti-aging line.
- Recombinant Type I α1 Subtype Collagen Lyophilized Fiber Injection (重组I型α1亚型胶原蛋白冻干纤维注射剂) Class III medical device injectable combining recombinant Type I α1 subtype collagen lyophilized fiber for facial dermal tissue filling, sold through hospitals, dermatology clinics and medical aesthetics institutions.
- Recombinant Collagen and Hyaluronic Acid Sodium Compound Solution for Injection (注射用重组胶原蛋白和透明质酸钠复合溶液) World's first NMPA-approved combination injectable pairing recombinant collagen with sodium hyaluronate for medical aesthetics tissue regeneration and dermal filling, distributed through hospitals and clinics.
- Shenshan Functional Food (参芷) Functional food brand offering health supplements and dietary products based on rare ginsenoside technology with liver-protective, anti-tumor, immune-modulating and anti-inflammatory benefits.
Quantifiable outcome
- Full-length recombinant collagen with 100% amino acid sequence consistency with human collagen
- +5 more outcomes
Companies that use Giant Biogene
Customer profileNamed customers2 records
Segments4 records
Ideal customer profiles3 records
Giant Biogene technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
Giant Biogene partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core and minor.
- Nordberg Medical (Sweden)coreStrategic partnership for global development and commercialization of recombinant collagen technology. Giant Biogene grants Nordberg Medical patent rights for development, production, and commercialization of recombinant collagen in all markets outside mainland China. Products will target tissue regeneration in medical aesthetics. This partnership marks Giant Biogene's key step in global strategy through technology licensing and ecosystem co-building model.
- Bangkok Dusit Medical Services Group (Thailand)minorVisit and exchange with Thai medical group during World Organization of United Cities meeting in Xi'an. Explored potential cooperation in biotechnology and healthcare industry. Giant Biogene's Komfymed brand has already entered Thailand market with presence in KKV stores.
Scale indicators8 records
Recent moves6 records
Expansion highlights5 records
Giant Biogene competitors and assessment
Company assessmentDirect peers
- Sci-Tech Innovation (爱美客 / IMEIK Technology): China's leading domestic injectable aesthetics company (hyaluronic acid-based products like Hi-Ya/嗨体, Mewind/濡白天使). Closest direct peer in injectable medical aesthetics, sharing the same physician-channel model, NMPA registration playbook, and Chinese premium aesthetics consumer.
- Proya Cosmetics: Top Chinese mass-premium skincare brand (Proya, Caitang, OR, etc.) competing in the same professional/functional skincare channels (Tmall, JD, pharmacies). Comparable as a leading Chinese listed skincare company with multi-brand portfolio pursuing science-backed positioning.
- Shanghai Jahwa (JALA Group): One of China's largest heritage personal care and skincare groups (Jahwa, Herborist, Dr. Yu,佰草集). Comparable as a multi-brand Chinese skincare company with extensive pharmacy and offline retail distribution and active in TCM/functional skincare.
- Marubi (丸美): Chinese skincare brand focused on eye care and anti-aging, listed on A-shares. Comparable target customer (Chinese female consumer seeking anti-aging/skin-rejuvenation), channel mix (e-commerce + offline), and positioning as a domestically-developed science-backed skincare player.
- Bloomage Biotechnology: China's leading hyaluronic acid biotech company (parent of skincare brands including Quadha, BM Muscle Activation). Comparable as a Chinese fermentation-based bioactive ingredient platform producing skin-health actives and consumer skincare, competing directly with Giant Biogene in the 'bio-active ingredient + consumer brand' model and increasingly in injectable aesthetics.
- Botanee Biotech (贝泰妮 / Winona): Chinese dermocosmetics leader (Winona for sensitive skin). Direct competitor in the medical-grade / dermatology-positioned skincare category, sharing pharmacy and hospital channel presence and the same dermatology-credible consumer target.
Broad incumbents
- Hugel: Korean medical aesthetics company (botulinum toxin, hyaluronic acid fillers, PDO threads). Comparable as an Asia-based aesthetics player expanding globally via licensing/distribution, similar to Giant Biogene's Nordberg Medical strategy.
- Galderma: Global dermatology and aesthetics leader (Restylane, Sculptra, Dysport). Comparable as a major injectable aesthetics and dermatology franchise against which Giant Biogene's emerging recombinant collagen injectables will compete in international markets via the Nordberg Medical partnership.
Emerging players
- Sinclair Pharma (now part of Huadong Medicine): Aesthetics-focused subsidiary of Huadong Medicine (Ellansé, MaiLi, Perfectha). Comparable as a global aesthetics portfolio expanding into regenerative/bio-stimulator categories that overlap with recombinant collagen applications.
- Evolus: US aesthetics pure-play (Jeuveau/PrabotulinumtoxinA). Comparable as a focused, science-driven aesthetics challenger competing for share with deep-pocketed incumbents in injectable categories relevant to Giant Biogene's tissue regeneration ambitions.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
Giant Biogene social profiles
Digital presenceGiant Biogene compliance and trust
Trust signalCompliance7 records
Giant Biogene financial estimates
Financial estimateRevenue estimate
Valuation estimate
Giant Biogene leadership team
Management profileNumber of profiles
Profiles9 records
Giant Biogene subsidiaries and ownership
Company hierarchySubsidiaries2 records
Giant Biogene funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Giant Biogene M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Giant Biogene
What does Giant Biogene do?
Giant Biogene designs, develops and manufactures recombinant collagen and rare ginsenoside bioactive ingredients through proprietary synthetic biology platforms, and converts them into three product categories sold under multiple brands: (1) functional skincare (Komfymed for skin repair, Collgene for anti-aging, SKIGIN with rare ginsenosides), (2) medical devices including Class II collagen dressings and scar/mucosal repair products plus Class III injectable dermal fillers, and (3) functional foods and special medical formula foods based on rare ginsenosides.
Is Giant Biogene a public or private company?
Giant Biogene is a public company. It is classified as public and is currently operating.
When was Giant Biogene founded?
Giant Biogene was founded in 2000. It employs 501 to 1,000 people.
Where is Giant Biogene based?
Giant Biogene is headquartered in Dongcheng, China, in the Asia region.
How does Giant Biogene make money?
Four revenue lines are on record. Functional Skincare Products are the primary driver. The others are medical Devices, functional Foods and special Medical Formula Foods.
Who are Giant Biogene's main competitors?
Direct peers on record are Sci-Tech Innovation (爱美客 / IMEIK Technology), Proya Cosmetics, Shanghai Jahwa (JALA Group), Marubi (丸美), Bloomage Biotechnology and Botanee Biotech (贝泰妮 / Winona). Broad incumbents are Hugel and Galderma. Emerging players are Sinclair Pharma (now part of Huadong Medicine) and Evolus.
Does Giant Biogene have an API?
No public API is recorded for Giant Biogene.
What industry is Giant Biogene in?
Giant Biogene's product category is Recombinant Collagen Skincare and Medical Aesthetic Products. Its primary akta.pro industry code is CRABAAAF, Dermocosmetics & Medical-Grade Skincare, with a secondary code of HLAAAGAG, Wound Healing & Skin Regeneration (advanced dressings, skin substitutes). Its NAICS code is 325414 and its SIC code is 2836.