Milestone Scientific
Milestone Scientific is a publicly traded medical device company that develops computer-controlled injection systems using proprietary DPS Dynamic Pressure Sensing Technology for dental professionals and interventional pain/anesthesiology physicians in hospitals, ASCs, and dental practices.
- Company typePublic
- Founded1999
- HeadquartersLivingston, United States
- Headcount51–100
- GTM typeB2B
- OfferingHardware or Manufacturing
What Milestone Scientific does
Milestone Scientific, Inc. (NYSE American: MLSS) is a publicly traded medical device company headquartered in Roseland, New Jersey that develops, patents, and commercializes computer-controlled injection technologies for the dental and medical markets. Its core technology is the proprietary DPS Dynamic Pressure Sensing platform, which provides continuous real-time pressure sensing and audible feedback during needle advancement to enable objective identification of anatomical spaces and computer-controlled, sub-pain-threshold flow rates of anesthetic solution.
The company operates two main product franchises. The dental franchise is built around the STA Single Tooth Anesthesia System (marketed under "The Wand" brand), a computer-controlled local anesthesia delivery instrument featuring a bi-rotational handpiece that cancels needle deflection and delivers anesthetic at a consistent rate below the patient's pain threshold. The medical franchise centers on the CompuFlo Epidural System and the CathCheck Verification System, which provide real-time, objective pressure-based identification of the epidural space and catheter placement verification, with peer-reviewed published data showing a 99% first-attempt success rate and a 91% reduction in composite complications during spinal cord stimulator implantation.
Milestone generates revenue primarily through hardware sales of capital instruments plus recurring revenue from single-use consumables (STA and WA handpiece boxes of 50, plus accessories). In the United States the dental segment sells through an e-commerce storefront targeting licensed professionals, while the medical segment is sold via an enterprise field sales force and sales consultant network targeting pain clinics, ambulatory surgery centers, and hospitals. International distribution is handled through country-level distributor partners. The company is pursuing CPT Category I designation for code 0777T (CompuFlo) via the February 2026 launch of the CompuFlo Advisor Program, which is intended to drive 1,000-2,000 case submissions to support broader Medicare reimbursement and accelerated commercial adoption.
Milestone Scientific firmographics
Firmographics- Name
- Milestone Scientific
- Legal name
- Milestone Scientific, Inc.
- Website
- https://milestonescientific.com
- Company type
- Public
- Founded year
- 1999
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- Milestone Scientific is a publicly traded medical device company that develops computer-controlled injection systems using proprietary DPS Dynamic Pressure Sensing Technology for dental professionals and interventional pain/anesthesiology physicians in hospitals, ASCs, and dental practices.
- Ownership category
- akta.pro rank
Milestone Scientific industry classification
Industry- Product category
- Medical Devices
- NAICS
- Surgical and Medical Instrument Manufacturing (339112), Dental Equipment and Supplies Manufacturing (339114), Surgical Appliance and Supplies Manufacturing (339113)
- SIC
- Surgical & Medical Instruments & Apparatus (3841), Dental Equipment & Supplies (3843)
- akta.pro primary industry
- Open & Minimally Invasive Surgical Instruments (Handheld, Laparoscopic, MIS) (HLAHADAA)
- akta.pro secondary industries
- Dental & Oral Care Devices (Dental Units, Handpieces, Imaging) (HLAMAFAD), Single-Use Surgical Devices & Procedure Packs (Disposable instruments, drapes, kits) (HLAHADAM)
Keywords
Where Milestone Scientific is headquartered
LocationHeadquarters
- HQ city
- Livingston
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Milestone Scientific business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Marketing or Sales, Personnel, Supply Chain, Operations, Infrastructure
Revenue model
- Medical Device Sales (CompuFlo Epidural System): Sale of CompuFlo Epidural instruments and disposables to hospitals, pain clinics, and ambulatory surgery centers. Revenue is generated from both capital equipment placement and recurring disposable utilization. Medical business revenue more than doubled year-over-year in Q1 2026.
- Dental Device Sales (STA System): Sale of STA Single Tooth Anesthesia instruments and consumable handpieces to dental professionals. One-time hardware sale of STA instrument ($3,234.60) plus recurring revenue from single-use handpiece consumables (boxes of 50 at $194.40-$239.76).
- Consumables/Disposables: Recurring revenue from single-use handpieces and accessories including STA handpieces (box of 50 at $194.40), WA handpieces (box of 50 at $239.76), power cords, foot pedals, extension hoses, and O-rings.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Pay-as-you-go | STA Single Tooth Anesthesia System Instrument |
| Unit Pricing | Pay-as-you-go | STA Handpieces (Box of 50) |
| Unit Pricing | Pay-as-you-go | WA Handpieces (Box of 50) |
| Unit Pricing | Pay-as-you-go | Accessories and Replacement Parts |
Go-to-market motion2 records
Distribution channels4 records
Marketing channels8 records
Milestone Scientific product offering
Product offeringCore offering
Milestone Scientific designs, develops, and commercializes computer-controlled drug delivery instruments and disposable consumables for medical and dental applications. The company manufactures and sells two primary franchises: the STA Single Tooth Anesthesia System (and The Wand handpieces) for dental professionals, and the CompuFlo Epidural Instrument with the CathCheck Verification System for anesthesiologists, pain management physicians, hospitals, and ambulatory surgery centers. Revenue is generated from one-time capital equipment sales plus recurring sales of single-use handpiece consumables and accessories.
Differentiator
Problem solved
Functional benefit
Products and services
- STA Single Tooth Anesthesia System Computer-controlled local anesthesia delivery system for dental professionals that provides slow, controlled flow of anesthetic at a precise and consistent rate below the patient's pain threshold. Features visual and audible feedback for correct injection location identification and a bi-rotational handpiece that rotates 180 degrees to cancel needle deflection. Sold to general dentists, periodontists, endodontists, oral surgeons, and dental specialists performing single tooth anesthesia, inferior alveolar nerve blocks, palatal injections, intraligamentary injections, and pediatric dentistry procedures.
- CompuFlo Epidural Instrument Medical instrument providing real-time objective pressure sensing for epidural space identification with a 99% first-attempt success rate. Sold to anesthesiologists, pain management physicians, and interventional pain specialists for lumbar, thoracic, and cervical epidural procedures including epidural steroid injections, spinal cord stimulator implantations, and obstetric epidurals. Associated with a 91% reduction in composite complications during SCS implantation procedures.
- CathCheck Verification System Catheter placement verification system that confirms epidural catheter position without contrast injection, leveraging the same pressure-sensing technology as the CompuFlo Epidural Instrument. Used by anesthesiologists and pain management physicians during epidural access procedures.
- STA and The Wand Single-Use Handpieces (Consumables) Single-use disposable handpieces for the STA and The Wand dental instruments, sold in boxes of 50. Available SKUs include STA-5050-305 (1/2" 30g), STA-5050-301 (1" 30g), STA-5050-2725 (1 1/4" 27g), and WA-2050 series handpieces at $194.40-$239.76 per box. Drives recurring revenue for the dental franchise.
- STA and Wand Accessories and Replacement Parts Replacement and accessory components for STA/Wand dental instruments, including Wand Plus/STA Power Cord ($65.00), Wand/STA Black Foot Pedal ($220.00), Wand/STA Extension Hose Tubing 52" ($95.00), and packs of 10 O-Rings ($20.00). Supports continuous operation of installed dental equipment.
Quantifiable outcome
- 91% reduction in odds of composite complications (CSF leak, epidural blood patch, postoperative radiculopathy) during spinal cord stimulator implantation procedures compared to conventional loss-of-resistance techniques
- +4 more outcomes
Companies that use Milestone Scientific
Customer profileNamed customers4 records
Segments3 records
Ideal customer profiles3 records
Milestone Scientific technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature5 records
Milestone Scientific partnerships and signals
Strategic signalPartnerships
Five partnerships are on record, tiered core, moderate and minor.
- University of Texas Medical BranchcoreUTMB researchers published peer-reviewed study in Operative Neurosurgery demonstrating 91% reduction in composite complications with CompuFlo-guided epidural access during SCS implantation. The partnership supports clinical validation and provides peer-reviewed evidence for commercialization.
- University of Kansas Medical CentercoreDr. Dawood Sayed serves as Professor of Anesthesiology and Pain Medicine, Division Chief, and Director of Interventional Spine Services at UDKMC. He also serves as Vice Chairman of American Society of Pain and Neuroscience and is a board member of Milestone Scientific, providing clinical and strategic guidance.
- University of MinnesotamoderateAcademic partnership for clinical validation and training support, contributing to broader clinical acceptance as additional data is generated for CompuFlo technology.
- Neuro Management SolutionsmoderateVeteran consulting firm engaged by Milestone to provide claims support, documentation guidance, and payer advocacy as part of the CompuFlo Advisor Program's 'white glove' support infrastructure.
- Hayden IRminorInvestor relations firm providing IR services including press release distribution, media inquiries, and investor communications. Contacts: James Carbonara (646-755-7412) and Brett Maas (646-536-7331).
Scale indicators10 records
Recent moves8 records
Expansion highlights6 records
Milestone Scientific competitors and assessment
Company assessmentBroad incumbents
- Becton Dickinson (BD): BD manufactures surgical instruments, injection devices, and anesthesia delivery products serving hospitals and clinics—a broad incumbent in medical devices with overlapping presence in the procedural categories where CompuFlo operates.
- Stryker: Stryker is a broad medtech incumbent serving interventional pain and surgical specialties, with adjacent product portfolios in spinal and pain management that compete for the same hospital and ASC purchasing relationships targeted by Milestone Scientific.
- Hikma Pharmaceuticals: Hikma's injectable pharmaceutical portfolio includes dental and surgical anesthetics distributed to hospitals and dental offices, positioning it as a broad incumbent in injectable anesthesia adjacent to Milestone's delivery technology.
- Medtronic: Medtronic is a major manufacturer of spinal cord stimulators and interventional pain therapies—the downstream clinical application where CompuFlo's 91% complication-reduction evidence positions it as an enabling technology in the same procedural workflow.
- Dentsply Sirona: Dentsply Sirona is the largest dental equipment and supplies manufacturer globally, providing a broad portfolio of dental technology and consumables that overlaps with Milestone Scientific's dental anesthesia and instrument offerings.
- 3M (Dental Solutions): 3M's dental solutions division supplies a wide range of dental products, materials, and equipment to dental professionals, with overlapping presence in dental practice workflows where Milestone's STA system is sold.
Direct peers
- Pajunk: Pajunk is a specialist in regional anesthesia and epidural instruments, including nerve-block needles and stimulation devices, competing directly in the interventional pain and anesthesiology markets served by Milestone Scientific.
- B. Braun: B. Braun is a leading manufacturer of epidural needles, kits, and anesthesia delivery instruments used in pain management and obstetric procedures globally—directly competing with Milestone Scientific's CompuFlo Epidural System in the same procedural category.
- Septodont: Septodont is a global leader in dental anesthetics and injection systems, including computer-controlled delivery devices, directly competing with Milestone's STA Single Tooth Anesthesia System and The Wand in dental practices worldwide.
- Smiths Medical (ICU Medical): Smiths Medical, now part of ICU Medical, supplies epidural and regional anesthesia kits including loss-of-resistance syringes—the conventional alternative to Milestone's CompuFlo pressure-sensing technology in hospital and pain clinic settings.
Market position
Strengths4 records
Weaknesses4 records
Competitive moat5 records
Key risks6 records
Key highlights6 records
Customer concentration
Milestone Scientific social profiles
Digital presenceMilestone Scientific financial estimates
Financial estimateRevenue estimate
Valuation estimate
Milestone Scientific leadership team
Management profileNumber of profiles
Profiles10 records
Milestone Scientific funding detail
Funding detailFunding overview
Funding rounds6 records
Investors2 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Milestone Scientific M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Milestone Scientific
What does Milestone Scientific do?
Milestone Scientific designs, develops, and commercializes computer-controlled drug delivery instruments and disposable consumables for medical and dental applications. The company manufactures and sells two primary franchises: the STA Single Tooth Anesthesia System (and The Wand handpieces) for dental professionals, and the CompuFlo Epidural Instrument with the CathCheck Verification System for anesthesiologists, pain management physicians, hospitals, and ambulatory surgery centers. Revenue is generated from one-time capital equipment sales plus recurring sales of single-use handpiece consumables and accessories.
Is Milestone Scientific a public or private company?
Milestone Scientific is a public company. It is classified as public and is currently operating.
When was Milestone Scientific founded?
Milestone Scientific was founded in 1999. It employs 51 to 100 people.
Where is Milestone Scientific based?
Milestone Scientific is headquartered in Livingston, United States, in the North America region.
How does Milestone Scientific make money?
Three revenue lines are on record. Medical Device Sales (CompuFlo Epidural System) is the primary driver. The others are dental Device Sales (STA System) and consumables/Disposables.
Who are Milestone Scientific's main competitors?
Broad incumbents on record are Becton Dickinson (BD), Stryker, Hikma Pharmaceuticals, Medtronic, Dentsply Sirona and 3M (Dental Solutions). Direct peers are Pajunk, B. Braun, Septodont and Smiths Medical (ICU Medical).
Does Milestone Scientific have an API?
No public API is recorded for Milestone Scientific.
What industry is Milestone Scientific in?
Milestone Scientific's product category is Medical Devices. Its primary akta.pro industry code is HLAHADAA, Open & Minimally Invasive Surgical Instruments (Handheld, Laparoscopic, MIS), with a secondary code of HLAMAFAD, Dental & Oral Care Devices (Dental Units, Handpieces, Imaging). Its NAICS code is 339112 and its SIC code is 3841.