Precision Cell Systems
Precision Cell Systems is a cell-analysis instrumentation company formed in 2025 from the merger of S2 Genomics and ORFLO and the acquisition of BennuBio, selling automated tissue dissociation (Singulator), Coulter principle cell counters (Moxi), and forthcoming 3D spheroid/organoid flow cytometry (Velocyt) to academic, biopharma, and clinical-lab customers.
- Company typePrivate
- Founded2025
- HeadquartersLivermore, United States
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What Precision Cell Systems does
Precision Cell Systems (PCS), headquartered in Livermore, California, is a privately held life-sciences instrumentation company formed in September 2025 through the simultaneous acquisition of S2 Genomics (developer of the Singulator automated tissue dissociation platform) and ORFLO (developer of the Moxi Coulter principle-based cell analyzers), followed in October 2025 by the acquisition of BennuBio (developer of the Velocyt intact spheroid/organoid flow cytometer). The company addresses sample-preparation and analysis bottlenecks for single-cell genomics, cell therapy manufacturing QC, and 3D cell culture workflows, serving an installed base of more than 700 academic, biopharma, core-lab, and clinical-lab customers.
The product portfolio centers on three hardware platforms: the Singulator family (Singulator 100/200/200+) which fully automates fresh, frozen, and FFPE tissue dissociation down to inputs as small as 2 mg or 50 µm curls using a patented minimal-loss cartridge system; the Moxi family (Z, V, GO II, Flow) which uses the Coulter impedance principle to deliver NIST-traceable cell sizing and concentration with <2% CV precision, optionally combined with 1- or 2-channel fluorescence for viability, phenotyping, and reporter assays; and the Velocyt platform (in development) for high-throughput intact spheroid and organoid analysis. Recurring revenue is generated through proprietary consumables—cartridges, cassettes, isolation bundles, and reagents—while instrument revenue is captured via multi-year, quote-based enterprise sales supported by a 3-step workflow assessment process that includes 21 CFR Part 11 compliance capture.
PCS employs a sales-led, enterprise field-sales motion complemented by a direct e-commerce storefront, a large content/resource library (171 Moxi resources, 109 Singulator resources), and a webinar series. Customers include Harvard Medical School, UCSF, Yale, UPenn School of Medicine, Janssen, and consortia such as Tabula Muris, with product performance validated by 156+ peer-reviewed publications across Nature, PNAS, Cell Stem Cell, and Science Immunology. Outputs are validated for downstream compatibility with 10x Genomics (Chromium, Xenium, Visium, MERFISH), Parse Evercode, Mission Bio Tapestri, BioSkryb ResolveDNA, and BioSpyder TempO-LINC, embedding PCS upstream in the dominant single-cell genomics workflow. Leadership comprises CEO Anup Parikh, PhD (ex-BroadOak Capital Partners, 10x Genomics, Mission Bio, Ion Torrent); COO Bruce Leisz (ex-S2 Genomics, Pacific Biosciences, Affymetrix); and CCO Terry Salyer, with operational scaling supported by a partnership with MedTech CDMO Planet Innovation.
Precision Cell Systems firmographics
Firmographics- Name
- Precision Cell Systems
- Legal name
- Precision Cell Systems, Inc.
- Website
- https://precisioncellsystems.com
- Company type
- Private
- Founded year
- 2025
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- Precision Cell Systems is a cell-analysis instrumentation company formed in 2025 from the merger of S2 Genomics and ORFLO and the acquisition of BennuBio, selling automated tissue dissociation (Singulator), Coulter principle cell counters (Moxi), and forthcoming 3D spheroid/organoid flow cytometry (Velocyt) to academic, biopharma, and clinical-lab customers.
- Ownership category
- akta.pro rank
Precision Cell Systems industry classification
Industry- Product category
- Cell Analysis Instruments
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (33451)
- SIC
- Laboratory Analytical Instruments (3826)
- akta.pro primary industry
- Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE)
- akta.pro secondary industries
- Cell Therapy Quality, Analytics & Release Testing (potency, sterility, comparability) (HLAAABAK), In Vitro Model Systems & Organoid Platforms (iPSC/organoids, microphysiological systems) (HLAAAIAJ), Cell Processing & Ancillary Materials (media, cytokines, beads, vectors, disposables) (HLAAABAH)
Keywords
Where Precision Cell Systems is headquartered
LocationHeadquarters
- HQ city
- Livermore
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Precision Cell Systems business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Operations, Technology or R&D, Personnel, Marketing or Sales, Supply Chain, Infrastructure
Revenue model
- Instrument Hardware Sales: Sale of automated cell analysis instruments including Singulator 200, Singulator 200+, Moxi Z, Moxi V, Moxi GO II, and Velocyt systems. Revenue generated through direct sales with customized quotes based on workflow requirements.
- Consumables and Reagents: Recurring revenue from specialized consumables including cell analysis cassettes (Moxi Cell Analysis Cassettes, Moxi Cell Counting Cassettes), nuclei isolation cartridges (V2 150/40 dual filter cartridges, NIC+ cartridges, FFPE Flowthrough cartridges), and tissue-specific reagents. Also includes validation check beads and viability reagents.
- Kits and Bundles: Pre-configured kit bundles including Nuclei Isolation Bundles (8, 24, 96 samples), NIC+ Isolation Bundles, FFPE Nuclei Isolation Bundles, Heart Cell Isolation Bundles, and Moxi Validation/Viability Kits for specific applications.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Multi-year contract | Singulator 200 - Automated tissue dissociation for labs with automated FFPE needs |
| One time/ perpetual license | Multi-year contract | Singulator 200+ - Enhanced platform with dual sample processing |
| One time/ perpetual license | Multi-year contract | Moxi Product Line - Coulter principle cell analyzers |
| Unit Pricing | Pay-as-you-go | Consumables and Reagent Bundles |
Go-to-market motion2 records
Distribution channels2 records
Marketing channels5 records
Precision Cell Systems product offering
Product offeringCore offering
Precision Cell Systems manufactures and sells automated cell analysis instruments and proprietary consumables for single-cell genomics workflows. The Singulator platform automates tissue dissociation and nuclei isolation from fresh, frozen, and FFPE samples, while the Moxi platform combines Coulter-principle cell counting with fluorescent flow cytometry for cell sizing, concentration, and viability measurements. Recurring revenue is generated from cassettes, cartridges, reagents, and pre-configured isolation bundles sold through an online store.
Product overview
Precision Cell Systems offers a unified platform of automated cell analysis instruments and consumables designed for single-cell genomics workflows. The core portfolio comprises the Singulator family (automated tissue dissociation for fresh, frozen, and FFPE nuclei isolation) and the Moxi family (Coulter-based cell counters with integrated flow cytometry). A newly announced product, Velocyt, targets intact spheroid and organoid analysis. The company, formed from the merger of Orflo and S2 Genomics with subsequent acquisition of BennuBio, serves 700+ customers in research, biopharma, and clinical labs. Products integrate with major single-cell sequencing platforms including 10x Genomics, Parse Biosciences, and others for downstream analysis.
Differentiator
Problem solved
Functional benefit
Products and services
- Singulator 100 Entry-level automated tissue dissociation system for nuclei isolation from fresh, frozen, and FFPE tissue samples, providing standardized single-cell sample preparation for research labs.
- Singulator 200 Automated dissociation system that processes 16 samples per hour for fresh/frozen nuclei isolations, reducing 15+ manual steps to just 2 hands-on steps and delivering consistent, high-quality nuclei preps for snRNA-seq workflows. Designed for core labs and clinical labs processing >16 samples/day.
- Singulator 200+ Advanced dual-sample processing model with automated 60-minute walk-away FFPE workflow. Supports FFPE nuclei isolations at 2 samples per run with a specialized GREEN cartridge for enzyme-free deparaffinization, automating deparaffinization, rehydration, and nuclei isolation for labs with higher throughput needs.
- Moxi Z Palm-sized, cost-effective Coulter-principle cell counting and sizing system designed for routine counting and budget-conscious labs without fluorescence capability. Provides NIST-traceable size measurement (3-34µm) and concentration with <2% CV precision.
- Moxi V Enhanced viability analysis system combining Coulter counting with 1-channel fluorescent viability for accurate nuclei counting and cell viability assessment, providing true size (3-34µm) and concentration measurements with debris-immune detection.
- Moxi GO II Premium benchtop flow cytometer combining Coulter-principle counting with 2-channel fluorescence. Supports phenotyping, reporter gene checking, CAR T analysis, apoptosis detection, and comprehensive cell health monitoring for cell therapy QC and FDA-compliant workflows.
- Singulator Consumables and Reagents Proprietary cartridges, reagents, and isolation bundles for Singulator instruments including dual filter V2 150/40 cartridges, NIC+ cartridges, FFPE Flowthrough cartridges, nuclei isolation reagents, RNase inhibitors, and tissue-specific reagents. Sold as standalone products through the online store.
- Moxi Consumables and Reagents Cell analysis cassettes (S+, M+), cell counting cassettes, validation check beads, and viability reagents (Acridine Orange/Propidium Iodide) for use with Moxi instruments. Sold as standalone products through the online store.
- Nuclei Isolation Bundles and Kits Pre-configured kit bundles including Nuclei Isolation Bundles (8, 24, and 96 samples), NIC+ Isolation Bundles, FFPE Nuclei Isolation Bundles, Heart Cell Isolation Bundles, and Moxi Validation/Viability Kits designed for specific applications and offered as standalone products through the online store.
Quantifiable outcome
- 81% reduction in hands-on time for tissue dissociation workflows
- +4 more outcomes
Companies that use Precision Cell Systems
Customer profileNamed customers5 records
Segments3 records
Ideal customer profiles3 records
Precision Cell Systems technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration8 records
Feature3 records
Precision Cell Systems partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- Planet InnovationcorePrecision Cell Systems and Planet Innovation (PI), a MedTech contract development and manufacturing organization (CDMO), formed a unique partnership that consolidates cell analysis technologies and supports them with common commercial and operational infrastructure. This partnership aims to grow the cell analysis ecosystem through shared manufacturing capabilities, quality systems, and customer support infrastructure.
Scale indicators5 records
Recent moves7 records
Expansion highlights5 records
Precision Cell Systems competitors and assessment
Company assessmentBroad incumbents
- 10x Genomics: Dominant single-cell genomics platform provider whose Chromium, Xenium, Visium, and MERFISH workflows are validated as downstream applications for PCS's Singulator and Moxi products. 10x also competes indirectly via integrated sample prep and QC capabilities within its own ecosystem.
- BD Biosciences: Major flow cytometry incumbent (FACSChorus, FACSDiscover, BD CellView Image) competing with PCS's Moxi GO II and Velocyt platforms. BD's massive installed base, service network, and reagent portfolio represent both competition and a potential strategic acquirer profile.
- Beckman Coulter Life Sciences (Danaher): Cell counting and flow cytometry incumbent (Vi-Cell, CytoFLEX, MoFlo Astrios) competing directly with Moxi for routine cell analysis and viability workflows. Part of Danaher's broader life sciences instrumentation portfolio.
- Bio-Rad Laboratories: Cell counter (TC20, TC10) and flow cytometry (ZE5, S3e) competitor serving similar academic and biopharma segments as PCS. Bio-Rad's ddPCR and Droplet Digital systems overlap with downstream single-cell applications.
Direct peers
- Miltenyi Biotec: Direct competitor in automated tissue dissociation (gentleMACS Octo Dissociator) and cell analysis (MACSQuant flow cytometers). Miltenyi serves the same biopharma and academic cell therapy QC segments as PCS's Singulator and Moxi product lines.
- Cytek Biosciences: Flow cytometry specialist (Aurora, Northern Lights) competing with Moxi GO II in cell phenotyping and multi-parameter analysis. Cytek's spectral flow cytometry is a competing approach to Moxi's Coulter-plus-fluorescence design.
- Parse Biosciences: Single-cell sequencing platform (Evercode WT, Evercode TCR) validated as a downstream application of Singulator sample preparation. Parse competes with 10x Chromium and serves overlapping academic and biopharma customers.
- Mission Bio: Single-cell multi-omics platform (Tapestri) for DNA and protein analysis at single-cell resolution, validated as compatible with Singulator sample prep. Competes in single-cell oncology and cell therapy QC workflows; also a prior employer of PCS CEO Anup Parikh.
- NanoCellect Biomedical: Microfluidic cell sorting and analysis (WOLF Cell Sorter, N1 Single Cell Dispenser) targeting similar cell therapy manufacturing QC and single-cell genomics workflows as Moxi GO II.
- On-chip Biotechnologies: On-chip flow cytometry and single-cell analysis (On-chip Sort) competing in cell analysis and sorting for life science research. Comparable benchtop form factor and target market to Moxi.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights7 records
Customer concentration
Precision Cell Systems social profiles
Digital presencePrecision Cell Systems compliance and trust
Trust signalCompliance3 records
Precision Cell Systems financial estimates
Financial estimateRevenue estimate
Valuation estimate
Precision Cell Systems leadership team
Management profileNumber of profiles
Profiles3 records
Precision Cell Systems subsidiaries and ownership
Company hierarchySubsidiaries3 records
Precision Cell Systems funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Precision Cell Systems M&A and investment
M&A and investmentM&A3 records
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Precision Cell Systems
What does Precision Cell Systems do?
Precision Cell Systems manufactures and sells automated cell analysis instruments and proprietary consumables for single-cell genomics workflows. The Singulator platform automates tissue dissociation and nuclei isolation from fresh, frozen, and FFPE samples, while the Moxi platform combines Coulter-principle cell counting with fluorescent flow cytometry for cell sizing, concentration, and viability measurements. Recurring revenue is generated from cassettes, cartridges, reagents, and pre-configured isolation bundles sold through an online store.
Is Precision Cell Systems a public or private company?
Precision Cell Systems is a private company. It is classified as unknown and is currently operating.
When was Precision Cell Systems founded?
Precision Cell Systems was founded in 2025. It employs 1 to 10 people.
Where is Precision Cell Systems based?
Precision Cell Systems is headquartered in Livermore, United States, in the North America region.
How does Precision Cell Systems make money?
Three revenue lines are on record. Instrument Hardware Sales are the primary driver. The others are consumables and Reagents and kits and Bundles.
Who are Precision Cell Systems's main competitors?
Broad incumbents on record are 10x Genomics, BD Biosciences, Beckman Coulter Life Sciences (Danaher) and Bio-Rad Laboratories. Direct peers are Miltenyi Biotec, Cytek Biosciences, Parse Biosciences, Mission Bio, NanoCellect Biomedical and On-chip Biotechnologies.
Does Precision Cell Systems have an API?
No public API is recorded for Precision Cell Systems.
What industry is Precision Cell Systems in?
Precision Cell Systems's product category is Cell Analysis Instruments. Its primary akta.pro industry code is HLAGAIAE, Microscopy, Imaging & Flow Cytometry Instruments, with a secondary code of HLAAABAK, Cell Therapy Quality, Analytics & Release Testing (potency, sterility, comparability). Its NAICS code is 334516 and its SIC code is 3826.