What Celula does

Celula (赛雷纳（中国）医疗科技有限公司) is a Chengdu-headquartered, privately held in-vitro diagnostics (IVD) company founded in 2013 that develops and sells reproductive-health and clinical diagnostics products to hospitals, prenatal diagnosis centers, andrology departments, and immunology units across China. The portfolio is organized across three pillars: a genetic testing line under the AssuriT brand covering targeted NIPT (AssuriT-A/A+), single-gene NIPD (AssuriT-MD from 7 weeks gestation), three-in-one WES/CMA/CNV-seq molecular diagnostics (AssuriT-eWES-Dx), and expanded carrier screening (AssuriT-CS); a flow cytometry instrument line branded Sparrow, paired with Nest auto-sampling and Skyline/Skyline Pro automated sample processing modules, the CeK cytokine prep system, the CeM dilutor, and the CeQ high-throughput fluorescence quantifier; and a sperm function reagent series covering DNA fragmentation, acrosome reaction, mitochondrial membrane potential, nuclear DNA integrity, leukocytes, apoptosis, ROS, and plasma membrane integrity, alongside TBNK and 12-plex cytokine detection reagents. The proprietary technical foundation is a targeted amplicon sequencing NIPT architecture that lifts target chromosome sequence proportion by over 10x and achieves 500x coverage per SNP site at 3–5x lower sequencing cost than whole-genome approaches, complemented by an LD-PCR+NGS expanded carrier screening chemistry and a miniaturized NMPA Class II-registered flow cytometer offering up to seven laser/detector configurations.

Revenue is generated through one-time hardware sales of flow cytometers, automated sample processors, and supporting instruments, plus recurring consumable revenue from registered reagent kits, distributed through direct enterprise field sales teams in Chengdu and Shanghai targeting Chinese clinical institutions. The company supplements field sales with event-driven promotion via Chinese Medical Association andrology conferences, China Eugenics Association meetings, and content marketing on its own website, with a cooperation partnership with the First Affiliated Hospital of Naval Medical University for co-developed NIPD research. Operationally, the firm runs a roughly 100-person multidisciplinary technology and marketing team from a 5,000+ sqm Chengdu R&D, production, and service base, with wholly owned sales and regional offices in Shanghai, Zhuhai, and Beijing, and a US technology office in San Diego.

Name

Celula

Legal name

赛雷纳（中国）医疗科技有限公司

Website

https://celula-china.com

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

101–250 employees

Short description

Celula is a Chengdu-based Chinese IVD company founded in 2013 that designs, manufactures, and sells reproductive-health and clinical diagnostics products — including the Sparrow miniaturized flow cytometer, NIPT and carrier-screening kits under the AssuriT brand, and sperm-function reagent kits — to hospitals, prenatal diagnosis centers, and andrology departments across China.

Ownership category

akta.pro rank

Product category

Reproductive Health Diagnostics

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413), Medical Equipment and Supplies Manufacturing (3391)

SIC

In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Genetic, Cytogenetic & Prenatal Screening IVD (HLAHAAAI)

akta.pro secondary industries

Prenatal, Newborn & Reproductive Diagnostics (NIPT, IVF/PGT, newborn screening) (HLAAALAJ), IVD Reagents, Assay Kits & Consumables (Non-instrument) (HLAHAAAM), Genetic & Prenatal Testing Laboratories (HLAFAMAH), Genetic & Genomic Testing (germline, somatic, carrier, pharmacogenomics) (HLAAALAD)

Keywords

• Reproductive health diagnostics
• Flow cytometry instruments
• Prenatal genetic testing
• Clinical IVD reagents
• Non-invasive prenatal testing

Headquarters

HQ city

Chengdu

HQ country

China

HQ region

Asia

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Supply Chain, Marketing or Sales, Operations

Revenue model

1. Flow Cytometry Instruments and Reagent Kits: Sale of Sparrow series miniaturized flow cytometers and配套试剂盒 (supporting reagent kits) for reproductive health and immunology testing. Instruments sold with matching registered reagent products forming a closed-loop detection ecosystem.
2. Molecular Diagnostics Tests (NIPT, Carrier Screening, eWES): Sale of genetic testing kits and reagents for prenatal screening, carrier screening, and molecular diagnostics including NIPT, NIPT-Plus, NIPT-eWES, AssuriT-eWES-Dx, and single-gene disease NIPD solutions.

Pricing tiers

Go-to-market motion2 records

Distribution channels1 record

Marketing channels3 records

Core offering

Celula designs, manufactures, and sells reproductive health-focused in-vitro diagnostic (IVD) products, including its proprietary Sparrow miniaturized flow cytometry platform with supporting reagent kits, and the AssuriT series of molecular diagnostic kits covering non-invasive prenatal testing (NIPT), single-gene NIPD, expanded carrier screening, and three-in-one molecular diagnostics (WES/CMA/CNV-seq). The company's integrated instrument-plus-reagent solutions are sold to hospitals and clinical laboratories across China for prenatal screening, infertility diagnosis, and reproductive immunology testing.

Product overview

Celula (赛雷纳（中国）医疗科技有限公司) is a reproductive health-focused IVD company offering a multi-product portfolio organized across three main categories: (1) Genetic Testing — including AssuriT-A/A+ NIPT, AssuriT-MD single-gene NIPD, AssuriT-eWES series (Dx three-in-one molecular diagnostics and NIPT-eWES), and AssuriT-CS carrier screening products; (2) Flow Cytometry Instruments and Reagents — including Sparrow flow cytometer (with Nest auto-loading module and Skyline/Skyline Pro automated sample processing systems, CeM dilutor), supported by TBNK and cytokine detection reagent kits; and (3) Sperm Function Detection — a full suite of flow cytometry-based sperm quality reagents covering DNA fragmentation, acrosome reaction, mitochondrial membrane potential, nuclear DNA integrity, leukocytes, apoptosis, ROS, and plasma membrane, plus combination reagent kits. The CeQ high-throughput fluorescence quantitative instrument rounds out the instrument portfolio. The company also offers the CeK automated cytokine sample preparation instrument for integration with Sparrow. All instruments and reagents are designed as an integrated ecosystem for reproductive health, prenatal screening, and clinical diagnosis across tiered medical institutions in China.

Differentiator

Problem solved

Functional benefit

Brands

• AssuriT: 品牌系列，包括AssuriT-A (NIPT)、AssuriT-A+ (NIPT Plus)、AssuriT-eWES、AssuriT-CS (携带者筛查)、AssuriT-MD (单基因病NIPD)等基因检测产品线。
• Sparrow
• CeQ
• CeK
• CeM

Products and services

• Sparrow Flow Cytometer (Sparrow流式细胞仪) A miniaturized benchtop flow cytometer for clinical diagnostics, featuring active light path adjustment technology, support for up to 7 laser/detector configurations, 30,000 particles/second detection speed, and NMPA Class II medical device registration. Designed for reproductive health and immunology applications across tiered medical institutions in China.
• Nest Automatic Loading Module (Nest自动上样模块) An automatic sample loading module designed for the Sparrow series flow cytometer, enabling batch processing of up to 45 samples per run with intelligent mixing, emergency priority queuing, dynamic sample addition, and fault auto-alarm features.
• Skyline Automated Sample Processing System (Skyline全自动样本处理系统) A fully automated sample processing platform that can serve as a companion to the Sparrow flow cytometer or operate independently. Performs sample dilution, antibody addition, mixing/incubation, and reagent addition workflows, handling up to 45 samples per run with full TBNK detection pre-processing.
• CeK Automated Cytokine Sample Preparation Instrument (CeK细胞因子全自动样本制备仪) A fully automated sample preparation device customized for cytokine detection, completing standard curve dilution, reaction system configuration, incubation, and transfer to flow cytometer. Paired with Sparrow for fully automated cytokine detection. Features high-precision pipetting (CV ≤ 5%) and compact design under 60 cm width.
• Skyline Pro Automated Sample Processing Instrument (Skyline Pro全自动样本处理仪) A modular multi-function automated sample processing platform integrating tri-axis motion control, sample mixing, temperature-controlled incubation, magnetic bead separation, thermal cycling (PCR), high-precision pipetting, and microplate transfer. Supports sample dilution, nucleic acid extraction, library construction, and DNA amplification workflows.
• CeM Dilutor (CeM稀释仪) A high-throughput dilutor compatible with 96-well and 48-well plates, offering multi-size diluent well positions. Uses high-precision syringe pump with dilution accuracy of ±0.5 μL, single dispensing volume > 100 μL, and compact design under 60 cm width. Used in DNA dilution and library dilution workflows.
• CeQ High-Throughput Fluorescence Quantitative Instrument (CeQ高通量荧光定量仪) A high-throughput fluorescence quantitative instrument for DNA sample quantification and qualitative analysis, with 96 independent detection channels, detection sensitivity of 0.05 ng/μL using PMT detector, and 96-sample detection in under 5 minutes. Used in environmental monitoring and genetic testing.
• AssuriT-A NIPT (AssuriT-A 无创DNA产前检测) Non-invasive prenatal DNA testing based on targeted amplicon sequencing technology. Requires only 10 mL of maternal peripheral blood to assess fetal risk for trisomy 21, 18, and 13 with 500x coverage depth at disease-related detection sites.
• AssuriT-A+ NIPT Plus (AssuriT-A+) Upgraded NIPT that detects trisomy 21, 18, and 13 along with other chromosomal numerical abnormalities and chromosomal microdeletions/microduplications through enhanced algorithms. Targets pathogenic CNVs (pCNVs) with detection rate of 1.6–1.7%.
• AssuriT-MD Single-Gene NIPD (AssuriT-MD 单基因病NIPD) A non-invasive prenatal diagnosis solution using high-throughput sequencing and cffDNA haplotyping analysis for accurate detection of single-gene hereditary diseases from 7 weeks gestation without invasive procedures. Covers thalassemia, Duchenne muscular dystrophy (DMD), and spinal muscular atrophy (SMA).
• AssuriT-CS Expanded Carrier Screening (AssuriT-CS 单基因病扩展性携带者筛查) Expanded carrier screening products including a 16-gene panel covering common autosomal recessive diseases such as thalassemia, hereditary deafness, phenylketonuria, and SMA, plus AssuriT-eWES-CS for comprehensive genomic risk assessment covering genetic carrier status, adult-onset diseases, dynamic repeat expansion diseases, mitochondrial diseases, infertility markers, and pharmacogenomic variants.
• AssuriT-eWES-Dx Three-in-One Molecular Diagnostic (AssuriT-eWES-Dx 三合一分子诊断) A molecular diagnostic solution integrating Whole Exome Sequencing (WES), Chromosomal Microarray Analysis (CMA), and Copy Number Variation Sequencing (CNV-seq) into a single test. Detects sequence variants (SNV/indels), structural variants (CNV), mitochondrial diseases, and uniparental disomy (UPD) for prenatal diagnosis, pediatrics, oncology, and reproductive medicine.
• AssuriT-eWES-N Comprehensive NIPT (AssuriT-eWES-N NIPT-eWES) A comprehensive NIPT solution leveraging cell-free fetal DNA for full fetal genome screening. Detects chromosomal aneuploidy, genome-wide CNVs, single-gene diseases (dominant/recessive), uniparental disomy, mitochondrial mutations, and zygosity determination.
• Sperm Function Detection Product Series (精子功能检测产品系列) A complete flow cytometry-based sperm function detection solution covering sperm DNA fragmentation, acrosome reaction, mitochondrial membrane potential, nuclear DNA integrity, leukocyte detection, apoptosis, reactive oxygen species, and plasma membrane integrity. Includes combination reagent kits for sperm DNA fragmentation + mitochondrial membrane potential and DNA fragmentation + ROS detection.
• TBNK Detection Reagent (TBNK检测试剂) A flow cytometry reagent kit for identifying percentages and absolute counts of mature lymphocyte subsets (T lymphocytes, B lymphocytes, NK cells) using fluorescently labeled antibodies targeting CD45, CD3, CD19, CD16, and CD56 surface antigens for immune status evaluation.
• Cytokine Detection Reagent (细胞因子检测试剂) A flow cytometry-based immunofluorescence reagent kit using fluorescent microspheres to quantitatively detect 12 human cytokines (TNF-α, IL-6, IL-2, IFN-γ, IL-4, IL-10, IL-8, IL-5, IL-1β, IFN-α, IL-17A, IL-12P70) in serum, plasma, or cell culture supernatant. Used in infection, autoimmune diseases, pancreatitis, unexplained fever, and ICU patients.
• Carrier & Newborn Screening Combined (携带者筛查&新生儿筛查二合一) A combined expanded carrier screening and newborn screening solution to identify individuals carrying pathogenic variants for genetic diseases, enabling couples to assess risk of passing single-gene diseases to offspring. Covers autosomal recessive and X-linked recessive inheritance patterns.

Quantifiable outcome

• Targeted NIPT increases target chromosome sequence proportion by over 10x vs whole-genome sequencing
• +4 more outcomes

Named customers2 records

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

One partnership is on record.

• 海军军医大学第一附属医院生殖医学中心 (Reproductive Medicine Center, First Affiliated Hospital of Naval Medical University)coreStrategic or Co-development Partner · 28 October 2022Celula collaborated with the Reproductive Medicine Center of the First Affiliated Hospital of Naval Medical University to co-develop non-invasive prenatal diagnosis technology for fetal hereditary colorectal cancer. Research results were published in the international journal Prenatal Diagnosis, contributing to birth defect prevention in China's fertility protection and repair efforts.

Scale indicators7 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• BGI Genomics: BGI is the dominant Chinese NIPT and genomics provider with broad reproductive health testing; highly comparable to Celula in prenatal screening and downstream IVD testing, but operates as a much larger public genomics platform with hospital labs and a wider portfolio.
• Amoy Diagnostics: Amoy Diagnostics is a Chinese oncology and genetic diagnostics company with NMPA-registered companion diagnostic and prenatal IVD kits; comparable in molecular diagnostic product development and clinical channel sales.
• KingMed Diagnostics: KingMed is one of China's largest third-party medical laboratory networks offering a broad menu of genetic, prenatal, and reproductive diagnostics; comparable to Celula as a downstream channel for NIPT/carrier screening services.
• Beckman Coulter Life Sciences: Beckman Coulter is a global leader in clinical flow cytometry instruments and reagents; comparable to Celula's Sparrow cytometer and immune cytokine/TBNK reagent portfolio, though serving a much broader global installed base.
• BD Biosciences: BD Biosciences is a global flow cytometry and clinical immunology reagent leader; directly comparable to Celula's flow cytometry instrument and reagent business, though operating globally with a much larger product portfolio.

Direct peers

• Berry Genomics: Berry Genomics is one of the leading Chinese NIPT and prenatal diagnostics developers with established NIPT, NIPT Plus, and expanded carrier screening kits; directly competes head-to-head with Celula's AssuriT line in the same hospital channels.
• Annoroad Gene Technology: Annoroad offers sequencing-based NIPT, carrier screening, and reproductive health diagnostics with hospital-channel sales across China; directly comparable to Celula's molecular diagnostic portfolio targeting OB/GYN and prenatal centers.
• DAAN Gene: DAAN Gene is a major Chinese molecular diagnostics manufacturer with NMPA-registered IVD kits across infectious disease, genetic, and prenatal testing; comparable in clinical IVD product breadth and hospital distribution model.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries4 records

Funding overview

Funding rounds2 records

Investors4 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Celula