PerioTrap Pharmaceuticals GmbH

What PerioTrap Pharmaceuticals GmbH does

PerioTrap Pharmaceuticals GmbH is a German biopharmaceutical company founded in 2018 as a spin-off from the Fraunhofer Institute for Cell Therapy and Immunology (Fraunhofer IZI), headquartered in Halle (Saale) at the Weinberg Campus technology park. The company develops a patented selective pathoblocker technology that targets the virulence mechanisms of periodontal pathogens — specifically Porphyromonas gingivalis via the small molecule S-0636 — without killing beneficial oral bacteria, thereby preserving the oral microbiome. This mechanistic approach is differentiated from conventional broad-spectrum antibacterial oral care products such as chlorhexidine, and is supported by multiple peer-reviewed publications and an endorsement from the German Society of Periodontology (DG PARO).

The company's commercial portfolio comprises two core products unified by the underlying PerioTrap® technology: a consumer-facing Mikrobiom Zahnpasta (microbiome toothpaste) priced at €14.95 per unit and sold direct-to-consumer via a Shopify e-commerce storefront, and a professional Prophylaxe Pflege-Gel (prophylaxis care gel) distributed to dental practices through Henry Schein and direct sales channels. A sonic toothbrush (Eco Vibe 3) is offered as a complementary accessory. The company serves two primary customer segments: health-conscious consumers seeking microbiome-friendly daily oral care, and dental professionals seeking adjunctive prophylaxis solutions for periodontal treatment.

PerioTrap employs a hybrid go-to-market model combining DTC e-commerce, B2B distribution via Henry Schein, and pharmacy/dental depot partnerships across Germany, Austria, and Switzerland. The company has raised approximately €5.8M cumulatively across seed (€200K, 2021), crowd-investing (€2.7M, 2025), and Pre-Series A first tranche (€2.9M, 2026) rounds. Operational team consists of fewer than 10 employees including microbiologists, pharmacists, and dentists. The microbiome toothpaste launch in 2026 achieved a complete sell-out within 12 hours of German media coverage, and the company is currently managing demand via a production waitlist while pursuing international expansion.

Name

PerioTrap Pharmaceuticals GmbH

Legal name

PerioTrap Pharmaceuticals GmbH

Website

https://periotrap.com

Company type

Private

Founded year

2018

Operating status

Operating

Headcount range

1–10 employees

Short description

PerioTrap Pharmaceuticals GmbH is a German biotech spin-off from Fraunhofer IZI that develops a patented selective pathoblocker technology targeting Porphyromonas gingivalis virulence to treat periodontitis, selling microbiome-friendly consumer toothpaste via DTC e-commerce and a professional prophylaxis gel to dental practices through Henry Schein distribution.

Ownership category

akta.pro rank

Product category

Oral Care Pharmaceuticals

NAICS

Biological Product (except Diagnostic) Manufacturing (325414), Toilet Preparation Manufacturing (325620)

SIC

Biological Products, (No Disgnostic Substances) (2836), Perfumes, Cosmetics & Other Toilet Preparations (2844)

akta.pro primary industry

Microbiome Modulating Small Molecules & Antibiotic Alternatives (HLAAAFAG)

akta.pro secondary industry

Oral Care Products (Toothpaste, Mouthwash, Dental Floss, Whitening) (CRADAMAA)

Keywords

• Oral care products
• Microbiome toothpaste
• Periodontal therapeutics
• Dental prophylaxis gel
• Pathoblocker molecules

Headquarters

HQ city

Haale

HQ country

Germany

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B and B2C

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. Consumer Oral Care Products: Direct-to-consumer sales of PerioTrap microbiome toothpaste (€14.95 per unit) through the company's Shopify e-commerce platform. Also sells sonic toothbrushes and other oral care accessories.
2. Professional Dental Products: B2B sales of Prophylaxe Pflege-Gel (prophylaxis care gel) to dental practices through Henry Schein distribution network and direct sales to dental professionals for use in clinical settings.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels8 records

Core offering

PerioTrap develops and commercializes microbiome-friendly oral care products that selectively block the virulence mechanisms of pathogenic bacteria (notably Porphyromonas gingivalis) responsible for periodontitis while preserving the healthy oral microbiome. Its commercial portfolio includes a daily-use consumer toothpaste (Mikrobiom Zahnpasta) and a professional dental prophylaxis gel (Prophylaxe Pflege-Gel), both built on its patented PerioTrap® pathoblocker technology developed over more than 10 years at Fraunhofer IZI.

Product overview

PerioTrap Pharmaceuticals GmbH offers a dual-portfolio product strategy targeting both consumers and dental professionals, unified by the company's patented PerioTrap® technology. The consumer-facing portfolio centers on the PerioTrap® Mikrobiom Zahnpasta, a daily-use microbiome-friendly toothpaste that selectively blocks periodontal pathogens (notably Porphyromonas gingivalis) without damaging beneficial oral bacteria. The professional portfolio includes the PerioTrap® Prophylaxe Pflege-Gel, a dental-prophylaxis gel for use in clinical practice, complementing the consumer toothpaste as part of a system-care approach ("Systempflege: Professionell begleitet, präventiv gedacht"). Both products are grounded in over 10 years of research from the Fraunhofer IZI spin-off and are manufactured in Germany. The company also retails a sonic toothbrush (Eco Vibe 3) as a complementary accessory.

Differentiator

Problem solved

Functional benefit

Brands

• PerioTrap®: The company's core brand for oral microbiome-friendly dental care products including toothpaste and prophylaxis care gel.

Products and services

• PerioTrap® Mikrobiom Zahnpasta (Oral Microbiome Toothpaste) A microbiome-friendly toothpaste for daily home use that selectively blocks the virulence mechanisms of periodontal pathogens such as Porphyromonas gingivalis while preserving the healthy oral microbiome. Priced at €14.95 per unit (€19.93 per 100ml), sold direct-to-consumer and through professional channels.
• PerioTrap® Prophylaxe Pflege-Gel (Prophylaxis Care Gel) A prophylaxis care gel for professional dental use that supports tissue regeneration, soothes tissue, and complements periodontal prophylaxis treatment for patients with gingival or periodontal risk. Uses the same selective PerioTrap® technology as the consumer toothpaste. Distributed via Henry Schein and direct sales to dental professionals.
• Schallzahnbürste Eco Vibe 3 Set S (Sonic Toothbrush Eco Vibe 3) A sonic toothbrush sold as a bundled accessory set alongside PerioTrap oral care products, priced at €69.98 per set, marketed as a complement to daily oral hygiene routines for consumers.

Quantifiable outcome

• Reduces harmful biofilm mass by up to 25%
• +3 more outcomes

Named customers3 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability3 records

Feature3 records

Partnerships

Four partnerships are on record, tiered core and minor.

• Fraunhofer IZIcoreStrategic or Co-development PartnerFraunhofer Institute for Cell Therapy and Immunology, from which PerioTrap spun off. The company was founded based on research conducted at Fraunhofer IZI, with founding scientists continuing research relationships.
• Henry ScheincoreChannel Partner/ Reseller/ DistributorOne of the largest dental product distributors globally, now distributing PerioTrap Prophylaxe Pflege-Gel and Mikrobiom Zahnpasta to dental practices in Germany through their established procurement and ordering systems.
• EMS Dental DeutschlandminorGTM or Marketing PartnerPartner for the GBT Summit 2026 in Berlin, where PerioTrap exhibited alongside EMS Dental to promote modern prevention-oriented concepts and innovative solutions for successful dental practice management.
• Fly Fulfillment GmbHminorImplementation/ SI/ Consulting PartnerLogistics and fulfillment service provider handling warehousing and shipping of PerioTrap products, using JTL-Fulfillment Network for operational management. Delivers via DPD and DHL.

Scale indicators8 records

Recent moves7 records

Expansion highlights5 records

Market position

Weaknesses4 records

Competitive moat3 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/@PerioTrapPharmaceuticals
• Facebookfacebook.com/PerioTrap
• LinkedInlinkedin.com/company/periotrap-pharmaceuticals-gmbh/?originalSubdomain=de
• Instagraminstagram.com/periotrap_pharmaceuticals

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Funding overview

Funding rounds3 records

Investors6 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about PerioTrap Pharmaceuticals GmbH