Rewin Bio
Rewin Bio is a Chinese enzyme engineering and pharmaceutical manufacturer using synthetic biology and metabolic engineering to produce APIs, enzyme preparations, food additives, dietary supplements, and cosmetic ingredients for B2B customers in pharmaceutical, food, health, cosmetic, and animal feed industries.
- Company typePrivate
- Founded2019
- HeadquartersJining, China
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Rewin Bio does
Shandong Rewin Biological Engineering Co., Ltd. (operating as Rewin Bio) is a Chinese enzyme engineering and pharmaceutical manufacturing company founded in 2019 as a joint venture between Wuhan Qirui Technology Development Co., Ltd. and Shandong Yinhe Biotechnology Co., Ltd. The company is based in the Economic Development Zone of Sishui County, Jining City, Shandong Province, where it is constructing approximately 5,000 square meters of GMP-compliant production workshop space and 3,000 square meters of R&D center offices and labs, with first-phase capital expenditure exceeding 80 million yuan. A US$13.57 million funding round from QR Pharmaceuticals in September 2021 supplements the parent entities' capital base.
Rewin Bio's core technology stack is built on synthetic biology, metabolic engineering, and enzyme engineering, applied to redesign the production processes of traditional synthesis and fermentation products. The company claims a proprietary, brand-new enzyme catalytic process aimed at achieving efficient, green, and sustainable manufacturing. Its commercial portfolio spans ten products: high-end antibiotic APIs (Daptomycin), liver-protecting APIs (Ademetionine 1,4-Butanedisulfonate, Ademetionine Disulfate Tosylate, L-Ornithine Hydrochloride), enzyme preparations (Proteinase K), food and feed additives (GABA, L-Theanine), dietary supplements (Reduced Glutathione, Glucosamine), and a cosmetic-grade ingredient (Hydrolyzed Sodium Hyaluronate). Manufacturing capability includes fermentation workshops, separation and purification (ceramic membrane, ultra-filtration, nano-filtration, resin columns), and downstream unit operations (spray drying, freeze drying, crystallization, dry packaging) under 2010-version Chinese GMP quality systems.
The company operates a sales-led B2B model, selling APIs and biochemical ingredients as one-time-purchase raw materials to pharmaceutical, food, health supplement, cosmetic, and animal feed manufacturers. Go-to-market is reinforced by six core research collaborations with the Chinese Academy of Sciences, Shanghai Institute of Pharmaceutical Industry, Shanghai Institute of Organic Chemistry, Wuhan University School of Pharmacy, Hubei University School of Life Sciences, and Wuhan Institute of Pharmaceuticals and Medical Devices, which support both R&D output and personnel training. A separate minor partnership with NZ Bio Pharma provides potential international distribution reach into premium health products and pet care markets. The company self-describes as "currently under construction" on its own materials, indicating that commercial-scale manufacturing is still being brought online.
Rewin Bio firmographics
Firmographics- Name
- Rewin Bio
- Legal name
- Shandong Rewin Biological Engineering Co., Ltd.
- Website
- https://rewinbio.com
- Company type
- Private
- Founded year
- 2019
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Rewin Bio is a Chinese enzyme engineering and pharmaceutical manufacturer using synthetic biology and metabolic engineering to produce APIs, enzyme preparations, food additives, dietary supplements, and cosmetic ingredients for B2B customers in pharmaceutical, food, health, cosmetic, and animal feed industries.
- Ownership category
- akta.pro rank
Rewin Bio industry classification
Industry- Product category
- Active Pharmaceutical Ingredient Manufacturing
- NAICS
- Pharmaceutical and Medicine Manufacturing (3254), Biological Product (except Diagnostic) Manufacturing (325414), Medicinal and Botanical Manufacturing (325411), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- Medicinal Chemicals & Botanical Products (2833), Biological Products, (No Disgnostic Substances) (2836)
- akta.pro primary industry
- Bio-based Pharmaceuticals, Nutraceuticals & Specialty Bioactives (EUAAAIAK)
- akta.pro secondary industries
- Recombinant Protein Therapeutics (enzymes, hormones, growth factors) (HLAAAAAB), Bio-based Food & Flavor Ingredients (Non-fuel Co-products: sweeteners, organic acids, flavors) (EUAAAIAJ), Biological Formulation, Fermentation & Scale-Up Manufacturing (AFABAEAM)
Keywords
Where Rewin Bio is headquartered
LocationHeadquarters
- HQ city
- Jining
- HQ country
- China
- HQ region
- Asia
Offices1 record
Markets served
Rewin Bio business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Operations, Technology or R&D, Personnel, Infrastructure, Supply Chain
Revenue model
- API and Pharmaceutical Sales: Manufacturing and sale of active pharmaceutical ingredients including high-end antibiotics, liver-protecting APIs, and enzyme preparations
- Food Additive Sales: Production and sale of food additives including GABA, reduced glutathione, and L-theanine
- Health Product Ingredients: Sale of health product raw materials including dietary supplements and cosmetic grade ingredients
- Enzyme Preparations: Manufacturing and sale of enzyme preparations for various industrial applications
Go-to-market motion1 record
Rewin Bio product offering
Product offeringCore offering
Rewin Bio is a Chinese biomanufacturer that develops and produces active pharmaceutical ingredients (including high-end antibiotics like Daptomycin and liver-protecting APIs such as Ademetionine salts), enzyme preparations (Proteinase K), food and feed additives (GABA, L-Theanine), dietary supplements (Reduced Glutathione, Glucosamine), and cosmetic-grade ingredients (Hydrolyzed Sodium Hyaluronate). The company uses synthetic biology, metabolic engineering, and a proprietary enzyme catalytic process to redesign conventional synthesis and fermentation routes, operating from GMP-compliant production and R&D facilities in Shandong Province, China.
Product overview
Rewin Bio is an innovative enterprise dedicated to R&D and production of high-end antibiotics, liver-protecting APIs, enzyme preparations, food additives, and health products. The company operates as a manufacturer and supplier of 10 distinct products including Active Pharmaceutical Ingredients (Ademetionine 1,4-Butanedisulfonate, Ademetionine Disulfate Tosylate, L-Ornithine Hydrochloride, Daptomycin), dietary supplements (Reduced Glutathione, Glucosamine), food/feed additives (GABA), enzyme preparations (Proteinase K), cosmetic ingredients (Hydrolyzed Sodium Hyaluronate), and amino acid supplements (L-Theanine). The portfolio spans multiple therapeutic and nutritional categories, positioning Rewin Bio as a comprehensive biological engineering company serving pharmaceutical, nutraceutical, food, feed, and cosmetic industries.
Differentiator
Problem solved
Functional benefit
Products and services
- γ-Aminobutyric Acid (GABA) GABA supplement used as a food additive, feed additive, and fertilizer additive; CAS 56-12-2, molecular weight 103.12. Sold to food, feed, and fertilizer producers requiring bio-derived GABA.
- L-Ornithine Hydrochloride Active pharmaceutical ingredient used in pharmaceutical manufacturing; CAS 3184-13-2, molecular weight 168.62. Sold to drug manufacturers as an API raw material.
- Reduced Glutathione Antioxidant supplement used as a dietary supplement and food additive; CAS 70-18-8, molecular weight 307.32. Sold to nutraceutical and food producers.
- Glucosamine Dietary supplement for joint health applications; CAS 3416-24-8, molecular weight 179.17. Sold to health supplement manufacturers.
- Ademetionine 1,4-Butanedisulfonate Liver-protecting active pharmaceutical ingredient; CAS 101020-79-5, molecular weight 833.91. Sold to pharmaceutical manufacturers producing liver-protecting drugs.
- Ademetionine Disulfate Tosylate Active pharmaceutical ingredient used in liver-protecting drug formulations; CAS 97540-22-2, molecular weight 766.79. Sold to pharmaceutical manufacturers.
- Proteinase K Enzyme preparation used as killing raw material and test reagent raw material in industrial and laboratory applications; CAS 39450-01-6, molecular weight 391.466. Sold to industrial and diagnostic reagent manufacturers.
- L-Theanine Amino acid supplement; CAS 3081-61-6, molecular weight 174.2. Sold to nutraceutical and food manufacturers as an amino acid ingredient.
- Daptomycin High-end antibiotic active pharmaceutical ingredient; CAS 103060-53-3, molecular weight 1620.67. Sold to pharmaceutical manufacturers producing high-end antibiotic drugs.
- Hydrolyzed Sodium Hyaluronate Cosmetic grade ingredient used for skin hydration in skincare formulations; CAS 9067-32-7, molecular weight less than 1000 Da. Sold to cosmetic manufacturers.
Companies that use Rewin Bio
Customer profileSegments5 records
Ideal customer profiles4 records
Rewin Bio technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature1 record
Rewin Bio partnerships and signals
Strategic signalPartnerships
Nine partnerships are on record, tiered minor and core.
- NZ Bio PharmaminorNZ Bio Pharma is a health product development and marketing company with over half a century of expertise. They focus on developing health products with premium ingredients of supreme quality for worldwide distribution. They also develop products for pet care.
- Shanghai Institute of Pharmaceutical IndustrycoreResearch and academic partnership for synthetic biology, enzyme preparations, and fermentation engineering development. R&D collaboration combined with personnel training.
- Shanghai Institute of Organic ChemistrycoreResearch and academic partnership for synthetic biology research and development collaboration.
- Chinese Academy of SciencescoreResearch and academic partnership for synthetic biology, enzyme preparations, and fermentation engineering development.
- Wuhan University School of PharmacycoreAcademic partnership for R&D in synthetic biology, enzyme preparations, and fermentation engineering, combined with personnel training.
- Hubei University School of Life SciencescoreAcademic partnership for life sciences research collaboration in synthetic biology and enzyme engineering.
- Wuhan Institute of Pharmaceuticals and Medical DevicescoreResearch institute partnership for pharmaceutical R&D and medical device development.
- Wuhan Qirui Technology Development Co., Ltd.coreJoint funder of Shandong Rewin Biological Engineering Co., Ltd. Founded in 2019 as a joint venture with Shandong Yinhe Biotechnology Co., Ltd.
- Shandong Yinhe Biotechnology Co., Ltd.coreJoint funder of Shandong Rewin Biological Engineering Co., Ltd. Founded in 2019 as a joint venture with Wuhan Qirui Technology Development Co., Ltd.
Scale indicators4 records
Recent moves6 records
Expansion highlights5 records
Rewin Bio competitors and assessment
Company assessmentDirect peers
- Fufeng Group: One of the world's largest fermentation-based amino-acid producers (MSG, lysine, threonine, valine). Comparable to Rewin's fermentation manufacturing of amino-acid products such as L-Theanine and L-Ornithine HCl.
- Meihua Bio: Leading Chinese fermentation amino-acid producer (lysine, glutamic acid, threonine, GABA) with strong scale-up expertise. Directly comparable to Rewin's food-additive and amino-acid product line, particularly GABA.
- Bloomage Biotech: Chinese fermentation-based producer of hyaluronic acid (sodium hyaluronate) for cosmetic, medical and food applications. Directly comparable because Rewin lists Hydrolyzed Sodium Hyaluronate as a core cosmetic-grade ingredient produced via fermentation.
Broad incumbents
- Zhejiang Huahai Pharmaceutical: Large Chinese API manufacturer with global regulatory filings. Comparable as a Chinese generic/innovator API producer competing in similar therapeutic categories where Rewin's high-end antibiotics and liver APIs operate.
- Amano Enzyme: Japanese specialty enzyme manufacturer serving food, pharmaceutical and diagnostic markets. Overlaps with Rewin's enzyme preparation product line and serves similar B2B ingredient customers.
- DSM-Firmenich (Taste & Bio-based): Global ingredients leader producing vitamins, nutraceuticals, enzymes and bio-based APIs through fermentation. Comparable as a broad incumbent whose bio-based ingredient portfolio spans food, pharma and personal care, mirroring Rewin's segments.
- Novozymes: Global leader in industrial enzyme preparations across pharma, food and feed. Comparable as a broad incumbent whose enzyme catalog overlaps Rewin's Proteinase K and broader enzyme engineering capability.
- Cathay Biotech: Chinese synthetic biology manufacturer of bio-based polyamides, succinic acid and bio-based chemicals via fermentation. Comparable as a large-scale Chinese bio-manufacturer using engineered strains, similar technological foundation to Rewin.
Emerging players
- Asymchem Laboratories: Chinese CDMO with fermentation and biocatalysis capabilities serving global pharma. Comparable as a fermentation-capable partner/CDMO addressing overlapping customers and process technologies.
Regional players
- Huanggang Lubao Biochemistry: Chinese fermentation-derived additive manufacturer producing L-Ornithine HCl, GABA and related amino-acid APIs. Closely overlaps Rewin's L-Ornithine HCl and GABA product lines and competes in the same domestic ingredient market.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks5 records
Key highlights7 records
Customer concentration
Rewin Bio social profiles
Digital presenceRewin Bio financial estimates
Financial estimateRevenue estimate
Valuation estimate
Rewin Bio leadership team
Management profileNumber of profiles
Rewin Bio funding detail
Funding detailFunding overview
Funding rounds1 record
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Rewin Bio M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Rewin Bio
What does Rewin Bio do?
Rewin Bio is a Chinese biomanufacturer that develops and produces active pharmaceutical ingredients (including high-end antibiotics like Daptomycin and liver-protecting APIs such as Ademetionine salts), enzyme preparations (Proteinase K), food and feed additives (GABA, L-Theanine), dietary supplements (Reduced Glutathione, Glucosamine), and cosmetic-grade ingredients (Hydrolyzed Sodium Hyaluronate). The company uses synthetic biology, metabolic engineering, and a proprietary enzyme catalytic process to redesign conventional synthesis and fermentation routes, operating from GMP-compliant production and R&D facilities in Shandong Province, China.
Is Rewin Bio a public or private company?
Rewin Bio is a private company. It is classified as venture growth investor backed and is currently operating.
When was Rewin Bio founded?
Rewin Bio was founded in 2019. It employs 11 to 50 people.
Where is Rewin Bio based?
Rewin Bio is headquartered in Jining, China, in the Asia region.
How does Rewin Bio make money?
Four revenue lines are on record. API and Pharmaceutical Sales are the primary driver. The others are food Additive Sales, health Product Ingredients and enzyme Preparations.
Who are Rewin Bio's main competitors?
Direct peers on record are Fufeng Group, Meihua Bio and Bloomage Biotech. Broad incumbents are Zhejiang Huahai Pharmaceutical, Amano Enzyme, DSM-Firmenich (Taste & Bio-based), Novozymes and Cathay Biotech. Asymchem Laboratories is listed as an emerging player. Huanggang Lubao Biochemistry is listed as a regional player.
Does Rewin Bio have an API?
No public API is recorded for Rewin Bio.
What industry is Rewin Bio in?
Rewin Bio's product category is Active Pharmaceutical Ingredient Manufacturing. Its primary akta.pro industry code is EUAAAIAK, Bio-based Pharmaceuticals, Nutraceuticals & Specialty Bioactives, with a secondary code of HLAAAAAB, Recombinant Protein Therapeutics (enzymes, hormones, growth factors). Its NAICS code is 3254 and its SIC code is 2833.