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AGTC

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uuid0004ajw

Namestring
AGTC
Legal namestring
Applied Genetic Technologies Corporation
Websiteurl
agtc.com
Company typeenum
Public
Founded yearint
1999
Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
101–250
akta.pro rankint
HeadquartersAlachua, United States
HQ citystring
Alachua
HQ countrystring
United States
HQ regionstring
North America
Markets served

Serves global market

Keyword5 values
gene therapy, ophthalmic biotechnology, AAV vectors, rare ocular diseases, clinical-stage biopharma
Industry4 codes
1AAV Vector Gene Therapy Developers
CodeHLAAACAAPrimaryYes
2Ophthalmology Gene Therapies
CodeHLAAACAGPrimaryNo
3Gene Therapy for Rare/Monogenic Diseases
CodeHLAAACAEPrimaryNo
4Rare Ophthalmology Disorder Therapies
CodeHLAIAIAKPrimaryNo
NAICS code3 codes
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
  • Biological Product (except Diagnostic) Manufacturing325414
  • Research and Development in the Physical, Engineering, and Life Sciences54171
SIC code2 codes
  • Biological Products, (No Disgnostic Substances)2836
  • Pharmaceutical Preparations2834
Product category
Ophthalmology Gene Therapy
Cost components5 values
Technology or R&D, Personnel, Operations, Infrastructure, Others
GTM typeB2B
B2B
Offering typeServices
Services
Core offering1 text field

AGTC is a clinical-stage biotechnology company developing AAV (adeno-associated virus) vector-based gene therapies for the treatment of rare and prevalent inherited ocular diseases. The company conducts human clinical trials of gene therapy candidates targeting conditions such as X-linked retinitis pigmentosa (XLRP), dry age-related macular degeneration (dAMD/GA), and cone rod dystrophy (CRD), aiming to deliver single-treatment, long-lasting therapeutic benefit.

Differentiator
Functional benefit
Problem solved
Product and service3 records
1AAV Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)
CategoryGene Therapy / Ophthalmology
Description

Investigational AAV-based gene therapy delivering a functional copy of the RPGR gene to treat patients with X-linked retinitis pigmentosa, an inherited retinal degenerative disease causing progressive vision loss.

2AAV Gene Therapy for Dry Age-related Macular Degeneration (dAMD/GA)
CategoryGene Therapy / Ophthalmology
Description

Investigational AAV gene therapy candidate designed as a single-treatment intervention for geographic atrophy associated with dry age-related macular degeneration.

3AAV Gene Therapy for Cone Rod Dystrophy (CRD)
CategoryGene Therapy / Ophthalmology
Description

Investigational AAV gene therapy targeting CDHR1-related cone rod dystrophy, an inherited retinal disease causing progressive loss of cone and rod photoreceptor function.

Scale indicator1 record

Each record includes

Type, Value, Description, Source

Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight3 records

Each record includes

Type, Description

Peers10 records
TypeEmerging player
Description

Clinical-stage genome editing company developing in vivo gene-editing therapies including EDIT-101 for Leber congenital amaurosis (LCA10), an inherited retinal disease. Comparable as a clinical-stage ocular gene-medicine company using viral vector delivery.

TypeDirect peer
Description

Clinical-stage AAV gene therapy company with a proprietary NAV technology platform developing treatments for retinal diseases (including wet AMD and rare inherited retinopathies) and other indications. Direct peer given shared AAV delivery technology and ophthalmic therapeutic focus.

TypeBroad incumbent
Description

Developer of Luxturna, the first FDA-approved AAV gene therapy for an inherited retinal disease (RPE65 mutation), making Spark the most direct commercial reference point for AGTC's ocular AAV pipeline. Acquired by Roche in 2019, Spark operates as a broad gene therapy platform player with overlapping ophthalmology focus.

TypeDirect peer
Description

Clinical-stage gene therapy company developing AAV-based treatments for ocular diseases including wet AMD and diabetic macular edema. Comparable AAV platform, ophthalmology focus, and clinical-stage development profile to AGTC.

TypeEmerging player
Description

Clinical-stage gene therapy and genome editing company with a portfolio including AAV-delivered zinc finger protein therapies for rare diseases including neurological and ocular indications. Comparable as a small-cap clinical-stage AAV gene therapy peer.

TypeDirect peer
Description

Clinical-stage gene therapy company leveraging a proprietary AAV capsid discovery platform to develop treatments for retinal diseases (including choroideremia and wet AMD) and rare diseases. Direct peer with shared AAV technology focus and ophthalmology pipeline.

TypeDirect peer
Description

Clinical-stage gene therapy company with multiple ocular programs including treatments for X-linked retinitis pigmentosa (same indication as AGTC's laru-zova) and achromatopsia. Direct competitor in AAV ocular gene therapy with parallel R&D infrastructure.

TypeDirect peer
Description

Clinical-stage gene therapy company developing AAV-based therapies for inherited retinal diseases including Leber hereditary optic neuropathy (LHON) and retinitis pigmentosa. Direct peer in ocular AAV gene therapy targeting rare inherited retinal conditions.

TypeBroad incumbent
Description

Established rare disease biopharmaceutical company developing AAV gene therapies including Roctavian for hemophilia A. Comparable as a larger rare-disease gene therapy player pursuing AAV-based modalities with regulatory and commercial scale.

TypeDirect peer
Description

Commercial-stage gene therapy company with FDA-approved Vyjuvek for dystrophic epidermolysis bullosa and a pipeline of AAV-based therapies for rare diseases. Comparable AAV platform, rare disease focus, and clinical-to-commercial transition profile.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat3 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights5 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment1 record

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles8 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds8 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors7 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment1 record

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

AGTC

Ophthalmology Gene Therapyagtc.com

AGTC firmographics

Firmographics
Name
AGTC
Legal name
Applied Genetic Technologies Corporation
Website
https://agtc.com
Company type
Public
Founded year
1999
Operating status
Operating
Headcount range
101–250 employees
Ownership category
akta.pro rank

AGTC industry classification

Industry
Product category
Ophthalmology Gene Therapy
NAICS
Research and Development in Biotechnology (except Nanobiotechnology) (541714), Biological Product (except Diagnostic) Manufacturing (325414), Research and Development in the Physical, Engineering, and Life Sciences (54171)
SIC
Biological Products, (No Disgnostic Substances) (2836), Pharmaceutical Preparations (2834)
akta.pro primary industry
AAV Vector Gene Therapy Developers (HLAAACAA)
akta.pro secondary industries
Ophthalmology Gene Therapies (HLAAACAG), Gene Therapy for Rare/Monogenic Diseases (HLAAACAE), Rare Ophthalmology Disorder Therapies (HLAIAIAK)

Keywords

  • Gene therapy
  • Ophthalmic biotechnology
  • AAV vectors
  • Rare ocular diseases
  • Clinical-stage biopharma

Where AGTC is headquartered

Location

Headquarters

HQ city
Alachua
HQ country
United States
HQ region
North America

Markets served

AGTC business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Technology or R&D, Personnel, Operations, Infrastructure, Others

AGTC product offering

Product offering

Core offering

AGTC is a clinical-stage biotechnology company developing AAV (adeno-associated virus) vector-based gene therapies for the treatment of rare and prevalent inherited ocular diseases. The company conducts human clinical trials of gene therapy candidates targeting conditions such as X-linked retinitis pigmentosa (XLRP), dry age-related macular degeneration (dAMD/GA), and cone rod dystrophy (CRD), aiming to deliver single-treatment, long-lasting therapeutic benefit.

Differentiator

Problem solved

Functional benefit

Products and services

  • AAV Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP) Investigational AAV-based gene therapy delivering a functional copy of the RPGR gene to treat patients with X-linked retinitis pigmentosa, an inherited retinal degenerative disease causing progressive vision loss.
  • AAV Gene Therapy for Dry Age-related Macular Degeneration (dAMD/GA) Investigational AAV gene therapy candidate designed as a single-treatment intervention for geographic atrophy associated with dry age-related macular degeneration.
  • AAV Gene Therapy for Cone Rod Dystrophy (CRD) Investigational AAV gene therapy targeting CDHR1-related cone rod dystrophy, an inherited retinal disease causing progressive loss of cone and rod photoreceptor function.

Companies that use AGTC

Customer profile

Segments1 record

Ideal customer profiles2 records

AGTC technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

AGTC partnerships and signals

Strategic signal

Scale indicators1 record

Recent moves6 records

Expansion highlights3 records

AGTC competitors and assessment

Company assessment

Emerging players

  • Editas Medicine: Clinical-stage genome editing company developing in vivo gene-editing therapies including EDIT-101 for Leber congenital amaurosis (LCA10), an inherited retinal disease. Comparable as a clinical-stage ocular gene-medicine company using viral vector delivery.
  • Sangamo Therapeutics: Clinical-stage gene therapy and genome editing company with a portfolio including AAV-delivered zinc finger protein therapies for rare diseases including neurological and ocular indications. Comparable as a small-cap clinical-stage AAV gene therapy peer.

Direct peers

  • REGENXBIO: Clinical-stage AAV gene therapy company with a proprietary NAV technology platform developing treatments for retinal diseases (including wet AMD and rare inherited retinopathies) and other indications. Direct peer given shared AAV delivery technology and ophthalmic therapeutic focus.
  • Adverum Biotechnologies: Clinical-stage gene therapy company developing AAV-based treatments for ocular diseases including wet AMD and diabetic macular edema. Comparable AAV platform, ophthalmology focus, and clinical-stage development profile to AGTC.
  • 4D Molecular Therapeutics: Clinical-stage gene therapy company leveraging a proprietary AAV capsid discovery platform to develop treatments for retinal diseases (including choroideremia and wet AMD) and rare diseases. Direct peer with shared AAV technology focus and ophthalmology pipeline.
  • MeiraGTx: Clinical-stage gene therapy company with multiple ocular programs including treatments for X-linked retinitis pigmentosa (same indication as AGTC's laru-zova) and achromatopsia. Direct competitor in AAV ocular gene therapy with parallel R&D infrastructure.
  • GenSight Biologics: Clinical-stage gene therapy company developing AAV-based therapies for inherited retinal diseases including Leber hereditary optic neuropathy (LHON) and retinitis pigmentosa. Direct peer in ocular AAV gene therapy targeting rare inherited retinal conditions.
  • Krystal Biotech: Commercial-stage gene therapy company with FDA-approved Vyjuvek for dystrophic epidermolysis bullosa and a pipeline of AAV-based therapies for rare diseases. Comparable AAV platform, rare disease focus, and clinical-to-commercial transition profile.

Broad incumbents

  • Spark Therapeutics: Developer of Luxturna, the first FDA-approved AAV gene therapy for an inherited retinal disease (RPE65 mutation), making Spark the most direct commercial reference point for AGTC's ocular AAV pipeline. Acquired by Roche in 2019, Spark operates as a broad gene therapy platform player with overlapping ophthalmology focus.
  • BioMarin Pharmaceutical: Established rare disease biopharmaceutical company developing AAV gene therapies including Roctavian for hemophilia A. Comparable as a larger rare-disease gene therapy player pursuing AAV-based modalities with regulatory and commercial scale.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights5 records

Customer concentration

AGTC social profiles

Digital presence

AGTC financial estimates

Financial estimate

Revenue estimate

Valuation estimate

AGTC leadership team

Management profile

Number of profiles

Profiles8 records

AGTC funding detail

Funding detail

Funding overview

Funding rounds8 records

Investors7 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

AGTC M&A and investment

M&A and investment

M&A

Investments1 record

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about AGTC

What does AGTC do?

AGTC is a clinical-stage biotechnology company developing AAV (adeno-associated virus) vector-based gene therapies for the treatment of rare and prevalent inherited ocular diseases. The company conducts human clinical trials of gene therapy candidates targeting conditions such as X-linked retinitis pigmentosa (XLRP), dry age-related macular degeneration (dAMD/GA), and cone rod dystrophy (CRD), aiming to deliver single-treatment, long-lasting therapeutic benefit.

Is AGTC a public or private company?

AGTC is a public company. It is classified as public and is currently operating.

When was AGTC founded?

AGTC was founded in 1999. It employs 101 to 250 people.

Where is AGTC based?

AGTC is headquartered in Alachua, United States, in the North America region.

Who are AGTC's main competitors?

Emerging players on record are Editas Medicine and Sangamo Therapeutics. Direct peers are REGENXBIO, Adverum Biotechnologies, 4D Molecular Therapeutics, MeiraGTx, GenSight Biologics and Krystal Biotech. Broad incumbents are Spark Therapeutics and BioMarin Pharmaceutical.

Does AGTC have an API?

No public API is recorded for AGTC.

What industry is AGTC in?

AGTC's product category is Ophthalmology Gene Therapy. Its primary akta.pro industry code is HLAAACAA, AAV Vector Gene Therapy Developers, with a secondary code of HLAAACAG, Ophthalmology Gene Therapies. Its NAICS code is 541714 and its SIC code is 2836.

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Live signals
pharmaphorumBeacon's XLRP gene therapy set for filing after phase 3 winBeacon Therapeutics plans to file for approval of its gene therapy for X-linked retinitis pigmentosa after a phase 2/3 trial showed a 31% responder rate at 12 months. The therapy, laru-zova, would be the first treatment for XLRP and the first ocular gene therapy since Luxturna in 2017.European BiotechnologyBeacon’s XLRP gene therapy meets pivotal U.S. endpointBeacon Therapeutics' gene therapy laru-zova met its U.S. pivotal endpoint in X-linked retinitis pigmentosa, with 31% and 24% of patients on higher and lower doses gaining at least 15 letters in low-luminance visual acuity versus 0% of controls. The European primary efficacy measure, retinal sensitivity, showed less clear results, and Beacon plans a U.S. biologics license application later this year.Financial TimesSyncona completes acquisition of AGTC – Company AnnouncementSyncona Limited completed the acquisition of Applied Genetic Technologies Corporation (AGTC) on November 30, 2022, investing $23.3 million upfront to take AGTC private. The deal includes contingent value rights worth up to $50 million and positions AGTC as Syncona's third retinal gene therapy portfolio company focused on advancing its lead candidate, AGTC-501, through late-stage clinical development.BioSpaceSyncona Limited Portfolio Company Successfully Completes Tender Offer and Acquisition of Applied Genetic Technologies CorporationApplied Genetic Technologies Corporation (AGTC) completed a tender offer to purchase all outstanding shares, resulting in its acquisition by a portfolio company of Syncona Limited. AGTC stockholders received $0.34 per share in cash plus potential contingent value rights, and the company is now an indirect wholly owned subsidiary of Syncona. Following the merger, AGTC's common stock was delisted from the Nasdaq Global Stock Market.GlobeNewswireSyncona Limited Portfolio Company Extends Tender Offer to Acquire Applied Genetic Technologies CorporationSyncona's portfolio company extended its tender offer to acquire Applied Genetic Technologies Corporation until Nov 30, 2022, at $0.34 per share plus up to $0.73 in contingent value rights. As of Nov 28, 30.9 million shares, about 45.1% of outstanding, had been tendered, plus 4.6 million via guaranteed delivery.GlobeNewswire*FINAL REMINDER* AGTC Urges Shareholders to Tender Their Shares by November 28, 2022 *FINAL REMINDER*Applied Genetic Technologies Corporation (AGTC) is being acquired by a Syncona Limited portfolio company in a tender offer for $0.34 per share plus up to $0.73 per share in contingent payments. The offer expires today, November 28, 2022, at 5:00 p.m. Eastern Time, and AGTC's board recommends accepting the offer.PR NewswireSHAREHOLDER ALERT: Weiss Law Reminds AGTC, OYST, VLDR, and BTRS Shareholders About Its Ongoing InvestigationsWeiss Law announced ongoing investigations into possible breaches of fiduciary duty by the boards of directors of four companies — Applied Genetic Technologies Corporation, Oyster Point Pharma, Velodyne Lidar, and BTRS Holdings — in connection with proposed acquisitions. The investigations cover four separate deals: AGTC being acquired via tender offer for $0.34 cash plus a CVR; OYST being acquired by Viatris for $11.00 cash plus a CVR worth up to $2.00 per share; VLDR merging with Ouster under a 0.8204 share exchange ratio implying $1.14 per share; and BTRS being acquired by EQT X fund for $9.50 cash per share. The law firm is seeking shareholders of these companies to contact them regarding their rights.GlobeNewswireApplied Genetic Technologies Corporation Urges Shareholders to Tender Their Shares by November 28, 2022Applied Genetic Technologies Corporation's board approved a tender offer from Syncona Limited to buy all outstanding shares at $0.34 cash plus up to $0.73 per share in contingent payments. The offer expires November 28, 2022, and the board urges shareholders to tender shares, warning that failure to do so may lead to bankruptcy.GlobeNewswireApplied Genetic Technologies Corporation Reminds Shareholders to Tender Their Shares by November 28, 2022Applied Genetic Technologies Corporation announced a tender offer from Syncona Limited to purchase all its shares, offering $0.34 per share plus up to $0.73 in milestone-based payments. The board unanimously recommends tendering, with the offer expiring November 28, 2022.PR NewswireEQUITY ALERT: The M&A Class Action Firm Announces the Investigation of Applied Genetics Technologies Corp. - AGTCMonteverde & Associates PC, a securities class action law firm, announced an investigation into the proposed acquisition of Applied Genetics Technologies Corp. (AGTC) by Syncona Limited, examining whether the deal terms are fair to AGTC shareholders.