Signature Medical Group

What Signature Medical Group does

Signature Medical Group is an independent, physician-owned multi-specialty medical group headquartered in St. Louis, Missouri, operating a network of specialty practices across the St. Louis and Kansas City metropolitan areas. Founded in 2001, the organization employs 501-1,000 staff including 60+ physicians and advanced clinicians, and delivers care across approximately 18-22 specialties and sub-specialties. Its core clinical footprint is anchored by two orthopedic practices — Signature Orthopedics St. Louis and Kansas City Bone and Joint Clinic — complemented by specialty practices in rheumatology, pediatrics, allergy and immunology, rehabilitation/spasticity, and physical therapy. The group has built its practice portfolio through a roll-up strategy, with multiple wholly-owned subsidiaries (e.g., Carondelet Rheumatology, Jefferson Pediatrics, Signature Allergy and Immunology, Signature Physical Therapy) operating as acquired-and-retained brands.

The company operates a fee-for-service healthcare delivery model, accepting most insurance plans including Medicare and Medicaid, with no public pricing. Its technology stack is limited to a conventional patient portal providing record access and bill payment, supplemented by digital marketing tools including online physician search, specialty search, and appointment request workflows; there is no proprietary AI, no mobile app, and no developer API. Go-to-market is primarily direct-to-consumer through physical clinic locations, augmented by a "Business Solutions" segment that sells employer and union health programs — including Signature Care Management, Workers' Compensation, and the Quality Care Program — to local employers and labor unions such as UFCW Local 655 and the Carpenters' Union. Signature Medical Group has been recognized as a Castle Connolly Top Doctors organization and as a 2025 Top Workplace by both the St. Louis Post-Dispatch and the Kansas City Star, and reports an average 4.75 Google star rating across its practices.

Name

Signature Medical Group

Legal name

Signature Medical Group

Website

https://signaturemedicalgroup.com

Company type

Private

Founded year

2001

Operating status

Operating

Headcount range

501–1,000 employees

Short description

Signature Medical Group is an independent, physician-owned multi-specialty medical group operating across the St. Louis and Kansas City metros, delivering care in 18-22 specialties anchored by orthopedics, rheumatology, pediatrics, allergy, rehabilitation, and physical therapy for individual patients, employers, and unions.

Ownership category

akta.pro rank

Product category

Multi-Specialty Medical Practice

NAICS

Offices of Physicians (except Mental Health Specialists) (621111)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011)

akta.pro primary industry

Value-Based Primary Care Organizations (Risk-Bearing) (HLAFAGAF)

Keywords

• Multi-specialty medical group
• Orthopedic care services
• Primary care practice
• Physical therapy services
• Physician-owned healthcare

Headquarters

HQ city

St Louis

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D, Marketing or Sales, Supply Chain

Revenue model

1. Patient Care Services: Fee-for-service healthcare delivery across multiple specialties. The group accepts most insurance plans including Medicare and Medicaid, indicating a primarily insurance-reimbursed revenue model.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels8 records

Core offering

Signature Medical Group is an independent, physician-owned multi-specialty medical group that delivers outpatient and specialty healthcare services across more than 22 specialties, including orthopedics, rheumatology, pediatrics, allergy and immunology, rehabilitation, and physical therapy. The group operates physical clinic locations in the St. Louis and Kansas City metropolitan areas and provides patient-facing services such as care management, workers' compensation support, and a patient portal for billing and records access.

Product overview

Signature Medical Group is an independent, physician-owned multi-specialty group operating a portfolio of 18 specialties/subspecialties across multiple branded practices. The core offering consists of orthopedic practices (Signature Orthopedics St. Louis, Kansas City Bone and Joint Clinic), specialty practices (Carondelet Rheumatology, Jefferson Pediatrics, Rehabilitation and Spasticity Specialists of St. Louis, Signature Allergy and Immunology, Signature Physical Therapy), patient-facing digital services (Patient Portal, Pay My Bill), and employer/unions business solutions (Signature Care Management, Workers' Compensation, Quality Care Program, Signature Speaks). The organization serves patients across St. Louis and Kansas City areas through dozens of convenient locations, many with extended hours.

Differentiator

Problem solved

Functional benefit

Brands

• Signature Orthopedics St. Louis: Orthopedic practice in St. Louis area
• Kansas City Bone and Joint Clinic
• Signature Allergy and Immunology
• Signature Physical Therapy

Products and services

• Signature Orthopedics St. Louis Orthopedic specialty care line offering diagnosis, treatment, and surgical services for musculoskeletal conditions in the St. Louis area, staffed by orthopedic physicians and surgeons.
• Kansas City Bone and Joint Clinic Orthopedic and bone-and-joint specialty care serving patients in the Kansas City metro area under the Signature Medical Group umbrella.
• Carondelet Rheumatology Rheumatology specialty service providing evaluation and treatment of autoimmune and joint-related conditions for adult patients.
• Jefferson Pediatrics Pediatric primary and specialty care service for infants, children, and adolescents offered through Signature Medical Group.
• Rehabilitation and Spasticity Specialists of St. Louis Rehabilitation and spasticity management services for patients with neuromuscular and post-injury conditions, offered in the St. Louis region.
• Signature Allergy and Immunology Allergy and immunology specialty care providing diagnosis and treatment of allergic conditions, asthma, and immune disorders.
• Signature Physical Therapy Outpatient physical therapy services supporting recovery, rehabilitation, and mobility for patients across Signature Medical Group's service lines.
• Workers' Compensation Services Workers' compensation program providing medical evaluation, treatment, and case management for injured workers and their employers/insurers.
• Signature Care Management Care management program coordinating patient care across specialties, supporting chronic disease management, transitions of care, and quality outcomes.
• Patient Portal and Online Bill Pay Online patient portal providing access to medical records, appointment scheduling, communication with providers, and bill payment functionality.

Named customers3 records

Segments2 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Partnerships

Three partnerships are on record, tiered core and minor.

• UFCW Local 655coreStrategic or Co-development PartnerUnion health and welfare partnership providing healthcare services to UFCW Local 655 members through Signature Care Management programs.
• Carpenters' UnioncoreStrategic or Co-development PartnerUnion health and welfare partnership providing healthcare services to Carpenters' Union members through Signature Care Management programs.
• Local EmployersminorStrategic or Co-development PartnerBusiness solutions partnerships with local employers to help control healthcare costs while keeping employees healthy. Includes Quality Care Program and Workers' Compensation services.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Athletico Physical Therapy: National outpatient physical therapy and orthopedic rehabilitation provider (now part of Select Medical). Comparable in delivering specialty PT and rehabilitation services that overlap with Signature Physical Therapy and orthopedic offerings.
• U.S. Physical Therapy: Public operator of outpatient physical therapy clinics across the US. Comparable in providing physical therapy services that overlap with Signature Physical Therapy and orthopedic specialty offerings.
• Esse Health: Independent, physician-owned multi-specialty group headquartered in St. Louis with primary care and specialty services. Directly comparable in geography, ownership model, and multi-specialty offering to Signature Medical Group.
• US Orthopedic Partners: PE-backed orthopedic specialty platform consolidating independent practices across multiple states. Comparable as a multi-specialty (orthopedic-anchored) group that has scaled via acquisitions, paralleling Signature's specialty practice roll-up model.
• Meritas Health: Physician-led multi-specialty group in the Kansas City metropolitan area. Directly comparable as an independent, multi-specialty provider serving one of Signature Medical Group's core geographies.

Emerging players

• Privia Health: Physician enablement company providing technology, practice management, and risk-bearing infrastructure to multi-specialty groups nationally. Comparable in supporting independent multi-specialty group models, but operates a capital-light MSO/technology model.

Broad incumbents

• One Medical (Amazon): Membership-based primary care platform (now owned by Amazon). Comparable in offering a patient-centric primary care experience with multi-specialty referrals, but operates a technology-enabled consumer model at national scale rather than an independent multi-specialty group model.
• SSM Health: Large Catholic health system serving St. Louis and the broader Midwest with hospital and physician services. Comparable in providing multi-specialty care in the same geographies, but as a broad system with inpatient services.
• BJC Medical Group: Hospital-owned physician network affiliated with BJC HealthCare in the St. Louis region. Comparable as a multi-specialty ambulatory care provider in the same geography, but operating as part of a large integrated system rather than an independent group.
• St. Luke's Health System: Major Kansas City-based health system with hospital and physician network. Comparable in providing multi-specialty ambulatory care in Signature Medical Group's Kansas City market, but as part of a broader integrated delivery system.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/signaturemedgrp
• YouTubeyoutube.com/user/SignatureMedGrp
• Facebookfacebook.com/signaturemedicalgroup
• LinkedInlinkedin.com/company/signature-medical-group
• Instagraminstagram.com/signaturemedicalgroup

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Subsidiaries7 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Signature Medical Group