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Ablynx

Full company profile

uuid0004z1j

Namestring
Ablynx
Legal namestring
Ablynx N.V.
Websiteurl
ablynx.com
Company typeenum
Private
Founded yearint
2001
Operating statusenum
Acquired
Ownership categoryenum
Headcount rangeband
251–500
akta.pro rankint
HeadquartersZwijnaarde, Belgium
HQ citystring
Zwijnaarde
HQ countrystring
Belgium
HQ regionstring
Europe
Markets served

Serves global market

Keyword5 values
nanobody therapeutics, single-domain antibodies, biopharmaceutical platform, immuno-oncology drugs, multivalent antibody fragments
Industry3 codes
1Nanobodies & Alternative Antibody Scaffolds
CodeHLAAAAAGPrimaryYes
2Bispecific & Multispecific Antibodies
CodeHLAAAAAFPrimaryNo
3Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering)
CodeHLAAAIABPrimaryNo
NAICS code3 codes
  • Biological Product (except Diagnostic) Manufacturing325414
  • Pharmaceutical Preparation Manufacturing325412
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
SIC code2 codes
  • Biological Products, (No Disgnostic Substances)2836
  • Pharmaceutical Preparations2834
Product category
Biopharmaceuticals / Nanobody Therapeutics
Social media profiles3 records
Cost components4 values
Technology or R&D, Personnel, Operations, Supply Chain
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

Ablynx developed and commercialized the proprietary NANOBODY® technology platform, a single-domain antibody fragment technology derived from heavy-chain only antibodies found in camelids (camels, llamas, alpacas) and sharks. The platform enables the engineering of multivalent nanobody molecules that can bind multiple therapeutic targets at once, supporting development of orally bioavailable treatments for immune-mediated diseases (e.g., chronic immune thrombocytopenia) and oncology, including bispecific constructs that bridge tumor cells with immune cells.

Differentiator
Functional benefit
Problem solved
Product overview1 text field

Ablynx developed the NANOBODY® Technology Platform, a proprietary platform for creating nanobody-based therapeutics. NANOBODY molecules are small protein fragments derived from heavy-chain-only antibodies found in species such as camels, llamas, alpacas, and sharks. The technology enables the creation of multivalent NANOBODY molecules that can bind to multiple targets simultaneously, allowing for complex therapeutic approaches including bridging tumor and immune cells. The platform supports oral administration of therapeutics, potentially reducing invasiveness of treatments. Ablynx N.V. holds the registered trademark for NANOBODY, and the technology is now part of Sanofi's portfolio following acquisition.

Product and service1 record
1NANOBODY® Technology Platform
CategoryBiologics / Nanobody Therapeutics Platform
Description

Proprietary platform for engineering single-domain antibody fragments (NANOBODY molecules) derived from heavy-chain only antibodies of camelids and sharks. Enables the creation of multivalent nanobody compounds that can simultaneously bind multiple targets, including bispecific constructs that bridge tumor cells and immune cells for cancer immunotherapy, with oral administration potential. Used by Ablynx (and now Sanofi) to develop therapeutics for immune-mediated diseases such as chronic immune thrombocytopenic purpura and for oncology applications.

Partnership1 partner
Strategic tierCoreTypeOEM/ Whitelabel/ Licensing Partner
Description

Sanofi acquired Ablynx and now leverages the NANOBODY® technology platform for drug discovery and development. The technology has been integrated into Sanofi's broader therapeutic development capabilities, combining NANOBODY molecules with Sanofi's large-scale manufacturing capacity to develop next-generation medicines.

Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight4 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

argenx is the closest direct peer to Ablynx, developing efgartigimod and other therapeutics based on its proprietary Fc-based antibody fragment technology derived from llama-derived single-domain antibodies (the VHH platform). Both companies pioneered single-domain antibody therapeutics and target immunology indications.

TypeDirect peer
Description

Genmab develops bispecific and multispecific antibody therapeutics using its proprietary DuoBody and HexaBody platforms. It competes with Ablynx in creating next-generation antibody-based therapeutics capable of multi-target engagement for oncology and immunology indications.

TypeBroad incumbent
Description

AstraZeneca is a large biopharma incumbent operating across oncology, immunology, and rare diseases, with significant antibody therapeutics franchises and a stated interest in nanobody-based modalities. It represents both a competitor and a potential licensing/partnering counterpart for nanobody platforms.

TypeBroad incumbent
Description

Regeneron is a leading antibody-based biopharmaceutical company with VelocImmune, VelociBi, and bispecific antibody platforms. Its therapeutic antibodies (e.g., Dupixent, Libtayo) overlap with Ablynx's immunology and oncology focus and represent large-scale commercial benchmarks.

TypeBroad incumbent
Description

Roche and its Genentech subsidiary are the world's largest developers of therapeutic monoclonal antibodies, with broad bispecific and antibody-drug conjugate programs. They compete with Ablynx's nanobody platform across the same therapeutic indications and represent the dominant commercial benchmark in biologic therapeutics.

TypeEmerging player
Description

AbCellera operates an antibody discovery platform partnering with pharma companies to identify clinical-grade antibody therapeutics, with overlapping capability in AI-driven and high-throughput antibody engineering comparable to Ablynx's discovery infrastructure.

TypeEmerging player
Description

Adimab is a technology-focused antibody discovery company that partners with biopharmaceutical firms to identify therapeutic antibodies. It shares Ablynx's platform-discovery business model but uses conventional yeast-based antibody libraries rather than camelid-derived scaffolds.

TypeEmerging player
Description

Harbour BioMed develops therapeutics using heavy-chain-only antibody (HCAb) technology derived from transgenic mice, a closely related single-domain antibody approach to Ablynx's NANOBODY platform. It targets immuno-oncology and immunology indications with a similar modality.

TypeEmerging player
Description

Ossianix is a preclinical-stage biopharma developing single-domain VNAR antibody therapeutics from sharks, directly comparable to Ablynx's use of shark-derived heavy-chain-only antibodies for therapeutic discovery.

TypeOthers
Description

Sanofi is Ablynx's strategic parent company following the 2018 acquisition, integrating the NANOBODY platform into its broader immunology, oncology, and rare disease pipeline. It is the principal commercialization and manufacturing partner for nanobody-based therapeutics originated by Ablynx.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat3 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights6 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment1 record

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature3 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles6 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds8 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors11 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Ablynx

Biopharmaceuticals / Nanobody Therapeuticsablynx.com

Ablynx firmographics

Firmographics
Name
Ablynx
Legal name
Ablynx N.V.
Website
https://ablynx.com
Company type
Private
Founded year
2001
Operating status
Acquired
Headcount range
251–500 employees
Ownership category
akta.pro rank

Ablynx industry classification

Industry
Product category
Biopharmaceuticals / Nanobody Therapeutics
NAICS
Biological Product (except Diagnostic) Manufacturing (325414), Pharmaceutical Preparation Manufacturing (325412), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
SIC
Biological Products, (No Disgnostic Substances) (2836), Pharmaceutical Preparations (2834)
akta.pro primary industry
Nanobodies & Alternative Antibody Scaffolds (HLAAAAAG)
akta.pro secondary industries
Bispecific & Multispecific Antibodies (HLAAAAAF), Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering) (HLAAAIAB)

Keywords

  • Nanobody therapeutics
  • Single-domain antibodies
  • Biopharmaceutical platform
  • Immuno-oncology drugs
  • Multivalent antibody fragments

Where Ablynx is headquartered

Location

Headquarters

HQ city
Zwijnaarde
HQ country
Belgium
HQ region
Europe

Markets served

Ablynx business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Technology or R&D, Personnel, Operations, Supply Chain

Ablynx product offering

Product offering

Core offering

Ablynx developed and commercialized the proprietary NANOBODY® technology platform, a single-domain antibody fragment technology derived from heavy-chain only antibodies found in camelids (camels, llamas, alpacas) and sharks. The platform enables the engineering of multivalent nanobody molecules that can bind multiple therapeutic targets at once, supporting development of orally bioavailable treatments for immune-mediated diseases (e.g., chronic immune thrombocytopenia) and oncology, including bispecific constructs that bridge tumor cells with immune cells.

Product overview

Ablynx developed the NANOBODY® Technology Platform, a proprietary platform for creating nanobody-based therapeutics. NANOBODY molecules are small protein fragments derived from heavy-chain-only antibodies found in species such as camels, llamas, alpacas, and sharks. The technology enables the creation of multivalent NANOBODY molecules that can bind to multiple targets simultaneously, allowing for complex therapeutic approaches including bridging tumor and immune cells. The platform supports oral administration of therapeutics, potentially reducing invasiveness of treatments. Ablynx N.V. holds the registered trademark for NANOBODY, and the technology is now part of Sanofi's portfolio following acquisition.

Differentiator

Problem solved

Functional benefit

Products and services

  • NANOBODY® Technology Platform Proprietary platform for engineering single-domain antibody fragments (NANOBODY molecules) derived from heavy-chain only antibodies of camelids and sharks. Enables the creation of multivalent nanobody compounds that can simultaneously bind multiple targets, including bispecific constructs that bridge tumor cells and immune cells for cancer immunotherapy, with oral administration potential. Used by Ablynx (and now Sanofi) to develop therapeutics for immune-mediated diseases such as chronic immune thrombocytopenic purpura and for oncology applications.

Companies that use Ablynx

Customer profile

Segments1 record

Ideal customer profiles2 records

Ablynx technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature3 records

Ablynx partnerships and signals

Strategic signal

Partnerships

One partnership is on record.

  • SanoficoreOEM/ Whitelabel/ Licensing PartnerSanofi acquired Ablynx and now leverages the NANOBODY® technology platform for drug discovery and development. The technology has been integrated into Sanofi's broader therapeutic development capabilities, combining NANOBODY molecules with Sanofi's large-scale manufacturing capacity to develop next-generation medicines.

Recent moves6 records

Expansion highlights4 records

Ablynx competitors and assessment

Company assessment

Direct peers

  • argenx: argenx is the closest direct peer to Ablynx, developing efgartigimod and other therapeutics based on its proprietary Fc-based antibody fragment technology derived from llama-derived single-domain antibodies (the VHH platform). Both companies pioneered single-domain antibody therapeutics and target immunology indications.
  • Genmab: Genmab develops bispecific and multispecific antibody therapeutics using its proprietary DuoBody and HexaBody platforms. It competes with Ablynx in creating next-generation antibody-based therapeutics capable of multi-target engagement for oncology and immunology indications.

Broad incumbents

  • AstraZeneca: AstraZeneca is a large biopharma incumbent operating across oncology, immunology, and rare diseases, with significant antibody therapeutics franchises and a stated interest in nanobody-based modalities. It represents both a competitor and a potential licensing/partnering counterpart for nanobody platforms.
  • Regeneron: Regeneron is a leading antibody-based biopharmaceutical company with VelocImmune, VelociBi, and bispecific antibody platforms. Its therapeutic antibodies (e.g., Dupixent, Libtayo) overlap with Ablynx's immunology and oncology focus and represent large-scale commercial benchmarks.
  • Roche / Genentech: Roche and its Genentech subsidiary are the world's largest developers of therapeutic monoclonal antibodies, with broad bispecific and antibody-drug conjugate programs. They compete with Ablynx's nanobody platform across the same therapeutic indications and represent the dominant commercial benchmark in biologic therapeutics.

Emerging players

  • AbCellera Biologics: AbCellera operates an antibody discovery platform partnering with pharma companies to identify clinical-grade antibody therapeutics, with overlapping capability in AI-driven and high-throughput antibody engineering comparable to Ablynx's discovery infrastructure.
  • Adimab: Adimab is a technology-focused antibody discovery company that partners with biopharmaceutical firms to identify therapeutic antibodies. It shares Ablynx's platform-discovery business model but uses conventional yeast-based antibody libraries rather than camelid-derived scaffolds.
  • Harbour BioMed: Harbour BioMed develops therapeutics using heavy-chain-only antibody (HCAb) technology derived from transgenic mice, a closely related single-domain antibody approach to Ablynx's NANOBODY platform. It targets immuno-oncology and immunology indications with a similar modality.
  • Ossianix: Ossianix is a preclinical-stage biopharma developing single-domain VNAR antibody therapeutics from sharks, directly comparable to Ablynx's use of shark-derived heavy-chain-only antibodies for therapeutic discovery.

Others

  • Sanofi (parent): Sanofi is Ablynx's strategic parent company following the 2018 acquisition, integrating the NANOBODY platform into its broader immunology, oncology, and rare disease pipeline. It is the principal commercialization and manufacturing partner for nanobody-based therapeutics originated by Ablynx.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights6 records

Customer concentration

Ablynx social profiles

Digital presence

Ablynx financial estimates

Financial estimate

Revenue estimate

Valuation estimate

Ablynx leadership team

Management profile

Number of profiles

Profiles6 records

Ablynx funding detail

Funding detail

Funding overview

Funding rounds8 records

Investors11 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

Ablynx M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Ablynx

What does Ablynx do?

Ablynx developed and commercialized the proprietary NANOBODY® technology platform, a single-domain antibody fragment technology derived from heavy-chain only antibodies found in camelids (camels, llamas, alpacas) and sharks. The platform enables the engineering of multivalent nanobody molecules that can bind multiple therapeutic targets at once, supporting development of orally bioavailable treatments for immune-mediated diseases (e.g., chronic immune thrombocytopenia) and oncology, including bispecific constructs that bridge tumor cells with immune cells.

Is Ablynx a public or private company?

Ablynx is a private company. It is classified as corporate owned and is currently acquired.

When was Ablynx founded?

Ablynx was founded in 2001. It employs 251 to 500 people.

Where is Ablynx based?

Ablynx is headquartered in Zwijnaarde, Belgium, in the Europe region.

Who are Ablynx's main competitors?

Direct peers on record are argenx and Genmab. Broad incumbents are AstraZeneca, Regeneron and Roche / Genentech. Emerging players are AbCellera Biologics, Adimab, Harbour BioMed and Ossianix. Sanofi (parent) is listed as an others.

Does Ablynx have an API?

No public API is recorded for Ablynx.

What industry is Ablynx in?

Ablynx's product category is Biopharmaceuticals / Nanobody Therapeutics. Its primary akta.pro industry code is HLAAAAAG, Nanobodies & Alternative Antibody Scaffolds, with a secondary code of HLAAAAAF, Bispecific & Multispecific Antibodies. Its NAICS code is 325414 and its SIC code is 2836.

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Live signals
European BiotechnologyCan Sanofi buy its way into in vivo CAR-T?Sanofi published preclinical data showing its in vivo CAR-T platform can deliver mRNA-encoded CARs to CD8+ T cells, generating functional CAR-T cells that inhibit tumor growth. The platform combines mRNA payloads, lipid nanoparticles, and targeted guidance from acquired companies, though CAR expression remains transient. The results are confined to hematological models, with broader applications pending.EIN PresswireNanomedicine Market Advances Rapidly with Expanding Size, Share, Innovation-Driven Trends and a Strong Forecast to 2032Maximize Market Research published a market report estimating the global Nanomedicine Market at USD 207.91 billion in 2025, projecting growth to USD 462.50 billion by 2032 at a CAGR of 12.1%, driven by advances in precision nanoparticle drug delivery, nano-enabled diagnostics, and regenerative medical devices. Specific corporate developments cited include Elan Corporation advancing a flexible nano-drug delivery patch via joint venture (May 14, 2025), Ablynx securing a €2.1 million grant for eye disease Nanobodies (December 3, 2025), and BIND Therapeutics progressing its Medicinal Nanoengineering platform through Accurin collaborations (March 18, 2025). North America leads the market with a 43.78% share, while Asia Pacific, led by China and Japan, is emerging as a growth hub supported by government nanotechnology initiatives.EIN PresswireNanomedicine Market Advances Rapidly with Expanding Size, Share, Innovation-Driven Trends and a Strong Forecast to 2032The global nanomedicine market is valued at USD 207.91 billion in 2025 and projected to reach USD 462.50 billion by 2032, growing at a CAGR of 12.1%, driven by advances in precision nanoparticle drug delivery, nano-enabled diagnostics, and regenerative medical devices. Three companies made specific reported developments: Elan Corporation advanced flexible nano-drug delivery patch technology via a joint venture, Ablynx secured a €2.1M grant for eye disease Nanobodies, and BIND Therapeutics progressed its Medicinal Nanoengineering platform through Accurin collaborations. Growth is constrained by high manufacturing costs, complex regulatory processes, and talent shortages, while North America dominates the market with a 43.78% share and Asia Pacific emerges as a key innovation hub.startupticker.chA newly launched biotech start-up with impressive study results in The LancetMoonLake Immunotherapeutics published impressive Phase 2b study results for its drug Sonelokimab in The Lancet, showing it clears skin in nearly 60% of psoriasis patients. The company plans to accelerate clinical development of the therapy into other inflammatory diseases such as psoriatic arthritis and ankylosing spondylitis. MoonLake holds an in-licence for the antibody fragment from Merck, which originally discovered the molecule alongside Ablynx.PR NewswireFDA approves Cablivi® (caplacizumab-yhdp), the first Nanobody®-based medicine, for adults with acquired thrombotic thrombocytopenic purpura (aTTP)The U.S. Food and Drug Administration has approved Cablivi (caplacizumab-yhdp) for the treatment of acquired thrombotic thrombocytopenic purpura in adults, marking it as the first FDA-approved therapy specifically indicated for this rare blood disorder. Developed by Ablynx and marketed by Sanofi, which acquired the developer in 2018, the drug targets von Willebrand factor to inhibit clot formation and is priced at $270,000 per typical episode.PR NewswireFDA approves first therapy for the treatment of adult patients with a rare blood clotting disorderThe FDA approved Cablivi (caplacizumab-yhdp) for treating acquired thrombotic thrombocytopenic purpura (aTTP), a rare and life-threatening blood clotting disorder, marking the first therapy specifically indicated for this condition. The approval was based on a clinical trial of 145 patients where Cablivi demonstrated faster platelet count improvement and significantly lower recurrence rates (13%) compared to placebo (38%). The FDA granted Priority Review and Orphan Drug designations to Ablynx, which developed the therapy.PR NewswireCablivi™ (caplacizumab) approved in Europe for adults with acquired thrombotic thrombocytopenic purpura (aTTP)The European Commission granted marketing authorization for Cablivi (caplacizumab), making it the first therapeutic specifically approved for acquired thrombotic thrombocytopenic purpura (aTTP), a rare life-threatening blood-clotting disorder with up to 20% mortality rate despite standard treatment. The Phase III HERCULES study demonstrated that caplacizumab significantly shortened time to platelet count response, reduced recurrence rates, and decreased major thromboembolic events compared to placebo. Developed by Ablynx (a Sanofi company), Cablivi represents Sanofi's first Nanobody-based medicine to receive approval and is under priority review by the U.S. FDA with a target decision date of February 6, 2019.GlobeNewswireSANOFI COMPLETES ITS ACQUITISION OF ABLYNX FOLLOWING THE EXPIRATION OF THE SQUEEZE-OUT PROCEDURESanofi completed its acquisition of Ablynx after the squeeze-out period expired on June 12, 2018. The tendered securities were settled on June 19, 2018, with former holders receiving EUR 45 per share and EUR 393,700.78 per convertible bond. Ablynx shares were delisted from Euronext Brussels, NASDAQ, and Frankfurt MTF.GlobeNewswireSanofi : Sanofi completes its acquisition of AblynxSanofi completed its acquisition of Ablynx after the squeeze-out period expired on June 12, 2018. The tendered shares and convertible bonds were settled on June 19, 2018, with un-tendered shares deemed transferred to Sanofi. Ablynx shares were delisted from Euronext Brussels and NASDAQ.GlobeNewswirePUBLICATION IN ACCORDANCE WITH ARTICLE 14 OF THE BELGIAN LAW OF 2 MAY 2007 REGARDING THE PUBLICATION OF MAJOR SHAREHOLDINGS (THE "TRANSPARENCY LAW")Ablynx announced that Farallon Capital, Marshall Wace, Van Herk, and Davidson Kempner crossed the 3% voting-rights threshold. Sanofi's squeeze-out period for remaining shares runs from May 22 to June 12, 2018, after the initial tender offer expired.