Bio-Techne

What Bio-Techne does

Bio-Techne is a Minneapolis-headquartered life sciences company that develops, manufactures, and globally distributes research reagents, analytical instruments, spatial biology platforms, and clinical diagnostics. Its portfolio is organized around four pillars: R&D Systems-branded protein-analysis reagents and instruments (Simple Western/Jess, Maurice iCE/CE-SDS, Simple Plex Ella, Milo single-cell western, Micro-Flow Imaging, Luminex xMAP INTELLIFLEX, and the Pala single-cell sorter); Bio-Techne Spatial (RNAscope in situ hybridization with 80,000+ catalog probes and the COMET automated hyperplex platform from the Lunaphore acquisition, paired with SPYRE antibody panels and HORIZON analysis software); Bio-Techne Diagnostics (AmplideX genetic testing kits, QuantideX oncology kits, clinical chemistry and hematology quality controls, plus contract IVD development and manufacturing under ISO 13485 and cGMP); and a GMP products franchise serving cell-and-gene-therapy manufacturers. The Diagnostics and Spatial Biology segment, derived from the Asuragen, Bionostics, Cliniqa, BiosPacific, Lunaphore, and (until February 2026) Exosome Diagnostics acquisitions, accounted for $81.2 million in Q2 FY2026.

Bio-Techne serves pharmaceutical and biopharmaceutical companies, academic and government research institutions (including NIH, Imperial College London, Memorial Sloan Kettering, and Heidelberg University Hospital), clinical diagnostics laboratories, biosimilar developers, and cell-and-gene-therapy manufacturers. The company sells consumables (proteins, antibodies, ELISA kits, Luminex assays, Simple Plex cartridges, RNAscope probes), capital instruments requiring quotes, custom services (antibody, ELISA, protein, and cell-and-gene-therapy programs), and bulk formulations. Manufacturing spans 15 facilities globally across the United States, Canada, and Europe, and the company is currently subject to a definitive $11.3 billion all-cash acquisition agreement with Merck KGaA announced June 25, 2026 at $73 per share, with closing expected in late 2026 or early 2027.

Revenue is anchored by a consumables mix exceeding 80% of sales, supporting a recurring, largely non-cyclical commercial model. Go-to-market blends direct e-commerce at bio-techne.com, enterprise field sales targeting large pharma and academic centers, phone/email/quote-based instrument sales, and a network of regional distributors. Fiscal 2025 net sales reached $1.219 billion (Q2 FY2026 revenue of $295.9 million was flat year-over-year), gross margins sit in the mid-60s, adjusted operating margin expanded to 31.1% in Q2 FY2026 (up 100bps), and the larger-pharma end market delivered low double-digit growth for five consecutive quarters through Q2 FY2026.

Name

Bio-Techne

Legal name

Bio-Techne Corporation

Website

https://bio-techne.com

Company type

Public

Founded year

1974

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

Bio-Techne is a global life sciences company supplying research reagents, analytical instruments, spatial biology platforms, and clinical diagnostics to pharmaceutical, biotech, academic, and clinical laboratory customers, organized around brands including R&D Systems, ProteinSimple, and Lunaphore.

Ownership category

akta.pro rank

Product category

Life Science Research Tools

NAICS

Analytical Laboratory Instrument Manufacturing (334516), In-Vitro Diagnostic Substance Manufacturing (325413), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Laboratory Analytical Instruments (3826), In Vitro & In Vivo Diagnostic Substances (2835), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industries

Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE), Mass Spectrometry & Spectroscopy Instruments (HLAGAIAB)

Keywords

• Life science reagents
• Analytical instruments
• Spatial biology solutions
• Diagnostic test kits
• Research antibodies

Headquarters

HQ city

Minneapolis

HQ country

United States

HQ region

North America

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales

Revenue model

1. Life Science Research Products: Bio-Techne generates the majority of its revenue from consumable research reagents including recombinant proteins, antibodies, immunoassay kits, and GMP products. Consumables represent over 80% of total sales, providing a recurring revenue base from pharma, biotech, and academic customers.
2. Analytical Instruments: Sale of analytical instruments including Simple Western (Jess), Ella, Maurice, MFI, Luminex, and Pala platforms, along with associated consumables and software. Instruments are sold via direct enterprise sales with quotes.
3. Diagnostics Products and Manufacturing: Molecular diagnostic kits (AmplideX, QuantideX), quality controls, calibrators, and contract development and manufacturing services for IVD developers. Operating under cGMP and ISO 13485 quality systems.
4. Spatial Biology Solutions: Spatial biology platforms including COMET and RNAscope reagents, SPYRE antibody panels, and HORIZON image analysis software, serving translational research and clinical applications.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels6 records

Core offering

Bio-Techne develops, manufactures, and sells life science research reagents (recombinant proteins, antibodies, ELISA kits, small molecules, GMP proteins), analytical instruments (Simple Western, Ella, Maurice, MFI, Luminex, Milo, Pala), spatial biology platforms (RNAscope ISH reagents and COMET hyperplex platform), and clinical diagnostic kits (AmplideX, QuantideX molecular kits, quality controls). Products are sold to pharmaceutical and biotechnology companies, academic and research institutions, and clinical diagnostics laboratories globally across North America, Europe, and Asia.

Product overview

Bio-Techne is a global life sciences company offering an integrated portfolio of research reagents, analytical instruments, and diagnostic products. The portfolio is organized around three core brands: R&D Systems (protein analysis reagents and instruments including Simple Western, Ella, Maurice, Milo, and MFI platforms), Bio-Techne Spatial (spatial biology solutions featuring RNAscope ISH technology and the COMET automated hyperplex platform), and Bio-Techne Diagnostics (clinical diagnostics including AmplideX and QuantideX molecular kits, quality controls, and contract manufacturing services). The company also offers GMP products for biopharmaceutical manufacturing, Luminex multiplexing instruments, and single-cell analysis tools through its comprehensive product ecosystem.

Differentiator

Problem solved

Functional benefit

Brands

• R&D Systems: Trusted protein analysis reagents and instruments brand with decades of innovation
• Bio-Techne Spatial
• Bio-Techne Diagnostics
• COMET Platform
• RNAscope
• Simple Plex
• Cultrex
• Tocris
• Novus Biologicals

Products and services

• Ella Simple Plex Immunoassay Benchtop automated ELISA platform using microfluidic Simple Plex assays for precise reproducible biomarker detection in under 90 minutes with up to 8-plex multiplexing and zero cross-reactivity via four parallel glass nanoreactor channels. For researchers and clinical diagnostics laboratories.
• COMET Spatial Biology Platform Fully automated, high-throughput spatial biology platform integrating staining, imaging, and image preprocessing for walk-away automation of hyperplex multiomics combining RNA and protein detection on the same tissue section. For translational and clinical research customers.
• RNAscope RNA ISH Technology Gold-standard RNA in situ hybridization technology with patented probe design enabling detection, visualization, and quantification of RNA targets at single-molecule level and subcellular resolution with multiplex capability. For academic, pharma, biotech, and clinical research customers.
• Simple Western (Jess) Gel-free, blot-free, fully automated capillary-based Western blot system integrating protein separation and detection with NIR/IR and chemiluminescence detection, multiplex capability, and total protein normalization. For researchers performing quantitative protein expression analysis.
• Maurice Capillary Electrophoresis (iCE/CE-SDS) Capillary electrophoresis instrument for therapeutic protein characterization performing imaged capillary isoelectric focusing (icIEF) and CE-SDS analysis for charge and size heterogeneity, with whole-column imaging, no acrylamide, and green chemistry methods. For biopharmaceutical QC and analytical development.
• Micro-Flow Imaging (MFI) Image-based particle analysis system combining digital microscopy with microfluidics for detection and morphological characterization of sub-visible particles in biopharmaceutical samples with greater than 85% sampling efficiency. For biopharmaceutical QC and biologics manufacturers.
• Milo Single-Cell Western Automated single-cell Western blot platform enabling analysis of protein expression heterogeneity across thousands of individual cells simultaneously. For researchers studying single-cell biology and cell population heterogeneity.
• Pala Single Cell Sorter and Dispenser Microfluidic-based single cell dispenser combining fluorescence sorting with gentle under 2 PSI operation, enabling single cell isolation into 96 or 384-well plates in as little as 2 minutes. For biotech and therapeutic researchers performing single-cell workflows.
• Luminex xMAP INTELLIFLEX Multiplexing instrument enabling detection of up to 500 analytes per sample using xMAP bead-based technology with advanced automation capabilities and xPONENT software for instrument control. For researchers performing high-throughput multiplexed biomarker detection.
• AmplideX Molecular Diagnostic Kits Molecular diagnostic kits for genetic testing using long-read sequencing technology, including FMR1 testing with AGG interruption detection. For clinical diagnostics laboratories performing genetic testing.
• QuantideX Oncology Testing Kits Multiplex molecular diagnostic assays for precision oncology with automated analysis for hematologic malignancies and liquid biopsy applications. For clinical diagnostics laboratories and oncology testing providers.
• Cultrex Extracellular Matrix Products Extracellular matrix products including BME, ECM proteins, and a new synthetic hydrogel for 2D and 3D cell culture supporting organoid and stem cell research applications. For academic and biopharmaceutical researchers.
• SPYRE Antibody Panels Multiplex protein detection antibody reagent panels for use with the COMET spatial biology platform, enabling hyperplex spatial biology applications. For translational and clinical research customers using the COMET platform.
• BaseScope RNA ISH Assay RNA ISH technology designed for detection of short RNA targets (50-300 nucleotides) including splice variants and highly homologous sequences. For researchers requiring short-target RNA in situ hybridization.
• miRNAscope RNA ISH Assay RNA ISH technology for detection of short RNAs (17-50 nucleotides) including small non-coding RNAs, siRNAs, ASOs, and miRNAs. For researchers performing microRNA and small non-coding RNA detection.
• ProximityScope Assay Spatial biology assay designed to reveal functional protein-protein interactions within tissue samples, producing a visual signal only when proteins are in close physical proximity. For researchers studying cell interactions and therapeutic mechanisms.
• Enhanced Leo System Next-generation Leo System combining chemiluminescence and dual-channel fluorescence detection to expand multiplexing and high-throughput protein analysis capabilities for biological research and clinical diagnostics. For researchers and clinical diagnostics laboratories.
• GMP Proteins, Antibodies, and Small Molecules GMP-grade proteins, antibodies, and small molecules for biopharmaceutical manufacturing and cell therapy applications, including a next-generation line of cytokines and growth factors with improved lot-to-lot consistency. For biopharmaceutical manufacturers and cell therapy developers.
• HORIZON Image Analysis Software Image analysis software for the COMET spatial biology platform enabling data extraction and visualization from hyperplex imaging experiments. For COMET platform users in translational and clinical research.
• Quantist Luminex Data Analysis Software Luminex data analysis software compatible with files from all Luminex instruments, enabling intuitive multiplexing data analysis with adjustable curve parameters. For researchers using the Luminex multiplexing platform.

Quantifiable outcome

• Deliveries in under 90 minutes on the Ella platform for biomarker detection
• +3 more outcomes

Named customers4 records

Segments5 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

AI capability3 records

Feature7 records

Partnerships

Nine partnerships are on record, tiered core and minor.

• Wyss Center GenevacoreStrategic or Co-development Partner · 12 December 2025Bio-Techne's spatial biology brand Lunaphore formed a strategic partnership with the Wyss Center Geneva to develop automated 3D multiomics for biomedical research, enhancing tissue analysis techniques and supporting ethical research methodologies.
• Wyss Center for Bio and NeuroengineeringcoreStrategic or Co-development Partner · 11 December 2025Lunaphore (Bio-Techne's spatial biology unit) and the Wyss Center for Bio and Neuroengineering in Geneva announced a strategic collaboration to develop an automated workflow for high-resolution multiomic analysis of 3D tissue samples.
• Monod BiominorOEM/ Whitelabel/ Licensing Partner · 19 November 2025Bio-Techne acquired exclusive rights to a subset of Monod Bio's NovoBody binding proteins, expanding its portfolio of binding proteins for research and diagnostic applications.
• NucleaicoreStrategic or Co-development Partner · 4 November 2025Bio-Techne and Nucleai presented pivotal data from the SECOMBIT clinical trial at SITC 2025, demonstrating AI-powered spatial biology workflow for predictive biomarker discovery in melanoma patients undergoing immunotherapy. The study profiled 42 biopsies, linking immune cell interactions to clinical outcomes.
• ScaleReady (Wilson Wolf Manufacturing / CellReady)coreStrategic or Co-development Partner · 3 November 2025ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation and CellReady, awarded G-Rex Grants to support cell and gene therapy initiatives including Sonoma Biotherapeutics ($300,000), Children's National Hospital (four grants totaling $375,000), Sidra Medicine ($100,000), and Immuneel Therapeutics ($150,000). Over $40 million in commitments supporting CAR-T and gene-modified cell therapy manufacturing.
• Saguaro BiosciencesminorChannel Partner/ Reseller/ Distributor · 15 October 2025Saguaro Biosciences partnered with Bio-Techne to distribute innovative live-cell imaging reagents including ChromaLIVE, NucleoLIVE, and MortaLIVE dyes focused on cell profiling and cytotoxicity screening.
• Oxford Nanopore TechnologiescoreTechnology or Integration · 9 October 2025Bio-Techne expanded its collaboration with Oxford Nanopore Technologies through 2032, focusing on developing genetics products and sequencing kits for genetic disorder screening and diagnosis. The partnership streamlines development and commercialization to enhance genetic testing solutions worldwide.
• Lunaphore Technologies SAcoreTechnology or Integration · 10 July 2023Bio-Techne completed the acquisition of Lunaphore Technologies SA, a Swiss developer of automated spatial biology solutions using microfluidic technology. Lunaphore's COMET platform, antibody panel kits, and image analysis software strengthen Bio-Techne's position in translational and clinical research markets with focus on tissue profiling and rapid tissue staining. Deal expected to close in early fiscal 2024 (announced June 2023, closed July 2023).
• Namocell, Inc.coreTechnology or Integration · 22 June 2022Bio-Techne agreed to acquire Namocell, Inc., specializing in single cell sorting technology integrating microfluidics, flow cytometry, and liquid dispensing, serving biotech and therapeutic research sectors. Deal closed in Q1 FY2023.

Scale indicators9 records

Recent moves7 records

Expansion highlights8 records

Broad incumbents

• Sartorius AG: Bioprocessing and lab products company offering cell line development, bioreactors, and analytical instruments for biopharma manufacturing that overlap Bio-Techne's GMP proteins, Cultrex matrices, and analytical QC instruments for cell and gene therapy manufacturing.
• Lonza Group: Global contract development and manufacturing organization (CDMO) for biologics and cell/gene therapies whose bioprocess services and analytical solutions overlap Bio-Techne's GMP proteins, bioprocess QC instruments, and cell/gene therapy reagent offerings for biopharma manufacturing customers.
• Waters Corporation: Analytical instruments leader in chromatography, mass spectrometry, and lab informatics whose protein characterization and biopharmaceutical QC instruments compete with Bio-Techne's Maurice iCE/CE-SDS and Luminex platforms in pharma/biotech R&D and QC release.
• Bruker Corporation: Scientific instruments provider with mass spectrometry, microscopy, and spatial biology (Canopy Biosciences) franchises that overlap Bio-Techne's analytical instruments and COMET spatial biology platform for proteomics and tissue imaging applications.
• Danaher Corporation: Diversified life sciences and diagnostics conglomerate operating Cytiva, Beckman Coulter, and Pall, with bioprocessing, lab instruments, and diagnostics franchises that directly overlap Bio-Techne's biopharma manufacturing, analytical instruments, and clinical diagnostics segments.
• Agilent Technologies: Analytical instrument and life sciences tools provider with mass spectrometry, chromatography, and cell analysis portfolios that overlap Bio-Techne's analytical instrument lines (Maurice iCE/CE-SDS, Luminex) and reagents for pharma/biotech R&D and QC.
• Thermo Fisher Scientific: Global life sciences tools and diagnostics leader offering reagents, analytical instruments, and biopharma services that overlap directly with Bio-Techne's R&D Systems, ProteinSimple, and Diagnostics portfolios across pharma, biotech, and academic customers.
• Revvity (formerly PerkinElmer): Life sciences and diagnostics company providing reagents, software, and analytics for pharma, biotech, and diagnostics — overlapping with Bio-Techne's immunoassays (Ella), reagents, and clinical diagnostics (AmplideX/QuantideX) offerings.

Direct peers

• 10x Genomics: Pure-play spatial biology and single-cell analytics company offering Visium, Xenium, and Chromium platforms that directly compete with Bio-Techne's RNAscope, COMET hyperplex, and single-cell Western/Pala instruments in translational and clinical research markets.
• Bio-Rad Laboratories: Life sciences research and clinical diagnostics company offering ddPCR, western blotting, and protein analysis workflows that directly compete with Bio-Techne's Simple Western (Jess), digital PCR reagents, and clinical diagnostics portfolio.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• Xx.com/biotechne
• LinkedInlinkedin.com/company/bio-techne

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles18 records

Subsidiaries5 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A16 records

Investments7 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Bio-Techne