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4SC

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uuid0005mng

Namestring
4SC
Legal namestring
4SC AG
Websiteurl
4sc.de
Company typeenum
Public
Founded yearint
1997
Descriptiontext

4SC AG is a German biopharmaceutical company (Aktiengesellschaft) headquartered at Fraunhoferstrasse 22, 82152 Planegg-Martinsried near Munich. Historically the company discovered and developed targeted small-molecule drugs for cancer and autoimmune diseases, with its principal asset Resminostat (marketed as Kinselby) an epigenetic (HDAC-inhibitor) compound intended for haematological and dermatological oncology indications. The firm operated a classic clinical-stage biotech model, generating revenue (where generated) through development milestones, licensing, and partnership arrangements rather than direct sales, with prior partnerships visible across its pipeline page and capital history.

As of the most recent disclosures, 4SC explicitly states on its own website that it 'has currently no products in development and no operational business' and that 'no clinical trials are being conducted'. The company therefore has no live products, no revenue-generating customers, and no active go-to-market motion; contact infrastructure remains in place primarily for residual pharmacovigilance obligations and investor/corporate communications. Ownership is concentrated under Athos KG, which indirectly holds 72.44% of voting rights.

In late 2025 the company executed a structural transaction: following an AGM resolution on 19 September 2025 and a binding tax ruling in November 2025 confirming preservation of tax loss carryforwards, 4SC completed a capital reduction to zero with simultaneous subscription-rights capital increase of approximately EUR 2.7 million on 16 December 2025. This expired all old shares (ISIN DE000A3E5C40) without compensation, removed the company from the Frankfurt Stock Exchange Prime Standard, and re-issued new shares (ISIN DE000A0L1LC2) that are not admitted to stock-exchange trading. The result is a delisted, dormant German public company shell whose principal asset is preserved tax losses and a clean post-restructuring capital structure.

Short descriptiontext

4SC AG is a German biopharmaceutical company that historically developed targeted small-molecule oncology drugs, principally Resminostat (Kinselby); as of late 2025 it has no products in development, no operational business, has delisted from the Frankfurt Stock Exchange, and exists as a dormant public shell with preserved tax loss carryforwards.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
51–100
akta.pro rankint
HeadquartersPlanegg, Germany
HQ citystring
Planegg
HQ countrystring
Germany
HQ regionstring
Europe
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
small molecule drugs, epigenetic drug discovery, cancer therapeutics development, biopharmaceutical research, autoimmune disease drugs
Industry2 codes
1Primary Care & General Medicine Pharmaceuticals
CodeHLAIAAAAPrimaryYes
2Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation)
CodeHLAAAIAIPrimaryNo
NAICS code2 codes
  • Pharmaceutical and Medicine Manufacturing3254
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
SIC code1 code
  • Pharmaceutical Preparations2834
Product category
Biopharmaceutical Oncology Drug Development
Social media profiles2 records
Cost components3 values
Technology or R&D, Personnel, Operations
GTM typeB2B
B2B
Offering typeHardware or Manufacturing
Hardware or Manufacturing
Core offering1 text field

4SC AG historically discovered and developed targeted, small-molecule drugs for the treatment of cancer and autoimmune diseases, with its lead asset being the out-licensed epigenetic oncology drug Resminostat (Kinselby). As stated by the company, 4SC currently has no products in development and no operational business, and is not conducting any clinical trials.

Differentiator
Functional benefit
Problem solved
Product overview1 text field

4SC AG is a German biopharmaceutical company that, as of the source data, has no products in development and no operational business. The company underwent a capital reduction to zero with simultaneous capital increase and delisted from the Frankfurt Stock Exchange in December 2025. The company's sole focus had been on its biopharmaceutical product Resminostat (Kinselby).

Product and service1 record
1Resminostat (Kinselby)
CategoryOut-licensed oncology small-molecule drug
Description

Resminostat (Kinselby) is 4SC AG's lead partnered/out-licensed small-molecule oncology drug candidate, historically positioned for epigenetic (HDAC-inhibitor) treatment of cancer indications. It is listed under 4SC's 'Verpartnerte Produkte' (partnered/out-licensed products) section of the product pipeline.

Scale indicator2 records

Each record includes

Type, Value, Description, Source

Recent move7 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight3 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

US clinical-stage oncology company developing HDAC inhibitor entinostat, the most direct mechanistic peer to 4SC's Resminostat program. Comparable in epigenetic-modulator approach and oncology focus.

TypeDirect peer
Description

Clinical-stage biotech focused on targeted oncology including epigenetic and small-molecule approaches. Directly comparable to 4SC's prior small-molecule oncology discovery model.

3MEI Pharma
TypeDirect peer
Description

Small-cap clinical oncology company with HDAC inhibitor (pracinostat) experience and similar pipeline-focused, partnership-driven business model to 4SC's historical operations.

TypeRegional player
Description

German biotech platform company providing drug discovery and development services. Comparable as a fellow Munich-area biotech with small-molecule expertise, though broader and operationally active unlike dormant 4SC.

TypeRegional player
Description

German biotech (now part of Novartis) historically focused on hematology/oncology therapeutics. Comparable as a German small-cap oncology developer that underwent major corporate transformation.

TypeRegional player
Description

German clinical-stage oncology company developing antibody-targeted therapeutics. Comparable as a small-cap German biotech with a similar operating scale and oncology focus.

TypeRegional player
Description

German clinical-stage immuno-oncology company. Comparable as a small German biotech listed in Germany that has undergone restructuring and pipeline refocusing, similar in scale and stage.

TypeBroad incumbent
Description

Japanese pharmaceutical group that previously held development and commercialization rights to Resminostat in Japan. Directly comparable as a former partner/competitor in the Resminostat franchise.

TypeEmerging player
Description

Clinical-stage oncology company that has undergone multiple transformations and restructurings. Comparable trajectory to 4SC's transition into a dormant or transformed entity.

TypeBroad incumbent
Description

French pharmaceutical group active in oncology. Relevant as a potential commercialization partner for any relicensed 4SC oncology assets given the European oncology overlap.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses5 records

Each record includes

Headline, Details, Source

Competitive moat2 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights4 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Ideal customer profile1 record

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles6 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds8 records

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors9 records

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment2 records

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

4SC

Biopharmaceutical Oncology Drug Development4sc.de

4SC AG is a German biopharmaceutical company that historically developed targeted small-molecule oncology drugs, principally Resminostat (Kinselby); as of late 2025 it has no products in development, no operational business, has delisted from the Frankfurt Stock Exchange, and exists as a dormant public shell with preserved tax loss carryforwards.

What 4SC does

4SC AG is a German biopharmaceutical company (Aktiengesellschaft) headquartered at Fraunhoferstrasse 22, 82152 Planegg-Martinsried near Munich. Historically the company discovered and developed targeted small-molecule drugs for cancer and autoimmune diseases, with its principal asset Resminostat (marketed as Kinselby) an epigenetic (HDAC-inhibitor) compound intended for haematological and dermatological oncology indications. The firm operated a classic clinical-stage biotech model, generating revenue (where generated) through development milestones, licensing, and partnership arrangements rather than direct sales, with prior partnerships visible across its pipeline page and capital history.

As of the most recent disclosures, 4SC explicitly states on its own website that it 'has currently no products in development and no operational business' and that 'no clinical trials are being conducted'. The company therefore has no live products, no revenue-generating customers, and no active go-to-market motion; contact infrastructure remains in place primarily for residual pharmacovigilance obligations and investor/corporate communications. Ownership is concentrated under Athos KG, which indirectly holds 72.44% of voting rights.

In late 2025 the company executed a structural transaction: following an AGM resolution on 19 September 2025 and a binding tax ruling in November 2025 confirming preservation of tax loss carryforwards, 4SC completed a capital reduction to zero with simultaneous subscription-rights capital increase of approximately EUR 2.7 million on 16 December 2025. This expired all old shares (ISIN DE000A3E5C40) without compensation, removed the company from the Frankfurt Stock Exchange Prime Standard, and re-issued new shares (ISIN DE000A0L1LC2) that are not admitted to stock-exchange trading. The result is a delisted, dormant German public company shell whose principal asset is preserved tax losses and a clean post-restructuring capital structure.

4SC firmographics

Firmographics
Name
4SC
Legal name
4SC AG
Website
https://4sc.de
Company type
Public
Founded year
1997
Operating status
Operating
Headcount range
51–100 employees
Short description
4SC AG is a German biopharmaceutical company that historically developed targeted small-molecule oncology drugs, principally Resminostat (Kinselby); as of late 2025 it has no products in development, no operational business, has delisted from the Frankfurt Stock Exchange, and exists as a dormant public shell with preserved tax loss carryforwards.
Ownership category
akta.pro rank

4SC industry classification

Industry
Product category
Biopharmaceutical Oncology Drug Development
NAICS
Pharmaceutical and Medicine Manufacturing (3254), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
SIC
Pharmaceutical Preparations (2834)
akta.pro primary industry
Primary Care & General Medicine Pharmaceuticals (HLAIAAAA)
akta.pro secondary industry
Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation) (HLAAAIAI)

Keywords

  • Small molecule drugs
  • Epigenetic drug discovery
  • Cancer therapeutics development
  • Biopharmaceutical research
  • Autoimmune disease drugs

Where 4SC is headquartered

Location

Headquarters

HQ city
Planegg
HQ country
Germany
HQ region
Europe

Offices1 record

Markets served

4SC business model

Business model
GTM type
B2B
Offering type
Hardware or Manufacturing
Cost components
Technology or R&D, Personnel, Operations

4SC product offering

Product offering

Core offering

4SC AG historically discovered and developed targeted, small-molecule drugs for the treatment of cancer and autoimmune diseases, with its lead asset being the out-licensed epigenetic oncology drug Resminostat (Kinselby). As stated by the company, 4SC currently has no products in development and no operational business, and is not conducting any clinical trials.

Product overview

4SC AG is a German biopharmaceutical company that, as of the source data, has no products in development and no operational business. The company underwent a capital reduction to zero with simultaneous capital increase and delisted from the Frankfurt Stock Exchange in December 2025. The company's sole focus had been on its biopharmaceutical product Resminostat (Kinselby).

Differentiator

Problem solved

Functional benefit

Products and services

  • Resminostat (Kinselby) Resminostat (Kinselby) is 4SC AG's lead partnered/out-licensed small-molecule oncology drug candidate, historically positioned for epigenetic (HDAC-inhibitor) treatment of cancer indications. It is listed under 4SC's 'Verpartnerte Produkte' (partnered/out-licensed products) section of the product pipeline.

Companies that use 4SC

Customer profile

Ideal customer profiles1 record

4SC technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

4SC partnerships and signals

Strategic signal

Scale indicators2 records

Recent moves7 records

Expansion highlights3 records

4SC competitors and assessment

Company assessment

Direct peers

  • Syndax Pharmaceuticals: US clinical-stage oncology company developing HDAC inhibitor entinostat, the most direct mechanistic peer to 4SC's Resminostat program. Comparable in epigenetic-modulator approach and oncology focus.
  • Curis: Clinical-stage biotech focused on targeted oncology including epigenetic and small-molecule approaches. Directly comparable to 4SC's prior small-molecule oncology discovery model.
  • MEI Pharma: Small-cap clinical oncology company with HDAC inhibitor (pracinostat) experience and similar pipeline-focused, partnership-driven business model to 4SC's historical operations.

Regional players

  • Evotec SE: German biotech platform company providing drug discovery and development services. Comparable as a fellow Munich-area biotech with small-molecule expertise, though broader and operationally active unlike dormant 4SC.
  • MorphoSys: German biotech (now part of Novartis) historically focused on hematology/oncology therapeutics. Comparable as a German small-cap oncology developer that underwent major corporate transformation.
  • Heidelberg Pharma: German clinical-stage oncology company developing antibody-targeted therapeutics. Comparable as a small-cap German biotech with a similar operating scale and oncology focus.
  • Medigene AG: German clinical-stage immuno-oncology company. Comparable as a small German biotech listed in Germany that has undergone restructuring and pipeline refocusing, similar in scale and stage.

Broad incumbents

  • Otsuka Holdings: Japanese pharmaceutical group that previously held development and commercialization rights to Resminostat in Japan. Directly comparable as a former partner/competitor in the Resminostat franchise.
  • Pierre Fabre: French pharmaceutical group active in oncology. Relevant as a potential commercialization partner for any relicensed 4SC oncology assets given the European oncology overlap.

Emerging players

  • NewLink Genetics (LumiraDx-era assets): Clinical-stage oncology company that has undergone multiple transformations and restructurings. Comparable trajectory to 4SC's transition into a dormant or transformed entity.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat2 records

Key risks6 records

Key highlights4 records

Customer concentration

4SC social profiles

Digital presence

4SC financial estimates

Financial estimate

Revenue estimate

Valuation estimate

4SC leadership team

Management profile

Number of profiles

Profiles6 records

4SC funding detail

Funding detail

Funding overview

Funding rounds8 records

Investors9 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

4SC M&A and investment

M&A and investment

M&A

Investments2 records

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about 4SC

What does 4SC do?

4SC AG historically discovered and developed targeted, small-molecule drugs for the treatment of cancer and autoimmune diseases, with its lead asset being the out-licensed epigenetic oncology drug Resminostat (Kinselby). As stated by the company, 4SC currently has no products in development and no operational business, and is not conducting any clinical trials.

Is 4SC a public or private company?

4SC is a public company. It is classified as private equity controlled and is currently operating.

When was 4SC founded?

4SC was founded in 1997. It employs 51 to 100 people.

Where is 4SC based?

4SC is headquartered in Planegg, Germany, in the Europe region.

Who are 4SC's main competitors?

Direct peers on record are Syndax Pharmaceuticals, Curis and MEI Pharma. Regional players are Evotec SE, MorphoSys, Heidelberg Pharma and Medigene AG. Broad incumbents are Otsuka Holdings and Pierre Fabre. NewLink Genetics (LumiraDx-era assets) is listed as an emerging player.

Does 4SC have an API?

No public API is recorded for 4SC.

What industry is 4SC in?

4SC's product category is Biopharmaceutical Oncology Drug Development. Its primary akta.pro industry code is HLAIAAAA, Primary Care & General Medicine Pharmaceuticals, with a secondary code of HLAAAIAI, Target Identification & Validation Platforms (omics-driven, chemoproteomics, genetic validation). Its NAICS code is 3254 and its SIC code is 2834.

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Live signals
PR NewswireImmunic, Inc. Reports Year End 2021 Financial Results and Highlights Recent ActivityImmunic, Inc. reported year-end 2021 financial results, including a net loss of approximately $92.9 million compared to $44.0 million in 2020, driven by increased R&D expenses of $61.1 million. The company announced positive clinical progress across its pipeline, including completion of enrollment in its phase 2 CALDOSE-1 trial for ulcerative colitis, enrollment of the first patient in its phase 3 ENSURE program for multiple sclerosis, and positive phase 1 results for IMU-935 in psoriasis and mCRPC. Immunic AG also settled its remaining 4.4% royalty obligation to 4SC AG for $17.25 million.PR NewswireImmunic, Inc. Reports Second Quarter 2021 Financial Results and Highlights Recent ActivityImmunic, Inc. reported second quarter 2021 financial results with a net loss of $17.9 million, compared to a net loss of $11.5 million in Q2 2020, driven by increased R&D expenses of $15.7 million. The company received FDA clearance to initiate phase 3 ENSURE trials for IMU-838 in relapsing-remitting multiple sclerosis and a supportive phase 2 CALLIPER trial in progressive multiple sclerosis, while also raising $45 million in July financing. Immunic settled its remaining royalty obligation to 4SC AG for $17.3 million and ended Q2 2021 with $87.2 million in cash and cash equivalents, expected to fund operations into 2023.PR NewswireImmunic and 4SC AG Sign Agreement Regarding the Settlement of Royalty Obligations for Immunic's Lead Program, IMU-838Immunic, Inc. and 4SC AG have signed an agreement for Immunic to settle its remaining 4.4% royalty obligation on net sales of its lead drug candidate IMU-838 for $17.25 million, payable 50% in cash and 50% in Immunic common stock. The transaction completes all payment obligations between the two companies and gives Immunic full ownership of future sales potential for IMU-838, which is being developed for multiple sclerosis, ulcerative colitis, Crohn's disease, COVID-19, and primary sclerosing cholangitis. For 4SC, the settlement provides non-dilutive financing extending its cash runway into the second half of 2022 to support its oncology programs.PR NewswireProstate Cancer Pipeline H1 2017 Therapeutic Key Players 3-V Biosciences Inc, 4SC AG, Actinium Pharmaceuticals Inc and Advaxis Inc, Says a New Research Report at RnRMarketResearch.comRnRMarketResearch released the 'Prostate Cancer Pipeline Review, H1 2017', a comprehensive report analyzing the global therapeutic landscape for prostate cancer. The document details pipeline data for over 1,800 drugs across various development stages and profiles key industry participants including major pharmaceutical firms and biotech companies.GlobeNewswireDGAP-Adhoc: 4SC AG: 4SC provides headline results from Yakult Honsha's Phase II trial of resminostat in combination with sorafenib as first line therapy in liver cancerYakult Honsha completed its Phase II trial of resminostat plus sorafenib in 170 Asian patients with advanced liver cancer. The combination did not meet the primary endpoint of prolonged time to disease progression versus sorafenib alone, so Yakult Honsha will not conduct a pivotal study. Patients with high ZFP64 expression showed longer TTP.GlobeNewswireDGAP-Adhoc: 4SC AG plans to issue new shares to finance the further development of its epigenetic lead anti-cancer compound resminostat4SC AG resolved to issue up to 8.2 million new shares via a rights offering, targeting gross proceeds of EUR 24-29 million, and to swap a shareholder loan from Santo Holding into equity. The funds will finance a Phase II trial of resminostat for cutaneous T-cell lymphoma, with potential European approval. The company also plans further trials and partnerships.GlobeNewswireDGAP-NVR: 4SC AG: Release according to Article 26a of the WpHG [the German Securities Trading Act] with the objective of Europe-wide distribution4SC AG announced its total voting rights as of April 2015, amounting to 10,169,841 voting rights. The announcement was transmitted by DGAP, a service of EQS Group AG, under Article 26a of the German Securities Trading Act.GlobeNewswireDGAP-Adhoc: 4SC Signs Licensing and Development Agreement with Menarini for Resminostat in Asia-Pacific Excluding Japan4SC AG and Menarini Asia-Pacific signed a licensing and development agreement for resminostat in the Asia-Pacific region excluding Japan. Menarini will receive exclusive rights and pay up to €95 million in upfront and milestone payments, with royalties on sales. The partnership targets liver cancer, where over 75% of cases occur in the region.GlobeNewswireDGAP-AFR: 4SC AG: Announcement according to Articles 37v, 37w, 37x et seqq. of the WpHG [the German Securities Act] with the objective of Europe-wide distribution4SC AG announced the disclosure dates for its 2014 financial reports, including annual, half-year, and quarterly reports. The annual report is due March 26, 2014, the Q2 report August 7, 2014, Q1 May 8, 2014, and Q3 November 6, 2014. The announcement is transmitted by DGAP, a service of EQS Group AG.GlobeNewswireDGAP-NVR: 4SC AG: Release according to Article 26a of the WpHG [the German Securities Trading Act] with the objective of Europe-wide distribution4SC AG announced its total voting rights as of November 2014, amounting to 50,849,206 shares. The announcement was transmitted by DGAP, a service of EQS Group AG, under Article 26a of the German Securities Trading Act.