What Perricone MD does

Perricone MD is a US-based, science-backed skincare brand founded by dermatologist Dr. Nicholas Perricone in 1998 (firmographic record also cites 1997) and currently operated as part of The Hut Group's (LSE: THG) beauty portfolio. The company sells a multi-collection portfolio of anti-aging and specialty skincare products — including the Neuropeptide, High Potency Classics, Cold Plasma Plus+, Vitamin C Ester, Hypoallergenic Clean Correction, Acne Relief, and No Makeup Skincare lines, plus internal supplements — directly to consumers through its owned e-commerce site perriconemd.com, with subscription auto-replenishment (20-38% savings) and selective premium third-party retail placement (e.g., Nordstrom). Product pricing spans roughly $19 for cleansers to $405 for premium moisturizers such as the Cold Plasma Plus+ Advanced Hydrating Complex.

The brand's competitive positioning rests on proprietary formulation technology developed over more than 25 years, including neuropeptide complexes, DMAE, a proprietary Vitamin C Ester, the Cold Plasma Plus+ delivery system with MicroSperse technology, a Hyaluronic 4+2 Complex, a Triple Retinol Blend, and Acyl-Glutathione. Clinical and consumer study claims cited on owned marketing materials include 100% of participants showing hydration improvement, 97% reporting healthier-looking skin after 28 days, 91% reporting reduction in fine lines and wrinkles after 28 days, and 94% reporting improved skin barrier function after 28 days.

The revenue model combines one-time DTC purchases and recurring subscription revenue, supplemented by retail partnerships and a tiered loyalty program (Perricone Plus+ Rewards). Multiple installment-payment integrations (Afterpay, Klarna, Sezzle) and FSA/HSA eligibility reduce purchase friction. With 51-100 employees, the brand operates as a focused, digitally native premium skincare franchise within THG's broader portfolio, led by a corporate team that includes a CFO (Stephen Hsu) and SVP of Digital Marketing & Ecommerce (Mike Janover), with Dr. Nicholas Perricone serving as Founder and Chairman.

Name

Perricone MD

Legal name

Perricone MD

Website

https://perriconemd.com

Company type

Private

Founded year

1998

Operating status

Operating

Headcount range

51–100 employees

Short description

Perricone MD is a US-based science-backed skincare brand operating a multi-collection DTC portfolio of anti-aging and specialty skincare products, owned by The Hut Group (LSE: THG), and selling directly to consumers through its website and premium retail partners.

Ownership category

akta.pro rank

Product category

Cosmeceutical Skincare

NAICS

Cosmetics, Beauty Supplies, and Perfume Retailers (456120)

SIC

Perfumes, Cosmetics & Other Toilet Preparations (2844), Soap, Detergents, Cleang Preparations, Perfumes, Cosmetics (2840)

akta.pro primary industry

Treatment Skincare (Serums, Actives, Acne & Anti-aging) (CRABAAAB)

akta.pro secondary industries

Dermocosmetics & Medical-Grade Skincare (CRABAAAF), Sensitive Skin & Barrier Repair (CRABAAAG), Eye & Lip Skincare (CRABAAAC)

Keywords

• Anti-aging skincare
• Cosmeceutical products
• Neuropeptide technology
• Dermatologist skincare brand
• Nutricosmetic supplements

Headquarters

HQ city

San Francisco

HQ country

United States

HQ region

North America

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Marketing or Sales, Supply Chain, Operations, Personnel, Technology or R&D, Infrastructure

Revenue model

1. Direct Product Sales (E-commerce): Perricone MD generates revenue through direct-to-consumer sales via its owned e-commerce website. Products are sold at various price points ranging from $19 for cleansers to $405 for premium moisturizers. One-time purchases and subscription models are available.
2. Auto-Replenishment Subscriptions: Subscription service offering 20-38% savings on recurring orders with free delivery after first order. Customers can control frequency with options from 1-6 month cycles. Subscription customers earn enhanced rewards points.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels6 records

Core offering

Perricone MD develops, manufactures, and sells science-backed cosmeceutical skincare products (cleansers, serums, moisturizers, eye treatments, toners, masks, body care, haircare, and tinted skincare) along with nutricosmetic supplements, organized into collections such as Neuropeptide, High Potency Classics, Cold Plasma Plus+, Vitamin C Ester, Hypoallergenic Clean Correction, Acne Relief, and No Makeup Skincare. Products are sold direct-to-consumer via perriconemd.com with an Auto Replenishment subscription offering 20-38% recurring savings, and selectively through third-party retailers such as Nordstrom.

Product overview

Perricone MD is a science-backed skincare brand offering a comprehensive portfolio of skincare products organized into distinct collections and sub-brands. The product ecosystem includes: (1) Neuropeptide Collection - the brand's most advanced high-performance anti-aging line featuring neuropeptides for mature skin concerns; (2) High Potency Classics Collection - foundational skincare with signature ingredients like DMAE, Vitamin E, and retinol; (3) Cold Plasma Plus+ Collection - advanced technology formulations for comprehensive skin transformation; (4) Vitamin C Ester Collection - brightening line with proprietary Vitamin C Ester; (5) Hypoallergenic Clean Correction - gentle products for sensitive skin; (6) Acne Relief - targeted solutions for acne-prone skin; (7) No Makeup Skincare - products providing makeup-like coverage with skincare benefits; and (8) Supplements - internal skincare support. Individual products span serums, moisturizers, cleansers, eye treatments, toners, masks, and body care. The brand also offers a subscription service (Auto Replenishment) and loyalty program (Perricone Plus+ Rewards).

Differentiator

Problem solved

Functional benefit

Products and services

• Neuropeptide Deep Crease Serum High-performance serum powered by neuropeptide technology that helps make wrinkle depth appear shallower and minimizes the look of expression lines around the mouth, eyes, lips, and forehead; targeted at consumers with mature skin concerns.
• Neuropeptide Eyelid Lift Serum Serum designed to improve the look of sagging, crepey eyelids and reduce the appearance of eyelid creases and darkness using neuropeptide technology; for consumers concerned with aging around the eyes.
• Neuropeptide Corrective Brightening Under-Eye Cream Rich corrective eye cream that visibly tightens, softens, and illuminates the eye area to reduce dark circles, crow's feet, and under-eye bags; formulated with neuropeptide technology for mature skin concerns.
• Neuropeptide Pro-Strength Firming Moisturizer Advanced moisturizer designed to visibly firm and lift skin, improving elasticity and restoring a more youthful appearance; uses neuropeptide technology for mature skin.
• Neuropeptide Firming Facial Concentrate Concentrated treatment that delivers intensive firming benefits and improves overall skin resilience using neuropeptide technology.
• Neuropeptide Rejuvenating Moisturizer Broad Spectrum SPF 25 Moisturizer with built-in broad-spectrum SPF 25 sun protection that also delivers anti-aging benefits to rejuvenate and protect skin using neuropeptide technology.
• Neuropeptide The Cleansing Balm Melt-away balm cleanser that removes stubborn makeup, dirt, and debris while replenishing and nourishing skin for a radiant complexion; formulated with neuropeptide technology.
• Neuropeptide Pore-Refining & Resurfacing Cream Cleanser Cream cleanser that refines pores and resurfaces skin texture while gently cleansing; powered by neuropeptide technology.
• Neuropeptide Lift & Correct Duo Bundled duo combining Neuropeptide Deep Crease Serum and Eyelid Lift Serum to target deep-set wrinkles and sagging eyelids for a more youthful appearance.
• High Potency Classics Face Finishing & Firming Moisturizer Rose-scented moisturizer from the High Potency Classics line that deeply moisturizes and treats skin for a luminous-looking complexion; consumer study reported 97% agreed skin looked healthier and 91% saw reduced fine lines & wrinkles after 28 days.
• High Potency Hyaluronic Intensive Body Therapy Lightweight body therapy featuring the Hyaluronic 4+2 Complex (4 forms and 2 natural building blocks of hyaluronic acid) for immediate, intense hydration that visibly firms and smooths skin; HSA/FSA eligible.
• High Potency Retinol Recovery Overnight Moisturizer Rich overnight moisturizer using three forms of retinol to support skin's natural recovery and renewal, reducing lines and wrinkles while delivering intense hydration; clinical study showed 100% of participants had significant improvement in skin hydration.
• High Potency Classics Hyaluronic Intensive Moisturizer Gel-cream moisturizer with three forms of hyaluronic acid delivering intense hydration for plumper, healthier-looking skin; consumer study reported 94% improved skin barrier function and 97% said skin looked & felt filled with hydration immediately.
• High Potency Hyaluronic Intensive Hydrating Serum Deeply nourishing serum with 4 forms and 2 natural building blocks of hyaluronic acid for immediate and deep hydration, visibly plumping and smoothing the complexion.
• High Potency Intensive Smoothing Serum High-concentration niacinamide serum that visibly smooths rough skin texture for a more refined, even-looking complexion.
• High Potency Face Finishing & Firming Toner Daily lightweight toner that gently sloughs off dead skin cells, unclogs pores, and visibly tightens for a firmer, more refined complexion.
• Cold Plasma Plus+ Advanced Hydrating Complex Multi-tasking moisturizer using Cold Plasma Plus+ with MicroSperse delivery for all-day hydration, visibly reducing lines, wrinkles, loss of elasticity, and uneven texture.
• Vitamin C Ester Citrus Brightening Cleanser Non-drying face wash with proprietary Vitamin C Ester that cleanses without stripping natural oils, visibly improving clarity, texture, and tone.
• Day-to-Night Firming Duo Curated two-product firming bundle anchored by the #1 bestselling Tinted Moisturizer, providing continuous firming, hydration, and protection from morning to night.
• Day-to-Night Treat & Renew Kit Curated four-product routine kit that deeply hydrates, visibly firms, and leaves skin glowing with health from morning to night.
• Moisturizer Trio Bundled set of three Perricone MD moisturizers — Cold Plasma Plus+ Intensive Hydrating Complex, Essential Fx Acyl Glutathione Intensive Overnight Moisturizer, and High Potency Face Finishing & Firming Moisturizer — priced at $79 (regular $369).
• High Potency Triple Retinol Renewal Eye Serum Eye serum using a triple retinol blend to target visible signs of aging around the eyes.
• High Potency Classics Face Finishing & Firming Tinted Moisturizer Broad Spectrum SPF 30 Brand's #1 bestselling tinted moisturizer offering all-day hydration with a luminous tint and broad-spectrum SPF 30 sun protection, supported by the Three Tier philosophy (Perfect, Prevent, Protect).
• Perricone MD Supplements Internal nutricosmetic supplements designed to support skin health from within as part of a comprehensive inside-out skincare regimen.
• Auto Replenishment Subscription Recurring subscription service offering up to 30% savings on auto-replenishment orders, free delivery after first order, and flexible 1-6 month scheduling with no commitment.
• Perricone Plus+ Rewards Loyalty Program Tiered loyalty program allowing customers to earn points on purchases, redeem for discounts, and access exclusive offers and benefits; subscription customers earn enhanced rewards points.

Quantifiable outcome

• 97% agreed skin looked healthier after 28 days of use
• +5 more outcomes

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

Feature7 records

Scale indicators4 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• SkinCeuticals: Premium dermatologist-developed skincare brand owned by L'Oréal, focused on advanced anti-aging, vitamin C, and corrective serums. Highly comparable to Perricone MD on science-backed positioning, treatment-serum hero SKUs, and premium pricing.
• Dr. Dennis Gross Skincare: Dermatologist-founded prestige skincare brand best known for at-home peels and retinol treatments. Directly comparable to Perricone MD on physician authority, treatment-serum hero SKUs, and prestige department-store/dermatology channel presence.
• SkinMedica: Dermatologist-founded treatment skincare brand (now Allergan Aesthetics/AbbVie) offering growth factors, retinols, and chemical peels. Closely matches Perricone MD's physician-founded science narrative and clinical-results positioning.
• Tatcha: Premium skincare brand owned by Unilever, emphasizing proprietary ingredients and elegant formulations. Comparable to Perricone MD on premium price positioning, DTC + prestige retail hybrid model, and proprietary technology storytelling.
• Colorescience: Mineral-based dermatologist-recommended skincare and SPF brand. Comparable to Perricone MD on physician-credibility positioning, premium pricing, and the SPF/tinted moisturizer overlap seen in Perricone MD's Tinted Moisturizer SPF 30 hero SKU.
• Drunk Elephant: Premium clean-clinical skincare brand owned by Shiseido, with strong digital-first DTC and Sephora distribution. Comparable to Perricone MD on premium serums/moisturizers, ingredient-led storytelling, and millennial/Gen-X affluent consumer targeting.
• Dermalogica: Professional-grade skincare brand sold through licensed skin therapists and select retail. Comparable to Perricone MD on professional/clinical credibility, treatment-serum category leadership, and global distribution model.

Emerging players

• Allies of Skin: Premium clinical skincare brand with a focused treatment-serum assortment and cult following. Comparable to Perricone MD on prestige treatment-serum positioning and digital-first GTM, though smaller scale and narrower assortment.

Broad incumbents

• Estée Lauder (Skincare Division): Multi-brand prestige beauty conglomerate owning Advanced Night Repair, Re-Nutriv, and clinician brands. Comparable as a broad incumbent overlapping Perricone MD's anti-aging and serum categories through its portfolio rather than direct brand competition.
• L'Oréal Luxe (Skincare): Luxury division of L'Oréal housing Lancôme, Helena Rubinstein, SkinCeuticals, and La Roche-Posay. Relevant as the broad incumbent parent ecosystem competing with Perricone MD across multiple premium skincare segments.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/perriconemd
• Instagraminstagram.com/perriconemd
• Xx.com/perriconemd
• YouTubeyoutube.com/user/perriconemd
• LinkedInlinkedin.com/company/perricone-md

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Perricone MD