What EnzymoCore does

EnzymoCore Ltd. is an Israeli private biotechnology company founded in 2007 by Dr. Sobhi Basheer (formerly co-founder of NASDAQ-listed Enzymotec) to commercialize proprietary immobilized enzyme technology for biodiesel production and omega-3 fatty acid enrichment. The company's core technology centers on methanol-resistant immobilized lipases covalently bound to specialized carriers, which catalyze esterification and transesterification simultaneously, enabling conversion of feedstocks with 0–100% free fatty acid content — including used cooking oil, brown grease, animal fats and acid oils — into ASTM and EN specification biodiesel at 99%+ conversion efficiency. Flagship products include TransZyme A (biodiesel biocatalyst), TransZyme ET and OmegaZyme ET (omega-3 EPA/DHA enrichment for nutraceuticals), all protected by 6 US patents plus additional international filings.

The company monetizes through three streams: (1) direct enzyme/biocatalyst sales priced at $150-300 per kg, (2) licensing of its proprietary enzymatic process technology to joint-venture partners who fund plant operations and feedstock procurement, and (3) engineering services delivered in partnership with Meptagon (EPCM partner, 550+ engineers). EnzymoCore operates a partnership-led go-to-market: 50:50 joint ventures with Nordtraube (Peru, 2015) and ANTAN (Germany, 2016), plus collaboration agreements with M-Energy (South Korea, 30,000 t/y), Luming Green (Shanghai pilot), Maida One (Thailand, 20,000 t/y retrofitted plant), and Zohar Dalia (Israel). Cumulative disclosed external capital is approximately $2.4 million in equity (AquAgro Fund, 2008) and roughly $985,000 in grants (BIRD-F 2009, EISMEA 2018); revenue is not publicly disclosed. The company is led by co-CEOs Dr. Sobhi Basheer and Nehemya Zamosh, with operations spanning six countries.

Name

EnzymoCore

Legal name

EnzymoCore Ltd.

Website

https://enzymocore.com

Company type

Private

Founded year

2007

Operating status

Operating

Headcount range

1–10 employees

Short description

EnzymoCore is an Israeli biotechnology company that develops and licenses proprietary immobilized enzyme biocatalysts (TransZyme A, TransZyme ET, OmegaZyme ET) for enzymatic biodiesel production from low-grade feedstocks and for omega-3 EPA/DHA enrichment in nutraceuticals, serving biodiesel producers and functional-food manufacturers through joint ventures and technology licensing.

Ownership category

akta.pro rank

Product category

Industrial Biotechnology & Biocatalysts

NAICS

Fats and Oils Refining and Blending (311225)

SIC

Industrial Organic Chemicals (2860), Fats & Oils (2070)

akta.pro primary industry

Biodiesel (FAME) Production (EUAAAHAC)

akta.pro secondary industries

Biofuels & Renewable Fuels Switching (Biomethane/RNG, Bio-oils, Sustainable Biomass) (EUABAJAD), Bio-based Food & Flavor Ingredients (Non-fuel Co-products: sweeteners, organic acids, flavors) (EUAAAIAJ)

Keywords

• Immobilized enzyme biocatalysts
• Biodiesel production technology
• Omega-3 fatty acid enrichment
• Enzymatic transesterification catalysts
• Lipase enzyme products

Headquarters

HQ city

Shafa `amr

HQ country

Israel

HQ region

Middle East

Offices5 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Supply Chain, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Enzyme/Biocatalyst Sales: Sale of proprietary immobilized enzyme products (TransZyme A, TransZyme ET, OmegaZyme ET) to biodiesel and functional food producers. Pricing is $150-300 per kg enzyme depending on volume.
2. Technology Licensing: Licensing of proprietary enzymatic technology to joint venture partners worldwide. Partners receive rights to use patents, process technology, and receive ongoing enzyme supply.
3. Engineering Services: Process design, engineering support, and technical assistance for plant setup and operation through partnership with Meptagon.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels6 records

Core offering

EnzymoCore develops and commercializes proprietary immobilized enzyme-based biocatalysts, primarily its flagship TransZyme A lipase product, for the production of ASTM and EN specification biodiesel from low-grade feedstocks including used cooking oil, brown grease, animal fats, and high free fatty acid (0-100% FFA) materials. The company also offers TransZyme ET and OmegaZyme ET biocatalysts for omega-3 EPA and DHA enrichment in fish and algal oils for nutraceutical applications, licensing its patented technology through joint ventures and direct sales to biodiesel producers and functional food companies worldwide.

Product overview

EnzymoCore is a technology company providing immobilized enzyme-based biocatalysts for two main industries: biodiesel production and functional foods (omega-3 concentrates). The core product is TransZyme A, an immobilized lipase enzyme for biodiesel production that handles feedstocks with 0-100% free fatty acids. The company also offers HighOmega branded products including TransZyme ET and OmegaZyme ET biocatalysts for omega-3 EPA/DHA enrichment in fish and algal oils. All products are protected by multiple international patents.

Differentiator

Problem solved

Functional benefit

Brands

• TransZyme A: Flagship immobilized enzyme biocatalyst product for biodiesel production, transforming glycerides and FFAs to fatty acid methyl esters
• TransZyme ET
• OmegaZyme ET
• HighOmega

Products and services

• TransZyme A Flagship immobilized lipase enzyme biocatalyst for production of fatty acid methyl esters (biodiesel) from all types of feedstocks with 0-100% free fatty acid content, including used cooking oil, brown grease, animal fats, and acid oils. Transforms all glycerides (tri-, di-, mono-glycerides) and FFAs in presence of methanol to fatty acid methyl esters, with glycerol and water as byproducts; produces 3,000-5,000 tons of biodiesel per ton of enzyme.
• TransZyme ET Biocatalyst for production of high concentrations of EPA and DHA omega-3 fatty acids in the form of fatty acid ethyl esters from fish and algal oils, for nutraceutical and functional food applications.
• OmegaZyme ET Biocatalyst for production of high concentrations of EPA and DHA omega-3 fatty acids in glyceride form characterized by high stability and bioavailability, for nutraceutical and functional food applications.
• HighOmega Branded omega-3 fatty acid concentrate product line and dedicated website (high-omega.com) featuring EnzymoCore's proprietary enzymatic technology for producing high-concentration EPA and DHA omega-3 ingredients for the functional food industry.
• Enzymatic Biodiesel Production Technology (Technology Licensing) Licensed process technology package for enzymatic biodiesel production, providing joint venture partners with patents, process know-how, enzyme supply, and engineering support to build and operate commercial-scale biodiesel plants from second and third generation feedstocks.

Quantifiable outcome

• 3,000-5,000 tons of biodiesel produced per ton of enzyme
• +5 more outcomes

Named customers7 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Nine partnerships are on record, tiered core and secondary.

• ANTANcoreStrategic or Co-development Partner · 1 January 201650:50 joint venture with German company ANTAN for first enzyme-based Biodiesel plant in Leipzig, Germany. Strategic commercial relationship with leading company in German biodiesel industry, one of the most advanced territories with favorable regulations, tax benefits, and incentives.
• Nordtraube PerucoreStrategic or Co-development Partner · 1 August 201550:50 joint venture with Peruvian company Nordtraube in Lima/Peru for first joint enzyme-based Biodiesel plant in Peru. Joint venture combines immobilized enzyme experience with biodiesel expertise, global vision with local relevance. Technology designed for Peruvian and international markets.
• M EnergycoreStrategic or Co-development Partner · 1 November 2013Collaboration with Korean biodiesel producer M-Energy for enzymatic process development. International joint research project supported by Israeli and Korean governments. Produced 30,000 tonnes/year of ASTM biodiesel using brown grease feedstock extracted from grease trap and FOG (fat, oil, grease) materials.
• Luming GreensecondaryStrategic or Co-development Partner · 1 January 2013Pilot plant operator in Shanghai/China making biodiesel from used cooking oil. Pilot plant (1.0 ton/day capacity) uses EnzymoCore immobilized enzymes as production catalysts.
• PurolitesecondaryStrategic or Co-development Partner · 1 November 2009US company partner in BIRD-F government grant ($800,000) for commercialization of enzyme process using 2nd generation feedstocks. Purolite develops, produces, and distributes specialty resins for ion exchange, adsorbents, and catalyst applications.
• Zohar DaliasecondaryStrategic or Co-development Partner · 1 November 2009Israeli surfactant manufacturer where EnzymoCore installed first pilot plant for enzymatic biodiesel production in November 2009. First company to use EnzymoCore's immobilized enzyme process. Uses glycerol byproduct for liquid soap production.
• MeptagoncoreImplementation/ SI/ Consulting PartnerStrategic engineering partner with 60 years of experience in design, plant engineering, and construction (EPCM). Meptagon provides turnkey solutions for enzymatic biodiesel plants from early design through implementation and trials. Meptagon employs 550+ people with expertise across mechanical, electrical, and process engineering disciplines.
• Appalachian BiofuelssecondaryStrategic or Co-development PartnerUS joint venture partnership to produce 28 million gallons per year (MMgy) using EnzymoCore's immobilized enzyme technology in Russell County, Virginia.
• Maida OnesecondaryStrategic or Co-development PartnerThai company that retrofitted from chemical to EnzymoCore's enzymatic process on commercial scale of 20,000 tonnes/year using used cooking oil (November 2012).

Scale indicators10 records

Recent moves8 records

Expansion highlights5 records

Broad incumbents

• Novozymes (Novonesis): Global enzyme leader (now Novonesis after merger with Chr. Hansen) with broad biodiesel lipase offerings and enzyme R&D scale orders of magnitude larger than EnzymoCore. Comparable as a direct competing supplier of lipase biocatalysts to the biodiesel industry.
• DSM (now dsm-firmenich): Large life sciences and nutrition company with an enzymes business serving biofuels, animal nutrition, and food ingredients including omega-3 (veramaris). Comparable as a broad incumbent competing in both biodiesel enzymes and omega-3 concentrates.
• Enzymotec: Biofunctional lipid ingredient company (formerly NASDAQ-listed) co-founded by Dr. Sobhi Basheer, developing omega-3 and phospholipid ingredients for nutraceuticals. Highly comparable as the founder's prior platform in the same enzyme-based lipid ingredient space.
• Neste: Global leader in renewable diesel (HVO/HEFA) made from waste and residue feedstocks. Comparable as a large incumbent in renewable fuels competing for the same waste-feedstock-to-fuel mandate that EnzymoCore's enzymatic biodiesel serves.
• Archer Daniels Midland (ADM): Diversified agribusiness with biodiesel production and an omega-3 (onavita) ingredient business. Comparable as a large incumbent operating across both of EnzymoCore's biodiesel and omega-3 verticals.
• Renewable Energy Group (now part of Chevron): One of North America's largest biodiesel producers, now part of Chevron, operating plants using multiple feedstock pathways. Comparable as a large incumbent biodiesel producer that could be a customer or competitor for enzyme technology.

Direct peers

• AB Enzymes (ABF Ingredients): Specialty industrial enzyme manufacturer offering esterification and biodiesel enzyme products. Direct competitor to TransZyme A in the immobilized-lipase-for-biodiesel niche.
• Codexis: Engineered enzyme company with biodiesel and other industrial biocatalyst programs, using directed evolution to design lipases. Comparable as a technology-driven enzyme developer serving fuels and industrial chemistry customers.

Others

• Purolite (Ecolab): Specialty resin and carrier supplier for immobilized enzymes, and EnzymoCore's BIRD-F grant partner. Comparable as the enabling carrier/adsorbent vendor whose materials support EnzymoCore's immobilized enzyme products.

Regional players

• Verbio: German biodiesel and bioethanol producer with enzymatic biodiesel operations comparable to EnzymoCore's German JV with ANTAN. Comparable as a European regional player in the same biodiesel value chain.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Profiles10 records

Subsidiaries2 records

Funding overview

Funding rounds2 records

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about EnzymoCore