What Aseptic Technologies does

Aseptic Technologies SA is a Belgian private company, founded in 2002 and headquartered in Gembloux (Crealys Science Park), that develops, manufactures, and markets aseptic fill & finish equipment and consumables for the pharmaceutical and biotech industries. Its core platform is the AT-Closed Vial® — a pre-assembled, radiation-sterilized polymer vial (Cyclic Olefin Copolymer body, Thermoplastic Elastomer stopper) that is sealed before filling and accessed through the stopper with a non-coring needle, mechanically reclosed, laser-re-sealed, then capped — paired with filling lines ranging from the semi-automated Crystal M1 (up to 200 vials/hour, installed in a biosafety cabinet) through the Crystal L1 (up to 500/hr in RABS), Cellana L1/XL1 (up to 700/hr isolated), to the commercial-scale Crystal PX (up to 4,500 vials/hour). Aseptic Technologies has been a member of SKAN Group since 2011 and in 2025 absorbed Plast4Life (its prior Simonis JV) to vertically integrate clean injection molding, with capacity scheduled to double by 2027; Aseptic Technologies also distributes through Sartorius Stedim Biotech (AT-Connector as Gammasart ATD™) and Yukon Medical (AT-Adapt). Customer-validated regulatory milestones include Drug Master Files on file with the US FDA for AT-Closed Vial® and AT-Cap™, ISO 9001:2015 and ISO 15378:2017 certifications, and approved drug products using the technology spanning FDA, EMA, MHRA, PMDA, Health Canada, and TGA — covering major commercial cell and gene therapies (Casgevy, Carvykti, Vyjuvek, Ryoncil, Ebvallo, Delytact, Beqvez, Durveqtix) and one veterinary biologic (ArtiCell Forte).

The company monetizes through four revenue streams: (i) capital equipment sales (Crystal M1/pure² M1/spectra M1/L1/XL1/PX filling lines and ancillary devices such as AT-Cellyx and AT-Etcher), with quote-based pricing tied to configuration and containment type; (ii) consumables and single-use systems (AT-Closed Vial®, AT-Cap, AT-Assembly, AT-Connect/AT-Connector, AT-Adapt, AT-Nest, AT-CryoBox, AT-Tray) delivered sterile (SAL 10⁻⁶), generating repeat purchases from each installed base; (iii) AT Academy training and LifeCycle Support services covering installation, IQ/OQ qualification, preventive maintenance, spare parts, retrofits, and remote/on-site support, delivered via SKAN's global LCS organization; and (iv) an irrevocable, non-exclusive, royalty-free worldwide license to fill and sell filled containers using AT-Closed Vial® technology within a defined field of use. Go-to-market is direct enterprise field sales with quote-based, multi-year contracts, complemented by channel partners (Sartorius Stedim, Yukon Medical) and thought-leadership content (webinars, case studies, industry events) targeting advanced therapy developers, CDMOs, hospital pharmacies, and next-generation biologics developers across Europe, North America, and Asia-Pacific.

Name

Aseptic Technologies

Legal name

Aseptic Technologies SA

Website

https://aseptictech.com

Company type

Private

Founded year

2002

Operating status

Operating

Headcount range

11–50 employees

Short description

Aseptic Technologies SA, a Belgian private subsidiary of SKAN Group (founded 2002, Gembloux), designs and manufactures AT-Closed Vial® polymer vials and a portfolio of aseptic fill & finish equipment (Crystal M1 through Crystal PX) plus single-use systems for pharmaceutical, biotech, CDMO, hospital pharmacy, and advanced therapy customers worldwide.

Ownership category

akta.pro rank

Product category

Pharmaceutical Aseptic Fill & Finish Equipment

NAICS

Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (3345), Surgical Appliance and Supplies Manufacturing (339113)

SIC

Gaskets, Packg & Sealg Devices & Rubber & Plastics Hose (3050), Wholesale-Medical, Dental & Hospital Equipment & Supplies (5047)

akta.pro primary industry

Aseptic Processing, Fill-Finish & Sterile Manufacturing Tech (isolators, lyophilization interfaces) (HLAAAJAG)

akta.pro secondary industries

Filling & Dosing Equipment (Liquid, Powder, Aseptic) (IMALAOAB), Sterile Fill-Finish & Aseptic Manufacturing CDMO (HLAGABAH), Fill-Finish & Aseptic Drug Product Manufacturing (Biologics/ATMP) (HLAGAGAG), Sterile & Aseptic Medical Packaging (Pouches, Wraps, Sterile Barriers) (IMALAIAB)

Keywords

• Aseptic fill finish
• Closed vial technology
• Pharmaceutical filling equipment
• Cell gene therapy manufacturing
• Clean injection molding

Headquarters

HQ city

Gembloux

HQ country

Belgium

HQ region

Europe

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Supply Chain, Technology or R&D, Operations, Infrastructure, Marketing or Sales

Revenue model

1. Aseptic Filling Equipment Sales: Sale of aseptic filling machines including Crystal M1, pure² M1, spectra M1, Crystal L1, Cellana L1, Cellana XL1, and Crystal PX filling lines. Equipment is sold directly to pharmaceutical and biotech companies, CDMOs, hospital pharmacies, and academic institutions. Pricing is quote-based with lead times varying by product (e.g., Crystal M1 delivered in 6 weeks; L1 in RABS installed and qualified in 1 week).
2. Consumables and Single-Use Systems: Recurring revenue from consumables including AT-Closed Vial® (in AT-CryoBox, AT-Nest, AT-Tray formats), AT-Cap, AT-Assembly (single-use fluid path), AT-Connect, AT-Connector, AT-Adapt, AT-Nest, AT-CryoBox packaging. Consumables are delivered sterile (SAL 10⁻⁶) and are repeat-purchase items for customers running filling operations.
3. LifeCycle Support (LCS) Services: Comprehensive service contracts and standalone services covering installation, IQ/OQ qualification, preventive maintenance, operator and advanced technical training (AT Academy), troubleshooting (remote and on-site), spare parts supply, and retrofit/upgrade services. LCS team is based across SKAN locations worldwide.
4. AT-Closed Vial® and AT-Cap Licensing: AT-Closed Vial® Technology is subject to industrial property rights. At the date of transfer of property, AT provides the product user and its successors an irrevocable, non-exclusive worldwide royalty-free license to fill containers and sell filled containers using the AT-Closed Vial® Technology within the defined Field of use (vaccines, cell therapy, and injectable substances for human/veterinary applications).

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels7 records

Core offering

Aseptic Technologies designs, manufactures, and sells aseptic fill & finish solutions for the pharmaceutical industry, centered on the proprietary AT-Closed Vial® polymer vial system. The product portfolio spans semi-automated tabletop filling stations (Crystal M1), isolated filling units (pure² M1, spectra M1), robotic lines in RABS/isolators (Crystal L1, Cellana L1, Cellana XL1), and high-speed commercial filling lines (Crystal PX up to 4,500 vials/hour), along with single-use devices, aseptic transfer systems, ancillary equipment, and LifeCycle Support services.

Product overview

Aseptic Technologies offers a comprehensive aseptic fill & finish portfolio centered on the AT-Closed Vial technology - a polymer vial system where vials are closed before filling, eliminating contamination risks. The product line spans from manual tabletop systems (Crystal M1) to fully automated high-speed lines (Crystal PX), and includes single-use devices (AT-Assembly, AT-Adapt, AT-Port System) and ancillary equipment (AT-Cellyx, AT-Etcher). Services include clean injection molding, single-use system manufacturing, and LifeCycle Support. The company operates as a member of SKAN Group, combining AT-Closed Vial technology with SKAN isolators for integrated solutions.

Differentiator

Problem solved

Functional benefit

Brands

• AT-Closed Vial®: Ready-to-fill polymer vials (COC) with TPE stoppers that are closed before filling, designed for aseptic fill & finish and cryogenic storage of cell and gene therapy products.
• Crystal M1
• pure² M1
• spectra M1
• Crystal L1 Robot Line
• Cellana L1 Robot Line
• Cellana XL1
• Crystal PX
• AT-Port System
• AT-Assembly
• AT-Cellyx
• AT-Etcher

Products and services

• AT-Closed Vial® Ready-to-fill polymer vials (COC body, TPE stopper) closed before filling, molded and assembled in ISO 5 conditions; available in volumes from 1 mL to 50 mL with validated Container Closure Integrity during cryopreservation down to liquid nitrogen temperatures. Used by pharmaceutical and biotech companies for aseptic fill & finish of cell therapies, gene therapies, vaccines, and injectable biologics.
• Crystal M1 Filling Station Tabletop semi-automated aseptic filling system for small batches, processing up to 200 AT-Closed Vials per hour with filling volumes from 0.1 mL to 50 mL. Designed for installation in a biosafety cabinet or isolator, installed and qualified in 1 day. For cGMP small-batch manufacturing, process development, and R&D.
• pure² M1 Plug-and-play isolated fill & finish unit combining AT-Closed Vial® technology with SKAN pure² isolator shell. Dedicated to small cGMP batches; no HVAC connection required; fast H2O2 decontamination.
• spectra M1 Isolated fill & finish unit combining AT-Closed Vial® technology with SKAN spectra isolator, featuring integrated nanox catalyst and skanfog decontamination for optimized cycles in small cGMP batches.
• Crystal L1 Robot Line in RABS Semi-automated robotic aseptic filling line with active Restricted-Access Barrier System (RABS), processing up to 500 AT-Closed Vials per hour; installed in Grade B environment with minimal footprint. Installed and qualified in 1 week.
• Cellana L1 Robot Line Automated isolated fill & finish line processing up to 500 vials per hour with 100% weight in-process control; integrated H2O2 decontamination system enables installation in lower-class cleanroom environments.
• Cellana XL1 Robot Line

Quantifiable outcome

• 500+ equipment units in operation globally
• +6 more outcomes

Named customers13 records

Segments5 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature10 records

Partnerships

Three partnerships are on record, tiered core and key.

• SKAN GroupcoreStrategic or Co-development PartnerAseptic Technologies has been a member of SKAN Group since 2011. SKAN is a Swiss global market leader for isolators, cleanroom devices, and decontamination processes for aseptic biopharmaceutical production. The partnership combines Aseptic Technologies' AT-Closed Vial® filling technology with SKAN's isolator design (pure², spectra, Cellana). Together they provide integrated fill & finish solutions for ATMP products, from cell processing to plug-and-play isolated filling. SKAN LifeCycle Support experts provide worldwide service coverage for Aseptic Technologies equipment.
• Sartorius Stedim BiotechkeyChannel Partner/ Reseller/ DistributorSartorius Stedim Biotech distributes the AT-Connector (large-volume aseptic liquid transfer device for use with AT-Port System) under the brand name Gammasart Aseptic Transfer Device (ATD™). This partnership extends Aseptic Technologies' market reach into Sartorius Stedim's extensive bioprocessing customer base worldwide.
• Yukon MedicalkeyChannel Partner/ Reseller/ DistributorYukon Medical is the exclusive worldwide distributor of the AT-Adapt, a dedicated stand-alone disposable device for needle-free vial access designed for use with AT-Closed Vial® by healthcare professionals in hospitals and pharmacies.

Scale indicators5 records

Recent moves5 records

Expansion highlights6 records

Direct peers

• IMA Life (IMA S.p.A.): Italian-headquartered manufacturer of aseptic processing and filling equipment for the pharmaceutical industry, including vial filling, lyophilization, and isolation technology. Overlaps directly with Aseptic Technologies' aseptic fill-finish equipment portfolio.
• Stevanato Group: Italian manufacturer of pharmaceutical glass containers (vials, syringes, cartridges) and integrated fill-finish equipment, including the EZ-fill® ready-to-use platform. Direct competitor offering both primary packaging and aseptic filling solutions overlapping with AT-Closed Vial and the Crystal/PX lines.
• Syntegon Technology (formerly Bosch Packaging Technology): Global supplier of processing and packaging equipment for the pharmaceutical industry, including aseptic fill-finish systems for vials, ampoules, and prefilled syringes. Direct peer in aseptic filling equipment serving pharma, biotech, and CDMO customers.
• Bausch + Strobel Machine Company: German manufacturer of aseptic filling and closing machines for vials, syringes, and cartridges used in pharmaceutical manufacturing. Direct competitor to Aseptic Technologies' Crystal M1, L1, XL1, and PX filling lines in sterile fill-finish equipment for injectables.

Broad incumbents

• Gerresheimer AG: European-based manufacturer of pharmaceutical glass and plastic primary packaging (vials, syringes, bottles, containers) plus devices and solutions for injectables. Competes broadly in primary packaging formats for sterile injectable drugs, overlapping with AT-Closed Vial's positioning.
• Becton, Dickinson and Company (BD): Global medical technology company whose BD Medical segment supplies prefillable syringe systems, vials, and drug delivery devices for injectable pharmaceuticals. A broad incumbent in primary container and delivery systems competing for ATMP fill-finish specifications.
• West Pharmaceutical Services: Global leader in elastomeric closures, seals, and primary packaging components for injectable drug delivery, with growing portfolio of polymer-based container systems and integrated delivery platforms. Adjacent competitor in primary container components used in aseptic fill-finish.
• Schott AG (SCHOTT Pharma): Leading manufacturer of pharmaceutical glass vials, ampoules, syringes, and cartridges serving the global injectables market. Competes as the incumbent primary packaging format versus AT-Closed Vial's polymer alternative, and is investing in polymer/specialty containers for biologics.

Others

• Cytiva (Danaher): Global bioprocessing supplier offering cell culture, filtration, single-use, and process development technologies for biologics and cell/gene therapy manufacturing. Adjacent peer serving overlapping customer base (CDMOs, ATMP developers) rather than competing directly in fill-finish equipment or vials.
• Sartorius Stedim Biotech: Global bioprocessing supplier of single-use technologies, fluid management, and aseptic transfer solutions, and existing channel partner for AT-Connector (distributed as Gammasart ATD™). Comparable in single-use fluid-path and aseptic transfer categories rather than direct filling equipment.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/aseptictechnologies

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles3 records

Subsidiaries1 record

Funding overview

Funding rounds2 records

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Aseptic Technologies