Motus GI

What Motus GI does

Motus GI Holdings, Inc. is a publicly traded medical device company (NASDAQ: MOTS) headquartered in Fort Lauderdale, Florida, with operational roots in Tirat Carmel, Israel. The company develops and commercializes the Pure-Vu EVS System, an FDA-cleared intraprocedural cleansing device designed to improve visualization during colonoscopy and upper GI endoscopy by rapidly clearing blood, clots, debris, and residue from the GI tract during the procedure. The system combines proprietary components — Pulsed Vortex Irrigation, Smart Sense Suction, an Oversleeve, and a workstation — and has demonstrated statistically significant improvements in Boston Bowel Prep Scale ratings in clinical studies (adequate prep rates rising from 38% to 96%, and 31% to 98% in multi-center trials), addressing a clear unmet need around inadequate bowel preparation that drives procedure cancellations, repeat colonoscopies, and extended hospital stays.

The company generates revenue primarily through hardware sales of the Pure-Vu System and associated disposable kits to hospitals and endoscopy centers, supplemented by maintenance services under standard terms. Motus employs a direct enterprise field sales motion targeting gastroenterologists, endoscopy units, and facility administrators at acute care hospitals and academic medical centers, with marketing emphasis on clinical evidence, peer-reviewed publications, conference presentations (DDW, ACG, UEGW), video testimonials, and a clinical evidence library accessed through the corporate website.

The commercial footprint remains narrow. Operations are confined to the United States, the headcount is in the 11–50 range, and the public reference base consists of a small set of academic medical centers including Northwestern Memorial Hospital, UCLA, Massachusetts General Hospital, and UCI Health. The company has raised approximately $50 million across three disclosed rounds (a 2016 equity round led by Perceptive Advisors, a 2019 Silicon Valley Bank facility, and a 2021 Kreos Capital facility), and continues to rely on debt and structured financing instruments to fund commercialization of a single product line.

Name

Motus GI

Legal name

Motus GI Holdings, Inc.

Website

https://motusgi.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

11–50 employees

Short description

Motus GI develops and commercializes the Pure-Vu EVS System, an FDA-cleared intraprocedural cleansing device that improves visualization during colonoscopy and upper GI endoscopy, sold direct to US hospitals and academic medical centers.

Ownership category

akta.pro rank

Product category

Endoscopy Medical Devices

NAICS

Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Endoscopy Systems & Accessories (Scopes, Cameras, Light Sources, Insufflation) (HLAHADAB)

akta.pro secondary industries

Endoscopic Therapeutic & Access Devices (Trocars, dilators, biopsy/ablation tools) (HLAHADAN), General Gastroenterology (HLAKAEAA)

Keywords

• Endoscopic cleansing devices
• Colonoscopy visualization systems
• GI endoscopy equipment
• Intraprocedural bowel preparation
• Medical device manufacturing

Headquarters

HQ city

Tirat Carmel

HQ country

Israel

HQ region

Middle East

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain

Revenue model

1. Medical Device Sales: Sale of Pure-Vu System devices including workstation, colon kits, and disposable components to hospitals and outpatient endoscopy centers.
2. Maintenance Services: Maintenance services offered for the Pure-Vu equipment as indicated by General Terms and Conditions of Maintenance Services documentation.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels5 records

Core offering

Motus GI develops, manufactures, and sells the Pure-Vu EVS System, an intraprocedural endoscopic cleansing device that attaches to standard colonoscopes and upper GI endoscopes. The system clears blood, blood clots, debris, and residue from the GI tract during the procedure, enabling successful completion of colonoscopy and upper GI endoscopy in patients with inadequate bowel preparation. Revenue is generated through sale of the workstation, colon kits, disposable components, and associated maintenance services to hospitals and outpatient endoscopy centers.

Product overview

Motus GI offers the Pure-Vu EVS System as its primary product offering. This is a single unified medical device designed to address inadequate bowel preparation during endoscopy procedures. The system integrates with standard colonoscopy and upper GI endoscopy workflows to provide rapid intraprocedural cleansing, improving visualization from a baseline of 38% adequate preparation to 96% following use. The product consists of a distal end component, oversleeve, workstation, and colon kit components. The company positions the Pure-Vu System as addressing the unmet clinical need for improving colonoscopy outcomes when patients have poor bowel preparation.

Differentiator

Problem solved

Functional benefit

Brands

• Pure-Vu: Medical device system for improving visualization during colonoscopy and upper GI endoscopy procedures through intraprocedural cleansing technology.
• Pure-Vu EVS

Products and services

• Pure-Vu EVS System

Quantifiable outcome

• Adequate bowel preparation rate improved from 38% to 96% following use of Pure-Vu System
• +4 more outcomes

Named customers4 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Scale indicators4 records

Recent moves5 records

Expansion highlights4 records

Broad incumbents

• Fujifilm Healthcare: Endoscopy systems and accessories competitor with strong presence in colonoscopy. Comparable as a broad incumbent whose installed base creates potential channel conflict or partnership opportunity for Pure-Vu.
• Medtronic (GI Solutions): Operates a GI-focused business including PillCam and endoscopy-adjacent products. Relevant as a large diversified medtech incumbent with the resources to enter the intraprocedural cleansing category.
• US Endoscopy (Steris): Steris-owned business focused on GI endoscopy accessories including cleaning and irrigation devices. Most direct head-to-head competitor to Pure-Vu in intraprocedural colon cleansing, backed by Steris's global sales infrastructure.
• Boston Scientific: Major GI endoscopy franchise (including hemostasis, EMR, and resection tools). Comparable as a broader endoscopy incumbent whose installed base and channel could support an intraprocedural cleansing offering competing with Pure-Vu.
• Pentax Medical (HOYA): HOYA-owned endoscopy system manufacturer with significant presence in GI endoscopy. Could extend into intraprocedural cleansing accessories as part of an integrated colonoscopy workflow.
• Olympus Corporation: Dominant player in GI endoscopy systems and accessories. Olympus could trivially bundle a competing intraprocedural cleansing feature into its colonoscopy platform, representing the largest competitive threat to Pure-Vu's niche.

Direct peers

• ERBE USA: Manufacturer of electrosurgical and irrigation/suction equipment used in GI endoscopy. Comparable as a peer providing procedural devices (including irrigation platforms) that compete for the same hospital budget and workflow position.
• Cook Medical (GI Endoscopy): Cook Medical's Endoscopy division manufactures a broad portfolio of GI accessories and devices. Comparable as a direct competitor in the GI endoscopy accessory category, with overlapping hospital customers.

Emerging players

• EndoGastric Solutions: Smaller medtech company operating in the GI endoscopy space with devices addressing procedural challenges. Comparable as a similarly sized emerging player navigating hospital sales with a niche endoscopic technology.
• Ovesco Endoscopy: German-based developer of advanced GI endoscopy devices including therapeutic accessories. Comparable as an emerging niche player in GI endoscopy accessories with hospital-channel commercialization.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights5 records

Customer concentration

• YouTubeyoutube.com/channel/UCrHVRI1wwZKgBzD2DT37sgQ
• LinkedInlinkedin.com/company/10597881
• Xx.com/Motus_GI

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds3 records

Investors8 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Motus GI