What Axle Informatics does

Axle Informatics is a privately held, Woman-Owned Small Business federal contractor specializing in biomedical research, information technology, and healthcare solutions for U.S. federal agencies, primarily the National Institutes of Health and its constituent institutes. Founded in 2002 and headquartered in Rockville, Maryland with additional offices in McLean, Virginia and Frederick, Maryland, the company operates three integrated service lines: Research (scientific program management, basic/translational/clinical research, computational biology, lab automation, and data science), Technology (AI/ML, cloud, cybersecurity, and custom software engineering), and Healthcare (population health analytics and clinical authentication platforms).

The company's technology portfolio centers on the Unified NCATS Auth (UNA) platform — a cloud-based federation and identity management service handling 400,000+ logins across 150+ applications — and the Axlerator Healthcare Authentication Solution, which provides passwordless badge-tap authentication natively integrated with Epic EHR workflows. AI/ML capabilities span large language model implementation, NLP, computer vision (deployed at scale on 1.3M+ antiviral screening images and 1B+ brain images), generative AI, MLOps, and multi-omic data integration. The company maintains ISO 27001, ISO 9001, ISO 20000-1, CMMI SVC/3, and CMMI DEV/3 certifications.

Axle's revenue is generated almost exclusively through federal contract vehicles, including the five-year, $3.6 billion ceiling NIH SOAR prime contract, GSA OASIS+ (WOSB and Small Business pools), NIAID PSTSS, NCATS STSS, NHLBI ITAC, and NIH OTSS. Pricing is negotiated through government procurement and not publicly disclosed. The company employs 501-1,000 staff supporting these engagements, with leadership including founder/CEO Vidya Chari Sharma, COO Gary Mays (SES-certified), and a bench of VPs overseeing Technology, Data Science, Corporate Development, Strategic Growth, and Automation.

Name

Axle Informatics

Legal name

Axle Informatics LLC

Website

https://axleinfo.com

Company type

Private

Founded year

2002

Operating status

Operating

Headcount range

251–500 employees

Short description

Axle Informatics is a Woman-Owned Small Business federal contractor providing biomedical research, AI/ML, cloud, and healthcare authentication solutions primarily to NIH and federal health agencies under vehicles like NIH SOAR ($3.6B) and GSA OASIS+.

Ownership category

akta.pro rank

Product category

Federal Government IT and Research Services

NAICS

Computer Systems Design and Related Services (54151), Other Scientific and Technical Consulting Services (54169), Computer Systems Design and Related Services (5415)

SIC

Services-Computer Integrated Systems Design (7373), Services-Engineering, Accounting, Research, Management (8700)

akta.pro primary industry

Healthcare IT & Health Informatics Staffing (BPACADAK)

akta.pro secondary industries

Operating Room Integration & Surgical Informatics (OR control, documentation, connectivity) (HLAHADAE), Multi-Condition RPM Platforms & Care Orchestration (device-agnostic, population management) (HLALAFAL)

Keywords

• Federal contract services
• Biomedical research support
• Healthcare identity management
• AI and machine learning solutions
• Government IT services

Headquarters

HQ city

Rockville

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Federal Government Contracts: Axle Informatics generates revenue primarily through federal government contract vehicles including GSA OASIS+, NIH SOAR ($3.6B five-year contract), NIAID PSTSS, NCATS STSS, and NHLBI ITAC. These are multi-year, large-scale contracts supporting NIH biomedical research programs
2. Healthcare Technology Solutions: Provides healthcare authentication, population health analytics, and clinical informatics solutions to healthcare organizations, government agencies, and research institutions

Go-to-market motion1 record

Distribution channels3 records

Marketing channels4 records

Core offering

Axle Informatics is a federal contractor that delivers biomedical and translational research support, scientific program management, and enterprise IT services to government agencies, primarily NIH and its institutes. It complements these services with proprietary technology offerings including the Unified NCATS Auth (UNA) identity management platform and the Axlerator Healthcare Authentication Solution for passwordless, Epic-integrated clinical workflows. Its portfolio spans AI/ML, cloud, cybersecurity, data science, and healthcare authorization solutions delivered through vehicles such as NIH SOAR ($3.6B) and GSA OASIS+.

Product overview

Axle Informatics offers a comprehensive suite of research, technology, and healthcare solutions structured as a platform-plus-modules portfolio. The Research division encompasses Scientific Program Management, Regulatory Support, Basic and Translational Research, Computational Biology, Core Research Technologies, Lab Automation, IT for Research, Data Science (including Software Integrations, Data Services, Data Education, and Scientific Computing), and Biomedical Research spanning Basic Research, Translational Research, Clinical Research, and Computational Biology. The Technology division provides AI/ML Solutions (LLM, NLP, Computer Vision, Generative AI, MLOps), Cloud Solutions (Migration, Architecture, Cloud-Native Development, Multi-Cloud, Security, Sustainability), Cybersecurity (ATO, Compliance, SOC), and Digital Solutions (Custom Software, App Support, Architecture, Low Code/No Code, Data Visualization). The Healthcare division centers on the Axlerator Identity Solutions platform — a unified Healthcare Authentication Solution comprising Clinical Authorization Fabric, Endpoint and Workstation Security, Epic EHR Authorization Workflow, and Unified Application Integration — alongside Population Health Analytics and Healthcare Operations. Axle also holds major federal contract vehicles including NIH SOAR ($3.6B), GSA OASIS+ WOSB Pool, NIAID PSTSS, NCATS STSS, NIH OTSS, and NHLBI ITAC ADS BPA, and developed the UNA (Unified NCATS Auth) identity management system for NCATS.

Differentiator

Problem solved

Functional benefit

Products and services

• Scientific Program Management Strategic program development, contract and grant management, risk management, resource optimization, and stakeholder engagement for complex research initiatives, delivered to federal research clients such as NIH.
• Biomedical Research Services (Basic, Translational, and Clinical) End-to-end biomedical research capabilities including basic exploratory studies, translational bench-to-bedside initiatives, clinical trial design, and computational biology for federal research clients.
• Core Research Technologies and Lab Automation Advanced instrumentation, high-throughput screening systems, imaging and analysis tools, laboratory automation, robotics, and AI-driven data collection systems for modern research environments.
• Data Science Services (Software, Data Services, Education, Scientific Computing) Data software and platform integration, advanced data analytics, big data processing, data literacy training, and high-performance scientific computing delivered to federal research programs.
• NIH SOAR (Scientific, Operations, and Administrative Resources) Contract Five-year, $3.6 billion prime federal contract under which Axle provides research, program implementation, and operational support across NIH's biomedical research mission.
• GSA OASIS+ WOSB and Small Business Contract Vehicles Best-in-class GSA OASIS+ IDIQ vehicles in the WOSB and Small Business pools providing flexible procurement access for complex non-IT professional services across the federal government over a 10-year ordering period.
• NIAID PSTSS / NCATS STSS / NIH OTSS / NHLBI ITAC ADS Contract Vehicles Agency-specific contract vehicles (NIAID PSTSS, NCATS STSS, NIH OTSS, NHLBI ITAC ADS BPA) delivering professional, scientific, technical, agile development, data science, and strategy services to NIH institutes.
• Unified NCATS Auth (UNA) Identity Platform Cloud-based federation, authorization, and identity management service that Axle designed, implemented, and maintains for the NCATS research community, enabling secure access across 150+ government and academic applications with integrations across inCommon, Login.gov, N3C, CTSA, SmartIRB, AWS, and CLAD.
• Axlerator Healthcare Authentication Solution (Clinical Authorization Fabric) Unified healthcare authorization platform that secures endpoint access, Epic EHR workflows, and clinical applications through a single clinician-first, policy-driven, phishing-resistant, passwordless authentication experience.
• Endpoint and Workstation Security (Tap-and-Go Passwordless Access) Passwordless, phishing-resistant authentication using a badge tap to secure shared workstations, WOW carts, and private PCs in clinical environments under granular policy control.
• Epic EHR Authorization Workflow Passwordless, badge-tap single sign-on into Epic EHR that preserves patient context across care transitions and propagates identity into VDI/Citrix sessions for native Epic workflows.
• Unified Application Integration SSO Single policy engine that extends phishing-resistant authentication and granular per-application controls across modern, legacy, thick-client, and virtualized clinical applications.
• AI/ML Solutions (LLM, NLP, Computer Vision, Generative AI, MLOps, Predictive Analytics) Enterprise AI/ML offerings including LLM implementation and integration, NLP for sentiment, entity, and summarization, predictive analytics, MLOps pipelines, generative AI, AI governance, and computer vision for object detection and image analysis.
• Cloud Solutions (Migration, Architecture, Cloud-Native Development, Multi-Cloud, Security, Sustainability) End-to-end cloud services spanning migration, solution architecture, cloud-native development and managed services, hybrid and multi-cloud operations, cloud security, and sustainability practices.
• Cybersecurity Solutions (ATO, Compliance, SOC, Risk and Regulatory) Cybersecurity services covering ATO assessments, compliance frameworks, incident management, security operations center (SOC) design, and risk and regulatory compliance for federal and commercial clients.
• Digital Solutions (Custom Software, App Support, Architecture, Low Code/No Code, Data Visualization) Full-stack custom web, mobile, and desktop software development, application support and maintenance, systems architecture and design, low code/no code solutions, and data visualization services.
• Population Health Analytics and Solutions Population health management capabilities spanning health information exchange, virtual population health ecosystems, and real-world evidence (RWE) analytics for drug development and healthcare policy insights.
• Healthcare Operations Services Predictive healthcare analytics, healthcare data analytics and optimization, EHR implementation and process automation, and general healthcare operational support services.

Quantifiable outcome

• 20-fold reduction in quality assurance visualization time and 100-fold decrease in discovery cycle time for antiviral screening
• +4 more outcomes

Named customers6 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration13 records

AI capability12 records

Feature9 records

Partnerships

Four partnerships are on record, tiered core.

• SK pharmtecocoreStrategic or Co-development Partner · 7 May 2026Strategic partnership with SK pharmteco and NIH to advance gene therapy programs for rare inherited blood and metabolic disorders. Axle Informatics serves as the primary contractor while SK pharmteco acts as subcontractor providing viral vector manufacturing and analytical support. First program focuses on producing lentiviral vectors for ex vivo transduction of patients' CD34+ hematopoietic stem cells, moving toward clinical trials.
• National Institutes of Health (NIH)coreStrategic or Co-development PartnerLong-standing partnership as prime contractor on NIH SOAR ($3.6B) and multiple other NIH contract vehicles including NIAID PSTSS, NCATS STSS, and NHLBI ITAC. Supports NIH biomedical research programs through comprehensive research, technology, and healthcare solutions.
• National Center for Advancing Translational Sciences (NCATS)coreStrategic or Co-development PartnerDesigned, implemented, and currently maintains the Unified NCATS Auth (UNA) system - a cloud-based federation, authorization, and identity management service. Supports over 400,000 logins across 150+ applications with integrations across N3C, CTSA, SmartIRB, AWS, and CLAD.
• Rare Diseases Clinical Research Network (RDCRN) Data Management and Coordinating Center (DMCC)coreStrategic or Co-development PartnerPartnered with RDCRN DMCC to spearhead migration from on-premises architecture to cloud environment, enhancing collaboration and research process efficiency. Provides ongoing project management and strategic advice for rare disease research consortia members.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Broad incumbents

• Leidos: Major federal health IT and biomedical research contractor providing clinical informatics, data analytics, and lifecycle research support to NIH and other federal health agencies. Significantly larger than Axle but competes directly for NIH and federal health task orders where Axle is a prime.
• Booz Allen Hamilton: Large federal consulting prime with deep NIH and federal health IT practices across AI/ML, data science, and biomedical informatics. Competes for many of the same federal research and clinical informatics task orders as Axle.
• ICF International: Federal health and research consultancy with established NIH, HHS, and CDC workforces in analytics, program management, and digital transformation. Closely aligned with Axle's research-management and data-science offerings to federal health clients.
• Deloitte (Federal Health): Global professional services firm with a sizable federal health practice serving NIH, CMS, and HHS on AI/ML, cloud, and biomedical informatics. Overlaps with Axle on technology transformation and population health analytics.
• Maximus: Federal services prime with growing health and citizen services exposure, including clinical-IT and digital transformation engagements. Competes for many federal health-adjacent services task orders.
• SAIC: Large federal IT and engineering services prime with health IT and federal research customers. Competes for NIH-adjacent cloud, cybersecurity, and digital services task orders.
• ManTech (Constellation Federal Solutions): Federal IT services prime with deep federal health and intelligence customer footprint, including data analytics and cyber. Competes for NIH and federal health IT work alongside Axle and other mid-tier primes.

Direct peers

• DLH Holdings: Mid-sized federal contractor focused on health, science, and research programs for NIH, DoD, and federal civilian agencies. Comparable size, customer set, and biomedical/research services overlap, making it one of the closest direct comparables to Axle.
• Chenega Federal Solutions: Mid-tier federal contractor providing biomedical, clinical, and technology services to NIH and other federal health agencies. Operates in the same socioeconomic contracting space as a competitor on smaller task orders.
• Noblis: Nonprofit federal research and technology services firm serving HHS, NIH, and federal science agencies on data science, AI, and biomedical informatics. Closely comparable in mission focus and customer set to Axle.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/axle-informatics

Compliance5 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Funding overview

Funding rounds

Investors

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M&A

Investments

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Frequently asked questions about Axle Informatics