What ZeptoMetrix does

ZeptoMetrix is a Buffalo, New York-based manufacturer and supplier of quality control materials and analytical reference standards serving clinical diagnostic laboratories, environmental testing facilities, cannabis and hemp testing labs, pharmaceutical manufacturers, and food and agriculture testing facilities. Founded in 1997 and operating as a subsidiary of Antylia Scientific, the company organizes its offering into two main divisions. The Diagnostic division, anchored by the NATtrol sub-brand, provides ready-to-use molecular QC materials, antigen controls, immunoassay reagents, seroconversion panels drawn from over 160 unique donors, and microorganism reference cultures. The Analytical division supplies certified reference materials, reagents, and ISO 17043-accredited proficiency testing services through the Spex Certiprep, Chiron, and NSI Lab Solutions brands, covering PFAS, pesticides, heavy metals, cannabis potency, and other regulated analytes across environmental, food, pharmaceutical, and cannabis/hemp markets.

The company's technical core is the proprietary Phage-Like Particle (PLP) technology that encapsulates RNA within non-infectious particles, enabling quantitative molecular QC products such as the June 2025-launched NATtrol Influenza A H5N1 Quantitative Stock. ZeptoMetrix is ISO/IEC 17025, ISO 17034, and ISO 17043 accredited and is recognized as one of the top ten players in the molecular quality controls market, with QC products validated for compatibility across more than a dozen major molecular diagnostic platforms including BioFire FilmArray, Cepheid GeneXpert, Roche ePlex, Abbott ID NOW, and Hologic Panther Fusion.

ZeptoMetrix monetizes primarily through one-time catalog sales of QC materials and reference standards via a customer-login e-commerce storefront, supplemented by a regional distributor network and recurring revenue from scheduled proficiency testing programs. Pricing is quote-based and not publicly disclosed. The company pursues thought-leadership marketing through scientific publications, industry conferences, and the company-hosted Diagnostics Decoded podcast, targeting laboratory professionals and IVD diagnostic manufacturers globally.

Name

ZeptoMetrix

Legal name

ZeptoMetrix

Website

https://zeptometrix.com

Company type

Private

Founded year

1997

Operating status

Operating

Headcount range

101–250 employees

Short description

ZeptoMetrix manufactures and supplies molecular diagnostic quality controls and analytical certified reference materials for clinical, environmental, pharmaceutical, food, and cannabis testing laboratories worldwide, operating under Antylia Scientific.

Ownership category

akta.pro rank

Product category

Diagnostic Quality Controls and Analytical Reference Materials

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Quality Control, Calibrators, Standards & Proficiency Testing (IVD Consumables) (HLAHAAAL)

akta.pro secondary industries

Laboratory Quality & GLP/GCLP Compliance (HLAGAKAK), Proficiency Testing Programs & Schemes (Food PT Providers) (AFALAKAA), Matrix-Matched Standards & Spiking Materials (Food Contaminants/Residues) (AFALAKAI), Release Testing & Batch Certification (QC) (HLAGADAC)

Keywords

• Molecular quality controls
• Analytical reference materials
• Proficiency testing services
• Diagnostic assay development
• Microbiology reference standards

Headquarters

HQ city

Buffalo

HQ country

United States

HQ region

North America

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Diagnostic Quality Controls: Sale of quality control materials including molecular controls, antigen controls, serology panels, and microorganisms for IVD diagnostic assay development and laboratory QC.
2. Analytical Reference Materials: Sale of certified reference materials, standards, and reagents for analytical testing in environmental, pharmaceutical, food & agriculture, and cannabis & hemp markets.
3. Proficiency Testing Services: Accredited PT programs providing laboratory proficiency testing samples and evaluation services for regulatory compliance.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels4 records

Core offering

ZeptoMetrix manufactures and supplies quality control materials, analytical reference standards, certified reference materials, and proficiency testing programs for clinical diagnostic, environmental, pharmaceutical, food safety, and cannabis testing laboratories. The company sells ready-to-use molecular and antigen controls (NATtrol brand), seroconversion panels, microorganisms, PFAS and inorganic analytical standards, and ISO 17043-accredited proficiency testing under sub-brands including Spex Certiprep and Chiron. It also offers custom standard development and end-to-end assay development services for IVD manufacturers.

Product overview

ZeptoMetrix, a subsidiary of Antylia Scientific, is a provider of molecular diagnostic quality controls and analytical reference materials for clinical laboratories, environmental testing facilities, and research institutions. The product portfolio is organized into two main divisions: Diagnostic Products and Analytical Reference Materials. The Diagnostic division centers on the NATtrol brand of quality control materials, supported by proprietary Phage-Like Particle (PLP) technology that encapsulates RNA for enhanced molecular testing accuracy. Key product lines include Molecular Quality Controls (covering respiratory, women's health/STI, gastrointestinal, healthcare-associated infections, BCID, and critical infectious disease panels), Antigen Quality Controls, Immunoassay Solutions (ELISA kits, Western blot kits, reagents, and antibodies), Serology Products (seroconversion panels for HIV, HBV, HCV, and Zika; longitudinal panels; and verification/validation panels), Microorganisms (virus, bacteria, fungi, parasites, bacteriophage, and heat-inactivated culture fluids), and Oncology Products (cfDNA controls and DNA-depleted plasma). The Analytical division provides the broadest portfolio of certified reference materials, proficiency testing, reagents, and microbiology products through sub-brands including Spex Certiprep and Chiron, covering environmental testing (PFAS, microplastics, pesticides, PCBs, wastewater, drinking water), food and agriculture, cannabis and hemp, pharmaceutical, toxicology, and industrial applications. A proprietary Phage-Like Particles (PLP) technology platform underpins several molecular diagnostic products, enabling encapsulated RNA for comprehensive laboratory validation.

Differentiator

Problem solved

Functional benefit

Brands

• NATtrol: Diagnostic quality control product brand for molecular diagnostics, including molecular swabs, respiratory panels, women's health and STI controls, gastrointestinal controls, healthcare associated infection controls, blood culture controls, and critical infectious disease panels.
• NATtrol (with trademark)
• Spex CertiPrep
• Chiron
• Snap-Stick Cultures
• Claritas PPT
• PT Datalink

Products and services

• Molecular Quality Controls Ready-to-use molecular QC materials and panels for routine molecular diagnostic testing, covering respiratory infections, women's health/STI, gastrointestinal pathogens, healthcare-associated infections, blood culture identification (BCID), and critical infectious disease panels. Used by clinical and diagnostic laboratories for assay validation and routine QC.
• Antigen Quality Controls Quality control products designed for antigen-based diagnostic testing workflows, including respiratory antigen QC materials for clinical laboratories.
• Immunoassay Solutions ELISA kits, Western blot kits, reagents, polyclonal antibodies, and monoclonal antibodies for immunoassay development and routine testing, targeted at IVD developers and diagnostic laboratories.
• Serology Products Seroconversion panels built from over 160 unique donors with single-patient specimens serially collected through disease progression for HIV, HBV, HCV, and Zika; also includes longitudinal panels and verification/validation panels for assay developers and clinical labs.
• Microorganisms Heat-inactivated culture fluids (CFHI), virus, bacteria, fungi, parasite, and bacteriophage products for diagnostic, research, and quality control use.
• Oncology Products cfDNA controls and DNA-depleted plasma designed for oncology diagnostic testing and assay validation workflows.
• NATtrol Product Line Proprietary sub-brand of molecular QC materials including whole-organism, non-infectious, ambient-temperature-stable (up to 30°C) molecular swabs, respiratory controls, BCID panels, STI controls, and influenza/COVID/RSV controls.
• Analytical Reference Materials Broad portfolio of certified reference materials and standards for environmental (PFAS, microplastics, organotins, pesticides, PCBs, wastewater, drinking water, soil/UST), food and agriculture, cannabis and hemp, pharmaceutical, toxicology, industrial, and petroleum markets.
• PFAS Certified Reference Materials PFAS CRMs and PFAS mixes formulated to ultra-pure standards to reduce isomer interference and boost accuracy, covering EPA methods 533, 537.1, 1633, and NPDWR.
• Proficiency Testing Programs ISO 17043-accredited scheduled proficiency testing and PT Express programs for environmental, food science, and cannabis/hemp laboratories, covering wastewater, drinking water, microbiology, soil, food, and cannabis testing matrices.
• Reagents Analytical reagents including acids and bases, buffers, carbon black, solutions, solvents, salts and solids, and mobile phase modifiers for laboratory workflows.
• Microbiology Products Environmental, pharmaceutical, and food/agriculture microbiology standards including wastewater standards, multi-organism controls for Petrifilm, QC knowns, Snap-Stick cultures, Unit Dose microbiological controls, and rehydration fluid.
• Spex Certiprep Analytical Standards Sub-brand offering ICP, ICP-MS, NMR, HPLC, IC, LC/MS, GC/MS, and GC analytical standards, including Claritas PPT ICP-MS multi-element and single/multi-element standards.
• Custom Standards Custom-developed reference material standards produced to meet specific customer analytical testing requirements.
• Assay Development Services End-to-end partnership service delivering high-quality controls and immunoassay solutions for IVD diagnostic assays, from ready-to-use controls through customized assay support, intended to streamline development and elevate diagnostic accuracy for IVD manufacturers.
• NATtrol Influenza A H5N1 Quantitative Stock Quantitative molecular QC stock for avian influenza H5N1 testing validation, leveraging phage-like particle (PLP) encapsulated RNA technology with three H5N1 gene segments at 1,000,000 gene copies/mL each, verified by digital PCR, in a ready-to-use 1 mL format. Targeted at clinical and public health laboratories validating H5N1 molecular assays.

Named customers3 records

Segments5 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration18 records

Feature4 records

Partnerships

Five partnerships are on record, tiered internal.

• Chiron (brand within Antylia Scientific)internalTechnology or IntegrationChiron brand offers PFAS certified reference materials and specialty standards, integrated under the ZeptoMetrix portfolio.
• Spex Certiprep (brand within Antylia Scientific)internalTechnology or IntegrationSpex Certiprep provides ICP and ICP-MS standards, HPLC standards, and other analytical reference materials sold through the ZeptoMetrix platform.
• NSI Lab Solutions (brand within Antylia Scientific)internalTechnology or IntegrationNSI provides proficiency testing services and quality control solutions for environmental, food, and cannabis testing markets.
• Environmental Express (brand within Antylia Scientific)internalTechnology or IntegrationEnvironmental Express brand offers environmental testing products, available through the ZeptoMetrix website.
• Cole-Parmer (brand within Antylia Scientific)internalTechnology or IntegrationCole-Parmer provides laboratory equipment and supplies, cross-promoted through the ZeptoMetrix platform.

Scale indicators3 records

Recent moves5 records

Expansion highlights5 records

Direct peers

• Bio-Rad Laboratories: Bio-Rad is a leading global supplier of molecular diagnostic quality controls, reference materials, and proficiency testing through its Life Science and Clinical Diagnostics segments. It directly competes with ZeptoMetrix in NATtrol-equivalent molecular QC and is one of ZeptoMetrix's named co-competitors in the molecular QC market.
• Microbiologics: Microbiologics supplies biological reference materials, including inactivated microorganisms and QC controls, serving clinical, environmental, and food-safety labs. It is a directly comparable peer to ZeptoMetrix's microorganism and microbiology QC lines and is a named co-competitor in the molecular QC market.
• LGC Group: LGC is a major global producer of reference materials, certified reference standards, and proficiency testing (via LGC AXIO Proficiency Testing). It directly overlaps with ZeptoMetrix's Spex Certiprep-style analytical reference materials and NSI-equivalent PT programs, and is a named co-competitor.
• Qnostics: Qnostics specializes in molecular quality controls for infectious disease testing, including respiratory, sexually transmitted infections, and blood-borne viruses. It directly competes with ZeptoMetrix's NATtrol molecular QC portfolio and is a named co-competitor in the molecular QC market.
• Randox Laboratories: Randox manufactures third-party diagnostic quality controls (Acusera), reference materials, and reagents used in clinical and molecular labs. It is a directly comparable peer to ZeptoMetrix's diagnostic QC and serology panels, and is a named co-competitor in the molecular QC market.
• ATCC: ATCC is a global biological resource center providing authenticated microorganisms, cell lines, and reference materials for clinical, environmental, and research applications. It directly competes with ZeptoMetrix's microorganism product line and serves overlapping clinical and analytical testing customers.
• Cerilliant (Merck): Cerilliant, now part of Merck, specializes in certified reference standards for clinical and forensic toxicology, pharmaceuticals, and cannabis testing. It directly overlaps with ZeptoMetrix's pharmaceutical and cannabis/hemp reference materials lines and serves a comparable analytical-testing customer base.

Broad incumbents

• Thermo Fisher Scientific: Thermo Fisher is the largest life-sciences tools provider, offering molecular diagnostic QCs, reference materials (via its acquired standards business), and proficiency testing as part of a much broader portfolio. It is a named co-competitor to ZeptoMetrix and bundles QCs with instruments and reagents at scale.
• Merck (Sigma-Aldrich) Reference Materials: Merck's Sigma-Aldrich and Supelco brands supply a comprehensive catalog of analytical reference materials, certified standards, and reagents for chromatography and spectroscopy. It overlaps with ZeptoMetrix's Spex Certiprep/Chiron analytical reference materials business across environmental, pharmaceutical, and food testing.
• bioMérieux: bioMérieux is a global in vitro diagnostics and microbiology company with industrial QC applications (BioBall, TEMPO) for pharmaceutical and food microbiology. It competes with parts of ZeptoMetrix's microbiology QC and is a named co-competitor in the broader molecular QC market.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/zeptometrixcorporation
• LinkedInlinkedin.com/company/zeptometrix

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about ZeptoMetrix