IROA Technologies
IROA Technologies is a private Virginia-based metabolomics tools company that sells isotope-labeled internal standards, ten metabolite standard libraries, and cloud-based analysis software (ClusterFinder, Dual MSTUS) to academic, pharmaceutical, biotech, and clinical research laboratories for quantitative LC-MS metabolomics.
- Company typePrivate
- Founded2010
- HeadquartersNellysford, United States
- Headcount1–10
- GTM typeB2B
- OfferingSoftware
What IROA Technologies does
IROA Technologies is a privately-held metabolomics tools company founded in 2010 by Chris Beecher and Felice A. de Jong, headquartered in Nellysford, Virginia. The company develops and commercializes Isotope Ratio Outlier Analysis (IROA), a quantitative metabolomics methodology built around proprietary 5% and 95% U-13C labeled internal standards that create mathematically calculable isotopic envelopes. These standards are produced via labeled yeast extract supplied through a strategic partnership with Cambridge Isotope Technologies.
The company's product portfolio spans three integrated layers: (1) ten metabolite standard libraries covering primary metabolism, amino acids/peptides, bile acids, fatty acids, microbiome, organic acids, oncometabolites, phytochemicals, and polyphenols, sold in 96-well plate format at prices ranging from $1,400 to $18,700; (2) the TruQuant Workflow Kit and IROA Internal Standard Kit, priced at $200 per kit for 90 samples, which deliver ion suppression correction and identify 400-600 metabolites per analysis; and (3) software tools including ClusterFinder (cloud-based peak detection, suppression correction, and metabolite identification), Dual MSTUS (normalization), and MLSDiscovery (spectral library building). The company holds 12+ patents and 75+ peer-reviewed publications supporting its methodology.
IROA generates revenue primarily through one-time product sales of metabolite libraries and internal standard kits, supplemented by subscription-based access to its ClusterFinder cloud software. It sells globally via direct website sales, field sales outreach to academic, pharmaceutical, biotech, and core facility customers, and self-serve software downloads. Key customers include MD Anderson Cancer Center, the NIH West Coast Metabolomics Center at UC Davis, NCATS, University of Florida SECIM, Albert Einstein College of Medicine, and DuPont Pioneer. The company is ISO 9001:2015 certified and was founded on prior metabolomics expertise from the founders' tenures at Metabolon and Paradigm Genetics.
IROA Technologies firmographics
Firmographics- Name
- IROA Technologies
- Legal name
- IROA Technologies LLC
- Website
- https://iroatech.com
- Company type
- Private
- Founded year
- 2010
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- IROA Technologies is a private Virginia-based metabolomics tools company that sells isotope-labeled internal standards, ten metabolite standard libraries, and cloud-based analysis software (ClusterFinder, Dual MSTUS) to academic, pharmaceutical, biotech, and clinical research laboratories for quantitative LC-MS metabolomics.
- Ownership category
- akta.pro rank
IROA Technologies industry classification
Industry- Product category
- Quantitative Metabolomics Research Tools
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), In-Vitro Diagnostic Substance Manufacturing (325413), Scientific Research and Development Services (5417)
- SIC
- Laboratory Analytical Instruments (3826)
- akta.pro primary industry
- AI/ML Platforms for Drug Discovery & Experiment Optimization (HLAGAJAO)
- akta.pro secondary industries
- High-Throughput Screening & Assay Platforms (HTS/HCS, phenotypic screening) (HLAAAIAA), Biomarker Discovery & Validation (omics, assay feasibility, clinical validation) (HLAAAMAA)
Keywords
Where IROA Technologies is headquartered
LocationHeadquarters
- HQ city
- Nellysford
- HQ country
- United States
- HQ region
- North America
Offices3 records
Markets served
IROA Technologies business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales, Supply Chain, Infrastructure
Revenue model
- Metabolite Library Sales: Sale of authenticated metabolite standard libraries in 96-well plate format. Libraries include MSMLS (600 compounds, $6,050), LSMLS (600 compounds, $18,700), and specialized libraries for amino acids, bile acids, fatty acids, organic acids, microbiome, phytochemicals, polyphenols, and oncometabolites ranging from $1,400 to $5,042.
- Internal Standard Kits: Sale of IROA Internal Standard Kit (95% U-13C labeled yeast extract) and TruQuant Workflow Kit. Identifies and quantifies 400-600 metabolites. Priced at $200 for 90 samples.
- ClusterFinder Software: Cloud-based software for metabolomics data analysis. Available via download with login access. Supports automated compound identification, suppression correction, and normalization workflows.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Pay-as-you-go | Amino Acid/Peptide Library (AAPMLS) - 168 compounds |
| One time/ perpetual license | Pay-as-you-go | Bile Acid/Carnitine/Sterol Library (BACSMLS) - 96 compounds |
| One time/ perpetual license | Pay-as-you-go | Fatty Acid Library (FAMLS) - 96 compounds |
| One time/ perpetual license | Pay-as-you-go | Large Scale Library (LSMLS) - 600 compounds, 1mg each |
| One time/ perpetual license | Pay-as-you-go | Mass Spec Library (MSMLS) - 600 compounds, 5µg each |
| One time/ perpetual license | Pay-as-you-go | Microbiome Library (GUTMLS) - 185 compounds |
| One time/ perpetual license | Pay-as-you-go | Oncometabolite Library (ONCOMLS) - 96 compounds |
| One time/ perpetual license | Pay-as-you-go | Organic Acid Library (OAMLS) - 96 compounds |
| One time/ perpetual license | Pay-as-you-go | Phytochemical Library (PHYTOMLS) - 364 compounds |
| One time/ perpetual license | Pay-as-you-go | Polyphenol Library (PPMLS) - 80 compounds |
| Unit Pricing | Pay-as-you-go | IROA Internal Standard Kit - 90 samples capacity |
| One time/ perpetual license | Pay-as-you-go | Unlabeled Mammalian Cell Media |
Go-to-market motion1 record
Distribution channels3 records
Marketing channels6 records
IROA Technologies product offering
Product offeringCore offering
IROA Technologies develops and sells an integrated quantitative metabolomics platform consisting of three components: (1) authenticated metabolite standard libraries in 96-well format covering primary and specialized biochemical classes; (2) isotope-labeled internal standard kits, notably the IROA Internal Standard Kit and TruQuant Workflow Kit using 95% and 5% U-13C labeled yeast extract; and (3) proprietary data analysis software including ClusterFinder, MLSDiscovery, and Dual MSTUS that together deliver suppression-corrected, normalized, reproducible metabolite identification and quantitation.
Product overview
IROA Technologies offers a unified metabolomics platform comprising three integrated components: (1) Metabolite Libraries including MSMLS (600 compounds), LSMLS, FAMLS, AAPMLS, BACSMLS, GUTMLS, OAMLS, ONCOMLS, PHYTOMLS, PPMLS, and Custom Libraries for authentic compound identification; (2) TruQuant Workflow including IROA Internal Standard Kit with 95% U-13C labeled yeast extract for ion suppression correction and normalization; and (3) Software Solutions including ClusterFinder for automated data analysis, Dual MSTUS for sample normalization, and MLSDiscovery for library creation. All components are designed to work together within the IROA ecosystem to deliver standardized workflows, suppression-corrected quantitative analysis, and confident metabolite identification.
Differentiator
Problem solved
Functional benefit
Brands
- TruQuant: Semi-targeted QC workflow for accurate metabolomics using isotope-labeled internal standards and ClusterFinder software.
- ClusterFinder
- MLSDiscovery
- CloudCluster
Products and services
- MSMLS (Mass Spectrometry Metabolite Library of Standards)
Quantifiable outcome
- RSD reduced to 1% compared to raw data through suppression correction and Dual MSTUS normalization (Ghosh et al., 2025)
- +3 more outcomes
Companies that use IROA Technologies
Customer profileNamed customers9 records
Segments4 records
Ideal customer profiles3 records
IROA Technologies technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability4 records
Feature7 records
IROA Technologies partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- Cambridge Isotope Technologies, Inc.coreCambridge Isotope Technologies specially manufactures 5% and 95% U-13C labeled glucose compounds for IROA Technologies. These labeled compounds are essential raw materials for producing IROA's internally labeled yeast extract and internal standard products.
Scale indicators8 records
Recent moves6 records
Expansion highlights6 records
IROA Technologies competitors and assessment
Company assessmentDirect peers
- Metabolon: Direct peer in metabolomics services and quantitative analysis platforms. Founded by Chris Beecher (IROA's current CSO) and Richard Higashi; competes in the same biomarker discovery / quantitative metabolomics space as IROA, though with a service-based rather than product-based model.
- Biocrates Life Sciences: Direct competitor offering standardized metabolomics kits (e.g., MxP Quant 500) and analysis software for targeted metabolomics, with overlapping customer base in pharma and academic research. Comparable in product mix (kits + software) and workflow standardization positioning.
Broad incumbents
- Thermo Fisher Scientific: Broad incumbent owning the leading LC-MS instruments (Orbitrap/Q Exactive) on which IROA's workflow runs, plus Compound Discoverer software that overlaps with ClusterFinder. IROA's application notes explicitly target Thermo instruments, making this both a partner and competitor.
- Agilent Technologies: Broad incumbent providing mass spectrometry instruments and MassHunter/Unknowns Analysis software used in metabolomics. Gus Salem (IROA board member) is a former VP/GM of Agilent's Biological Systems Division, signaling tight ecosystem overlap.
- Waters Corporation: Broad incumbent in LC-MS (Xevo G2-XS QTof, ACQUITY UPLC) with MassLynx/Progenesis QI metabolomics software. Competes broadly for metabolomics workflow budgets and could replicate IROA's suppression correction features in-house.
- Bruker: Broad incumbent offering timsTOF and other MS platforms plus MetaboScape software for metabolomics. IROA application notes target Bruker instruments, indicating same-customer/competing-tool dynamic as with Thermo and Agilent.
- SCIEX (Danaher): Broad incumbent in mass spectrometry (TripleTOF, QTRAP) with SCIEX OS software. IROA application notes explicitly cover SCIEX workflows, so the company overlaps with IROA on customer targeting.
Others
- Cambridge Isotope Laboratories: IROA's sole disclosed raw-material supplier for 5% and 95% U-13C labeled glucose, and the broader market leader in stable isotope-labeled compounds. Also a partial competitor in isotope-labeled standards used for metabolomics research.
Emerging players
- Cayman Chemical: Specialty reagent supplier offering metabolite reference standards, screening libraries, and biochemical toolkits overlapping with IROA's library business. Targets similar academic and pharma research customers.
- HighChem (mzCloud): Developer of mzCloud mass spectral library and Compound Discovery software used in metabolomics. Emerging player with partial functional overlap to ClusterFinder (peak detection, library-based ID, suppression correction).
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
IROA Technologies social profiles
Digital presenceIROA Technologies compliance and trust
Trust signalCompliance1 record
IROA Technologies financial estimates
Financial estimateRevenue estimate
Valuation estimate
IROA Technologies leadership team
Management profileNumber of profiles
Profiles10 records
IROA Technologies funding detail
Funding detailFunding overview
Funding rounds2 records
Investors1 record
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
IROA Technologies M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about IROA Technologies
What does IROA Technologies do?
IROA Technologies develops and sells an integrated quantitative metabolomics platform consisting of three components: (1) authenticated metabolite standard libraries in 96-well format covering primary and specialized biochemical classes; (2) isotope-labeled internal standard kits, notably the IROA Internal Standard Kit and TruQuant Workflow Kit using 95% and 5% U-13C labeled yeast extract; and (3) proprietary data analysis software including ClusterFinder, MLSDiscovery, and Dual MSTUS that together deliver suppression-corrected, normalized, reproducible metabolite identification and quantitation.
Is IROA Technologies a public or private company?
IROA Technologies is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was IROA Technologies founded?
IROA Technologies was founded in 2010. It employs 1 to 10 people.
Where is IROA Technologies based?
IROA Technologies is headquartered in Nellysford, United States, in the North America region.
How does IROA Technologies make money?
Three revenue lines are on record. Metabolite Library Sales are the primary driver. The others are internal Standard Kits and clusterFinder Software.
Who are IROA Technologies's main competitors?
Direct peers on record are Metabolon and Biocrates Life Sciences. Broad incumbents are Thermo Fisher Scientific, Agilent Technologies, Waters Corporation, Bruker and SCIEX (Danaher). Cambridge Isotope Laboratories is listed as an others. Emerging players are Cayman Chemical and HighChem (mzCloud).
Does IROA Technologies have an API?
No public API is recorded for IROA Technologies.
What industry is IROA Technologies in?
IROA Technologies's product category is Quantitative Metabolomics Research Tools. Its primary akta.pro industry code is HLAGAJAO, AI/ML Platforms for Drug Discovery & Experiment Optimization, with a secondary code of HLAAAIAA, High-Throughput Screening & Assay Platforms (HTS/HCS, phenotypic screening). Its NAICS code is 541714 and its SIC code is 3826.