What Egnite does

Egnite is a digital health company that provides an AI-driven cardiovascular intelligence platform to U.S. health systems and life sciences organizations. Its flagship product, the CardioCare Platform, integrates electronic health record and echocardiographic data, processing more than 3,000 data points per patient to identify individuals with underdiagnosed or undertreated cardiovascular conditions, including structural heart disease, heart failure, and atrial fibrillation, and to support guideline-directed medical therapy adherence and clinical trial enrollment. The platform is underpinned by proprietary natural language processing algorithms (including a patented mitral regurgitation classification method achieving 97.3%-99.0% accuracy) and fine-tuned large language models trained on de-identified clinical data, with deployment across more than 600 healthcare facilities.

The company sells primarily through direct enterprise field sales to health systems under multi-year contracts and extends its offering to medical device, pharmaceutical, and biotech sponsors via the CardioCare Research Suite, the Therapy Accelerator, and collaborative research services. The egnite Registry, covering 14M+ patients across 45+ health systems and 800+ facilities, is licensed for research use within a Databricks environment and serves as both a data flywheel and a standalone subscription product. Founded in 2016 as a spin-off from Edwards Lifesciences, egnite is headquartered in Aliso Viejo, California, with 101-250 employees and no public funding or revenue figures disclosed.

Name

Egnite

Legal name

egnite, Inc.

Website

https://egnitehealth.com

Company type

Private

Founded year

2016

Operating status

Operating

Headcount range

51–100 employees

Short description

Egnite is a digital health company offering an AI-powered cardiovascular intelligence platform that helps U.S. health systems and life sciences organizations identify and manage patients with untreated cardiovascular disease. Its CardioCare platform and Registry serve 75+ health systems across 800+ facilities.

Ownership category

akta.pro rank

Product category

Cardiovascular Analytics Software

NAICS

Other Scientific and Technical Consulting Services (54169)

SIC

Services-Health Services (8000)

akta.pro primary industry

Risk Stratification, Early Warning Scores & Predictive Analytics (HLACAGAE)

Keywords

• Cardiovascular analytics platform
• Clinical trial recruitment
• Patient identification AI
• Real-world evidence data
• Digital health platform

Headquarters

HQ city

Aliso Viejo

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. CardioCare Platform Subscription: SaaS platform subscription model providing AI-powered cardiovascular patient identification and management tools to health systems. Pricing likely enterprise-level with multi-year contracts based on facility count and data scope.
2. egnite Registry Data Access: Subscription access to de-identified longitudinal clinical data delivered within Databricks environment for data scientists and biostatisticians. Month-to-month access available. Also offers collaborative research services for strategists requiring curated insights.
3. Clinical Trial Patient Identification: CardioCare Research Suite enables health systems to identify patients eligible for clinical trials across participating health systems, generating value for both health system customers and life sciences sponsors.
4. Life Sciences Partnerships: Partnerships with life sciences companies for therapy acceleration and clinical trial support services. Includes real-world data analysis, patient identification for trials, and research collaboration.

Go-to-market motion2 records

Distribution channels1 record

Marketing channels8 records

Core offering

Egnite sells the CardioCare Platform, a SaaS-based AI-driven cardiovascular intelligence platform that integrates electronic health record (EHR) and echocardiographic data to help U.S. health systems identify and manage patients with untreated cardiovascular disease across valve disease, heart failure, atrial fibrillation, and clinical trials. The platform is extended by the CardioCare Research Suite (for clinical trial patient identification, including Lp(a) capability), the egnite Registry (a longitudinal, de-identified real-world cardiovascular dataset spanning 14M+ patients), and life sciences offerings including the egnite Therapy Accelerator and egnite Research collaborative services.

Product overview

Egnite offers the CardioCare Platform as its core product—a digital health platform leveraging AI-driven algorithms and big data analytics to help health systems identify and manage patients with untreated cardiovascular disease. The platform integrates electronic health records and echocardiographic data across valve disease, heart failure, and atrial fibrillation. The CardioCare Research Suite extends the platform with clinical trial patient identification capabilities, including a new Lp(a) Identification module. Egnite's egnite Registry provides access to longitudinal real-world clinical data from over 14 million patients across 45+ health systems. For life sciences organizations, Egnite offers the Therapy Accelerator for trial enrollment and patient activation, alongside collaborative research services across major cardiovascular conditions. The company is headquartered in Aliso Viejo, California.

Differentiator

Problem solved

Functional benefit

Brands

• CardioCare: The leading digital health platform for progressive cardiovascular centers, providing AI-powered patient identification and management solutions across valve disease, heart failure, atrial fibrillation, and clinical trials.

Products and services

• CardioCare Platform AI-driven digital health platform that integrates EHR and echocardiographic data to help U.S. health systems identify and manage patients with untreated cardiovascular disease across valve disease, heart failure, atrial fibrillation, and clinical trial eligibility.
• CardioCare Research Suite Module within the CardioCare Platform that enables hospitals to automatically identify patients eligible for cardiovascular clinical trials across participating health systems, including Lp(a) patient identification.
• egnite Registry Subscription-based longitudinal real-world clinical dataset providing de-identified cardiovascular data from 14M+ patients across 45+ health systems and 800+ facilities, delivered within a Databricks environment for advanced research.
• egnite Therapy Accelerator Life sciences solution designed to drive patient activation for existing cardiovascular therapies and accelerate clinical trial enrollment, using AI and advanced data processing to pre-screen eligible patients and improve enrollment efficiency by up to 55%.
• egnite Research Collaborative research service enabling life sciences organizations to answer contemporary questions in cardiovascular disease across heart failure, atrial fibrillation, mitral regurgitation, tricuspid disease, and aortic stenosis through partnership with Egnite's real-world data ecosystem.

Quantifiable outcome

• Mean 25% increase in SHD procedures at CardioCare sites
• +6 more outcomes

Named customers8 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability9 records

Feature5 records

Partnerships

Five partnerships are on record, tiered core.

• Boston ScientificcoreStrategic or Co-development PartnerBoston Scientific logo appears on egnite's Life Sciences page as a partner organization. The partnership likely involves collaboration on cardiovascular patient identification and clinical trial support for Boston Scientific's structural heart and other cardiovascular therapies.
• JenaValvecoreStrategic or Co-development PartnerJenaValve partnered with egnite and The Christ Health Network to deploy AI tools such as egnite's Trial Accelerator for expedited identification of eligible candidates for the CORCINCH-HF trial evaluating JenaValve's AccuCinch System for heart failure patients.
• Ancora HeartcoreStrategic or Co-development PartnerAncora Heart partnered with egnite and The Christ Health Network to use egnite's Trial Accelerator to expedite identification of eligible candidates for the CORCINCH-HF trial. Collaboration aims to improve heart failure patient outcomes through minimally invasive treatment options.
• The Christ Hospital Health NetworkcoreStrategic or Co-development PartnerClinical partnership where The Christ Hospital Health Network serves as a key reference customer and research collaborator. Dr. Dean Kereiakes, President of The Christ Hospital Heart and Vascular Institute, provides testimonials and the network achieves 4x ROI using CardioCare.
• 45+ Health Systems (Registry Contributors)coreStrategic or Co-development PartnerHealth systems contributing de-identified data to the egnite Registry, enabling the company's real-world evidence capabilities. These partners include major U.S. cardiovascular programs that process patient data through egnite's NLP algorithms.

Scale indicators11 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Cleerly: Cleerly applies AI to coronary CT angiography for cardiovascular plaque analysis and risk stratification, directly competing with egnite in AI-powered cardiovascular patient identification for health systems and life sciences partners.
• Caption Health (GE HealthCare): Caption Health (acquired by GE HealthCare) builds AI guidance for cardiac ultrasound acquisition and interpretation, overlapping with egnite's echocardiogram-driven NLP/LLM workflows for cardiovascular disease identification.
• Tempus AI: Tempus AI is an AI-driven precision medicine platform offering real-world evidence, clinical trial matching, and data analytics to health systems and life sciences, directly comparable to egnite's AI + registry + trial patient identification model.
• Health Catalyst: Health Catalyst is a healthcare analytics and outcomes-improvement platform sold enterprise-wide to U.S. health systems, comparable to egnite's CardioCare enterprise SaaS model and population-health analytics layer.
• Arcadia: Arcadia provides a healthcare data platform for value-based care performance, population health, and clinical analytics to provider organizations, competing for the same health-system enterprise analytics budget as egnite.
• Komodo Health: Komodo Health operates a large healthcare data and analytics platform with real-world evidence and patient-finding capabilities for life sciences, directly overlapping with egnite's Registry, Research Suite, and Trial Accelerator offerings.

Emerging players

• ConcertAI: ConcertAI is an AI + real-world evidence company focused primarily on oncology, with comparable architecture to egnite for clinical trial patient identification and provider-facing analytics, indicating a path for egnite to replicate the model in additional specialties.
• Syapse: Syapse partners with health systems to apply real-world data and AI to oncology care delivery and research, sharing egnite's enterprise health-system + life-sciences RWE business model and tech stack orientation.

Broad incumbents

• Edwards Lifesciences: Edwards Lifesciences is the global leader in structural heart and critical care technologies and the originator of the CardioCare program that spun out into egnite; it remains a relevant incumbent with deep clinical relationships and overlapping cardiovascular AI initiatives.
• Optum (UnitedHealth Group): Optum is the largest U.S. healthcare data, analytics, and care services franchise and competes broadly with egnite through its clinical analytics, value-based care, and life-sciences RWE offerings aimed at health systems and payers.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/egnitehealth
• YouTubeyoutube.com/channel/UCGcjYnmvIOeaIwSij9HSk6Q
• LinkedInlinkedin.com/company/egnite-health

Revenue estimate

Valuation estimate

Number of profiles

Profiles11 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Egnite