Siteman Cancer Center

What Siteman Cancer Center does

Siteman Cancer Center is an NCI-designated Comprehensive Cancer Center operating as a nonprofit partnership between Barnes-Jewish Hospital and Washington University School of Medicine (WashU Medicine), headquartered at the Washington University Medical Campus in St. Louis, Missouri. Established in 1999 through a $35 million gift from Alvin and Ruth Siteman, the center provides comprehensive cancer treatment (medical therapy, radiation oncology including pencil-beam proton therapy, surgery, immunotherapy and CAR-T cell therapy, genetic counseling, and imaging), runs more than 700 therapeutic clinical trials with 500+ actively accepting patients, and holds over $180 million annually in NCI and NIH research grants, including SPORE grants in pancreatic, leukemia, and endometrial cancers. It serves 75,000 patients a year (12,000 newly diagnosed) through its main campus and six outpatient facilities across the St. Louis metropolitan area and southern Illinois, supplemented by the Siteman Cancer Network affiliations with regional medical centers.

The center derives revenue from patient care services (insurance, Medicare, and Medicaid reimbursement across all cancer types), federally sponsored research grants (NCI, NIH), and philanthropy through The Foundation for Barnes-Jewish Hospital. Its go-to-market combines multidisciplinary physician teams delivered through academic medical center channels, regional satellite facilities, a network affiliate model, and active community outreach and screening programs. Go-to-market assets include the award-winning 'This is Cancer' podcast, 'Learning with National Leaders' educational webinar series, and a broad social media presence, supported by community outreach such as mammography vans and the American Cancer Society Road To Recovery partnership.

Siteman's technology stack includes proprietary AI applications (machine-learning–augmented OCT imaging for endometrial cancer detection at 94% sensitivity/87% specificity, and an AI breast cancer risk prediction tool), breast cancer vaccines in clinical trials, GMP cell-therapy manufacturing capabilities, and a 657,250-square-foot Gary C. Werths Building opened in 2024 that consolidates multidisciplinary cancer care into a single-visit treatment model. The center is the only NCI-designated Comprehensive Cancer Center and the only NCCN member in Missouri and southern Illinois, has earned three consecutive NCI 'Exceptional' ratings (2015, 2020, 2023), and is staffed by 600+ WashU Medicine research scientists and physicians.

Name

Siteman Cancer Center

Legal name

Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and WashU Medicine

Website

https://siteman.wustl.edu

Company type

Private

Founded year

1999

Operating status

Operating

Headcount range

5,001–10,000 employees

Short description

Siteman Cancer Center is an NCI-designated Comprehensive Cancer Center and nonprofit partnership between Barnes-Jewish Hospital and WashU Medicine in St. Louis, delivering multidisciplinary cancer treatment, 700+ clinical trials, and prevention services to 75,000 patients annually across Missouri and southern Illinois.

Ownership category

akta.pro rank

Product category

Cancer Treatment Services

NAICS

Specialty (except Psychiatric and Substance Abuse) Hospitals (622310), Offices of Physicians (62111), Ambulatory Health Care Services (621), Diagnostic Imaging Centers (621512)

SIC

Services-Health Services (8000), Services-Specialty Outpatient Facilities, Nec (8093), Services-Commercial Physical & Biological Research (8731), Services-Offices & Clinics Of Doctors Of Medicine (8011)

akta.pro primary industry

Oncology & Cancer Specialty Hospitals (HLAFAHAC)

akta.pro secondary industries

Medical Oncology (HLAKAFAB), Radiation Oncology (HLAKAFAC), Gynecologic Oncology & Women’s Cancer Centers (HLAFAJAK), Neuro-Oncology (HLAKAFAH), Nuclear Medicine Clinical Services & Therapy Centers (HLAIAGAI)

Keywords

• Cancer treatment services
• Radiation oncology
• Oncology clinical trials
• Cancer research programs
• Cancer prevention screening

Headquarters

HQ city

St Louis

HQ country

United States

HQ region

North America

Offices7 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Infrastructure, Technology or R&D, Marketing or Sales, Supply Chain

Revenue model

1. Patient Care Services: Direct patient care services including treatment, diagnostics, and clinical services across multiple cancer types and satellite locations.
2. Research Grants and Funding: Scientists and physicians hold more than $180 million annually in basic and clinical oncology research grants from NCI, NIH, and other funding bodies. Includes SPORE grants for pancreatic, endometrial, and leukemia research.
3. Clinical Trials: Patients have access to 700 therapeutic clinical trials, with more than 500 clinical trials accepting new participants.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels5 records

Core offering

Siteman Cancer Center provides comprehensive cancer diagnosis, treatment, prevention, and survivorship services through an NCI-designated Comprehensive Cancer Center. Its core offerings span medical therapy, radiation oncology (including proton beam therapy), surgical oncology, immunotherapy (including CAR-T), clinical trials (700+ available), cancer imaging, pathology, genetic counseling, and pediatric oncology. Care is delivered by 600+ WashU Medicine physicians and research scientists across a main campus and six outpatient locations in the St. Louis metro area and southern Illinois.

Product overview

Siteman Cancer Center is a comprehensive cancer center offering a unified platform of treatment, research, and prevention services. The core offerings include multidisciplinary cancer treatment (medical therapy, radiation, surgery, immunotherapy), access to over 500 clinical trials, and specialized programs for specific cancer types. The center operates from its main campus including the new Gary C. Werths Building and S. Lee Kling Proton Therapy Center, with satellite facilities throughout the St. Louis metro area and Illinois. Supporting services include the This is Cancer podcast, Learning with National Leaders educational series, survivorship program, psychology services, cardio-oncology, and the Siteman Cancer Network affiliations. The center leverages AI-assisted imaging technologies including OCT for endometrial cancer detection and predictive analytics tools for breast cancer risk assessment.

Differentiator

Problem solved

Functional benefit

Brands

• Brain Tumor Center: Multidisciplinary center providing leading-edge, patient-centric care for brain tumor patients while developing transformative basic, translational and clinical research to develop new therapies and improve patient outcomes.
• Head & Neck Tumor Center
• WashU Medicine Cardio-Oncology Center of Excellence
• S. Lee Kling Proton Therapy Center

Products and services

• Cancer Treatment Services

Quantifiable outcome

• 94% sensitivity and 87% specificity in endometrial cancer detection using AI-assisted OCT imaging
• +3 more outcomes

Named customers2 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability5 records

Feature5 records

Partnerships

Twelve partnerships are on record, tiered core and regional.

• Barnes-Jewish HospitalcoreStrategic or Co-development PartnerBarnes-Jewish Hospital is the largest hospital in Missouri and a member of BJC HealthCare. As the primary teaching hospital of WashU Medicine, it provides the clinical setting for Siteman Cancer Center. Recognized on U.S. News & World Report Honor Roll for 16+ years with 15 specialties ranked among the nation's best including cancer. First adult hospital in Missouri to receive Magnet Award.
• WashU Medicine (Washington University School of Medicine)coreStrategic or Co-development PartnerWashU Medicine provides 600+ research scientists and physicians who staff Siteman Cancer Center. Consistently ranked among top 5 medical schools nationally by U.S. News & World Report. 1,250 clinical faculty researchers and practitioners provide care for 430,000+ patients annually. Home to the Genome Sequencing Center and pioneering cancer research programs.
• BJC HealthCarecoreStrategic or Co-development PartnerOne of the largest nonprofit healthcare organizations in the U.S., serving the greater St. Louis, southern Illinois, and mid-Missouri regions with 26,000 employees across 13 hospitals and multiple outpatient locations. Provides administrative and operational infrastructure supporting Siteman's regional expansion.
• St. Louis Children's HospitalcoreStrategic or Co-development PartnerSeventh oldest pediatric hospital in the U.S., established 1879, with international reputation for pediatric medicine. Partnership established in 2016 creates 'Siteman Kids at St. Louis Children's Hospital' focused on caring for children and adolescents with cancer using latest treatments in a child-friendly setting.
• National Cancer Institute (NCI)coreStrategic or Co-development PartnerNCI is the principal federal agency for cancer research and training. Siteman holds NCI-designated Comprehensive Cancer Center status with 'Exceptional' rating. NCI provides Cancer Center Support Grant funding and SPORE grants for pancreatic, endometrial, and leukemia research totaling over $33 million.
• National Comprehensive Cancer Network (NCCN)coreStrategic or Co-development PartnerNonprofit alliance of world's premier cancer centers dedicated to improving quality and efficiency of cancer care. Siteman joined in 2006 as one of 28 founding/early members. Only NCCN member in Missouri. Siteman director Timothy Eberlein served as NCCN Board Chairman.
• Memorial Hospital ShilohregionalChannel Partner/ Reseller/ DistributorSiteman Cancer Center located on the Memorial Shiloh campus provides patients with convenient access to world-class cancer care provided by Washington University Physicians. Received American Cancer Society National Partner Award for Road To Recovery transportation program.
• Boone Hospital Center and Stewart Cancer CenterregionalChannel Partner/ Reseller/ DistributorFirst affiliate of the Siteman Cancer Network, joining in 2017. Located in Columbia, Missouri, the affiliation aims to improve health of individuals and communities through cancer research, treatment, and prevention.
• Phelps County Regional Medical Center and Delbert Day Cancer InstituteregionalChannel Partner/ Reseller/ DistributorJoined Siteman Cancer Network in 2018. Located in Rolla, Missouri, expanding Siteman's regional reach to serve additional communities in the state.
• Alton Memorial HospitalregionalChannel Partner/ Reseller/ DistributorJoined Siteman Cancer Network in 2019. Located in Alton, Illinois, expanding cancer care services to the Illinois side of the greater St. Louis region.
• SIH Cancer InstituteregionalChannel Partner/ Reseller/ DistributorFourth member of Siteman Cancer Network, joining in 2020. Located in Carterville, Illinois, further expanding access to cancer research, treatment, and prevention across the region.
• NIH/All of Us Research ProgramcoreStrategic or Co-development PartnerSiteman researchers analyzed data from NIH's All of Us Research Program comprising more than 10,000 US participants for studies on accelerated aging and early-onset cancers published in Nature Medicine.

Scale indicators7 records

Recent moves14 records

Expansion highlights6 records

Direct peers

• MD Anderson Cancer Center: The largest NCI-Designated Comprehensive Cancer Center in the U.S., operating as a UTHealth affiliate in Houston. Directly comparable as a top-tier academic cancer center delivering multidisciplinary treatment, research, and prevention at scale.
• Memorial Sloan Kettering Cancer Center: Premier NCI-Designated Comprehensive Cancer Center in New York with deep subspecialty programs, pioneering research, and 700+ clinical trials. Closest peer in terms of research intensity, clinical breadth, and prestige tier.
• Dana-Farber Cancer Institute: Harvard-affiliated NCI Comprehensive Cancer Center with deep translational research portfolio and tight integration with a top medical school. Comparable on research output, NCI designation, and academic medical partnership model.
• Mayo Clinic Comprehensive Cancer Center: NCI Comprehensive Cancer Center embedded within the multi-state Mayo Clinic health system. Comparable as an integrated academic cancer center with national referral base, clinical trial scale, and multispecialty depth.
• Fred Hutchinson Cancer Center: Seattle-based NCI Comprehensive Cancer Center with particular strength in bone marrow transplant, immunotherapy, and translational science. Comparable on research intensity, NCI designation, and partnership with a leading research university (University of Washington).
• Johns Hopkins Sidney Kimmel Cancer Center: NCI Comprehensive Cancer Center integrated with Johns Hopkins Medicine. Comparable as an academic medical center partnership model with deep subspecialty programs, translational research, and clinical trial portfolio.
• UCSF Helen Diller Family Comprehensive Cancer Center: NCI Comprehensive Cancer Center affiliated with UCSF, known for precision oncology and translational research. Comparable on NCI designation, academic partnership, and leadership in AI/digital diagnostics.
• Vanderbilt-Ingram Cancer Center: NCI Comprehensive Cancer Center at Vanderbilt University Medical Center with strength in translational research and clinical trials. Comparable as a private, nonprofit academic cancer center with similar research funding scale.
• University of Michigan Rogel Cancer Center: NCI Comprehensive Cancer Center at Michigan Medicine. Comparable as a Midwest academic cancer center with multidisciplinary care, research portfolio, and SPORE-funded translational programs.
• Stanford Cancer Institute: NCI-Designated Cancer Center at Stanford Medicine with leadership in precision oncology, immunotherapy, and AI-driven cancer research. Comparable on academic medical partnership model and innovation-driven research.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/SitemanCenter
• YouTubeyoutube.com/user/SitemanCancerCenter
• Facebookfacebook.com/SitemanCancerCenter
• LinkedInlinkedin.com/company/washington-university-in-st-louis
• Instagraminstagram.com/sitemancancercenter

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles12 records

Subsidiaries6 records

Funding overview

Funding rounds1 record

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Siteman Cancer Center